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Lista de obras de Javier A Menendez

A 2-D-HPLC-CE platform coupled to ESI-TOF-MS to characterize the phenolic fraction in olive oil

artículo científico publicado en 2009

A comparison of non-biologically active truncated EGF (EGFt) and full-length hEGF for delivery of Auger electron-emitting 111In to EGFR-positive breast cancer cells and tumor xenografts in athymic mice.

artículo científico publicado en 2015

A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway.

artículo científico publicado en 2005

A possible role for CCR5 in the progression of atherosclerosis in HIV-infected patients: a cross-sectional study.

artículo científico publicado en 2013

AMPK-sensed cellular energy state regulates the release of extracellular Fatty Acid Synthase

artículo científico publicado en 2008

AMPK: a bona fide resident of the mitotic spindle midzone.

artículo científico publicado en 2012

ATM germline mutations in Spanish early-onset breast cancer patients negative for BRCA1/BRCA2 mutations.

artículo científico publicado en 2008

Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome

artículo científico publicado en 2016

Acquired resistance to metformin in breast cancer cells triggers transcriptome reprogramming toward a degradome-related metastatic stem-like profile

artículo científico publicado en 2014

Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells

artículo científico

Activation of the methylation cycle in cells reprogrammed into a stem cell-like state.

artículo científico publicado en 2015

AlphaVbeta3 integrin regulates heregulin (HRG)-induced cell proliferation and survival in breast cancer.

artículo científico publicado en 2005

An easy, rapid and objective mathematical method to identify fatty acid synthase (oncogenic antigen-519) modulators with potential anticancer value.

artículo científico publicado en 2008

An update of the mechanisms of resistance to EGFR-tyrosine kinase inhibitors in breast cancer: Gefitinib (Iressa) -induced changes in the expression and nucleo-cytoplasmic trafficking of HER-ligands (Review).

artículo científico publicado en 2007

Analyzing effects of extra-virgin olive oil polyphenols on breast cancer-associated fatty acid synthase protein expression using reverse-phase protein microarrays.

artículo científico publicado en 2008

Androgen-independent prostate cancer cells circumvent EGFR inhibition by overexpression of alternative HER receptors and ligands

artículo científico publicado en 2012

Anti-protozoal and anti-bacterial antibiotics that inhibit protein synthesis kill cancer subtypes enriched for stem cell-like properties

artículo científico publicado en 2015

Antibody microarray-based technology to rapidly define matrix metalloproteinase (MMP) signatures in patients undergoing resection for primary gastric carcinoma

artículo científico publicado en 2011

Antitumoral actions of the anti-obesity drug orlistat (XenicalTM) in breast cancer cells: blockade of cell cycle progression, promotion of apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene

artículo científico publicado en 2005

Assessment of extracellular matrix-related biomarkers in patients with lower extremity artery disease

artículo científico publicado en 2018

Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab

artículo científico publicado en 2009

Autophagy in stem cells

artículo científico publicado en 2013

Autophagy is an inflammation-related defensive mechanism against disease.

artículo científico publicado en 2014

Axial chirality of 4-arylpyrazolo[3,4-b]pyridines. Conformational analysis and absolute configuration

scientific article published on 07 November 2014

BRCA1 and acetyl-CoA carboxylase: the metabolic syndrome of breast cancer

artículo científico publicado en 2008

BRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells

artículo científico publicado en 2017

Basal/HER2 breast carcinomas: integrating molecular taxonomy with cancer stem cell dynamics to predict primary resistance to trastuzumab (Herceptin).

artículo científico publicado en 2012

Blockade of a key region in the extracellular domain inhibits HER2 dimerization and signaling.

artículo científico publicado en 2015

CCN1 promotes vascular endothelial growth factor secretion through αvβ 3 integrin receptors in breast cancer

artículo científico

Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas

artículo científico publicado en 2015

Characterization and quantification of phenolic compounds of extra-virgin olive oils with anticancer properties by a rapid and resolutive LC-ESI-TOF MS method.

