Lista de obras - Juan Carlos Morales Sánchez

A Photoresponsive Stiff-Stilbene Ligand Fuels the Reversible Unfolding of G-Quadruplex DNA.

artículo científico publicado en 2019

A concise synthesis of glucuronide metabolites of urolithin-B, resveratrol, and hydroxytyrosol.

artículo científico publicado en 2009

A highly effective nonpolar isostere of deoxyguanosine: synthesis, structure, stacking, and base pairing

artículo científico publicado en 2002

Alkylated resveratrol prodrugs and metabolites as potential therapeutics for neurodegenerative diseases.

artículo científico publicado en 2018

Antioxidant activity of alkyl gallates and glycosyl alkyl gallates in fish oil in water emulsions: relevance of their surface active properties and of the type of emulsifier

artículo científico publicado en 2015

Antioxidant activity of resveratrol in several fish lipid matrices: effect of acylation and glucosylation.

artículo científico publicado en 2010

Apolar carbohydrates as DNA capping agents

artículo científico publicado en 2012

Binding and Beyond: What Else Can G-Quadruplex Ligands Do?

artículo científico publicado en 2019

Carbohydrate-DNA interactions at G-quadruplexes: folding and stability changes by attaching sugars at the 5'-end

artículo científico publicado en 2013

Carbohydrate-naphthalene diimide conjugates as potential antiparasitic drugs: Synthesis, evaluation and structure-activity studies

scientific article published on 19 November 2018

Chemically Tuning Resveratrol for the Effective Killing of Gram-Positive Pathogens

artículo científico publicado en 2022

Cytotoxic, Antiangiogenic and Antitelomerase Activity of Glucosyl- and Acyl- Resveratrol Prodrugs and Resveratrol Sulfate Metabolites.

artículo científico publicado en 2016

Divalent Naphthalene Diimide Ligands Display High Selectivity for the Human Telomeric G-quadruplex in K+ Buffer

artículo científico publicado en 2017

Effect of lipophilization of hydroxytyrosol on its antioxidant activity in fish oils and fish oil-in-water emulsions.

artículo científico publicado en 2009

Effects of long-term consumption of low doses of resveratrol on diet-induced mild hypercholesterolemia in pigs: a transcriptomic approach to disease prevention.

artículo científico publicado en 2011

Effects of sugar functional groups, hydrophobicity, and fluorination on carbohydrate-DNA stacking interactions in water.

artículo científico publicado en 2014

Efficient replication between non-hydrogen-bonded nucleoside shape analogs

scientific article published on 01 November 1998

Enhanced sampling molecular dynamics simulations correctly predict the diverse activities of a series of stiff-stilbene G-quadruplex DNA ligands

artículo científico publicado en 2021

Enzymatic Synthesis of a Novel Neuroprotective Hydroxytyrosyl Glycoside.

artículo científico publicado en 2017

Enzymatic Synthesis of a Novel Pterostilbene α-Glucoside by the Combination of Cyclodextrin Glucanotransferase and Amyloglucosidase.

artículo científico publicado en 2018

Experimental measurement of carbohydrate-aromatic stacking in water by using a dangling-ended DNA model system

artículo científico publicado en 2008

G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents.

artículo científico publicado en 2018

Glucose conjugation of anti-HIV-1 oligonucleotides containing unmethylated CpG motifs reduces their immunostimulatory activity

artículo científico publicado en 2015

Glucose-Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA

artículo científico publicado en 2016

Glucose-nucleobase pairs within DNA: impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies.

artículo científico publicado en 2018

Hemolytic activity and solubilizing capacity of raffinose and melezitose fatty acid monoesters prepared by enzymatic synthesis

artículo científico publicado en 2015

High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds.

