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A generic workflow for the characterization of therapeutic monoclonal antibodies-application to daratumumab

artículo científico publicado en 2019

A multi-target screening analysis in human plasma using fast liquid chromatography-hybrid tandem mass spectrometry (Part I)

scientific article published on 04 August 2010

A multi-target screening analysis in human plasma using fast liquid chromatography-hybrid tandem mass spectrometry (Part II)

artículo científico publicado en 2010

A novel online four-dimensional SECxSEC-IMxMS methodology for characterization of monoclonal antibody size variants

artículo científico publicado en 2018

A scoring approach for multi-platform acquisition in metabolomics

artículo científico publicado en 2019

A systematic investigation of sample diluents in modern supercritical fluid chromatography

artículo científico publicado en 2017

A systematic investigation of the effect of sample diluent on peak shape in hydrophilic interaction liquid chromatography

artículo científico publicado en 2010

A workflow for column interchangeability in liquid chromatography using modeling software and quality-by-design principles

artículo científico publicado en 2017

Achievable separation performance and analysis time in current liquid chromatographic practice for monoclonal antibody separations

artículo científico publicado en 2017

Adding a new separation dimension to MS and LC-MS: What is the utility of ion mobility spectrometry?

artículo científico publicado en 2017

Adsorption and recovery issues of recombinant monoclonal antibodies in reversed-phase liquid chromatography

artículo científico publicado en 2014

Advanced high-resolution chromatographic strategies for efficient isolation of natural products from complex biological matrices: from metabolite profiling to pure chemical entities

artículo científico publicado en 2024

Advanced technologies for exploring the chemical and functional properties of bioactive constituents in food

Advances in LC platforms for drug discovery

artículo científico publicado en 2010

Aminoglycoside analysis in food of animal origin with a zwitterionic stationary phase and liquid chromatography-tandem mass spectrometry

artículo científico publicado en 2015

An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates.

artículo científico publicado en 2017

An attempt to characterize the human Chorionic Gonadotropin protein by reversed phase liquid chromatography coupled with high-resolution mass spectrometry at the intact level

scientific article published on 02 August 2018

Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. I - Optimization of separation conditions

artículo científico publicado en 2016

Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. II- Identification of sub-units for the char

artículo científico publicado en 2016

Analysis of basic compounds by supercritical fluid chromatography: Attempts to improve peak shape and maintain mass spectrometry compatibility

artículo científico publicado en 2012

Analysis of peptides and proteins using sub-2 μm fully porous and sub 3-μm shell particles

artículo científico publicado en 2011

Analysis of recombinant monoclonal antibodies by RPLC: toward a generic method development approach

artículo científico publicado en 2012

Analysis of recombinant monoclonal antibodies in hydrophilic interaction chromatography: A generic method development approach

artículo científico publicado en 2017

Analytical Strategies for Doping Control Purposes: Needs, Challenges, and Perspectives

artículo científico publicado en 2015

Analytical aspects in doping control: Challenges and perspectives

artículo científico publicado en 2011

Analytical strategies for the determination of amino acids: Past, present and future trends

scientific article published on 22 October 2019

Analytical tools for the physicochemical profiling of drug candidates to predict absorption/distribution

artículo científico publicado en 2009

Antineoplastic drugs and their analysis: a state of the art review

artículo científico publicado en 2017

Apparent efficiency of serially coupled columns in gradient elution liquid chromatography: Extension to the combination of any column formats

scientific article published on 18 December 2018

Apparent efficiency of serially coupled columns in isocratic and gradient elution modes

artículo científico publicado en 2018

Applicability of Supercritical fluid chromatography-Mass spectrometry to metabolomics. II-Assessment of a comprehensive library of metabolites and evaluation of biological matrices

scientific article published on 07 March 2020

Applicability of supercritical fluid chromatography - mass spectrometry to metabolomics. I - Optimization of separation conditions for the simultaneous analysis of hydrophilic and lipophilic substances

artículo científico publicado en 2018

Applications of hydrophilic interaction chromatography to amino acids, peptides, and proteins

artículo científico publicado en 2015

Automated middle-up approach for the characterization of biotherapeutic products by combining on-line hinge-specific digestion with RPLC-HRMS analysis

artículo científico publicado en 2020

Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenation.