artículo científico publicado en 2009

Circulating fatty acid synthase: an exploratory biomarker to predict efficacy of the dual HER1/HER2 tyrosine kinase inhibitor lapatinib

artículo científico publicado en 2011

Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer

artículo científico publicado en 2016

Continuous administration of polyphenols from aqueous rooibos (Aspalathus linearis) extract ameliorates dietary-induced metabolic disturbances in hyperlipidemic mice.

artículo científico publicado en 2011

Crude phenolic extracts from extra virgin olive oil circumvent de novo breast cancer resistance to HER1/HER2-targeting drugs by inducing GADD45-sensed cellular stress, G2/M arrest and hyperacetylation of Histone H3.

artículo científico publicado en 2011

Diagnostic utility of mammaglobin and GCDFP-15 in the identification of primary neuroendocrine carcinomas of the breast ⬇️

artículo científico publicado el 27 de octubre de 2010

Dietary fatty acids regulate the activation status of Her-2/neu (c-erbB-2) oncogene in breast cancer cells

scientific article published on 01 November 2004

Direct antitumour activity of zoledronic acid: preclinical and clinical data

artículo científico publicado en 2011

Direct characterization of aqueous extract of Hibiscus sabdariffa using HPLC with diode array detection coupled to ESI and ion trap MS.

artículo científico publicado en 2009

Discordant expression of molecular markers between primary and nodal metastases: a histopathological manifestation of the 'self (stem cell)-seeding' nature of breast cancer disease?

scientific article published on 23 December 2009

Dynamic emergence of the mesenchymal CD44(pos)CD24(neg/low) phenotype in HER2-gene amplified breast cancer cells with de novo resistance to trastuzumab (Herceptin).

artículo científico publicado en 2010

Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene.

artículo científico publicado en 2005

Effects of gamma-linolenic acid and oleic acid on paclitaxel cytotoxicity in human breast cancer cells

artículo científico publicado en 2001

Energy metabolism and metabolic sensors in stem cells: the metabostem crossroads of aging and cancer

artículo científico publicado en 2014

EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells

artículo científico publicado en 2017

Epigenetic regulation of cell fate reprogramming in aging and disease: A predictive computational model.

artículo científico publicado en 2018

Epigenetics and nutrition-related epidemics of metabolic diseases: Current perspectives and challenges

artículo científico publicado en 2016

Epithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin).

artículo científico publicado en 2012

Evolution of the predictive markers amphiregulin and epiregulin mRNAs during long-term cetuximab treatment of KRAS wild-type tumor cells

artículo científico publicado en 2010

Exploring the Process of Energy Generation in Pathophysiology by Targeted Metabolomics: Performance of a Simple and Quantitative Method.

artículo científico publicado en 2015

Expression status of the autophagy-regulatory gene ATG6/BECN1 in ERBB2-positive breast carcinomas: bypassing ERBB2-induced oncogenic senescence to regulate the efficacy of ERBB2-targeted therapies

artículo científico publicado en 2011

Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells

artículo científico publicado en 2018

Extracellular fatty acid synthase: a possible surrogate biomarker of insulin resistance ⬇️

artículo científico publicado en 2010

Fatty Acid Synthase Is a Key Enabler for Endocrine Resistance in Heregulin-Overexpressing Luminal B-Like Breast Cancer

artículo científico publicado en 2020

Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75.

artículo científico publicado en 2007

Fatty acid synthase (FASN) as a therapeutic target in breast cancer.

artículo científico publicado en 2017

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

artículo científico publicado en 2007

Fatty acid synthase regulates estrogen receptor-α signaling in breast cancer cells.

artículo científico publicado en 2017

Fine-tuning the lipogenic/lipolytic balance to optimize the metabolic requirements of cancer cell growth: molecular mechanisms and therapeutic perspectives.

artículo científico publicado en 2009

Genome-wide inhibitory impact of the AMPK activator metformin on [kinesins, tubulins, histones, auroras and polo-like kinases] M-phase cell cycle genes in human breast cancer cells.

artículo científico publicado en 2009

Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.

scientific article published on 31 May 2016

Gerometabolites: the pseudohypoxic aging side of cancer oncometabolites.

