Lista de obras - Francisco Garcia-Canovas

4-Hydroxyanisole: The Most Suitable Monophenolic Substrate for Determining Spectrophotometrically the Monophenolase Activity of Polyphenol Oxidase from Fruits and Vegetables ⬇️

artículo científico publicado el 15 de mayo de 1998

A comparative study of the inactivation of wild-type, recombinant and two mutant horseradish peroxidase isoenzymes C by hydrogen peroxide and m-chloroperoxybenzoic acid.

artículo científico publicado en 1995

A comparative study of the purity, enzyme activity, and inactivation by hydrogen peroxide of commercially available horseradish peroxidase isoenzymes A and C

artículo científico publicado en 1996

A continuous spectrophotometric method for determining the monophenolase and diphenolase activities of apple polyphenol oxidase.

artículo científico publicado en 1995

A continuous spectrophotometric method for the determination of diphenolase activity of tyrosinase using 3,4-dihydroxymandelic acid

scientific article published on 01 June 1991

A continuous spectrophotometric method for the determination of monophenolase activity of tyrosinase using 3-methyl-2-benzothiazolinone hydrazone

artículo científico publicado en 1994

A kinetic study of simultaneous suicide inactivation and irreversible inhibition of an enzyme. Application to 1-aminocyclopropane-1-carboxylate (ACC) synthase inactivation by its substrate S-adenosylmethionine

artículo científico publicado en 1993

A kinetic study of the irreversible inhibition of an enzyme measured in the presence of coupled enzymes. Fluorescein isothiocyanate as inhibitor of the adenosinetriphosphatase activity from sarcoplasmic reticulum

artículo científico publicado en 1986

A kinetic study of the melanization pathway between L-tyrosine and dopachrome

scientific article published on 01 February 1987

A review on spectrophotometric methods for measuring the monophenolase and diphenolase activities of tyrosinase.

artículo científico publicado en 2007

Action mechanism of tyrosinase on meta- and para-hydroxylated monophenols

artículo científico publicado en 2000

Action of tyrosinase on alpha and beta-arbutin: A kinetic study

artículo científico publicado en 2017

Action of tyrosinase on ortho-substituted phenols: possible influence on browning and melanogenesis

scientific article published on 18 June 2012

An enzymatic colorimetric method for measuring naringin using 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid)(ABTS) in the presence of peroxidase

artículo científico publicado en 1990

Analysis and interpretation of the action mechanism of mushroom tyrosinase on monophenols and diphenols generating highly unstable o-quinones.

artículo científico publicado en 2001

Assay of acetylcholinesterase activity by potentiometric monitoring of acetylcholine

artículo científico publicado en 2012

Calculating molar absorptivities for quinones: application to the measurement of tyrosinase activity.

artículo científico publicado en 2006

Calibration of a Clark-Type oxygen electrode by tyrosinase-catalyzed oxidation of 4-tert-butylcatechol

artículo científico publicado el 1 de mayo de 1992

Catalase-like oxygen production by horseradish peroxidase must predominantly be an enzyme-catalyzed reaction.

artículo científico publicado en 2001

Catalysis and inactivation of tyrosinase in its action on hydroxyhydroquinone.

artículo científico publicado en 2014

Catalytic oxidation of 2,4,5-trihydroxyphenylalanine by tyrosinase: identification and evolution of intermediates

artículo científico publicado el 20 de noviembre de 1992

Catalytic oxidation of o-aminophenols and aromatic amines by mushroom tyrosinase

artículo científico publicado en 2011

Characterization of the action of tyrosinase on resorcinols.

artículo científico publicado en 2016

Chemical and enzymatic oxidation of 4-methylcatechol in the presence and absence of L-serine. Spectrophotometric determination of intermediates.

artículo científico publicado en 1987

Cinnamate of inulin as a vehicle for delivery of colonic drugs

artículo científico publicado en 2014

Compound I formation in artichoke (Cynara scolymus L.) peroxidase is modulated by the equilibrium between pentacoordinated and 6-aquo hexacoordinated forms of the heme and by calcium ions.

artículo científico publicado en 2003

Determination of hemoglobin through its peroxidase activity on chlorpromazine

scientific article published on 01 July 1991

Deuterium isotope effect on the oxidation of monophenols and o-diphenols by tyrosinase.