artículo científico publicado en 2003

High-level expression and characterization of Galactomyces geotrichum (BT107) lipase I in Pichia pastoris

artículo científico publicado en 2006

Highly Polar Carbohydrates Stack onto DNA Duplexes via CH/π Interactions

scientific article published on 18 January 2011

Hydroxytyrosol and tyrosol sulfate metabolites protect against the oxidized cholesterol pro-oxidant effect in Caco-2 human enterocyte-like cells

artículo científico publicado en 2016

Hydroxytyrosol glucuronides protect renal tubular epithelial cells against H(2)O(2) induced oxidative damage.

artículo científico publicado en 2011

Imide Condensation as a Strategy for the Synthesis of Core‐Diversified G‐Quadruplex Ligands with Anticancer and Antiparasitic Activity

artículo científico publicado en 2021

Importance of terminal base pair hydrogen-bonding in 3'-end proofreading by the Klenow fragment of DNA polymerase I

artículo científico publicado en 2000

Improved sample treatment for the determination of fructooligosaccharides in milk related products by liquid chromatography with electrochemical and refractive index detection

artículo científico publicado en 2015

Kinetics and binding of the thymine-DNA mismatch glycosylase, Mig-Mth, with mismatch-containing DNA substrates

artículo científico publicado en 2003

Metabolites and tissue distribution of resveratrol in the pig

artículo científico publicado en 2011

Minor Groove Interactions between Polymerase and DNA: More Essential to Replication than Watson−Crick Hydrogen Bonds? ⬇️

artículo científico publicado el 14 de febrero de 1999

Neuroprotective and Anti-inflammatory Effects of Pterostilbene Metabolites in Human Neuroblastoma SH-SY5Y and RAW 264.7 Macrophage Cells

scientific article published on 29 January 2020

Non-reducing trisaccharide fatty acid monoesters: Novel detergents in membrane biochemistry

artículo científico publicado en 2010

Parallel-stranded hairpins containing 8-aminopurines. Novel efficient probes for triple-helix formation.

artículo científico publicado en 2001

Positive-ion ESI mass spectrometry of regioisomeric nonreducing oligosaccharide fatty acid monoesters: in-source fragmentation of sodium adducts.

artículo científico publicado en 2008

Properties of Triple Helices Formed by Oligonucleotides Containing 8-Aminopurines

artículo científico publicado en 2003

Properties of triple helices formed by parallel-stranded hairpins containing 8-aminopurines.

artículo científico publicado en 2002

Resveratrol and some glucosyl, glucosylacyl, and glucuronide derivatives reduce Escherichia coli O157:H7, Salmonella Typhimurium, and Listeria monocytogenes Scott A adhesion to colonic epithelial cell lines

artículo científico publicado en 2012

Significance of nucleobase shape complementarity and hydrogen bonding in the formation and stability of the closed polymerase-DNA complex

artículo científico publicado en 2001

Simultaneous determination of eight water-soluble vitamins in supplemented foods by liquid chromatography

artículo científico publicado en 2006

Skin delivery of antioxidant surfactants based on gallic acid and hydroxytyrosol

artículo científico publicado en 2015

Stiff-Stilbene Ligands Target G-Quadruplex DNA and Exhibit Selective Anticancer and Antiparasitic Activity

artículo científico publicado en 2020

Structure and Base Pairing Properties of a Replicable Nonpolar Isostere for Deoxyadenosine

artículo científico publicado en 1998

Surface-Active Properties of Lipophilic Antioxidants Tyrosol and Hydroxytyrosol Fatty Acid Esters: A Potential Explanation for the Nonlinear Hypothesis of the Antioxidant Activity in Oil-in-Water Emulsions

artículo científico publicado en 2010

Synthesis and Biophysical Investigations of Oligonucleotides Containing Galactose-Modified DNA, LNA, and 2'-Amino-LNA Monomers

artículo científico publicado en 2016

Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations ⬇️

artículo científico publicado el 26 de enero de 2011

Synthesis, Binding Properties, and Differences in Cell Uptake of G-Quadruplex Ligands Based on Carbohydrate Naphthalene Diimide Conjugates.