artículo científico publicado en 2014

Giacomo Castelvetro's salads. Anti-HER2 oncogene nutraceuticals since the 17th century?

artículo científico publicado en 2008

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Her-2/neu-induced "cytokine signature" in breast cancer.

artículo científico publicado en 2008

Heregulin Drives Endocrine Resistance by Altering IL-8 Expression in ER-Positive Breast Cancer

artículo científico publicado en 2020

Heregulin, a new interactor of the telosome/shelterin complex in human telomeres.

artículo científico publicado en 2015

Heregulin, a new regulator of telomere length in human cells

artículo científico publicado en 2015

Hibiscus sabdariffaextract lowers blood pressure and improves endothelial function

scientific article published on 24 February 2014

IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations

artículo científico publicado en 2013

Identification of active compounds in vegetal extracts based on correlation between activity and HPLC-MS data.

artículo científico publicado en 2012

Incorporating the antidiabetic drug metformin in HER2-positive breast cancer treated with neo-adjuvant chemotherapy and trastuzumab: an ongoing clinical-translational research experience at the Catalan Institute of Oncology.

artículo científico publicado en 2009

Infection with HIV and HCV enhances the release of fatty acid synthase into circulation: evidence for a novel indicator of viral infection

artículo científico publicado en 2010

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

artículo científico publicado en 2004

Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis.

artículo científico publicado en 2005

Inhibition of tumor-associated fatty acid synthase activity enhances vinorelbine (Navelbine)-induced cytotoxicity and apoptotic cell death in human breast cancer cells.

artículo científico publicado en 2004

Inhibition of tumor-associated fatty acid synthase hyperactivity induces synergistic chemosensitization of HER -2/ neu -overexpressing human breast cancer cells to docetaxel (taxotere).

artículo científico publicado en 2004

Inhibitor of Apoptosis (IAP) survivin is indispensable for survival of HER2 gene-amplified breast cancer cells with primary resistance to HER1/2-targeted therapies

article

Interferon/STAT1 and neuregulin signaling pathways are exploratory biomarkers of cetuximab (Erbitux®) efficacy in KRAS wild-type squamous carcinomas: a pathway-based analysis of whole human-genome microarray data from cetuximab-adapted tumor cell-li

artículo científico publicado en 2011

Intestinal Permeability Study of Clinically Relevant Formulations of Silibinin in Caco-2 Cell Monolayers ⬇️

artículo científico

Lemon verbena (Lippia citriodora) polyphenols alleviate obesity-related disturbances in hypertrophic adipocytes through AMPK-dependent mechanisms.

artículo científico publicado en 2015

Liver fat deposition and mitochondrial dysfunction in morbid obesity: An approach combining metabolomics with liver imaging and histology

artículo científico publicado en 2015

Low-scale phosphoproteome analyses identify the mTOR effector p70 S6 kinase 1 as a specific biomarker of the dual-HER1/HER2 tyrosine kinase inhibitor lapatinib (Tykerb) in human breast carcinoma cells.

artículo científico publicado en 2008

Mammosphere formation in breast carcinoma cell lines depends upon expression of E-cadherin

artículo científico publicado en 2013

Managing hypertension by polyphenols.

artículo científico publicado en 2015

Mapping of the circulating metabolome reveals α-ketoglutarate as a predictor of morbid obesity-associated non-alcoholic fatty liver disease

artículo científico publicado en 2014

Mediterranean diet, olive oil and cancer.

artículo científico publicado en 2006

Metabolic control of cancer cell stemness: Lessons from iPS cells

artículo científico publicado en 2015

Metabolic stress in infected cells may represent a therapeutic target for human immunodeficiency virus infection.

artículo científico publicado en 2013

Metabolomic mapping of cancer stem cells for reducing and exploiting tumor heterogeneity

artículo científico publicado en 2017

Metabostemness: Metaboloepigenetic reprogramming of cancer stem-cell functions

artículo científico publicado en 2014

Metabostemness: a new cancer hallmark.

