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Lista de obras de Arne Skerra

A Fab fragment directed against the neural cell adhesion molecule L1 enhances functional recovery after injury of the adult mouse spinal cord

artículo científico publicado en 2014

A HLA-Cw6 specific single-chain antibody fragment (scFv) recognizing a natural killer cell receptor epitope.

artículo científico publicado en 2005

A Tetrahedral Boronic Acid Diester Formed by an Unnatural Amino Acid in the Ligand Pocket of an Engineered Lipocalin

scientific article published on 07 November 2019

A Zn(II)-binding site engineered into retinol-binding protein exhibits metal-ion specificity and allows highly efficient affinity purification with a newly designed metal ligand

artículo científico publicado en 1996

A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds

scientific article published on 28 December 2019

A disulfide-free single-domain V(L) intrabody with blocking activity towards huntingtin reveals a novel mode of epitope recognition

artículo científico publicado en 2011

A general vector, pASK84, for cloning, bacterial production, and single-step purification of antibody Fab fragments

artículo científico publicado en 1994

A generic strategy for subcloning antibody variable regions from the scFv phage display vector pCANTAB 5 E into pASK85 permits the economical production of F(ab) fragments and leads to improved recombinant immunoglobulin stability

artículo científico publicado en 2002

A new crystal form of human tear lipocalin reveals high flexibility in the loop region and induced fit in the ligand cavity

artículo científico publicado en 2009

A novel method for the N-terminal modification of native proteins

artículo científico publicado en 2004

A photoswitchable neurotransmitter analogue bound to its receptor

artículo científico publicado en 2013

A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery

artículo científico publicado en 2018

A system for concomitant overexpression of four periplasmic folding catalysts to improve secretory protein production in Escherichia coli

artículo científico publicado en 2006

ANTICALIgN: visualizing, editing and analyzing combined nucleotide and amino acid sequence alignments for combinatorial protein engineering

artículo científico publicado en 2016

Aligning, analyzing, and visualizing sequences for antibody engineering: Automated recognition of immunoglobulin variable region features

artículo científico publicado en 2016

Alternative Protein Scaffolds as Novel Biotherapeutics

article published in 2015

Alternative binding proteins get mature: Rivalling antibodies

article published in 2008

Alternative binding proteins: anticalins - harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding activities

artículo científico publicado en 2008

Alternative non-antibody scaffolds for molecular recognition

artículo científico publicado en 2007

Amination of Ketones by Employing Two New (S)-Selective ω-Transaminases and the His-Tagged ω-TA from Vibrio fluvialis

article

An engineered lipocalin specific for CTLA-4 reveals a combining site with structural and conformational features similar to antibodies.

scholarly article

Anticalins as an alternative to antibody technology

artículo científico publicado en 2005

Anticalins directed against the fibronectin extra domain B as diagnostic tracers for glioblastomas

artículo científico publicado en 2015

Anticalins directed against vascular endothelial growth factor receptor 3 (VEGFR-3) with picomolar affinities show potential for medical therapy and in vivo imaging

artículo científico publicado en 2016

Anticalins in drug development

artículo científico publicado en 2005

Anticalins small engineered binding proteins based on the lipocalin scaffold

artículo científico publicado en 2012

Anticalins: An emerging class of novel biologics to treat cancer and other severe diseases

Anticalins: exploiting a non-Ig scaffold with hypervariable loops for the engineering of binding proteins

artículo científico publicado en 2013

Anticalins: the lipocalin family as a novel protein scaffold for the development of next-generation immunotherapies

artículo científico publicado en 2007

Anticalin® Proteins as Therapeutic Agents in Human Diseases

artículo científico publicado en 2018

Applications of a peptide ligand for streptavidin: the Strep-tag.