artículo científico publicado en 2017

Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometry

artículo científico publicado en 2018

Characterization of antibody drug conjugates by an innovative on-line four-dimensional HICxSEC-IM-MS methodology

scholarly article

Characterization of cation exchanger stationary phases applied for the separations of therapeutic monoclonal antibodies

artículo científico publicado en 2015

Characterization of charge variants for antibody-based biopharmaceuticals by mass spectrometry

scientific article published on 11 November 2019

Characterizing various monoclonal antibodies with milder reversed phase chromatography conditions

scientific article published on 29 July 2018

Chromatographic Performance of Silica-Based Stationary Phases in High Temperature Liquid Chromatography: Pharmaceutical Applications

artículo científico publicado en 2007

Chromatographic behaviour and comparison of column packed with sub-2 microm stationary phases in liquid chromatography

artículo científico publicado en 2006

Chromatographic, Electrophoretic, and Mass Spectrometric Methods for the Analytical Characterization of Protein Biopharmaceuticals

artículo científico publicado en 2015

Comparative study of recent wide-pore materials of different stationary phase morphology, applied for the reversed-phase analysis of recombinant monoclonal antibodies

artículo científico publicado en 2013

Comparison of columns packed with porous sub-2 microm particles and superficially porous sub-3 microm particles for peptide analysis at ambient and high temperature

artículo científico publicado en 2010

Comparison of liquid chromatography and supercritical fluid chromatography coupled to compact single quadrupole mass spectrometer for targeted in vitro metabolism assay.

artículo científico publicado en 2014

Comparison of originator and biosimilar therapeutic monoclonal antibodies using comprehensive two-dimensional liquid chromatography coupled with time-of-flight mass spectrometry

artículo científico publicado en 2016

Comparison of the most recent chromatographic approaches applied for fast and high resolution separations: Theory and practice

artículo científico

Comparison of ultra-high performance supercritical fluid chromatography and ultra-high performance liquid chromatography for the analysis of pharmaceutical compounds

artículo científico publicado en 2012

Comparison of various silica-based monoliths for the analysis of large biomolecules

artículo científico publicado en 2013

Composite resin vs resin cement for luting of indirect restorations: comparison of solubility and shrinkage behavior

artículo científico publicado en 2013

Comprehensive study on the effects of sodium and potassium additives in size exclusion chromatographic separations of protein biopharmaceuticals

artículo científico publicado en 2016

Computer assisted liquid chromatographic method development for the separation of therapeutic proteins.

artículo científico publicado en 2016

Computer-assisted UHPLC-MS method development and optimization for the determination of 24 antineoplastic drugs used in hospital pharmacy

scientific article published on 06 November 2018

Contribution of various types of liquid chromatography-mass spectrometry instruments to band broadening in fast analysis

artículo científico publicado en 2013

Corrigendum to "Protocols for the analytical characterization of therapeutic monoclonal antibodies. I-Non-denaturing chromatographic techniques" [J. Chromatogr. B 1058 (2017) 73-84].

artículo científico publicado en 2017

Coupling CE with atmospheric pressure photoionization MS for pharmaceutical basic compounds: optimization of operating parameters

artículo científico publicado en 2007

Coupling non-denaturing chromatography to mass spectrometry for the characterization of monoclonal antibodies and related products

artículo científico publicado en 2020

Coupling state-of-the-art supercritical fluid chromatography and mass spectrometry: from hyphenation interface optimization to high-sensitivity analysis of pharmaceutical compounds

artículo científico publicado en 2014

Coupling ultra high-pressure liquid chromatography with mass spectrometry: constraints and possible applications

artículo científico publicado en 2012

Coupling ultra high-pressure liquid chromatography with single quadrupole mass spectrometry for the analysis of a complex drug mixture

artículo científico publicado en 2008

Coupling ultra-high-pressure liquid chromatography with mass spectrometry

artículo científico publicado en 2010

Critical evaluation of fast size exclusion chromatographic separations of protein aggregates, applying sub-2 μm particles