artículo científico publicado en 2014

Metformin Potentiates the Benefits of Dietary Restraint: A Metabolomic Study.

artículo científico publicado en 2017

Metformin activates an ataxia telangiectasia mutated (ATM)/Chk2-regulated DNA damage-like response

artículo científico publicado en 2011

Metformin against TGFβ-induced epithelial-to-mesenchymal transition (EMT): from cancer stem cells to aging-associated fibrosis.

artículo científico publicado en 2010

Metformin and energy metabolism in breast cancer: from insulin physiology to tumour-initiating stem cells.

artículo científico publicado en 2010

Metformin directly targets the H3K27me3 demethylase KDM6A/UTX

scientific article published on 08 May 2018

Metformin inhibits RANKL and sensitizes cancer stem cells to denosumab

artículo científico publicado en 2017

Metformin is synthetically lethal with glucose withdrawal in cancer cells.

artículo científico publicado en 2012

Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism.

artículo científico publicado en 2017

Metformin targets histone acetylation in cancer-prone epithelial cells

artículo científico publicado en 2016

Metformin: a cheap and well-tolerated drug that provides benefits for viral infections.

artículo científico publicado en 2012

Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFβ-induced oncomiR miRNA-181a ⬇️

artículo científico publicado el 1 de abril de 2011

Mitochondrial dysfunction: a basic mechanism in inflammation-related non-communicable diseases and therapeutic opportunities

artículo científico

Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate

scientific article published on 13 June 2016

Mitostemness

artículo científico publicado en 2018

Molecular promiscuity of plant polyphenols in the management of age-related diseases: far beyond their antioxidant properties

artículo científico

Neoadjuvant Metformin Added to Systemic Therapy Decreases the Proliferative Capacity of Residual Breast Cancer

artículo científico publicado en 2019

Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.

artículo científico publicado en 2004

Nuclear reprogramming of cancer stem cells: Corrupting the epigenetic code of cell identity with oncometabolites

artículo científico publicado en 2016

Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway

artículo científico publicado en 2013

Nutrients in Energy and One-Carbon Metabolism: Learning from Metformin Users.

artículo científico publicado en 2017

Nutritional Niches of Cancer Therapy-Induced Senescent Cells

scientific article published in 2022

Obesity, fatty acid synthase, and cancer: serendipity or forgotten causal linkage?

artículo científico publicado en 2004

Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin) in HER2-overexpressing breast cancer cells.

artículo científico publicado en 2007

Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) enhances docetaxel (Taxotere) cytotoxicity in human breast carcinoma cells: Relationship to lipid peroxidation and HER-2/neu expression.

artículo científico publicado en 2004

Oncogenic properties of the endogenous fatty acid metabolism: molecular pathology of fatty acid synthase in cancer cells.

artículo científico publicado en 2006

Oncometabolic Nuclear Reprogramming of Cancer Stemness

artículo científico publicado en 2016

Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype.

artículo científico publicado en 2015

Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-li

artículo científico publicado en 2004

Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells

artículo científico publicado en 2008

Pediatric solid organ transplant recipients: transition to home and chronic illness care

artículo científico publicado en 2014

Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/neu (erbB-2) oncogene-induced malignant transformation.

artículo científico publicado en 2004

Pharmacological mimicking of caloric restriction elicits epigenetic reprogramming of differentiated cells to stem-like self-renewal states.

artículo científico publicado en 2010

Phenolic secoiridoids in extra virgin olive oil impede fibrogenic and oncogenic epithelial-to-mesenchymal transition: extra virgin olive oil as a source of novel antiaging phytochemicals.

artículo científico publicado en 2012

Plant-derived polyphenols regulate expression of miRNA paralogs miR-103/107 and miR-122 and prevent diet-induced fatty liver disease in hyperlipidemic mice

artículo científico publicado en 2012

Plasma Energy-Balance Metabolites Discriminate Asymptomatic Patients with Peripheral Artery Disease

scientific article published on 20 September 2018

Polo-like kinase 1 directs the AMPK-mediated activation of myosin regulatory light chain at the cytokinetic cleavage furrow independently of energy balance

artículo científico publicado en 2012

Polo-like kinase 1 regulates activation of AMP-activated protein kinase (AMPK) at the mitotic apparatus.