artículo científico publicado en 2004

Direct immobilization of tyrosinase enzyme from natural mushrooms (Agaricus bisporus) on D-sorbitol cinnamic ester

artículo científico publicado en 2006

Discrimination between alternative substrates and inhibitors of tyrosinase

artículo científico publicado en 2015

Effect of ferrous ions on the monophenolase activity of tyrosinase

scientific article published on 01 June 1993

Effect of pH on the oxidation pathway of dopamine catalyzed by tyrosinase.

artículo científico publicado en 1991

Effects of tetrahydropterines on the generation of quinones catalyzed by tyrosinase.

artículo científico publicado en 2010

Effects of the immobilization supports on the catalytic properties of immobilized mushroom tyrosinase: a comparative study using several substrates

scientific article published on 17 May 2007

Ellagic acid: characterization as substrate of polyphenol oxidase.

artículo científico publicado en 2009

Enzymatic method with polyphenol oxidase for the determination of cysteine and N-acetylcysteine.

artículo científico publicado en 2005

Enzyme inactivation analysis for industrial blanching applications: comparison of microwave, conventional, and combination heat treatments on mushroom polyphenoloxidase activity

scientific article published on 01 November 1999

Expressions for the fractional modification in different monocyclic enzyme cascade systems: analysis of their validity tested by numerical integration.

artículo científico publicado en 2006

Final phase of enzyme reactions following a Michaelis-Menten mechanisms in which the free enzyme and/or the enzyme-substrate complex are unstable.

artículo científico publicado en 1994

General linear compartment model with zero input: I. Kinetic equations.

artículo científico publicado en 1995

General linear compartment model with zero input: III. First passage residence time of enzyme systems

artículo científico publicado en 1995

Generation of hydrogen peroxide in the melanin biosynthesis pathway.

artículo científico publicado en 2009

Hydrogen peroxide helps in the identification of monophenols as possible substrates of tyrosinase

scientific article published on 07 December 2013

Hydroxylation of p-substituted phenols by tyrosinase: further insight into the mechanism of tyrosinase activity.

artículo científico publicado en 2012

Inactivation of peroxidase by hydrogen peroxide and its protection by a reductant agent

artículo científico publicado en 1990

Indirect inactivation of tyrosinase in its action on 4-tert-butylphenol.

artículo científico publicado en 2013

Inhibition by L-ascorbic acid and other antioxidants of the 2.2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) oxidation catalyzed by peroxidase: a new approach for determining total antioxidant status of foods

scientific article published on 01 May 1996

Inhibition of Stenotrophomonas maltophilia dihydrofolate reductase by methotrexate: a single slow-binding process

artículo científico publicado en 2007

Kinetic analysis of a general model of activation of aspartic proteinase zymogens.

artículo científico publicado en 2006

Kinetic analysis of enzyme reactions with slow-binding inhibition.

artículo científico publicado en 1999

Kinetic analysis of enzyme systems with suicide substrate in the presence of a reversible, uncompetitive inhibitor.

artículo científico publicado en 2001

Kinetic analysis of reversible closed bicyclic enzyme cascades covering the whole course of the reaction.

artículo científico publicado en 1994

Kinetic characterisation of o-aminophenols and aromatic o-diamines as suicide substrates of tyrosinase ⬇️

artículo científico publicado el 10 de febrero de 2012

Kinetic characterisation of the reaction mechanism of mushroom tyrosinase on tyramine/dopamine and L-tyrosine methyl esther/L-dopa methyl esther.

artículo científico publicado en 2002

Kinetic characterization of the enzymatic and chemical oxidation of the catechins in green tea.

artículo científico publicado en 2008

Kinetic characterization of the oxidation of carbidopa and benserazide by tyrosinase and peroxidase.

artículo científico publicado en 2009

Kinetic characterization of the oxidation of chlorogenic acid by polyphenol oxidase and peroxidase. Characteristics of the o-quinone

artículo científico publicado en 2007

Kinetic characterization of the oxidation of esculetin by polyphenol oxidase and peroxidase

artículo científico publicado en 2007

Kinetic characterization of the substrate specificity and mechanism of mushroom tyrosinase

scientific article published on 01 March 2000

Kinetic study of the activation process of frog epidermis pro-tyrosinase by trypsin

scientific article published on 01 January 1983

Kinetic study of the effects of calcium ions on cationic artichoke (Cynara scolymus L.) peroxidase: calcium binding, steady-state kinetics and reactions with hydrogen peroxide.

artículo científico publicado en 2004

Kinetic study of the inactivation of ascorbate peroxidase by hydrogen peroxide.

artículo científico publicado en 2000

Kinetic study of the oxidation of quercetin by mushroom tyrosinase.

