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126 Creation of a Humanized Model for Respiratory Allergy Using a Human Mugwort-specificT-Cell Receptor and HLA-DR1.

artículo científico publicado en 2012

3-Layer-based analysis of peptide-MHC interaction: in silico prediction, peptide binding affinity and T cell activation in a relevant allergen-specific model.

artículo científico publicado en 2009

4-1BB costimulation promotes bystander activation of human CD8 T cells

artículo científico publicado en 2020

6th International Symposium on Molecular Allergology (ISMA).

artículo científico publicado en 2016

A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination.

artículo científico publicado en 2005

A novel approach to specific allergy treatment: the recombinant allergen-S-layer fusion protein rSbsC-Bet v 1 matures dendritic cells that prime Th0/Th1 and IL-10-producing regulatory T cells

artículo científico publicado en 2007

A novel approach to specific allergy treatment: the recombinant fusion protein of a bacterial cell surface (S-layer) protein and the major birch pollen allergen Bet v 1 (rSbsC-Bet v 1) combines reduced allergenicity with immunomodulating capacity.

artículo científico publicado en 2004

Allergens with Protease Activity from House Dust Mites

artículo científico publicado en 2017

Alum-adjuvanted allergoids induce functional IgE-blocking antibodies

artículo científico publicado en 2018

Amb a 1 isoforms: Unequal siblings with distinct immunological features.

artículo científico publicado en 2017

Antigen presentation of the immunodominant T-cell epitope of the major mugwort pollen allergen, Art v 1, is associated with the expression of HLA-DRB1 *01.

artículo científico publicado en 2005

Art v 1, the major allergen of mugwort pollen, is a modular glycoprotein with a defensin-like and a hydroxyproline-rich domain

artículo científico publicado en 2002

Association of HLA-DR1 with the allergic response to the major mugwort pollen allergen: molecular background.

artículo científico publicado en 2012

Bet v 1, the major birch pollen allergen, initiates sensitization to Api g 1, the major allergen in celery: evidence at the T cell level

artículo científico publicado en 2003

Bet v 1-specific T-cell receptor/forkhead box protein 3 transgenic T cells suppress Bet v 1-specific T-cell effector function in an activation-dependent manner.

artículo científico publicado en 2011

Bet v 1142-156 is the dominant T-cell epitope of the major birch pollen allergen and important for cross-reactivity with Bet v 1-related food allergens

artículo científico publicado en 2005

CD23 surface density on B cells is associated with IgE levels and determines IgE-facilitated allergen uptake, as well as activation of allergen-specific T cells.

artículo científico publicado en 2016

Characterization of HLA class II/peptide-TCR interactions of the immunodominant T cell epitope in Art v 1, the major mugwort pollen allergen.

artículo científico publicado en 2008

Characterization of autoreactive T cells to the autoantigens heterogeneous nuclear ribonucleoprotein A2 (RA33) and filaggrin in patients with rheumatoid arthritis

artículo científico publicado en 2002

Characterization of the allergic T-cell response to Pru p 3, the nonspecific lipid transfer protein in peach

artículo científico publicado en 2009

Combination vaccines for the treatment of grass pollen allergy consisting of genetically engineered hybrid molecules with increased immunogenicity

scientific article published on 21 June 2002

Cooking birch pollen-related food: divergent consequences for IgE- and T cell-mediated reactivity in vitro and in vivo.

artículo científico publicado en 2006

Creation of an engineered APC system to explore and optimize the presentation of immunodominant peptides of major allergens

artículo científico publicado en 2016

Distinct epitope structures of defensin-like proteins linked to proline-rich regions give rise to differences in their allergenic activity.

artículo científico publicado en 2017

Gastrointestinal digestion of Bet v 1-homologous food allergens destroys their mediator-releasing, but not T cell-activating, capacity

artículo científico publicado en 2005

Genetic restriction of antigen-presentation dictates allergic sensitization and disease in humanized mice

artículo científico publicado en 2018

Glutathione-S-transferase: a minor allergen in birch pollen due to limited release from hydrated pollen

artículo científico publicado en 2014

Human TCR transgenic Bet v 1-specific Th1 cells suppress the effector function of Bet v 1-specific Th2 cells

artículo científico publicado en 2011

Humoral and Cellular Cross-Reactivity between Amb a 1, the Major Ragweed Pollen Allergen, and Its Mugwort Homolog Art v 6

artículo científico publicado en 2011

IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone.

artículo científico publicado en 2003

IgE‐cross‐blocking antibodies to <i>Fagales</i> following sublingual immunotherapy with recombinant Bet v 1

artículo científico publicado en 2021

Interaction of allergens, major histocompatibility complex molecules, and T cell receptors: a 'ménage à trois' that opens new avenues for therapeutic intervention in type I allergy

artículo científico publicado en 2011

Mapping the interactions between a major pollen allergen and human IgE antibodies

artículo científico publicado en 2010

Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules

artículo científico publicado en 2009

Molecular and functional analysis of the antigen receptor of Art v 1-specific helper T lymphocytes.

artículo científico publicado en 2007

NSG mice humanized with allergen-specific T-cell lines as in vivo model of respiratory allergy

scientific article published on 07 March 2020

Natural self-assembly of allergen-S-layer fusion proteins is no prerequisite for reduced allergenicity and T cell stimulatory capacity.

artículo científico publicado en 2009

PD-1 has a unique capacity to inhibit allergen-specific human CD4 T cell responses

artículo científico publicado en 2018

Prevention of allergy by virus-like nanoparticles (VNP) delivering shielded versions of major allergens in a humanized murine allergy model

artículo científico publicado en 2018

Staphylococcus aureus fibronectin-binding protein specifically binds IgE from patients with atopic dermatitis and requires antigen presentation for cellular immune responses.

artículo científico publicado en 2011

Sublingual immunotherapy induces IL-10-producing T regulatory cells, allergen-specific T-cell tolerance, and immune deviation

artículo científico publicado en 2007

Sublingual immunotherapy with recombinant Mal d 1 downregulates the allergen-specific Th2 response

scientific article published on 10 April 2019

Successful sublingual immunotherapy with birch pollen has limited effects on concomitant food allergy to apple and the immune response to the Bet v 1 homolog Mal d 1.

artículo científico publicado en 2007

T Cell Epitope-Containing Domains of Ragweed Amb a 1 and Mugwort Art v 6 Modulate Immunologic Responses in Humans and Mice

artículo científico publicado en 2017

Targeting the cysteine-stabilized fold of Art v 1 for immunotherapy of Artemisia pollen allergy

artículo científico publicado en 2010

The T cell response to Art v 1, the major mugwort pollen allergen, is dominated by one epitope.

artículo científico publicado en 2002

The T-cell response to Amb a 1 is characterized by 3 dominant epitopes and multiple MHC restriction elements

artículo científico publicado en 2010

The alpha and beta subchain of Amb a 1, the major ragweed-pollen allergen show divergent reactivity at the IgE and T-cell level.

artículo científico publicado en 2009

The cytokine environment influence on human skin-derived T cells

The diversity of Bet v 1–specific IgG 4 antibodies remains mostly constant during the course of birch pollen immunotherapy

scientific article published on 02 July 2015

The spectrum of allergens in ragweed and mugwort pollen

artículo científico publicado en 2005

The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus

artículo científico publicado en 2006

Trimolecular complex formation of IgE, Fc epsilon RI, and a recombinant nonanaphylactic single-chain antibody fragment with high affinity for IgE.

artículo científico publicado en 2009