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Lista de obras de Heinrich Sticht

11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

artículo científico publicado en 2016

A Metadynamics-Based Protocol for the Determination of GPCR-Ligand Binding Modes

artículo científico publicado en 2019

A Multiple Piccolino-RIBEYE Interaction Supports Plate-Shaped Synaptic Ribbons in Retinal Neurons

artículo científico publicado en 2019

A common structural mechanism underlying GCMB mutations that cause hypoparathyroidism

A comparative study of HIV-1 and HTLV-I protease structure and dynamics reveals a conserved residue interaction network

artículo científico publicado en 2011

A computational strategy for the prediction of functional linear peptide motifs in proteins

artículo científico publicado en 2007

A dual phenotype of periventricular nodular heterotopia and frontometaphyseal dysplasia in one patient caused by a single FLNA mutation leading to two functionally different aberrant transcripts

artículo científico publicado en 2004

A modeling strategy for G-protein coupled receptors

article

A molecular model for the differential activation of STAT3 and STAT6 by the herpesviral oncoprotein tip.

artículo científico publicado en 2012

A mutation in the β-subunit of ENaC identified in a patient with cystic fibrosis-like symptoms has a gain-of-function effect

artículo científico publicado en 2012

A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na+ self inhibition

artículo científico publicado en 2010

A new redox-dependent mechanism of MMP-1 activity control comprising reduced low-molecular-weight thiols and oxidizing radicals.

artículo científico publicado en 2008

A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency

artículo científico publicado en 2014

A proline to glycine mutation in the Lck SH3-domain affects conformational sampling and increases ligand binding affinity

artículo científico publicado en 2007

A protein-specifically adapted scoring function for the reranking of docking solutions

scholarly article by Wolfgang Müller published in January 2007

A severe congenital myasthenic syndrome with "dropped head" caused by novel MUSK mutations.

artículo científico publicado en 2015

A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions

artículo científico publicado en 2015

A tight lower bound on the mutual information of a binary and an arbitrary finite random variable as a function of the variational distance

A two-alpha-helix extra domain mediates the halophilic character of a plant-type ferredoxin from halophilic archaea

artículo científico publicado en 2005

AMBER force-field parameters for phosphorylated amino acids in different protonation states: phosphoserine, phosphothreonine, phosphotyrosine, and phosphohistidine

artículo científico publicado en 2005

AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability

artículo científico publicado en 2017

Agonist Binding and G Protein Coupling in Histamine H2 Receptor: A Molecular Dynamics Study

scientific article published on 12 September 2020

Alanine-glyoxylate aminotransferase 2 (AGXT2) polymorphisms have considerable impact on methylarginine and β-aminoisobutyrate metabolism in healthy volunteers

artículo científico publicado en 2014

Allergic cross-reactivity made visible: solution structure of the major cherry allergen Pru av 1

artículo científico publicado en 2001

Alpha-helix nucleation by a calcium-binding peptide loop

artículo científico publicado en 1999

Amino-Terminal Processing of Helicobacter pylori Serine Protease HtrA: Role in Oligomerization and Activity Regulation.

artículo científico publicado en 2018

Amyloid-beta42 oligomer structures from fibrils: a systematic molecular dynamics study

artículo científico publicado en 2010

Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity.

artículo científico publicado en 2015

An information-theoretic classification of amino acids for the assessment of interfaces in protein-protein docking

artículo científico publicado en 2013

An inhibitory peptide derived from the α-subunit of the epithelial sodium channel (ENaC) shows a helical conformation

artículo científico publicado en 2012

Analysis of amino acid residues in the predicted transmembrane pore influencing transport kinetics of the hepatic drug transporter organic anion transporting polypeptide 1B1 (OATP1B1).

artículo científico publicado en 2016

Analysis of naturally occurring mutations in the human uptake transporter NaCT important for bone and brain development and energy metabolism.

artículo científico publicado en 2018

Analysis of the structure-activity relationship of four herpesviral UL97 subfamily protein kinases reveals partial but not full functional conservation

artículo científico publicado en 2006

Antitermination in bacteriophage λ

scholarly article by Manuela Schärpf et al published April 2000 in FEBS Journal

Application of information theory to feature selection in protein docking

artículo científico publicado en 2011

Autosomal-Recessive Mutations in the tRNA Splicing Endonuclease Subunit TSEN15 Cause Pontocerebellar Hypoplasia and Progressive Microcephaly

artículo científico publicado en 2016

Autosomal-Recessive Mutations in the tRNA Splicing Endonuclease Subunit TSEN15 Cause Pontocerebellar Hypoplasia and Progressive Microcephaly

artículo científico publicado en 2016

B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies

artículo científico publicado en 2011

Biallelic SEMA3A defects cause a novel type of syndromic short stature.