artículo científico publicado en 2003

Kinetics of enzyme systems with unstable suicide substrates.

artículo científico publicado en 1998

Mean residence times in linear compartmental systems. Symbolic formulae for their direct evaluation.

artículo científico publicado en 2003

Mechanisms of compound I formation in heme peroxidases.

artículo científico publicado en 2002

Melanogenesis Inhibition Due to NADH ⬇️

artículo científico publicado el 7 de septiembre de 2010

Melanogenesis inhibition by tetrahydropterines.

artículo científico publicado en 2009

Method for the determination of molar absorptivities of thiol adducts formed from diphenolic substrates of polyphenol oxidase.

artículo científico publicado en 2002

Michaelis constants of mushroom tyrosinase with respect to oxygen in the presence of monophenols and diphenols

artículo científico publicado en 2002

Mitochondrial ATPase inactivation by interaction with its substrate

scientific article published on 01 April 1982

Opposite effects of peroxidase in the initial stages of tyrosinase-catalysed melanin biosynthesis.

artículo científico publicado en 2005

Optimizing enzyme assays with one or two coupling enzymes.

artículo científico publicado en 1981

Oxidation by mushroom tyrosinase of monophenols generating slightly unstable o-quinones.

artículo científico publicado en 2000

Oxymetric and spectrophotometric study of the ascorbate oxidase activity shown by frog epidermis tyrosinase

scientific article published on 01 August 1996

Production of o-diphenols by immobilized mushroom tyrosinase.

artículo científico publicado en 2008

Purification and Kinetic Characterization of an Anionic Peroxidase from Melon (Cucumis meloL.) Cultivated under Different Salinity Conditions

scientific article published on 01 May 2000

Purification and characterization of a new cationic peroxidase from fresh flowers of Cynara scolymus L

artículo científico publicado en 2003

Purification of cynarases from artichoke (Cynara scolymus L.): enzymatic properties of cynarase A.

artículo científico publicado en 2005

Quantification of the antioxidant capacity of different molecules and their kinetic antioxidant efficiencies

scientific article published on 01 February 2010

Reactivity of horseradish peroxidase compound II toward substrates: kinetic evidence for a two-step mechanism

scientific article published on 01 October 2000

Spectrophotometric Characterization of the Action of Tyrosinase on p-Coumaric and Caffeic Acids: Characteristics of o-Caffeoquinone.

artículo científico publicado en 2017

Steady-state study of the mechanism of dopa-oxidase activity of tyrosinase

scientific article published on 01 January 1983

Stereospecific inactivation of tyrosinase by L- and D-ascorbic acid.

artículo científico publicado en 2008

Stereospecificity of mushroom tyrosinase immobilized on a chiral and a nonchiral support

artículo científico publicado en 2007

Stopped-flow and steady-state study of the diphenolase activity of mushroom tyrosinase

scientific article published on 01 August 2000

Structural and kinetic considerations on the catalysis of deoxyarbutin by tyrosinase.

artículo científico publicado en 2017

Study of tyrosine and dopa enantiomers as tyrosinase substrates initiating L- and D-melanogenesis pathways

artículo científico publicado en 2020

Suicide inactivation of the diphenolase and monophenolase activities of tyrosinase.

artículo científico publicado en 2010

Suicide inactivation of tyrosinase in its action on tetrahydropterines

artículo científico publicado en 2011

Tea polyphenol epigallocatechin-3-gallate inhibits ergosterol synthesis by disturbing folic acid metabolism in Candida albicans

scientific article published on 03 April 2006

Tetrahydrofolic Acid is a potent suicide substrate of mushroom tyrosinase

artículo científico publicado en 2011

The Relationship between the IC<sub>50</sub> Values and the Apparent Inhibition Constant in the Study of Inhibitors of Tyrosinase Diphenolase Activity Helps Confirm the Mechanism of Inhibition

artículo científico publicado en 2022

The anti-inflammatory and anti-cancer properties of epigallocatechin-3-gallate are mediated by folate cycle disruption, adenosine release and NF-kappaB suppression.

artículo científico publicado en 2008

The antifolate activity of tea catechins.

artículo científico publicado en 2005

The inactivation of horseradish peroxidase isoenzyme A2 by hydrogen peroxide: an example of partial resistance due to the formation of a stable enzyme intermediate.

artículo científico publicado en 2001

Thermal inactivation of mushroom polyphenoloxidase employing 2450 MHz microwave radiation

scientific article published on 01 August 1999

Time course equations of the amount of substance in a linear compartmental system and their computerized derivation.