artículo científico publicado en 2013

Current and future trends in UHPLC

artículo científico publicado en 2014

Current and future trends in reversed-phase liquid chromatography-mass spectrometry of therapeutic proteins

artículo científico publicado en 2020

Current possibilities of liquid chromatography for the characterization of antibody-drug conjugates

artículo científico publicado en 2017

Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future

artículo científico publicado en 2019

Detection Modes with High Temperature Liquid Chromatography—A Review

artículo científico publicado en 2005

Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies

artículo científico publicado en 2017

Determination of size variants by CE-SDS for approved therapeutic antibodies: Key implications of subclasses and light chain specificities

artículo científico publicado en 2020

Development of Comprehensive Online Two-Dimensional Liquid Chromatography/Mass Spectrometry Using Hydrophilic Interaction and Reversed-Phase Separations for Rapid and Deep Profiling of Therapeutic Antibodies.

artículo científico publicado en 2018

Development of Rapid Analytical Methods in the Laboratory of Pharmaceutical Analytical Chemistry (LCAP)

artículo científico publicado en 2005

Development of a 3D-LC/MS Workflow for Fast, Automated, and Effective Characterization of Glycosylation Patterns of Biotherapeutic Products

scientific article published on 04 March 2020

Development of a LC-MS/MS method for the determination of isomeric glutamyl peptides in food ingredients.

artículo científico publicado en 2017

Development of a fast workflow to screen the charge variants of therapeutic antibodies

artículo científico publicado en 2017

Development of an innovative salt-mediated pH gradient cation exchange chromatography method for the characterization of therapeutic antibodies

scientific article published on 07 September 2020

Direct identification of rituximab main isoforms and subunit analysis by online selective comprehensive two-dimensional liquid chromatography-mass spectrometry

artículo científico publicado en 2015

Drug Loading and Distribution of ADCs After Reduction or IdeS Digestion and Reduction

artículo científico publicado en 2020

Editorial for the special issue entitled "Biopharmaceuticals 2016".

artículo científico publicado en 2016

Editorial for the special issue entitled "supercritical fluid chromatography - mass spectrometry"

artículo científico publicado en 2018

Editorial for the special issue titled "Biopharmaceuticals 2020"

artículo científico publicado en 2020

Editorial for the virtual special issue SEP 2019

scientific article published on 15 January 2020

Effect of temperature in reversed phase liquid chromatography

artículo científico publicado en 2004

Enhanced method performances for conventional and chiral CE-ESI/MS analyses in plasma

artículo científico publicado en 2006

Estimation of pressure-, temperature- and frictional heating-related effects on proteins' retention under ultra-high-pressure liquid chromatographic conditions

artículo científico publicado en 2015

Estimation of the effects of longitudinal temperature gradients caused by frictional heating on the solute retention using fully porous and superficially porous sub-2μm materials

scientific article published on 18 July 2014

Evaluation and comparison of various separation techniques for the analysis of closely-related compounds of pharmaceutical interest

artículo científico publicado en 2013

Evaluation of Different Tandem MS Acquisition Modes to Support Metabolite Annotation in Human Plasma Using Ultra High-Performance Liquid Chromatography High-Resolution Mass Spectrometry for Untargeted Metabolomics

artículo científico publicado en 2020

Evaluation of a new wide pore core-shell material (Aeris WIDEPORE) and comparison with other existing stationary phases for the analysis of intact proteins

artículo científico publicado en 2012

Evaluation of a new wide-pore superficially porous material with carbon core and nanodiamond-polymer shell for the separation of proteins

scientific article published on 17 August 2015

Evaluation of additives on reversed-phase chromatography of monoclonal antibodies using a 1000 Å stationary phase

artículo científico publicado en 2019

Evaluation of columns packed with shell particles with compounds of pharmaceutical interest

artículo científico publicado en 2011

Evaluation of innovative stationary phase ligand chemistries and analytical conditions for the analysis of basic drugs by supercritical fluid chromatography