artículo científico publicado en 2013

Binding of histamine to the H1 receptor-a molecular dynamics study

artículo científico publicado en 2018

Binding properties of SUMO-interacting motifs (SIMs) in yeast

Binding, domain orientation, and dynamics of the Lck SH3-SH2 domain pair and comparison with other Src-family kinases

artículo científico publicado en 2005

CD and NMR studies of prion protein (PrP) helix 1. Novel implications for its role in the PrPC-->PrPSc conversion process

artículo científico publicado en 2003

CD83 and GRASP55 interact in human dendritic cells

artículo científico publicado en 2015

CD83 is a dimer: Comparative analysis of monomeric and dimeric isoforms

artículo científico publicado en 2005

CTCF variants in 39 individuals with a variable neurodevelopmental disorder broaden the mutational and clinical spectrum

artículo científico publicado en 2019

Casein kinase 2-dependent serine phosphorylation of MuSK regulates acetylcholine receptor aggregation at the neuromuscular junction

artículo científico publicado en 2006

Channel Estimation for Diffusive Molecular Communications ⬇️

Channel estimation techniques for diffusion-based molecular communications ⬇️

Characterization of Lck-binding elements in the herpesviral regulatory Tip protein

artículo científico publicado en 2004

Characterization of Recombinant Human Cytomegaloviruses Encoding IE1 Mutants L174P and 1-382 Reveals that Viral Targeting of PML Bodies Perturbs both Intrinsic and Innate Immune Responses

artículo científico publicado en 2015

Characterization of a discontinuous neutralizing epitope on glycoprotein B of human cytomegalovirus

artículo científico publicado en 2013

Characterization of a single-chain variable fragment recognizing a linear epitope of aβ: a biotechnical tool for studies on Alzheimer's disease?

artículo científico publicado en 2013

Characterization of two mutations in the SPTLC1 subunit of serine palmitoyltransferase associated with hereditary sensory and autonomic neuropathy type I.

artículo científico publicado en 2011

Characterizing the Interaction between the HTLV-1 Transactivator Tax-1 with Transcription Elongation Factor ELL2 and Its Impact on Viral Transactivation

artículo científico publicado en 2021

Clinical relevance of systematic phenotyping and exome sequencing in patients with short stature.

artículo científico publicado en 2017

Combining independent drug classes into superior, synergistically acting hybrid molecules.

artículo científico publicado en 2010

Confirmation of mutations in PROSC as a novel cause of vitamin B 6 -dependent epilepsy.

artículo científico publicado en 2017

Conformational Dynamics of Herpesviral NEC Proteins in Different Oligomerization States

artículo científico publicado en 2018

Conformational stability of fibrillar amyloid-beta oligomers via protofilament pair formation - a systematic computational study

artículo científico publicado en 2013

Conformational switch upon phosphorylation: human CDK inhibitor p19INK4d between the native and partially folded state

artículo científico publicado en 2009

Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83.

artículo científico publicado en 2017

Crystal Structure of the Human Cytomegalovirus pUL50-pUL53 Core Nuclear Egress Complex Provides Insight into a Unique Assembly Scaffold for Virus-Host Protein Interactions

artículo científico publicado en 2015

Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs

artículo científico publicado en 2007

Crystal structure of cytomegalovirus IE1 protein reveals targeting of TRIM family member PML via coiled-coil interactions

artículo científico publicado en 2014

Cytomegaloviral proteins that associate with the nuclear lamina: components of a postulated nuclear egress complex

artículo científico publicado en 2009

DAPK-HSF1 interaction as a positive-feedback mechanism stimulating TNF-induced apoptosis in colorectal cancer cells

artículo científico publicado en 2014

DNA binding by Corynebacterium glutamicum TetR-type transcription regulator AmtR

artículo científico publicado en 2009

DYNC2LI1 mutations broaden the clinical spectrum of dynein-2 defects

scientific journal article

De Novo Variants in MAPK8IP3 Cause Intellectual Disability with Variable Brain Anomalies

scientific article published on 03 January 2019

De Novo Variants in the F-Box Protein FBXO11 in 20 Individuals with a Variable Neurodevelopmental Disorder

artículo científico publicado en 2018

De novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and females

artículo científico publicado en 2015

De novo mutations in the genome organizer CTCF cause intellectual disability.