artículo científico publicado en 2016

Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates

artículo científico publicado en 2013

Synthesis, cell-surface binding, and cellular uptake of fluorescently labeled glucose-DNA conjugates with different carbohydrate presentation.

artículo científico publicado en 2010

The effect of l-thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures

artículo científico publicado en 2016

The gut microbiota ellagic acid-derived metabolite urolithin A and its sulfate conjugate are substrates for the drug efflux transporter breast cancer resistance protein (ABCG2/BCRP).

artículo científico publicado en 2013

Tyrosol and hydroxytyrosol derivatives as antitrypanosomal and antileishmanial agents

artículo científico publicado en 2016

Tyrosol and its metabolites as antioxidative and anti-inflammatory molecules in human endothelial cells.

artículo científico publicado en 2017

Visible-light photoswitching of ligand binding mode suggests G-quadruplex DNA as a target for photopharmacology

scientific article published on 08 April 2020

Lista de obras de Juan Carlos Morales Sánchez

A Photoresponsive Stiff-Stilbene Ligand Fuels the Reversible Unfolding of G-Quadruplex DNA.

A concise synthesis of glucuronide metabolites of urolithin-B, resveratrol, and hydroxytyrosol.

A highly effective nonpolar isostere of deoxyguanosine: synthesis, structure, stacking, and base pairing

Alkylated resveratrol prodrugs and metabolites as potential therapeutics for neurodegenerative diseases.

Antioxidant activity of alkyl gallates and glycosyl alkyl gallates in fish oil in water emulsions: relevance of their surface active properties and of the type of emulsifier

Antioxidant activity of resveratrol in several fish lipid matrices: effect of acylation and glucosylation.

Apolar carbohydrates as DNA capping agents

Binding and Beyond: What Else Can G-Quadruplex Ligands Do?

Carbohydrate-DNA interactions at G-quadruplexes: folding and stability changes by attaching sugars at the 5'-end

Carbohydrate-naphthalene diimide conjugates as potential antiparasitic drugs: Synthesis, evaluation and structure-activity studies

Chemically Tuning Resveratrol for the Effective Killing of Gram-Positive Pathogens

Cytotoxic, Antiangiogenic and Antitelomerase Activity of Glucosyl- and Acyl- Resveratrol Prodrugs and Resveratrol Sulfate Metabolites.

Divalent Naphthalene Diimide Ligands Display High Selectivity for the Human Telomeric G-quadruplex in K+ Buffer

Effect of lipophilization of hydroxytyrosol on its antioxidant activity in fish oils and fish oil-in-water emulsions.

Effects of long-term consumption of low doses of resveratrol on diet-induced mild hypercholesterolemia in pigs: a transcriptomic approach to disease prevention.

Effects of sugar functional groups, hydrophobicity, and fluorination on carbohydrate-DNA stacking interactions in water.

Efficient replication between non-hydrogen-bonded nucleoside shape analogs

Enhanced sampling molecular dynamics simulations correctly predict the diverse activities of a series of stiff-stilbene G-quadruplex DNA ligands

Enzymatic Synthesis of a Novel Neuroprotective Hydroxytyrosyl Glycoside.

Enzymatic Synthesis of a Novel Pterostilbene α-Glucoside by the Combination of Cyclodextrin Glucanotransferase and Amyloglucosidase.

Experimental measurement of carbohydrate-aromatic stacking in water by using a dangling-ended DNA model system

G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents.

Glucose conjugation of anti-HIV-1 oligonucleotides containing unmethylated CpG motifs reduces their immunostimulatory activity

Glucose-Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA

Glucose-nucleobase pairs within DNA: impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies.

Hemolytic activity and solubilizing capacity of raffinose and melezitose fatty acid monoesters prepared by enzymatic synthesis

High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds.