artículo científico publicado en 2016

Evaluation of new superficially porous particles with carbon core and nanodiamond-polymer shell for proteins characterization

scientific article published on 27 November 2014

Evaluation of recent very efficient wide-pore stationary phases for the reversed-phase separation of proteins

scientific article published on 28 June 2012

Evaluation of size exclusion chromatography columns packed with sub-3μm particles for the analysis of biopharmaceutical proteins

artículo científico publicado en 2016

Evaluation of stationary phases packed with superficially porous particles for the analysis of pharmaceutical compounds using supercritical fluid chromatography

artículo científico publicado en 2014

Evaluation of the coupling between ultra performance liquid chromatography and evaporative light scattering detector for selected phytochemical applications

artículo científico publicado en 2008

Evaluation of thermally pretreated silica stationary phases under hydrophilic interaction chromatography conditions.

artículo científico publicado en 2016

Evaluation of various HILIC materials for the fast separation of polar compounds

artículo científico publicado en 2010

Evaluation of various chromatographic approaches for the retention of hydrophilic compounds and MS compatibility

artículo científico publicado en 2013

Evolution and Current Trends in Liquid and Supercritical Fluid Chromatography

artículo científico publicado en 2014

Extending the limits of size exclusion chromatography: Simultaneous separation of free payloads and related species from antibody drug conjugates and their aggregates

artículo científico publicado en 2018

Fast analysis in liquid chromatography using small particle size and high pressure

artículo científico publicado en 2006

Fast and automated characterization of monoclonal antibody minor variants from cell cultures by combined Protein-A and multi-dimensional LC/MS methodologies

scientific article published on 22 May 2020

Fast and sensitive supercritical fluid chromatography - tandem mass spectrometry multi-class screening method for the determination of doping agents in urine.

artículo científico publicado en 2016

Fast chiral separation of drugs using columns packed with sub-2 microm particles and ultra-high pressure.

artículo científico publicado en 2010

Fast log P determination by ultra-high-pressure liquid chromatography coupled with UV and mass spectrometry detections

artículo científico publicado en 2009

First inter-laboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities

scientific article published on 23 August 2018

From proof of concept to the routine use of an automated and robust multi-dimensional liquid chromatography mass spectrometry workflow applied for the charge variant characterization of therapeutic antibodies

scientific article published on 27 November 2019

Glycosylation of biosimilars: Recent advances in analytical characterization and clinical implications

scientific article published on 22 August 2019

High performance affinity chromatography (HPAC) as a high-throughput screening tool in drug discovery to study drug-plasma protein interactions

artículo científico publicado en 2012

High resolution reversed phase analysis of recombinant monoclonal antibodies by ultra-high pressure liquid chromatography column coupling

artículo científico publicado en 2013

High throughput liquid chromatography with sub-2 microm particles at high pressure and high temperature

scientific article published on 17 August 2007

High throughput qualitative analysis of polyphenols in tea samples by ultra-high pressure liquid chromatography coupled to UV and mass spectrometry detectors

artículo científico publicado en 2010

High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method

scientific article published on 04 June 2018

High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists

artículo científico publicado en 2008

Hydrophilic Interaction Chromatography Hyphenated with Mass Spectrometry: A Powerful Analytical Tool for the Comparison of Originator and Biosimilar Therapeutic Monoclonal Antibodies at the Middle-up Level of Analysis

artículo científico publicado en 2017

Hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry: effect of electrospray ionization source geometry on sensitivity

artículo científico publicado en 2014

Hydrophobic interaction chromatography for the characterization of monoclonal antibodies and related products

artículo científico publicado en 2016

Hyphenation of size exclusion chromatography to native ion mobility mass spectrometry for the analytical characterization of therapeutic antibodies and related products

artículo científico publicado en 2018

Impact of mobile phase temperature on recovery and stability of monoclonal antibodies using recent reversed-phase stationary phases

artículo científico publicado en 2012

Impact of organic modifier and temperature on protein denaturation in hydrophobic interaction chromatography

artículo científico publicado en 2016

Impact of particle size gradients on the apparent efficiency of chromatographic columns

