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Lista de obras de Christopher J.H. Porter

'Stealth' lipid-based formulations: poly(ethylene glycol)-mediated digestion inhibition improves oral bioavailability of a model poorly water soluble drug

artículo científico publicado en 2014

50years of oral lipid-based formulations: Provenance, progress and future perspectives

artículo científico publicado en 2016

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

artículo científico publicado en 2019

A Comparison of the Pharmacokinetics and Pulmonary Lymphatic Exposure of a Generation 4 PEGylated Dendrimer Following Intravenous and Aerosol Administration to Rats and Sheep

artículo científico publicado en 2015

A Nonionic Polyethylene Oxide (PEO) Surfactant Model: Experimental and Molecular Dynamics Studies of Kolliphor EL

artículo científico publicado en 2018

A comparison of changes to doxorubicin pharmacokinetics, antitumor activity, and toxicity mediated by PEGylated dendrimer and PEGylated liposome drug delivery systems.

artículo científico publicado en 2011

A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists

scientific article published on 31 December 2018

A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes

artículo científico publicado en 2021

A lipid-based liquid crystalline matrix that provides sustained release and enhanced oral bioavailability for a model poorly water soluble drug in rats

artículo científico publicado en 2007

A mouse model to evaluate the impact of species, sex, and lipid load on lymphatic drug transport

artículo científico publicado en 2013

A new in vitro lipid digestion - in vivo absorption model to evaluate the mechanisms of drug absorption from lipid-based formulations

artículo científico publicado en 2015

A novel cubic phase of medium chain lipid origin for the delivery of poorly water soluble drugs.

artículo científico publicado en 2004

A physicochemical basis for the extensive intestinal lymphatic transport of a poorly lipid soluble antimalarial, halofantrine hydrochloride, after postprandial administration to dogs.

artículo científico publicado en 2002

A simple quantitative approach for the determination of long and medium chain lipids in bio-relevant matrices by high performance liquid chromatography with refractive index detection.

artículo científico publicado en 2013

An Acute and Coincident Increase in FABP Expression and Lymphatic Lipid and Drug Transport Occurs During Intestinal Infusion of Lipid-Based Drug Formulations to Rats

scientific article published on 01 August 2006

An Evaluation of Optimal PEGylation Strategies for Maximizing the Lymphatic Exposure and Antiviral Activity of Interferon after Subcutaneous Administration.

artículo científico publicado en 2017

An examination of the interplay between enterocyte-based metabolism and lymphatic drug transport in the rat.

artículo científico publicado en 2006

An in vitro digestion test that reflects rat intestinal conditions to probe the importance of formulation digestion vs first pass metabolism in Danazol bioavailability from lipid based formulations

artículo científico publicado en 2014

Association of chemotherapeutic drugs with dendrimer nanocarriers: an assessment of the merits of covalent conjugation compared to noncovalent encapsulation.

artículo científico publicado en 2012

Capping Methotrexate α-Carboxyl Groups Enhances Systemic Exposure and Retains the Cytotoxicity of Drug Conjugated PEGylated Polylysine Dendrimers

artículo científico publicado en 2011

Characterisation and tumour targeting of PEGylated polylysine dendrimers bearing doxorubicin via a pH labile linker.

artículo científico publicado en 2011

Characterization of the drug binding specificity of rat liver fatty acid binding protein.

artículo científico publicado en 2008

Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein

artículo científico publicado en 2014

Choice of nonionic surfactant used to formulate type IIIA self-emulsifying drug delivery systems and the physicochemical properties of the drug have a pronounced influence on the degree of drug supersaturation that develops during in vitro digestion

artículo científico publicado en 2014

Computational Models of the Gastrointestinal Environment. 1. The Effect of Digestion on the Phase Behavior of Intestinal Fluids.

artículo científico publicado en 2017

Computational Models of the Gastrointestinal Environment. 2. Phase Behavior and Drug Solubilization Capacity of a Type I Lipid-Based Drug Formulation after Digestion.

artículo científico publicado en 2016

Computational Models of the Intestinal Environment. 3. The Impact of Cholesterol Content and pH on Mixed Micelle Colloids.

artículo científico publicado en 2017

Computational prediction of drug solubility in lipid based formulation excipients.

artículo científico publicado en 2013

Computational prediction of formulation strategies for beyond-rule-of-5 compounds

artículo científico publicado en 2016

Conjugation of 10 kDa Linear PEG onto Trastuzumab Fab' Is Sufficient to Significantly Enhance Lymphatic Exposure while Preserving in Vitro Biological Activity

artículo científico publicado en 2016

Constitutive Triglyceride Turnover into the Mesenteric Lymph Is Unable to Support Efficient Lymphatic Transport of a Biomimetic Triglyceride Prodrug

artículo científico publicado en 2016

Contribution of lymphatically transported testosterone undecanoate to the systemic exposure of testosterone after oral administration of two andriol formulations in conscious lymph duct-cannulated dogs.