artículo científico publicado en 1999

Bacterial expression of immunoglobulin fragments

artículo científico publicado en 1993

Bacterial production and functional characterization of the Fab fragment of the murine IgG1/lambda monoclonal antibody cmHsp70.1, a reagent for tumour diagnostics

artículo científico publicado en 2010

Bifunctional and multimeric complexes of streptavidin fused to single chain antibodies (scFv)

artículo científico publicado en 1995

Binding proteins from alternative scaffolds

artículo científico publicado en 2004

Biochemical analysis of recombinant AlkJ from Pseudomonas putida reveals a membrane-associated, flavin adenine dinucleotide-dependent dehydrogenase suitable for the biosynthetic production of aliphatic aldehydes

artículo científico publicado en 2014

Biochemical characterization of the recombinant human Nogo-A ectodomain

artículo científico publicado en 2007

Biochemie 2009

Biosynthesis of a fluorescent protein with extreme pseudo-Stokes shift by introducing a genetically encoded non-natural amino acid outside the fluorophore.

artículo científico publicado en 2011

Cloning, bacterial synthesis, and characterization of immunoglobulin variable regions of a monoclonal antibody specific for the hepatitis B virus X protein

artículo científico publicado en 1998

Colony assays for antibody fragments expressed in bacteria

artículo científico publicado en 1991

Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin

artículo científico publicado en 2013

Comparative analysis reveals selective recognition of glycans by the dendritic cell receptors DC-SIGN and Langerin

artículo científico publicado en 2011

Comparative ligand-binding analysis of ten human lipocalins

artículo científico publicado en 2006

Comparison of enzymatic properties and small molecule inhibition of γ-glutamyltranspeptidases from pathogenic and commensal bacteria

artículo científico publicado en 2016

Construction of an artificial receptor protein ("anticalin") based on the human apolipoprotein D.

artículo científico publicado en 2004

Coupled Enzymatic Alcohol-to-Amine Conversion of Isosorbide using Engineered Transaminases and Dehydrogenases

Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel

artículo científico publicado en 2010

Crystal structure of the human odorant binding protein, OBPIIa

artículo científico publicado en 2015

Crystal structure of the sensory domain ofEscherichia coliCadC, a member of the ToxR-like protein family

artículo científico publicado en 2011

Crystal structure of the ω-aminotransferase from Paracoccus denitrificans and its phylogenetic relationship with other class III aminotransferases that have biotechnological potential

artículo científico publicado en 2013

Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. alcohol dehydrogenase toward NADH cosubstrate specificity

artículo científico publicado en 2013

Crystallographic analysis of an "anticalin" with tailored specificity for fluorescein reveals high structural plasticity of the lipocalin loop region

artículo científico publicado en 2003

Current Strategies for Pharmacokinetic Optimization

DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis

artículo científico publicado en 2008

Deactivation of the E. coli pH stress sensor CadC by cadaverine

artículo científico publicado en 2012

Derivatization of antibody Fab fragments: a designer enzyme for native protein modification

artículo científico publicado en 2014

Design and characterization of a modular membrane protein anchor to functionalize the moss Physcomitrella patens with extracellular catalytic and/or binding activities

artículo científico publicado en 2014

Design of a surrogate Anticalin® protein directed against CD98hc for preclinical studies in mice

artículo científico publicado en 2020

Detection of irradiation-induced, membrane heat shock protein 70 (Hsp70) in mouse tumors using Hsp70 Fab fragment

artículo científico publicado en 2011

Dkk-1 inhibits intestinal epithelial cell migration by attenuating directional polarization of leading edge cells

artículo científico publicado en 2009

Duocalins: Engineered Ligand-Binding Proteins with Dual Specificity Derived from the Lipocalin Fold ⬇️

artículo científico publicado el 1 de septiembre de 2001

Endoplasmic Reticulum Stress Response Promotes Cytotoxic Phenotype of CD8 + Intraepithelial Lymphocytes in a Mouse Model for Crohn's Disease-like Ileitis

article

Enge molekulare Erkennung von Benzo[a ]pyren durch einen hochaffinen Antikörper

Engineered Fv fragments as a tool for the one-step purification of integral multisubunit membrane protein complexes

artículo científico publicado en 1995

Engineered protein scaffolds as next-generation antibody therapeutics.