artículo científico publicado en 2019

Impact of the column on effluent pH in cation exchange pH gradient chromatography, a practical study

artículo científico publicado en 2020

Implementation of a generic liquid chromatographic method development workflow: Application to the analysis of phytocannabinoids and Cannabis sativa extracts

artículo científico publicado en 2018

Importance of instrumentation for fast liquid chromatography in pharmaceutical analysis

artículo científico

Importance of vial shape and type on the reproducibility of size exclusion chromatography measurement of monoclonal antibodies

artículo científico publicado en 2016

Improved quality-by-design compliant methodology for method development in reversed-phase liquid chromatography

artículo científico publicado en 2013

Improved separation by at-column dilution in preparative hydrophilic interaction chromatography

artículo científico publicado en 2017

Improving selectivity and performing online on-column fractioning in liquid chromatography for the separation of therapeutic biopharmaceutical products

scientific article published on 21 January 2020

In vivo characterisation of a novel water-soluble Cyclosporine A prodrug for the treatment of dry eye disease

artículo científico publicado en 2011

In vivo distribution and ex vivo permeation of cyclosporine A prodrug aqueous formulations for ocular application

artículo científico publicado en 2013

Influence of connection tubing in modern size exclusion chromatography and its impact on the characterization of mAbs

artículo científico publicado en 2017

Influence of pressure and temperature on molar volume and retention properties of peptides in ultra-high pressure liquid chromatography

artículo científico publicado en 2013

Innovative methodology to transfer conventional GC-MS heroin profiling to UHPLC-MS/MS.

artículo científico publicado en 2010

Intact protein analysis in the biopharmaceutical field

scientific article published on 28 January 2011

Interlaboratory and Interplatform Study of Steroids Collision Cross Section by Traveling Wave Ion Mobility Spectrometry

artículo científico publicado en 2020

Investigating the use of unconventional temperatures in supercritical fluid chromatography

scientific article published on 18 August 2020

Ion-exchange chromatography for the characterization of biopharmaceuticals

artículo científico

Is hydrophobic interaction chromatography the most suitable technique to characterize site-specific antibody-drug conjugates?

artículo científico publicado en 2018

Isolation and Identification of Isocoumarin Derivatives With Specific Inhibitory Activity Against Wnt Pathway and Metabolome Characterization of Lasiodiplodia venezuelensis ⬇️

scientific article published on 12 August 2021

Kinetic evaluation of new generation of column packed with 1.3 μm core-shell particles

artículo científico publicado en 2013

Lipophilicity determination of highly lipophilic compounds by liquid chromatography

artículo científico publicado en 2009

Liquid chromatography and supercritical fluid chromatography as alternative techniques to gas chromatography for the rapid screening of anabolic agents in urine

artículo científico publicado en 2016

Maximizing kinetic performance in supercritical fluid chromatography using state-of-the-art instruments

artículo científico publicado en 2013

Metabolite profiling of plant extracts by ultra-high-pressure liquid chromatography at elevated temperature coupled to time-of-flight mass spectrometry

article

Method development for pharmaceutics: Some solutions for tuning selectivity in reversed phase and hydrophilic interaction liquid chromatography

scientific article published on 28 January 2012

Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part I: salt gradient approach

scientific article published on 08 September 2014

Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part II: pH gradient approach

artículo científico publicado en 2014

Method transfer for fast liquid chromatography in pharmaceutical analysis: application to short columns packed with small particle. Part I: isocratic separation

artículo científico publicado en 2006

Method transfer for fast liquid chromatography in pharmaceutical analysis: application to short columns packed with small particle. Part II: gradient experiments

artículo científico publicado en 2007

Micro liquid chromatography coupled with evaporative light scattering detector at ambient and high temperature: optimization of the nebulization cell geometry

artículo científico publicado en 2008

Microemulsion electrokinetic chromatography hyphenated to atmospheric pressure photoionization mass spectrometry

artículo científico publicado en 2008

Modern analytical supercritical fluid chromatography using columns packed with sub-2 μm particles: a tutorial.