artículo científico publicado en 2013

Diagnostic Yield and Novel Candidate Genes by Exome Sequencing in 152 Consanguineous Families With Neurodevelopmental Disorders.

artículo científico publicado en 2017

Differential contribution of EF-hands to the Ca²⁺-dependent activation in the plant two-pore channel TPC1.

artículo científico publicado en 2011

Disturbed Wnt Signalling due to a Mutation in CCDC88C Causes an Autosomal Recessive Non-Syndromic Hydrocephalus with Medial Diverticulum

artículo científico publicado en 2010

Dual selection pressure by drugs and HLA class I-restricted immune responses on human immunodeficiency virus type 1 protease

artículo científico publicado en 2007

Dynamic regulatory interaction between cytomegalovirus major tegument protein pp65 and protein kinase pUL97 in intracellular compartments, dense bodies and virions.

artículo científico publicado en 2017

Effect of HPr phosphorylation on structure, dynamics, and interactions in the course of transcriptional control

article

Effect of pathogenic mutations on the structure and dynamics of Alzheimer's A beta 42-amyloid oligomers.

artículo científico publicado en 2009

Effect of the SH3-SH2 domain linker sequence on the structure of Hck kinase

artículo científico publicado en 2010

Effects of histidine protonation and phosphorylation on histidine-containing phosphocarrier protein structure, dynamics, and physicochemical properties.

artículo científico publicado en 2007

Effects of the V82A and I54V mutations on the dynamics and ligand binding properties of HIV-1 protease

artículo científico publicado en 2010

Elucidation of the phenotypic spectrum and genetic landscape in primary and secondary microcephaly

artículo científico publicado en 2019

Equine infectious anemia virus Tat is a predominantly helical protein

artículo científico publicado en 1993

Equine infectious anemia virus transactivator is a homeodomain-type protein

artículo científico publicado en 1998

Erratum: Mimicking titration experiments with MD simulations: A protocol for the investigation of pH-dependent effects on proteins

artículo científico publicado en 2016

Erratum: Responsiveness of B cells is regulated by the hinge region of IgD

artículo científico publicado en 2015

Estrogen and progesterone receptors: from molecular structures to clinical targets

artículo científico publicado en 2009

Evidence for genetic overlap between adult onset Still's disease and hereditary periodic fever syndromes

artículo científico publicado en 2017

Evolutionary conserved networks of human height identify multiple Mendelian causes of short stature

scientific article published on 26 February 2019

Expanding the clinical and mutational spectrum of Kaufman oculocerebrofacial syndrome with biallelic UBE3B mutations

artículo científico

Expanding the clinical spectrum of COL1A1 mutations in different forms of glaucoma

artículo científico publicado en 2016

Expression, purification, and structural analysis of intracellular C-termini from metabotropic glutamate receptors

artículo científico publicado en 2013

Functional analysis of chemically synthesized derivatives of the human CC chemokine CCL15/HCC-2, a high affinity CCR1 ligand

artículo científico publicado en 2004

Functional and Structural Relevance of Conserved Positively Charged Lysine Residues in Organic Anion Transporting Polypeptide 1B3

article

Functional null mutations in the gonosomal homologue gene TBL1Y are associated with non-syndromic coarctation of the aorta

artículo científico publicado en 2012

Further corroboration of distinct functional features in SCN2A variants causing intellectual disability or epileptic phenotypes

artículo científico publicado en 2019

Further delineation of Pitt-Hopkins syndrome: phenotypic and genotypic description of 16 novel patients.

artículo científico publicado en 2008

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons

scientific article published on 30 December 2013

Genetic screening confirms heterozygous mutations in ACAN as a major cause of idiopathic short stature

artículo científico publicado en 2017

Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine

artículo científico publicado en 2014

Genotype-epigenotype-phenotype correlations in females with frontometaphyseal dysplasia

Genotype-phenotype evaluation of MED13L defects in the light of a novel truncating and a recurrent missense mutation.