artículo científico publicado en 2011

Polyphenols and the modulation of gene expression pathways: can we eat our way out of the danger of chronic disease?

artículo científico publicado en 2014

Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2'-O-Methylation of Viral RNA

scientific article published on 10 May 2020

Prediction of extra virgin olive oil varieties through their phenolic profile. Potential cytotoxic activity against human breast cancer cells.

artículo científico publicado en 2010

Pro-Oxidant Activity of Amine-Pyridine-Based Iron Complexes Efficiently Kills Cancer and Cancer Stem-Like Cells

artículo científico publicado en 2015

Protein array technology to detect HER2 (erbB-2)-induced 'cytokine signature' in breast cancer.

artículo científico publicado en 2007

Raptor, a positive regulatory subunit of mTOR complex 1, is a novel phosphoprotein of the rDNA transcription machinery in nucleoli and chromosomal nucleolus organizer regions (NORs)

scientific article published on 15 September 2011

Rejuvenating regeneration: metformin activates endogenous adult stem cells.

artículo científico publicado en 2012

Repositioning chloroquine and metformin to eliminate cancer stem cell traits in pre-malignant lesions

artículo científico publicado en 2011

Reprogramming of non-genomic estrogen signaling by the stemness factor SOX2 enhances the tumor-initiating capacity of breast cancer cells

artículo científico publicado en 2013

Response of brain metastasis from lung cancer patients to an oral nutraceutical product containing silibinin

artículo científico publicado en 2016

STAT3-targeted treatment with silibinin overcomes the acquired resistance to crizotinib in ALK-rearranged lung cancer

artículo científico publicado en 2016

Senescence-Inflammatory Regulation of Reparative Cellular Reprogramming in Aging and Cancer.

artículo científico publicado en 2017

Serine79-phosphorylated acetyl-CoA carboxylase, a downstream target of AMPK, localizes to the mitotic spindle poles and the cytokinesis furrow.

artículo científico publicado en 2013

Serum HER-2 concentration is associated with insulin resistance and decreases after weight loss.

artículo científico publicado en 2010

Serum concentrations of extracellular fatty acid synthase in patients with steatohepatitis

artículo científico publicado en 2009

Serum fatty acid synthase concentration is increased in patients with hepatitis viral infection and may assist in the prediction of liver steatosis

scientific article published on 08 May 2011

Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients

artículo científico publicado en 2020

Silibinin and STAT3: A natural way of targeting transcription factors for cancer therapy

artículo científico publicado en 2015

Silibinin is a direct inhibitor of STAT3.

artículo científico publicado en 2018

Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells

artículo científico publicado en 2013

Silibinin suppresses EMT-driven erlotinib resistance by reversing the high miR-21/low miR-200c signature in vivo

scientific article published on January 2013

Stem cell property epithelial-to-mesenchymal transition is a core transcriptional network for predicting cetuximab (Erbitux™) efficacy in KRAS wild-type tumor cells

artículo científico publicado en 2011

Stem cell-like ALDH(bright) cellular states in EGFR-mutant non-small cell lung cancer: a novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin

artículo científico publicado en 2013

Structure-Biological Activity Relationships of Extra-Virgin Olive Oil Phenolic Compounds: Health Properties and Bioavailability

artículo científico publicado en 2020

Successful empirical erlotinib treatment of a mechanically ventilated patient newly diagnosed with metastatic lung adenocarcinoma

artículo científico publicado en 2014

Suppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer.

artículo científico publicado en 2016

Synchronous solid neuroendocrine breast carcinoma and abdominal lymphoma: A case report and review of the literature ⬇️

artículo científico publicado el 23 de noviembre de 2012

Synthetic lethal interaction of cetuximab with MEK1/2 inhibition in NRAS-mutant metastatic colorectal cancer

artículo científico publicado en 2016

Targeting STAT3 with silibinin to improve cancer therapeutics

artículo científico publicado en 2017

Targeting fatty acid synthase-driven lipid rafts: a novel strategy to overcome trastuzumab resistance in breast cancer cells.