artículo científico

Monoclonal antibody N-glycosylation profiling using capillary electrophoresis - Mass spectrometry: Assessment and method validation

artículo científico publicado en 2017

Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches

artículo científico publicado en 2021

Multi-target screening of biological samples using LC-MS/MS: focus on chromatographic innovations

artículo científico publicado en 2014

Natural compounds analysis using liquid and supercritical fluid chromatography hyphenated to mass spectrometry: Evaluation of a new design of atmospheric pressure ionization source

artículo científico publicado en 2018

Negative gradient slope methods to improve the separation of closely eluting proteins

artículo científico publicado en 2020

New Findings in Liquid Chromatography in The Pharmaceutical Domain ⬇️

artículo científico publicado el 1 de enero de 2011

New developments and possibilities of wide-pore superficially porous particle technology applied for the liquid chromatographic analysis of therapeutic proteins

scientific article published on 05 June 2018

New insights in pharmaceutical analysis

artículo científico publicado en 2012

New prostaglandin analog formulation for glaucoma treatment containing cyclodextrins for improved stability, solubility and ocular tolerance

artículo científico publicado en 2015

New trends in fast and high-resolution liquid chromatography: a critical comparison of existing approaches

artículo científico publicado en 2009

New trends in reversed-phase liquid chromatographic separations of therapeutic peptides and proteins: theory and applications

artículo científico publicado en 2012

Non-invasive targeted iontophoretic delivery of cetuximab to skin

scientific article published on 27 February 2020

O22 The key role of analytical sciences in the discovery and characterization of bioactives from food and nutraceuticals

scholarly article by Alexandre Grand-Guillaume Perrenoud et al published September 2017 in Biochemical Pharmacology

On-tubing fluorescence measurements of the band broadening of contemporary injectors in ultra-high performance liquid chromatography.

artículo científico publicado en 2017

Optimization of non-linear gradient in hydrophobic interaction chromatography for the analytical characterization of antibody-drug conjugates

artículo científico publicado en 2016

Optimization of the coupling of high-temperature liquid chromatography and flame ionization detection application to the separations of alcohols

artículo científico publicado en 2005

Optimized liquid chromatography–mass spectrometry approach for the isolation of minor stress biomarkers in plant extracts and their identification by capillary nuclear magnetic resonance

article

Optimized selection of liquid chromatography conditions for wide range analysis of natural compounds.

artículo científico publicado en 2017

Orthogonal Middle-up Approaches for Characterization of the Glycan Heterogeneity of Etanercept by Hydrophilic Interaction Chromatography Coupled to High-Resolution Mass Spectrometry

artículo científico publicado en 2018

Peak capacity optimisation for high resolution peptide profiling in complex mixtures by liquid chromatography coupled to time-of-flight mass spectrometry: application to the Conus consors cone snail venom

artículo científico publicado en 2012

Pharmaceutical applications on columns packed with sub-2 microm particles.

artículo científico publicado en 2008

Plant Metabolomics – Strategies for Biomarker Detection, Isolation, and Identification

article

Possibilities of new generation columns packed with 1.3μm core-shell particles in gradient elution mode

artículo científico publicado en 2013

Possibilities of retention modeling and computer assisted method development in supercritical fluid chromatography

artículo científico publicado en 2015

Potential of hydrophilic interaction chromatography for the analytical characterization of protein biopharmaceuticals

artículo científico publicado en 2016

Practical considerations on the particle size and permeability of ion-exchange columns applied to biopharmaceutical separations

artículo científico publicado en 2019

Practical constraints in the kinetic plot representation of chromatographic performance data: theory and application to experimental data.

artículo científico publicado en 2006

Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatography, part 1: optimization of the mobile phase

artículo científico publicado en 2015

Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatoraphy, part 2: Optimization of the phase system

artículo científico publicado en 2016

Practical method transfer from high performance liquid chromatography to ultra-high performance liquid chromatography: The importance of frictional heating ⬇️

artículo científico publicado el 9 de septiembre de 2011

Prediction of retention time in reversed-phase liquid chromatography as a tool for steroid identification.