High-level expression and characterization of Galactomyces geotrichum (BT107) lipase I in Pichia pastoris

Highly Polar Carbohydrates Stack onto DNA Duplexes via CH/π Interactions

Hydroxytyrosol and tyrosol sulfate metabolites protect against the oxidized cholesterol pro-oxidant effect in Caco-2 human enterocyte-like cells

Hydroxytyrosol glucuronides protect renal tubular epithelial cells against H(2)O(2) induced oxidative damage.

Imide Condensation as a Strategy for the Synthesis of Core‐Diversified G‐Quadruplex Ligands with Anticancer and Antiparasitic Activity

Importance of terminal base pair hydrogen-bonding in 3'-end proofreading by the Klenow fragment of DNA polymerase I

Improved sample treatment for the determination of fructooligosaccharides in milk related products by liquid chromatography with electrochemical and refractive index detection

Kinetics and binding of the thymine-DNA mismatch glycosylase, Mig-Mth, with mismatch-containing DNA substrates

Metabolites and tissue distribution of resveratrol in the pig

Minor Groove Interactions between Polymerase and DNA: More Essential to Replication than Watson−Crick Hydrogen Bonds? ⬇️

Neuroprotective and Anti-inflammatory Effects of Pterostilbene Metabolites in Human Neuroblastoma SH-SY5Y and RAW 264.7 Macrophage Cells

Non-reducing trisaccharide fatty acid monoesters: Novel detergents in membrane biochemistry

Parallel-stranded hairpins containing 8-aminopurines. Novel efficient probes for triple-helix formation.

Positive-ion ESI mass spectrometry of regioisomeric nonreducing oligosaccharide fatty acid monoesters: in-source fragmentation of sodium adducts.

Properties of Triple Helices Formed by Oligonucleotides Containing 8-Aminopurines

Properties of triple helices formed by parallel-stranded hairpins containing 8-aminopurines.

Resveratrol and some glucosyl, glucosylacyl, and glucuronide derivatives reduce Escherichia coli O157:H7, Salmonella Typhimurium, and Listeria monocytogenes Scott A adhesion to colonic epithelial cell lines

Significance of nucleobase shape complementarity and hydrogen bonding in the formation and stability of the closed polymerase-DNA complex

Simultaneous determination of eight water-soluble vitamins in supplemented foods by liquid chromatography

Skin delivery of antioxidant surfactants based on gallic acid and hydroxytyrosol

Stiff-Stilbene Ligands Target G-Quadruplex DNA and Exhibit Selective Anticancer and Antiparasitic Activity

Structure and Base Pairing Properties of a Replicable Nonpolar Isostere for Deoxyadenosine

Surface-Active Properties of Lipophilic Antioxidants Tyrosol and Hydroxytyrosol Fatty Acid Esters: A Potential Explanation for the Nonlinear Hypothesis of the Antioxidant Activity in Oil-in-Water Emulsions

Synthesis and Biophysical Investigations of Oligonucleotides Containing Galactose-Modified DNA, LNA, and 2'-Amino-LNA Monomers

Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations ⬇️

Synthesis, Binding Properties, and Differences in Cell Uptake of G-Quadruplex Ligands Based on Carbohydrate Naphthalene Diimide Conjugates.

Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates

Synthesis, cell-surface binding, and cellular uptake of fluorescently labeled glucose-DNA conjugates with different carbohydrate presentation.

The effect of l-thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures

The gut microbiota ellagic acid-derived metabolite urolithin A and its sulfate conjugate are substrates for the drug efflux transporter breast cancer resistance protein (ABCG2/BCRP).

Tyrosol and hydroxytyrosol derivatives as antitrypanosomal and antileishmanial agents

Tyrosol and its metabolites as antioxidative and anti-inflammatory molecules in human endothelial cells.

Visible-light photoswitching of ligand binding mode suggests G-quadruplex DNA as a target for photopharmacology