Lista de obras -

A double hit implicates DIAPH3 as an autism risk gene.

artículo científico publicado en 2010

A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy

scientific article published on 24 June 2020

ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization

scientific article published on 19 May 2020

An Image-Based miRNA screen identifies miRNA-135s as regulators of CNS axon growth and regeneration by targeting Krüppel-like factor 4.

artículo científico publicado en 2017

Anatomical distribution of the chemorepellent semaphorin III/collapsin-1 in the adult rat and human brain: Predominant expression in structures of the olfactory-hippocampal pathway and the motor system ⬇️

artículo científico publicado el 1 de abril de 1998

Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis

artículo científico

Antagonizing Increased miR-135a Levels at the Chronic Stage of Experimental TLE Reduces Spontaneous Recurrent Seizures

artículo científico publicado en 2019

Axon guidance in the dopamine system.

scientific article published on January 2009

Axon guidance proteins in neurological disorders.

artículo científico

C9orf72 ablation in mice does not cause motor neuron degeneration or motor deficits

artículo científico publicado en 2015

C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis

artículo científico publicado en 2014

CFEOM1-associated kinesin KIF21A is a cortical microtubule growth inhibitor.

artículo científico publicado en 2013

Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment

artículo científico publicado en 2017

Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

artículo científico

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

artículo científico

DeActs: genetically encoded tools for perturbing the actin cytoskeleton in single cells.

artículo científico publicado en 2017

Detailed analysis of the genetic and epigenetic signatures of iPSC-derived mesodiencephalic dopaminergic neurons.

artículo científico publicado en 2014

Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures

artículo científico publicado en 2013

Differential expression of estrogen receptor mRNA and protein in the female rat preoptic area ⬇️

artículo científico publicado el 19 de diciembre de 1997

Disrupted neuronal trafficking in amyotrophic lateral sclerosis

scientific article published on 05 February 2019

Dysregulation of Semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility

artículo científico publicado en 2011

Emerging roles for semaphorins in neural regeneration

artículo científico publicado en 2001

Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats.

artículo científico publicado en 2012

Exposure to the Amino Acids Histidine, Lysine, and Threonine Reduces mTOR Activity and Affects Neurodevelopment in a Human Cerebral Organoid Model

artículo científico publicado en 2022

FUS mutations in familial amyotrophic lateral sclerosis in the Netherlands.

artículo científico publicado en 2010

Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development.

artículo científico publicado en 2015

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

artículo científico publicado en 2016

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis

artículo científico publicado en 2009

Genome-wide microRNA profiling of human temporal lobe epilepsy identifies modulators of the immune response

artículo científico publicado en 2012

Getting connected in the dopamine system.

artículo científico publicado en 2008

Getting neural circuits into shape with semaphorins ⬇️

artículo científico publicado el 16 de agosto de 2012

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.

artículo científico publicado en 2018

High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling molecule

artículo científico publicado en 2005

Kinetic and spectroscopic characterization of the putative monooxygenase domain of human MICAL-1

artículo científico publicado en 2011

Long non-coding RNAs in motor neuron development and disease

scientific article published on 24 September 2020

MICAL flavoprotein monooxygenases: expression during neural development and following spinal cord injuries in the rat.

artículo científico publicado en 2005

MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis

artículo científico publicado en 2011

MICALs in control of the cytoskeleton, exocytosis, and cell death ⬇️

artículo científico publicado el 6 de agosto de 2011

MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion

artículo científico publicado en 2002

MeCP2 deficiency disrupts axonal guidance, fasciculation, and targeting by altering Semaphorin 3F function.

artículo científico publicado en 2009

Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development

artículo científico publicado en 2014

NIPA1 polyalanine repeat expansions are associated with amyotrophic lateral sclerosis

artículo científico publicado en 2012

Neuromuscular Junction-on-a-Chip: ALS disease modeling and read-out development in microfluidic devices

scientific article published on 31 December 2020

Neuropeptide delivery to the brain: a von Willebrand factor signal peptide to direct neuropeptide secretion.