artículo científico publicado en 2016

Predictive elution window stretching and shifting as a generic search strategy for automated method development for liquid chromatography

artículo científico publicado en 2012

Preparative Scale MS-Guided Isolation of Bioactive Compounds Using High-Resolution Flash Chromatography: Antifungals from Chiloscyphus polyanthos as a Case Study

artículo científico publicado en 2016

Proof of Concept To Achieve Infinite Selectivity for the Chromatographic Separation of Therapeutic Proteins

artículo científico publicado en 2019

Protocols for the analytical characterization of therapeutic monoclonal antibodies. I - Non-denaturing chromatographic techniques.

artículo científico publicado en 2017

Protocols for the analytical characterization of therapeutic monoclonal antibodies. II - Enzymatic and chemical sample preparation.

artículo científico publicado en 2017

Protocols for the analytical characterization of therapeutic monoclonal antibodies. III - Denaturing chromatographic techniques hyphenated to mass spectrometry

scientific article published on 21 August 2018

Prototype sphere-on-sphere silica particles for the separation of large biomolecules

artículo científico publicado en 2015

Quantification of 4 antidepressants and a metabolite by LC–MS for therapeutic drug monitoring

artículo científico publicado en 2011

Quantification of glucuronidated and sulfated steroids in human urine by ultra-high pressure liquid chromatography quadrupole time-of-flight mass spectrometry

scientific article published on 06 March 2011

Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography

artículo científico publicado en 2016

Rapid log P determination of natural products in crude plant extracts from UHPLC-TOF-MS profiling data – an additional parameter for dereplication and bioavailability

artículo científico publicado en 2009

Rational and Efficient Preparative Isolation of Natural Products by MPLC-UV-ELSD based on HPLC to MPLC Gradient Transfer

artículo científico publicado en 2015

Recent advances in chromatography for pharmaceutical analysis

artículo científico publicado en 2018

Recent developments in liquid chromatography--impact on qualitative and quantitative performance

artículo científico publicado en 2006

Relation between the particle size distribution and the kinetic performance of packed columns. Application to a commercial sub-2 microm particle material

artículo científico publicado en 2007

Reliability of computer-assisted method transfer between several column dimensions packed with 1.3-5μm core-shell particles and between various instruments

artículo científico publicado en 2014

Reliability of simulated robustness testing in fast liquid chromatography, using state-of-the-art column technology, instrumentation and modelling software

artículo científico publicado en 2013

Retention modeling and method development in hydrophilic interaction chromatography

artículo científico publicado en 2014

SFC-MS versus RPLC-MS for drug analysis in biological samples

artículo científico publicado en 2015

Screening of the most relevant parameters for method development in ultra-high performance hydrophilic interaction chromatography

artículo científico publicado en 2013

Selection of suitable operating conditions to minimize the gradient equilibration time in the separation of drugs by Ultra-High-Pressure Liquid Chromatography with volatile (mass spectrometry-compatible) buffers

artículo científico publicado en 2009

Separation of antibody drug conjugate species by RPLC: A generic method development approach

artículo científico publicado en 2017

Separation of substrates and closely related glucuronide metabolites using various chromatographic modes

artículo científico publicado en 2016

Some advantages of high temperature for the separation of pharmaceutical compounds with mass spectrometry detection

artículo científico publicado en 2005

Some solutions to obtain very efficient separations in isocratic and gradient modes using small particles size and ultra-high pressure

artículo científico publicado en 2009

State-of-the art of (UHP)LC-MS(-MS) techniques and their practical application

artículo científico publicado en 2013

Streamlined Characterization of an Antibody-Drug Conjugate by Two-Dimensional and Four-Dimensional Liquid Chromatography/Mass Spectrometry

artículo científico publicado en 2019

Supercritical fluid chromatography - Mass spectrometry in metabolomics: Past, present, and future perspectives

artículo científico publicado en 2020

Supercritical fluid chromatography in pharmaceutical analysis.