artículo científico publicado en 2017

Group I metabotropic glutamate receptors bind to protein phosphatase 1C. Mapping and modeling of interacting sequences

scientific journal article

HIV-1 fusion is blocked through binding of GB Virus C E2-derived peptides to the HIV-1 gp41 disulfide loop [corrected]

artículo científico publicado en 2013

Haploinsufficiency of vascular endothelial growth factor related signaling genes is associated with tetralogy of Fallot

article

Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma

artículo científico publicado en 2009

Heterozygous and homozygous variants in STX1A cause a neurodevelopmental disorder with or without epilepsy

artículo científico publicado en 2022

Human TBX1 missense mutations cause gain of function resulting in the same phenotype as 22q11.2 deletions

artículo científico publicado en 2007

Hybrid compounds: from simple combinations to nanomachines

artículo científico publicado en 2012

Hypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly

artículo científico publicado en 2017

IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD

artículo científico publicado en 2018

Identification and characterization of a eukaryotically encoded rubredoxin in a cryptomonad alga.

artículo científico publicado en 2000

Identification of a Ninein (NIN) mutation in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotype

artículo científico publicado en 2013

Identification of a neutralizing epitope within antigenic domain 5 of glycoprotein B of human cytomegalovirus

artículo científico publicado en 2014

Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6)

scientific journal article

Identification of mutations in DYNC2LI1, a member of the mammalian cytoplasmic dynein 2 complex, expands the clinical spectrum of Jeune/ATD ciliopathies.

artículo científico publicado en 2015

Identification of the structural features that mediate binding specificity in the recognition of STAT proteins by dual-specificity phosphatases

scientific article published on 01 January 2012

Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models

artículo científico publicado en 2009

Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models

article

Impact of the C-terminal disulfide bond on the folding and stability of onconase

artículo científico publicado en 2010

Improving the efficiency of the Gaussian conformational database potential for the refinement of protein and nucleic acid structures

artículo científico publicado en 2001

In Silico Study of Camptothecin-Based Pro-Drugs Binding to Human Carboxylesterase 2

artículo científico publicado en 2024

IndependentNF1andPTPN11mutations in a family with neurofibromatosis-Noonan syndrome

Infantile Epileptic Encephalopathy, Transient Choreoathetotic Movements, and Hypersomnia due to a De Novo Missense Mutation in the SCN2A Gene

article

Inhibition of RAS activation due to a homozygous ezrin variant in patients with profound intellectual disability.

artículo científico publicado en 2015

Insight into the phosphoryl transfer of the Escherichia coli glucose phosphotransferase system from QM/MM simulations.

artículo científico publicado en 2008

Insights into amprenavir resistance in E35D HIV-1 protease mutation from molecular dynamics and binding free-energy calculations.

artículo científico publicado en 2006

Interaction of Glycolipids with the Macrophage Surface Receptor Mincle - a Systematic Molecular Dynamics Study.

artículo científico publicado en 2018

Investigation of the dynamics of the viral immediate-early protein 1 in different conformations and oligomerization states

artículo científico publicado en 2015

Loss of function of SVBP leads to autosomal recessive intellectual disability, microcephaly, ataxia, and hypotonia

artículo científico publicado en 2019

MAP4-dependent regulation of microtubule formation affects centrosome, cilia, and Golgi architecture as a central mechanism in growth regulation.

artículo científico publicado en 2014

Mimicking titration experiments with MD simulations: A protocol for the investigation of pH-dependent effects on proteins

artículo científico publicado en 2016

Missense Variants in RHOBTB2 Cause a Developmental and Epileptic Encephalopathy in Humans, and Altered Levels Cause Neurological Defects in Drosophila.

artículo científico publicado en 2017

Modulation of Recombinant Human α1 Glycine Receptors by Mono- and Disaccharides: A Kinetic Study

artículo científico publicado en 2016

Molecular Dynamics Simulation of Equine Infectious Anemia Virus Tat Protein in Water and in 40% Trifluoroethanol

artículo científico publicado en 1994

Molecular Dynamics Simulations of HIV-1 Protease Suggest Different Mechanisms Contributing to Drug Resistance.

artículo científico publicado en 2005

Molecular mechanism of HIV-1 gp120 mutations that reduce CD4 binding affinity

article

Molecular modeling of the interleukin-19 receptor complex. Novel aspects of receptor recognition in the interleukin-10 cytokine family

artículo científico publicado en 2004

Motif-Mediated Protein Interactions and their Role in Disease

Mouse ApoM displays an unprecedented seven-stranded lipocalin fold: folding decoy or alternative native fold?