artículo científico publicado en 2010

Nolz1 expression is required in dopaminergic axon guidance and striatal innervation

scientific article published on 19 June 2020

Peripheral nerve injury fails to induce growth of lesioned ascending dorsal column axons into spinal cord scar tissue expressing the axon repellent Semaphorin3A.

artículo científico publicado en 2001

Protein aggregation in amyotrophic lateral sclerosis.

artículo científico

R-Ras fills another GAP in semaphorin signalling

artículo científico publicado en 2005

Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers

artículo científico publicado en 2011

Regulation of semaphorin III/collapsin-1 gene expression during peripheral nerve regeneration.

artículo científico publicado en 1998

Repulsive guidance molecule a (RGMa) induces neuropathological and behavioral changes that closely resemble Parkinson's disease.

artículo científico

S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration.

artículo científico publicado en 2013

Semaphorin 7A Promotes Chemokine-Driven Dendritic Cell Migration

artículo científico publicado en 2015

Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin

scientific journal article

Semaphorin function in neural plasticity and disease.

artículo científico publicado en 2009

Semaphorin junction: making tracks toward neural connectivity

scientific journal article

Semaphorin signaling: progress made and promises ahead.

scientific article published on April 2008

Semaphorin signalling during development

artículo científico publicado en 2014

Semaphorin7A and its receptors: Pleiotropic regulators of immune cell function, bone homeostasis, and neural development ⬇️

artículo científico publicado el 16 de enero de 2013

Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence

artículo científico publicado en 2015

Sensory Axon Growth Requires Spatiotemporal Integration of CaSR and TrkB Signaling

scientific article published on 23 May 2019

Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors

artículo científico publicado en 2022

SnapShot: Axon Guidance ⬇️

artículo científico publicado el 11 de abril de 2013

SnapShot: Axon Guidance II ⬇️

artículo científico publicado el 25 de abril de 2013

Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively

artículo científico publicado en 2005

Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain.

artículo científico publicado en 2013

Structural basis of semaphorin-plexin cis interaction

artículo científico publicado en 2020

Structure of the Repulsive Guidance Molecule (RGM)-Neogenin Signaling Hub

artículo científico publicado en 2013

Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula

artículo científico publicado en 2014

TRPC3 is a major contributor to functional heterogeneity of cerebellar Purkinje cells

artículo científico publicado en 2019

Taking a risk: a therapeutic focus on ataxin-2 in amyotrophic lateral sclerosis?

artículo científico

The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections

scientific journal article

Transcriptional repression of Plxnc1 by Lmx1a and Lmx1b directs topographic dopaminergic circuit formation.

artículo científico publicado en 2017

UNC13A is a modifier of survival in amyotrophic lateral sclerosis

artículo científico publicado en 2011

VCP mutations in familial and sporadic amyotrophic lateral sclerosis

scientific article published on 10 November 2011

Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem

scientific journal article

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.

artículo científico publicado en 2013

shRNA-induced saturation of the microRNA pathway in the rat brain.

artículo científico publicado en 2014

unc5c haploinsufficient phenotype: striking similarities with the dcc haploinsufficiency model.

artículo científico publicado en 2013

Lista de obras de

A double hit implicates DIAPH3 as an autism risk gene.

A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy

ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization

An Image-Based miRNA screen identifies miRNA-135s as regulators of CNS axon growth and regeneration by targeting Krüppel-like factor 4.

Anatomical distribution of the chemorepellent semaphorin III/collapsin-1 in the adult rat and human brain: Predominant expression in structures of the olfactory-hippocampal pathway and the motor system ⬇️

Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis

Antagonizing Increased miR-135a Levels at the Chronic Stage of Experimental TLE Reduces Spontaneous Recurrent Seizures

Axon guidance in the dopamine system.

Axon guidance proteins in neurological disorders.