artículo científico

Supercritical fluid chromatography-mass spectrometry in routine anti-doping analyses: Estimation of retention time variability under reproducible conditions

artículo científico publicado en 2019

Systematic comparison of a new generation of columns packed with sub-2 μm superficially porous particles

artículo científico publicado en 2014

Systematic comparison of sensitivity between hydrophilic interaction liquid chromatography and reversed phase liquid chromatography coupled with mass spectrometry

artículo científico publicado en 2013

Systematic evaluation of matrix effects in hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry

artículo científico publicado en 2015

Systematic evaluation of matrix effects in supercritical fluid chromatography versus liquid chromatography coupled to mass spectrometry for biological samples

artículo científico publicado en 2018

Systematic evaluation of mobile phase additives for the LC-MS characterization of therapeutic proteins

artículo científico publicado en 2015

Targeted bottom-up characterization of recombinant monoclonal antibodies by multi-dimensional LC/MS

artículo científico publicado en 2020

The Emergence of Universal Chromatographic Methods in the Research and Development of New Drug Substances

artículo científico publicado en 2019

The effect of pressure and mobile phase velocity on the retention properties of small analytes and large biomolecules in ultra-high pressure liquid chromatography

artículo científico publicado en 2012

The importance of system band broadening in modern size exclusion chromatography

artículo científico publicado en 2016

The use of columns packed with sub-2 µm particles in supercritical fluid chromatography

artículo científico publicado en 2014

Theory and practice of size exclusion chromatography for the analysis of protein aggregates

artículo científico publicado en 2014

Therapeutic Fc-fusion proteins: Current analytical strategies

scientific article published on 11 September 2020

Therapeutic drug monitoring of seven psychotropic drugs and four metabolites in human plasma by HPLC-MS.

artículo científico publicado en 2009

Trapping‐Enrichment Multi‐dimensional Liquid Chromatography with On‐Line Deuterated Solvent Exchange for Streamlined Structure Elucidation at the Microgram Scale

Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 1: Alternative mobile phases and fine tuning of the separation

scientific article published on 19 February 2019

Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 2: Evaluation of recent stationary phases

scientific article published on 05 May 2019

UHPLC determination of catechins for the quality control of green tea.

artículo científico publicado en 2013

UPLC-TOF-MS for plant metabolomics: a sequential approach for wound marker analysis in Arabidopsis thaliana

artículo científico publicado en 2008

Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. I: Investigation of mobile phase and MS conditions

artículo científico publicado en 2014

Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. II: Analysis of biological samples.

artículo científico publicado en 2014

Ultra high pressure liquid chromatography for crude plant extract profiling

artículo científico publicado el 1 de enero de 2011

Ultra-high performance supercritical fluid chromatography coupled with quadrupole-time-of-flight mass spectrometry as a performing tool for bioactive analysis.

artículo científico publicado en 2016

Unraveling the mysteries of modern size exclusion chromatography - the way to achieve confident characterization of therapeutic proteins

artículo científico publicado en 2018

Use of Ultra-short Columns for Therapeutic Protein Separations, Part 2: Designing the Optimal Column Dimension for Reversed-Phase Liquid Chromatography

artículo científico publicado en 2020

Use of Ultrashort Columns for Therapeutic Protein Separations. Part 1: Theoretical Considerations and Proof of Concept

artículo científico publicado en 2020

Use of individual retention modeling for gradient optimization in hydrophilic interaction chromatography: separation of nucleobases and nucleosides

artículo científico publicado en 2014

Utility of a high coverage phenyl-bonding and wide-pore superficially porous particle for the analysis of monoclonal antibodies and related products

artículo científico publicado en 2018

Utility of dry load injection for an efficient natural products isolation at the semi-preparative chromatographic scale

artículo científico publicado en 2019

Validation of an ultra-fast UPLC-UV method for the separation of antituberculosis tablets

artículo científico publicado en 2008

Validation of chiral capillary electrophoresis-electrospray ionization-mass spectrometry methods for ecstasy and methadone in plasma

artículo científico publicado en 2008

What are the current solutions for interfacing supercritical fluid chromatography and mass spectrometry?

artículo científico publicado en 2018

[Biosimilar monoclonal antibodies: comparative study of analytical and functional quality]

scientific article published on 01 December 2019

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