artículo científico publicado en 2005

Targeting human epidermal growth factor receptor 2: it is time to kill kinase death human epidermal growth factor receptor 3

artículo científico publicado en 2007

Tentative characterization of novel phenolic compounds in extra virgin olive oils by rapid-resolution liquid chromatography coupled with mass spectrometry.

artículo científico publicado en 2009

Testing the efficacy of antiangiogenic agents in advanced neuroendocrine tumors

scientific article published on 01 June 2007

The Activation of the Sox2 RR2 Pluripotency Transcriptional Reporter in Human Breast Cancer Cell Lines is Dynamic and Labels Cells with Higher Tumorigenic Potential

artículo científico publicado en 2014

The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells

artículo científico publicado en 2013

The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis.

artículo científico publicado en 2009

The acute impact of polyphenols from Hibiscus sabdariffa in metabolic homeostasis: an approach combining metabolomics and gene-expression analyses

artículo científico publicado en 2015

The angiogenic factor CYR61 in breast cancer: molecular pathology and therapeutic perspectives.

artículo científico publicado en 2003

The anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancer

artículo científico publicado en 2013

The antiobesity drug Orlistat induces cytotoxic effects, suppresses Her-2/neu (erbB-2) oncogene overexpression, and synergistically interacts with trastuzumab (Herceptin) in chemoresistant ovarian cancer cells.

artículo científico publicado en 2006

The estrogenic activity of synthetic progestins used in oral contraceptives enhances fatty acid synthase-dependent breast cancer cell proliferation and survival.

artículo científico publicado en 2005

The metastasis inducer CCN1 (CYR61) activates the fatty acid synthase (FASN)-driven lipogenic phenotype in breast cancer cells

artículo científico publicado en 2016

The promiscuous and synergic molecular interaction of polyphenols in bactericidal activity: an opportunity to improve the performance of antibiotics?

artículo científico publicado en 2015

Transcriptional upregulation of HER2 expression in the absence of HER2 gene amplification results in cetuximab resistance that is reversed by trastuzumab treatment.

artículo científico publicado en 2012

Transphosphorylation of kinase-dead HER3 and breast cancer progression: a new standpoint or an old concept revisited?

artículo científico publicado en 2007

Trastuzumab plus tamoxifen: anti-proliferative and molecular interactions in breast carcinoma.

artículo científico publicado en 2004

Tumor Cell-Intrinsic Immunometabolism and Precision Nutrition in Cancer Immunotherapy

artículo científico publicado en 2020

Ubiquitous transgenic overexpression of C-C chemokine ligand 2: a model to assess the combined effect of high energy intake and continuous low-grade inflammation.

artículo científico publicado en 2013

Understanding the role of circulating chemokine (C-C motif) ligand 2 in patients with chronic ischemia threatening the lower extremities

artículo científico publicado en 2014

Uptake and metabolism of olive oil polyphenols in human breast cancer cells using nano-liquid chromatography coupled to electrospray ionization–time of flight-mass spectrometry ⬇️

artículo científico publicado el 25 de abril de 2012

Why does tumor-associated fatty acid synthase (oncogenic antigen-519) ignore dietary fatty acids?

artículo científico publicado en 2005

Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents

artículo científico publicado en 2013

Xenopatients 2.0: reprogramming the epigenetic landscapes of patient-derived cancer genomes

artículo científico publicado en 2014

mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging

artículo científico publicado en 2011

tabAnti-HER2 (erbB-2) oncogene effects of phenolic compounds directly isolated from commercial Extra-Virgin Olive Oil (EVOO)

artículo científico publicado en 2008

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Infección por el virus de la inmunodeficiencia humana como modelo de envejecimiento prematuro: perspectivas e implicaciones ⬇️

artículo científico publicado el 16 de marzo de 2012

Recommendations of the Spanish Brachytherapy Group of SEOR for HDR endoluminal treatments. Part 1: Oesophagus

artículo científico publicado en 2015

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