artículo científico publicado en 2001

Transient phase of enzyme reactions. Time course equations of the strict and the rapid equilibrium conditions and their computerized derivation.

artículo científico publicado en 1999

Tyrosinase-catalyzed hydroxylation of hydroquinone, a depigmenting agent, to hydroxyhydroquinone: A kinetic study

scientific article published on 04 May 2014

Tyrosinase: kinetic analysis of the transient phase and the steady state.

artículo científico publicado en 1994

Unification for the expression of the monophenolase and diphenolase activities of tyrosinase

artículo científico publicado en 2002

Use of a windows program for simulation of the progress curves of reactants and intermediates involved in enzyme-catalyzed reactions.

artículo científico publicado en 2000

Lista de obras de Francisco Garcia-Canovas

4-Hydroxyanisole: The Most Suitable Monophenolic Substrate for Determining Spectrophotometrically the Monophenolase Activity of Polyphenol Oxidase from Fruits and Vegetables ⬇️

A comparative study of the inactivation of wild-type, recombinant and two mutant horseradish peroxidase isoenzymes C by hydrogen peroxide and m-chloroperoxybenzoic acid.

A comparative study of the purity, enzyme activity, and inactivation by hydrogen peroxide of commercially available horseradish peroxidase isoenzymes A and C

A continuous spectrophotometric method for determining the monophenolase and diphenolase activities of apple polyphenol oxidase.

A continuous spectrophotometric method for the determination of diphenolase activity of tyrosinase using 3,4-dihydroxymandelic acid

A continuous spectrophotometric method for the determination of monophenolase activity of tyrosinase using 3-methyl-2-benzothiazolinone hydrazone

A kinetic study of simultaneous suicide inactivation and irreversible inhibition of an enzyme. Application to 1-aminocyclopropane-1-carboxylate (ACC) synthase inactivation by its substrate S-adenosylmethionine

A kinetic study of the irreversible inhibition of an enzyme measured in the presence of coupled enzymes. Fluorescein isothiocyanate as inhibitor of the adenosinetriphosphatase activity from sarcoplasmic reticulum

A kinetic study of the melanization pathway between L-tyrosine and dopachrome

A review on spectrophotometric methods for measuring the monophenolase and diphenolase activities of tyrosinase.

Action mechanism of tyrosinase on meta- and para-hydroxylated monophenols

Action of tyrosinase on alpha and beta-arbutin: A kinetic study

Action of tyrosinase on ortho-substituted phenols: possible influence on browning and melanogenesis

An enzymatic colorimetric method for measuring naringin using 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid)(ABTS) in the presence of peroxidase

Analysis and interpretation of the action mechanism of mushroom tyrosinase on monophenols and diphenols generating highly unstable o-quinones.

Assay of acetylcholinesterase activity by potentiometric monitoring of acetylcholine

Calculating molar absorptivities for quinones: application to the measurement of tyrosinase activity.

Calibration of a Clark-Type oxygen electrode by tyrosinase-catalyzed oxidation of 4-tert-butylcatechol

Catalase-like oxygen production by horseradish peroxidase must predominantly be an enzyme-catalyzed reaction.

Catalysis and inactivation of tyrosinase in its action on hydroxyhydroquinone.

Catalytic oxidation of 2,4,5-trihydroxyphenylalanine by tyrosinase: identification and evolution of intermediates

Catalytic oxidation of o-aminophenols and aromatic amines by mushroom tyrosinase

Characterization of the action of tyrosinase on resorcinols.

Chemical and enzymatic oxidation of 4-methylcatechol in the presence and absence of L-serine. Spectrophotometric determination of intermediates.

Cinnamate of inulin as a vehicle for delivery of colonic drugs

Compound I formation in artichoke (Cynara scolymus L.) peroxidase is modulated by the equilibrium between pentacoordinated and 6-aquo hexacoordinated forms of the heme and by calcium ions.

Determination of hemoglobin through its peroxidase activity on chlorpromazine

Deuterium isotope effect on the oxidation of monophenols and o-diphenols by tyrosinase.

Direct immobilization of tyrosinase enzyme from natural mushrooms (Agaricus bisporus) on D-sorbitol cinnamic ester

Discrimination between alternative substrates and inhibitors of tyrosinase

Effect of ferrous ions on the monophenolase activity of tyrosinase

Effect of pH on the oxidation pathway of dopamine catalyzed by tyrosinase.