artículo científico publicado en 2009

Engineering of alanine dehydrogenase from Bacillus subtilis for novel cofactor specificity

artículo científico publicado en 2015

Engineering of an orthogonal aminoacyl-tRNA synthetase for efficient incorporation of the non-natural amino acid O-methyl-L-tyrosine using fluorescence-based bacterial cell sorting

artículo científico publicado en 2010

Enhanced in vivo efficacy of a type I interferon superagonist with extended plasma half-life in a mouse model of multiple sclerosis

artículo científico publicado en 2014

Epitope mapping of the neuronal growth inhibitor Nogo-A for the Nogo receptor and the cognate monoclonal antibody IN-1 by means of the SPOT technique

artículo científico publicado en 2007

Expression and Purification of EPHA2 Tyrosine Kinase Domain for Crystallographic and NMR Studies

artículo científico publicado en 2016

Extra-domain B in Oncofetal Fibronectin Structurally Promotes Fibrillar Head-to-tail Dimerization of Extracellular Matrix Protein

artículo científico publicado en 2012

Fermenter production of an artificial fab fragment, rationally designed for the antigen cystatin, and its optimized crystallization through constant domain shuffling

artículo científico publicado en 1995

Filter screening of antibody Fab fragments secreted from individual bacterial colonies: Specific detection of antigen binding with a two-membrane system

article

First In-Human Medical Imaging with a PASylated 89Zr-Labeled Anti-HER2 Fab-Fragment in a Patient with Metastatic Breast Cancer

scientific article published on 20 April 2020

Fixation of gaseous CO2 by reversing a decarboxylase for the biocatalytic synthesis of the essential amino acid l-methionine

Functional characterization of a VEGF-A-targeting Anticalin, prototype of a novel therapeutic human protein class

artículo científico publicado en 2015

Functional humanization of an anti-CD16 Fab fragment: obstacles of switching from murine {lambda} to human {lambda} or {kappa} light chains

artículo científico publicado en 2008

Functional humanization of an anti-CD30 Fab fragment for the immunotherapy of Hodgkin's lymphoma using an in vitro evolution approach.

artículo científico publicado en 2004

Fusion of a recombinant antibody fragment with a homo-amino-acid polymer: effects on biophysical properties and prolonged plasma half-life

artículo científico publicado en 2007

Generation of anticalins with specificity for a nonsymmetric phthalic acid ester

artículo científico publicado en 2002

Half-Life Extension of Therapeutic Proteins via Genetic Fusion to Recombinant PEG Mimetics

Half-life extension and non-human primate pharmacokinetic safety studies of i-body AD-114 targeting human CXCR4

scientific article published on 23 August 2019

High contrast tumor imaging with radio-labeled antibody Fab fragments tailored for optimized pharmacokinetics via PASylation

artículo científico publicado en 2015

High molecular mass radioimmunoconjugates are promising for intraperitoneal α-emitter immunotherapy due to prolonged retention in the peritoneum

artículo científico publicado en 2012

High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer β-amyloid peptide

artículo científico publicado en 2016

High-affinity recognition of lanthanide(III) chelate complexes by a reprogrammed human lipocalin 2

artículo científico publicado en 2009

High-throughput sorting of an Anticalin library via EspP-mediated functional display on the Escherichia coli cell surface

artículo científico publicado en 2010

Identification of potential substrate proteins for the periplasmic Escherichia coli chaperone Skp.

artículo científico publicado en 2008

Imitating the humoral immune response

artículo científico publicado en 2003

Immobilization of histidine-tagged proteins on gold surfaces using chelator thioalkanes

artículo científico publicado en 1999

Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site

artículo científico publicado en 2002

Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation

artículo científico publicado en 2016

Innenrücktitelbild: Neuprogrammierung von humanem Siderocalin zur Neutralisierung von Petrobactin, dem essenziellen Eisenfänger des Milzbrand-Bazillus (Angew. Chem. 44/2018)

Inside Back Cover: Reprogramming Human Siderocalin To Neutralize Petrobactin, the Essential Iron Scavenger of Anthrax Bacillus (Angew. Chem. Int. Ed. 44/2018)

scholarly article by Martin Dauner et al published 17 October 2018 in Angewandte Chemie International Edition

Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways

artículo científico publicado en 2010

Intracellular expression of a cloned antibody fragment interferes with hepatitis B virus surface antigen secretion

artículo científico publicado en 1999

Intravenous application of an anticalin dramatically lowers plasma digoxin levels and reduces its toxic effects in rats

article

Lipocalins as a scaffold

artículo científico publicado en 2000

Lipocalins in drug discovery: from natural ligand-binding proteins to "anticalins".

artículo científico publicado en 2005

Long-Acting PASylated Leptin Ameliorates Obesity by Promoting Satiety and Preventing Hypometabolism in Leptin-Deficient Lep(ob/ob) Mice

artículo científico

Molecular Design of <sup>68</sup>Ga- and <sup>89</sup>Zr-Labeled Anticalin Radioligands for PET-Imaging of PSMA-Positive Tumors

Molecular interaction between the Strep-tag affinity peptide and its cognate target, streptavidin

artículo científico publicado en 1996

Moos ganz groß — der PhyscoFilter

NMR Structure and Dynamics of the Engineered Fluorescein-Binding Lipocalin FluA Reveal Rigidification of β-Barrel and Variable Loops upon Enthalpy-Driven Ligand Binding

artículo científico publicado en 2009

NMR structure of lipoprotein YxeF from Bacillus subtilis reveals a calycin fold and distant homology with the lipocalin Blc from Escherichia coli

artículo científico publicado en 2012

Neuartige biopharmazeutische Wirkstoffe auf der Grundlage von Lipocalinen

Neuprogrammierung von humanem Siderocalin zur Neutralisierung von Petrobactin, dem essenziellen Eisenfänger des Milzbrand-Bazillus

Neutrophil gelatinase-associated lipocalin expresses antimicrobial activity by interfering with L-norepinephrine-mediated bacterial iron acquisition

artículo científico publicado en 2010

New insights into the signaling mechanism of the pH-responsive, membrane-integrated transcriptional activator CadC of Escherichia coli

artículo científico publicado en 2011

Non-Antibody Scaffolds

Non-Antibody Scaffolds as Alternative Therapeutic Agents

Novel Monoclonal Antibodies Recognizing Human Prostate-Specific Membrane Antigen (PSMA) as Research and Theranostic Tools.

artículo científico publicado en 2017

Novel serial positive enrichment technology enables clinical multiparameter cell sorting

artículo científico publicado en 2012

One-step affinity purification of bacterially produced proteins by means of the "Strep tag" and immobilized recombinant core streptavidin

artículo científico publicado en 1994

Optimisation of a system for the co-translational incorporation of a keto amino acid and its application to a tumour-specific Anticalin

artículo científico publicado en 2015

PAS-cal: A repetitive peptide sequence calibration standard for MALDI mass spectrometry

artículo científico publicado en 2014

PAS-cal: a generic recombinant peptide calibration standard for mass spectrometry

artículo científico publicado en 2014

PASylated Coversin, a C5-Specific Complement Inhibitor with Extended Pharmacokinetics, Shows Enhanced Anti-Hemolytic Activity in Vitro

artículo científico publicado en 2016

PASylated Thymosin α1: A Long-Acting Immunostimulatory Peptide for Applications in Oncology and Virology

artículo científico publicado en 2020

PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis

scientific article published on 09 December 2019

PASylation of Murine Leptin Leads to Extended Plasma Half-Life and Enhanced in Vivo Efficacy

PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins

artículo científico publicado en 2013

Periplasmic chaperones used to enhance functional secretion of proteins in E. coli

artículo científico publicado en 2011

Phosphorothioate primers improve the amplification of DNA sequences by DNA polymerases with proofreading activity

artículo científico publicado en 1992

Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization

artículo científico publicado en 2020

ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

article

Rapid expression cloning of human immunoglobulin Fab fragments for the analysis of antigen specificity of B cell lymphomas and anti-idiotype lymphoma vaccination

article

Rational Design of an Anticalin-Type Sugar-Binding Protein Using a Genetically Encoded Boronate Side Chain.