artículo científico publicado en 2010

Mutations in CYP1B1 cause primary congenital glaucoma by reduction of either activity or abundance of the enzyme.

artículo científico publicado en 2008

Mutations in DCPS and EDC3 in autosomal recessive intellectual disability indicate a crucial role for mRNA decapping in neurodevelopment

artículo científico publicado en 2015

Mutations in IL36RN in patients with generalized pustular psoriasis

artículo científico publicado en 2013

Mutations in MEF2C from the 5q14.3q15 microdeletion syndrome region are a frequent cause of severe mental retardation and diminish MECP2 and CDKL5 expression.

artículo científico publicado en 2010

Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary dysplasia, lung hypoplasia, and mental retardation

artículo científico publicado en 2007

Mutations in herpes simplex virus gD protein affect receptor binding by different molecular mechanisms

artículo científico publicado en 2014

N(8)-acetylspermidine as a potential plasma biomarker for Snyder-Robinson syndrome identified by clinical metabolomics

artículo científico publicado en 2015

NDST1 missense mutations in autosomal recessive intellectual disability.

artículo científico publicado en 2014

Noncanonical NF-κB activation by the oncoprotein Tio occurs through a nonconserved TRAF3-binding motif

artículo científico publicado en 2013

Novel mode of phosphorylation-triggered reorganization of the nuclear lamina during nuclear egress of human cytomegalovirus

artículo científico publicado en 2010

Nuclear Egress Complexes of HCMV and Other Herpesviruses: Solving the Puzzle of Sequence Coevolution, Conserved Structures and Subfamily-Spanning Binding Properties

artículo científico publicado en 2020

Nuclear import of isoforms of the cytomegalovirus kinase pUL97 is mediated by differential activity of NLS1 and NLS2 both acting through classical importin-α binding.

artículo científico publicado en 2012

Null mutation in PGAP1 impairing Gpi-anchor maturation in patients with intellectual disability and encephalopathy

artículo científico publicado en 2014

Oral treatment with the d-enantiomeric peptide D3 improves the pathology and behavior of Alzheimer's Disease transgenic mice

artículo científico publicado en 2010

Overexpression, Purification, and Biochemical Characterization of the Extracellular Human CD83 Domain and Generation of Monoclonal Antibodies

artículo científico publicado en 2002

Oxidative stress-induced posttranslational modifications of human hemoglobin in erythrocytes

artículo científico publicado en 2012

PNUTS forms a trimeric protein complex with GABA(C) receptors and protein phosphatase 1.

artículo científico publicado en 2008

Palmoplantar Pustular Psoriasis Is Associated with Missense Variants in CARD14, but Not with Loss-of-Function Mutations in IL36RN in European Patients

artículo científico publicado en 2015

Peptides presenting the binding site of human CD4 for the HIV-1 envelope glycoprotein gp120.

artículo científico publicado en 2012

Phenotypic Variability in a Large Czech Family with a Dynamin 2–Associated Charcot-Marie-Tooth Neuropathy

article

Premature osteoarthritis as presenting sign of type II collagenopathy: a case report and literature review

artículo científico

Probing the Structure of the Escherichia coli Periplasmic Proteins HdeA and YmgD by Molecular Dynamics Simulations.

artículo científico publicado en 2016

Probing the potential of CnaB-type domains for the design of tag/catcher systems.

artículo científico publicado en 2017

Probing the role of intercalating protein sidechains for kink formation in DNA.

artículo científico publicado en 2018

Profiling of WDR36 missense variants in German patients with glaucoma

artículo científico publicado en 2008

Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus.

artículo científico

Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins

artículo científico publicado en 2016

Proteomic analysis of the multimeric nuclear egress complex of human cytomegalovirus

artículo científico publicado en 2014

Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study

artículo científico publicado en 2012

Rare Loss-of-Function Mutation in SERPINA3 in Generalized Pustular Psoriasis

artículo científico publicado en 2020

Rational Design of β-Sheet Ligands Against Aβ42-Induced Toxicity

article

Recognition of T-rich single-stranded DNA by the cold shock protein Bs-CspB in solution

artículo científico

Relevance of conserved lysine and arginine residues in transmembrane helices for the transport activity of organic anion transporting polypeptide 1B3.