Effects of tetrahydropterines on the generation of quinones catalyzed by tyrosinase.

Effects of the immobilization supports on the catalytic properties of immobilized mushroom tyrosinase: a comparative study using several substrates

Ellagic acid: characterization as substrate of polyphenol oxidase.

Enzymatic method with polyphenol oxidase for the determination of cysteine and N-acetylcysteine.

Enzyme inactivation analysis for industrial blanching applications: comparison of microwave, conventional, and combination heat treatments on mushroom polyphenoloxidase activity

Expressions for the fractional modification in different monocyclic enzyme cascade systems: analysis of their validity tested by numerical integration.

Final phase of enzyme reactions following a Michaelis-Menten mechanisms in which the free enzyme and/or the enzyme-substrate complex are unstable.

General linear compartment model with zero input: I. Kinetic equations.

General linear compartment model with zero input: III. First passage residence time of enzyme systems

Generation of hydrogen peroxide in the melanin biosynthesis pathway.

Hydrogen peroxide helps in the identification of monophenols as possible substrates of tyrosinase

Hydroxylation of p-substituted phenols by tyrosinase: further insight into the mechanism of tyrosinase activity.

Inactivation of peroxidase by hydrogen peroxide and its protection by a reductant agent

Indirect inactivation of tyrosinase in its action on 4-tert-butylphenol.

Inhibition by L-ascorbic acid and other antioxidants of the 2.2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) oxidation catalyzed by peroxidase: a new approach for determining total antioxidant status of foods

Inhibition of Stenotrophomonas maltophilia dihydrofolate reductase by methotrexate: a single slow-binding process

Kinetic analysis of a general model of activation of aspartic proteinase zymogens.

Kinetic analysis of enzyme reactions with slow-binding inhibition.

Kinetic analysis of enzyme systems with suicide substrate in the presence of a reversible, uncompetitive inhibitor.

Kinetic analysis of reversible closed bicyclic enzyme cascades covering the whole course of the reaction.

Kinetic characterisation of o-aminophenols and aromatic o-diamines as suicide substrates of tyrosinase ⬇️

Kinetic characterisation of the reaction mechanism of mushroom tyrosinase on tyramine/dopamine and L-tyrosine methyl esther/L-dopa methyl esther.

Kinetic characterization of the enzymatic and chemical oxidation of the catechins in green tea.

Kinetic characterization of the oxidation of carbidopa and benserazide by tyrosinase and peroxidase.

Kinetic characterization of the oxidation of chlorogenic acid by polyphenol oxidase and peroxidase. Characteristics of the o-quinone

Kinetic characterization of the oxidation of esculetin by polyphenol oxidase and peroxidase

Kinetic characterization of the substrate specificity and mechanism of mushroom tyrosinase

Kinetic study of the activation process of frog epidermis pro-tyrosinase by trypsin

Kinetic study of the effects of calcium ions on cationic artichoke (Cynara scolymus L.) peroxidase: calcium binding, steady-state kinetics and reactions with hydrogen peroxide.

Kinetic study of the inactivation of ascorbate peroxidase by hydrogen peroxide.

Kinetic study of the oxidation of quercetin by mushroom tyrosinase.

Kinetics of enzyme systems with unstable suicide substrates.

Mean residence times in linear compartmental systems. Symbolic formulae for their direct evaluation.

Mechanisms of compound I formation in heme peroxidases.

Melanogenesis Inhibition Due to NADH ⬇️

Melanogenesis inhibition by tetrahydropterines.

Method for the determination of molar absorptivities of thiol adducts formed from diphenolic substrates of polyphenol oxidase.

Michaelis constants of mushroom tyrosinase with respect to oxygen in the presence of monophenols and diphenols

Mitochondrial ATPase inactivation by interaction with its substrate

Opposite effects of peroxidase in the initial stages of tyrosinase-catalysed melanin biosynthesis.

Optimizing enzyme assays with one or two coupling enzymes.

Oxidation by mushroom tyrosinase of monophenols generating slightly unstable o-quinones.

Oxymetric and spectrophotometric study of the ascorbate oxidase activity shown by frog epidermis tyrosinase

Production of o-diphenols by immobilized mushroom tyrosinase.

Purification and Kinetic Characterization of an Anionic Peroxidase from Melon (Cucumis meloL.) Cultivated under Different Salinity Conditions

Purification and characterization of a new cationic peroxidase from fresh flowers of Cynara scolymus L

Purification of cynarases from artichoke (Cynara scolymus L.): enzymatic properties of cynarase A.