artículo científico publicado en 2017

Rational engineering of a fluorescein-binding anticalin for improved ligand affinity

artículo científico publicado en 2005

Regeneration of auditory nerve following complete sectioning and intrathecal application of the IN-1 antibody

artículo científico publicado en 2002

Reprogramming Human Siderocalin To Neutralize Petrobactin, the Essential Iron Scavenger of Anthrax Bacillus

scholarly article by Martin Dauner et al published 2 October 2018 in Angewandte Chemie

Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity

artículo científico publicado en 2016

Resonance assignments for the 21 kDa engineered fluorescein-binding lipocalin FluA.

artículo científico publicado en 2003

Scavenging Bacterial Siderophores with Engineered Lipocalin Proteins as an Alternative Antimicrobial Strategy

scientific article published on 13 December 2019

Secretion and in vivo folding of the Fab fragment of the antibody McPC603 in Escherichia coli: influence of disulphides and cis-prolines ⬇️

artículo científico publicado el 1 de diciembre de 1991

Selection and characterization of Anticalins targeting human prostate-specific membrane antigen (PSMA).

artículo científico publicado en 2016

Sequence analysis and bacterial production of the anti-c-myc antibody 9E10: the V(H) domain has an extended CDR-H3 and exhibits unusual solubility

artículo científico publicado en 1997

Single-step purification of a bacterially expressed antibody Fv fragment by immobilized metal affinity chromatography in the presence of betaine

artículo científico publicado en 1993

Small antibody-like proteins with prescribed ligand specificities derived from the lipocalin fold.

artículo científico publicado en 1999

Solubility engineering and crystallization of human apolipoprotein D.

artículo científico publicado en 2005

Sortase-catalyzed in vitro functionalization of a HER2-specific recombinant Fab for tumor targeting of the plant cytotoxin gelonin

artículo científico publicado en 2013

Stability engineering of the Geobacillus stearothermophilus alcohol dehydrogenase and application for the synthesis of a polyamide 12 precursor

artículo científico publicado en 2015

Structural Basis for the Enzymatic Formation of the Key Strawberry Flavor Compound 4-Hydroxy-2,5-dimethyl-3(2H)-furanone

artículo científico publicado en 2013

Structural Basis for the Interconversion of Maltodextrins by MalQ, the Amylomaltase of Escherichia coli.

artículo científico publicado en 2015

Structural Basis for the Specific Cotranslational Incorporation of p-Boronophenylalanine into Biosynthetic Proteins.

artículo científico publicado en 2018

Structural analysis of the L-alanoyl-D-glutamate endopeptidase domain of Listeria bacteriophage endolysin Ply500 reveals a new member of the LAS peptidase family

artículo científico publicado en 2008

Structural and biochemical analyses reveal a monomeric state of the bacterial lipocalin Blc

artículo científico publicado en 2010

Structural basis for cellulose binding by the type A carbohydrate-binding module 64 of Spirochaeta thermophila

artículo científico publicado en 2016

Structural differences between the ectodomains of murine and human CD98hc

scientific article published on 23 April 2019

Structural features of the McPC603 Fab fragment not defined in the X-ray structure

artículo científico publicado en 1990

Structural insight into the dual ligand specificity and mode of high density lipoprotein association of apolipoprotein D

artículo científico publicado en 2007

Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein

artículo científico publicado en 2003

Structural mechanism of specific ligand recognition by a lipocalin tailored for the complexation of digoxigenin

artículo científico publicado en 2003

Structure of lumazine protein, an optical transponder of luminescent bacteria

artículo científico publicado en 2008

Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism

artículo científico publicado en 2010

Structure of the periplasmic chaperone Skp suggests functional similarity with cytosolic chaperones despite differing architecture

artículo científico publicado en 2004

Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy

artículo científico publicado en 2014

Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody

artículo científico publicado en 2010

Temperature and pressure dependence of protein stability: the engineered fluorescein-binding lipocalin FluA shows an elliptic phase diagram

artículo científico publicado en 2008

The 1.8-A crystal structure of alpha1-acid glycoprotein (Orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin

artículo científico publicado en 2008

The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands

scientific journal article

The Escherichia coli-derived Fab fragment of the IgM/kappa antibody IN-1 recognizes and neutralizes myelin-associated inhibitors of neurite growth