artículo científico publicado en 2010

Responsiveness of B cells is regulated by the hinge region of IgD.

artículo científico publicado en 2015

Role of the N-terminus for the stability of an amyloid-β fibril with three-fold symmetry

artículo científico publicado en 2017

SPATA5 mutations cause a distinct autosomal recessive phenotype of intellectual disability, hypotonia and hearing loss

artículo científico publicado en 2016

SUMO E3 ligases are expressed in the retina and regulate SUMOylation of the metabotropic glutamate receptor 8b.

artículo científico publicado en 2011

Secondary structure and tertiary fold of the birch pollen allergen Bet v 1 in solution.

artículo científico publicado en 1996

Selection and Characterization of Tau Binding ᴅ-Enantiomeric Peptides with Potential for Therapy of Alzheimer Disease

artículo científico publicado en 2016

Sequence-specific 1H, 13C and 15N resonance assignments and secondary structure of [2Fe-2S] ferredoxin from Halobacterium salinarum

article

Sequence-specific 1H, 13C and 15N resonance assignments of the SH3-SH2 domain pair from the human tyrosine kinase Lck.

artículo científico publicado en 2003

Sequence-specific 1H, 13C and 15N resonance assignments of the major cherry allergen Pru a 1

artículo científico publicado en 2000

Severely incapacitating mutations in patients with extreme short stature identify RNA-processing endoribonuclease RMRP as an essential cell growth regulator

artículo científico publicado en 2005

Single expressed glycine receptor domains reconstitute functional ion channels without subunit-specific desensitization behavior

artículo científico publicado en 2014

Small ubiquitin-related modifier (SUMO) pathway-mediated enhancement of human cytomegalovirus replication correlates with a recruitment of SUMO-1/3 proteins to viral replication compartments

artículo científico publicado en 2013

Solution structure of cytochrome c6 from the thermophilic cyanobacterium Synechococcus elongatus.

artículo científico publicado en 1998

Solution structure of the glycosylated second type 2 module of fibronectin

artículo científico publicado en 1998

Solution structure of the human CC chemokine 2: A monomeric representative of the CC chemokine subtype

artículo científico publicado en 1999

Spatially clustering de novo variants in CYFIP2, encoding the cytoplasmic FMRP interacting protein 2, cause intellectual disability and seizures

artículo científico publicado en 2019

Specific residues of a conserved domain in the N terminus of the human cytomegalovirus pUL50 protein determine its intranuclear interaction with pUL53.

artículo científico publicado en 2012

Structural Basis for Species Selectivity in the HIV-1 gp120-CD4 Interaction: Restoring Affinity to gp120 in Murine CD4 Mimetic Peptides

artículo científico publicado en 2011

Structural analysis of the protein phosphatase 1 docking motif: molecular description of binding specificities identifies interacting proteins

artículo científico publicado en 2006

Structural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica

artículo científico publicado en 2017

Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody

artículo científico publicado en 2014

Structural characterization of Lyn-SH3 domain in complex with a herpesviral protein reveals an extended recognition motif that enhances binding affinity

artículo científico publicado en 2005

Structural characterization of intracellular C-terminal domains of group III metabotropic glutamate receptors

artículo científico publicado en 2011

Structural insight into the giant Ca²⁺-binding adhesin SiiE: implications for the adhesion of Salmonella enterica to polarized epithelial cells

artículo científico publicado en 2013

Structural investigation of the binding of a herpesviral protein to the SH3 domain of tyrosine kinase Lck

artículo científico publicado en 2002

Structural rearrangements of HIV-1 Tat-responsive RNA upon binding of neomycin B

artículo científico publicado en 2000

Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity

artículo científico publicado en 2001

Structure of Synechococcus elongatus [Fe2S2] ferredoxin in solution

artículo científico publicado en 1996

Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease

artículo científico publicado en 1995

Structure of human parathyroid hormone 1-37 in solution

artículo científico publicado en 1995

Structure-based functional analysis of effector protein SifA in living cells reveals motifs important for Salmonella intracellular proliferation

artículo científico publicado en 2017

Synthesis and characterization of the human CC chemokineHCC-2

artículo científico publicado en 1999

Synthetic Peptides as Protein Mimics

artículo científico publicado en 2015

Synthetic Protein Scaffolds Based on Peptide Motifs and Cognate Adaptor Domains for Improving Metabolic Productivity