C9orf72 ablation in mice does not cause motor neuron degeneration or motor deficits

C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis

CFEOM1-associated kinesin KIF21A is a cortical microtubule growth inhibitor.

Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment

Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

DeActs: genetically encoded tools for perturbing the actin cytoskeleton in single cells.

Detailed analysis of the genetic and epigenetic signatures of iPSC-derived mesodiencephalic dopaminergic neurons.

Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures

Differential expression of estrogen receptor mRNA and protein in the female rat preoptic area ⬇️

Disrupted neuronal trafficking in amyotrophic lateral sclerosis

Dysregulation of Semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility

Emerging roles for semaphorins in neural regeneration

Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats.

Exposure to the Amino Acids Histidine, Lysine, and Threonine Reduces mTOR Activity and Affects Neurodevelopment in a Human Cerebral Organoid Model

FUS mutations in familial amyotrophic lateral sclerosis in the Netherlands.

Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development.

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis

Genome-wide microRNA profiling of human temporal lobe epilepsy identifies modulators of the immune response

Getting connected in the dopamine system.

Getting neural circuits into shape with semaphorins ⬇️

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.

High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling molecule

Kinetic and spectroscopic characterization of the putative monooxygenase domain of human MICAL-1

Long non-coding RNAs in motor neuron development and disease

MICAL flavoprotein monooxygenases: expression during neural development and following spinal cord injuries in the rat.

MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis

MICALs in control of the cytoskeleton, exocytosis, and cell death ⬇️

MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion

MeCP2 deficiency disrupts axonal guidance, fasciculation, and targeting by altering Semaphorin 3F function.

Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development

NIPA1 polyalanine repeat expansions are associated with amyotrophic lateral sclerosis

Neuromuscular Junction-on-a-Chip: ALS disease modeling and read-out development in microfluidic devices

Neuropeptide delivery to the brain: a von Willebrand factor signal peptide to direct neuropeptide secretion.

Nolz1 expression is required in dopaminergic axon guidance and striatal innervation

Peripheral nerve injury fails to induce growth of lesioned ascending dorsal column axons into spinal cord scar tissue expressing the axon repellent Semaphorin3A.

Protein aggregation in amyotrophic lateral sclerosis.

R-Ras fills another GAP in semaphorin signalling

Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers

Regulation of semaphorin III/collapsin-1 gene expression during peripheral nerve regeneration.

Repulsive guidance molecule a (RGMa) induces neuropathological and behavioral changes that closely resemble Parkinson's disease.

S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration.

Semaphorin 7A Promotes Chemokine-Driven Dendritic Cell Migration

Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin

Semaphorin function in neural plasticity and disease.

Semaphorin junction: making tracks toward neural connectivity

Semaphorin signaling: progress made and promises ahead.

Semaphorin signalling during development

Semaphorin7A and its receptors: Pleiotropic regulators of immune cell function, bone homeostasis, and neural development ⬇️

Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence

Sensory Axon Growth Requires Spatiotemporal Integration of CaSR and TrkB Signaling

Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors

SnapShot: Axon Guidance ⬇️

SnapShot: Axon Guidance II ⬇️

Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively

Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain.

Structural basis of semaphorin-plexin cis interaction

Structure of the Repulsive Guidance Molecule (RGM)-Neogenin Signaling Hub

Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula

TRPC3 is a major contributor to functional heterogeneity of cerebellar Purkinje cells

Taking a risk: a therapeutic focus on ataxin-2 in amyotrophic lateral sclerosis?

The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections

Transcriptional repression of Plxnc1 by Lmx1a and Lmx1b directs topographic dopaminergic circuit formation.

UNC13A is a modifier of survival in amyotrophic lateral sclerosis

VCP mutations in familial and sporadic amyotrophic lateral sclerosis

Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.

shRNA-induced saturation of the microRNA pathway in the rat brain.

unc5c haploinsufficient phenotype: striking similarities with the dcc haploinsufficiency model.