artículo científico publicado en 1996

The Strep-tag system for one-step affinity purification of proteins from mammalian cell culture

artículo científico publicado en 2015

The Strep-tag system for one-step purification and high-affinity detection or capturing of proteins

artículo científico publicado en 2007

The bilin-binding protein of Pieris brassicae. cDNA sequence and regulation of expression reveal distinct features of this insect pigment protein

artículo científico publicado en 1994

The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site

artículo científico publicado en 2008

The crystal structure of human α(1)-microglobulin reveals a potential haem-binding site

artículo científico publicado en 2012

The crystal structure of the bacteriophage PSA endolysin reveals a unique fold responsible for specific recognition of Listeria cell walls

artículo científico publicado en 2006

The crystal structure of the human (S100A8/S100A9)2 heterotetramer, calprotectin, illustrates how conformational changes of interacting alpha-helices can determine specific association of two EF-hand proteins

artículo científico publicado en 2007

The dimeric crystal structure of the human fertility lipocalin glycodelin reveals a protein scaffold for the presentation of complex glycans

artículo científico publicado en 2015

The functional expression of antibody Fv fragments in Escherichia coli: improved vectors and a generally applicable purification technique

artículo científico publicado en 1991

The menagerie of human lipocalins: a natural protein scaffold for molecular recognition of physiological compounds

artículo científico publicado en 2015

The periplasmic E. coli chaperone Skp is a trimer in solution: biophysical and preliminary crystallographic characterization

artículo científico publicado en 2004

The polypeptide biophysics of proline/alanine-rich sequences (PAS): Recombinant biopolymers with PEG-like properties

artículo científico publicado en 2017

The random peptide library-assisted engineering of a C-terminal affinity peptide, useful for the detection and purification of a functional Ig Fv fragment.

artículo científico publicado en 1993

The rational construction of an antibody against cystatin: lessons from the crystal structure of an artificial Fab fragment

artículo científico publicado en 1997

The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops

artículo científico publicado en 2008

Tight Molecular Recognition of Benzo[a]pyrene by a High-Affinity Antibody

artículo científico publicado en 2017

Translating the Concept of Bispecific Antibodies to Engineering Heterodimeric Phosphotriesterases with Broad Organophosphate Substrate Recognition

artículo científico publicado en 2020

Treatment of diet-induced lipodystrophic C57BL/6J mice with long-acting PASylated leptin normalises insulin sensitivity and hepatic steatosis by promoting lipid utilisation

artículo científico publicado en 2016

Tumor Uptake of Anti-CD20 Fabs Depends on Tumor Perfusion

artículo científico publicado en 2016

Tuning ligand affinity, specificity, and folding stability of an engineered lipocalin variant -- a so-called 'anticalin' -- using a molecular random approach

artículo científico publicado en 2002

Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replication

artículo científico publicado en 2018

Ultrafast electron transfer in the complex between fluorescein and a cognate engineered lipocalin protein, a so-called anticalin

artículo científico publicado en 2002

Use of Thiophilic Adsorption Chromatography for the One-Step Purification of a Bacterially Produced Antibody Fab Fragment without the Need for an Affinity Tag

article by Markus Fiedler & Arne Skerra published December 1999 in Protein Expression and Purification

Use of an albumin-binding domain for the selective immobilisation of recombinant capture antibody fragments on ELISA plates

artículo científico publicado en 1998

Use of the tetracycline promoter for the tightly regulated production of a murine antibody fragment in Escherichia coli

article

[34] Expression of functional antibody Fv and Fab fragments in Escherichia coli

artículo científico publicado en 1989

proBA complementation of an auxotrophic E. coli strain improves plasmid stability and expression yield during fermenter production of a recombinant antibody fragment

artículo científico publicado en 2001

β-Barrel scaffolds for the grafting of extracellular loops from G-protein-coupled receptors

artículo científico publicado en 2012

⁸⁹Zr-Labeled Versus ¹²⁴I-Labeled αHER2 Fab with Optimized Plasma Half-Life for High-Contrast Tumor Imaging In Vivo

artículo científico publicado en 2015

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