artículo científico publicado en 2015

Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of East Asian-type Helicobacter pylori strains

artículo científico publicado en 2016

Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of Western-type Helicobacter pylori strains

artículo científico publicado en 2014

The C-terminal coiled-coil domain of Corynebacterium diphtheriae DIP0733 is crucial for interaction with epithelial cells and pathogenicity in invertebrate animal model systems

artículo científico publicado en 2018

The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain

artículo científico publicado en 2015

The Oligomeric Assemblies of Cytomegalovirus Core Nuclear Egress Proteins Are Associated with Host Kinases and Show Sensitivity to Antiviral Kinase Inhibitors

artículo científico publicado en 2022

The Prolyl Isomerase Pin1 Promotes the Herpesvirus-Induced Phosphorylation-Dependent Disassembly of the Nuclear Lamina Required for Nucleocytoplasmic Egress

artículo científico publicado en 2016

The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains

artículo científico publicado en 2004

The chemical class of quinazoline compounds provides a core structure for the design of anticytomegaloviral kinase inhibitors

artículo científico publicado en 2016

The clinical significance of small copy number variants in neurodevelopmental disorders

artículo científico publicado en 2014

The conformational stability of nonfibrillar amyloid-β peptide oligomers critically depends on the C-terminal peptide length

artículo científico publicado en 2014

The cyclin-dependent kinase ortholog pUL97 of human cytomegalovirus interacts with cyclins

artículo científico

The cytomegalovirus egress proteins pUL50 and pUL53 are translocated to the nuclear envelope through two distinct modes of nuclear import

artículo científico publicado en 2013

The degenerin region of the human bile acid-sensitive ion channel (BASIC) is involved in channel inhibition by calcium and activation by bile acids.

artículo científico publicado en 2018

The genetic basis for most patients with pustular skin disease remains elusive

artículo científico publicado en 2017

The human cytomegalovirus nuclear egress complex unites multiple functions: Recruitment of effectors, nuclear envelope rearrangement, and docking to nuclear capsids

artículo científico publicado en 2017

The interleukin-10 family of cytokines

artículo científico publicado en 2002

The pH-dependent Client Release from the Collagen-specific Chaperone HSP47 Is Triggered by a Tandem Histidine Pair

artículo científico publicado en 2016

The polynucleotide kinase 3′-phosphatase gene (PNKP) is involved in Charcot-Marie-Tooth disease (CMT2B2) previously related to MED25

artículo científico publicado en 2018

The role of recessive inheritance in early-onset epileptic encephalopathies: a combined whole-exome sequencing and copy number study

scientific article published on 14 December 2018

The structure of iron-sulfur proteins

artículo científico publicado en 1998

The structure of the coliphage HK022 Nun protein-lambda-phage boxB RNA complex. Implications for the mechanism of transcription termination

artículo científico publicado en 2001

The transcription regulator RbsR represents a novel interaction partner of the phosphoprotein HPr-Ser46-P in Bacillus subtilis

artículo científico publicado en 2006

Thymosin β4 and tissue transglutaminase. Molecular characterization of cyclic thymosin β4.

artículo científico publicado en 2013

Transfer of HTLV-1 p8 and Gag to target T-cells depends on VASP, a novel interaction partner of p8

scientific article published on 30 September 2020

Trifluoroethanol stabilizes a helix-turn-helix motif in equine infectious-anemia-virus trans-activator protein

artículo científico publicado en 1994

Two isoforms of the protein kinase pUL97 of human cytomegalovirus are differentially regulated in their nuclear translocation

artículo científico publicado en 2010

Two novel mutations in the insulin binding subunit of the insulin receptor gene without insulin binding impairment in a patient with Rabson-Mendenhall syndrome

artículo científico publicado en 2008

Validation of the reliability of computational O-GlcNAc prediction

artículo científico publicado en 2013

Variants in ASB10 are associated with open-angle glaucoma

artículo científico publicado en 2012

Variants in CPLX1 in two families with autosomal-recessive severe infantile myoclonic epilepsy and ID.

artículo científico publicado en 2017

Whole exome sequencing reveals a novel de novo FOXC1 mutation in a patient with unrecognized Axenfeld-Rieger syndrome and glaucoma

artículo científico publicado en 2015

enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrA

artículo científico publicado en 2019

pH-dependent molecular dynamics of vesicular stomatitis virus glycoprotein G.

artículo científico publicado en 2012

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