artículo científico publicado en 2003

Correction to "targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?"

scientific article published on 13 October 2011

Correlating in Vitro Solubilization and Supersaturation Profiles with in Vivo Exposure for Lipid Based Formulations of the CETP Inhibitor CP-532,623.

artículo científico publicado en 2017

Cyclic peptide-poly(HPMA) nanotubes as drug delivery vectors: In vitro assessment, pharmacokinetics and biodistribution

scientific article published on 29 March 2018

Dendrimer pharmacokinetics: the effect of size, structure and surface characteristics on ADME properties.

artículo científico

Dietary Docosahexaenoic Acid Supplementation Enhances Expression of Fatty Acid-Binding Protein 5 at the Blood-Brain Barrier and Brain Docosahexaenoic Acid Levels.

artículo científico publicado en 2018

Differences in colloidal structure of PEGylated nanomaterials dictate the likelihood of accelerated blood clearance

artículo científico publicado en 2011

Differences in pre- and post-prandial plasma lipid profiles affect the extraction efficiency of a model highly lipophilic drug from beagle dog plasma

artículo científico publicado el 1 de septiembre de 1997

Digestion of Lipid-Based Formulations Not Only Mediates Changes to Absorption of Poorly Soluble Drugs Due to Differences in Solubilization But Also Reflects Changes to Thermodynamic Activity and Permeability

artículo científico publicado en 2021

Digestion of phospholipids after secretion of bile into the duodenum changes the phase behavior of bile components.

artículo científico publicado en 2014

Does stereoselective lymphatic absorption contribute to the enantioselective pharmacokinetics of halofantrine In Vivo?

artículo científico publicado en 2003

Doxorubicin Conjugation and Drug Linker Chemistry Alter the Intravenous and Pulmonary Pharmacokinetics of a PEGylated Generation 4 Polylysine Dendrimer in Rats

scientific article published on 29 May 2018

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy.

artículo científico publicado en 2017

Engineering Biocoatings To Prolong Drug Release from Supraparticles

scientific article published on 14 August 2019

Enhancing intestinal drug solubilisation using lipid-based delivery systems.

artículo científico publicado en 2007

Enhancing the Oral Absorption of Kinase Inhibitors Using Lipophilic Salts and Lipid Based Formulations

scientific article published on 13 November 2018

Evaluation of the impact of surfactant digestion on the bioavailability of danazol after oral administration of lipidic self-emulsifying formulations to dogs.

artículo científico publicado en 2008

Evaluation of the structural determinants of polymeric precipitation inhibitors using solvent shift methods and principle component analysis.

artículo científico publicado en 2013

Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides.

artículo científico publicado en 2003

Examination of the impact of a range of Pluronic surfactants on the in-vitro solubilisation behaviour and oral bioavailability of lipidic formulations of atovaquone

artículo científico publicado en 2006

Examination of the role of intestinal fatty acid-binding protein in drug absorption using a parallel artificial membrane permeability assay.

artículo científico publicado en 2007

Fatty Acid Binding Proteins Expressed at the Human Blood-Brain Barrier Bind Drugs in an Isoform-Specific Manner

artículo científico publicado en 2015

Fatty Acid Binding Proteins: Potential Chaperones of Cytosolic Drug Transport in the Enterocyte?

artículo científico publicado en 2011

Fatty Acid-Binding Protein 5 Facilitates the Blood-Brain Barrier Transport of Docosahexaenoic Acid.

artículo científico publicado en 2015

Fatty Acid-Binding Protein 5 at the Blood-Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function.

artículo científico publicado en 2016

Fatty Acid-binding Proteins 1 and 2 Differentially Modulate the Activation of Peroxisome Proliferator-activated Receptor α in a Ligand-selective Manner

artículo científico publicado en 2015

Fatty acid binding protein 5 mediates the uptake of fatty acids, but not drugs, into human brain endothelial cells

artículo científico publicado en 2017

Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies.

artículo científico publicado en 2007

From sewer to saviour - targeting the lymphatic system to promote drug exposure and activity.

artículo científico

Gastric pre-processing is an important determinant of the ability of medium-chain lipid solution formulations to enhance oral bioavailability in rats.

artículo científico publicado en 2013

Gel-Mediated Electrospray Assembly of Silica Supraparticles for Sustained Drug Delivery

artículo científico publicado en 2018

Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability.

artículo científico publicado en 2016

Human bioavailability of propranolol from a matrix-in-cylinder system with a HPMC-Gelucire core.

artículo científico publicado en 2005

Hyaluronic Acid Molecular Weight Determines Lung Clearance and Biodistribution after Instillation.

artículo científico publicado en 2016

Impact of Cremophor-EL and Polysorbate-80 on Digoxin Permeability across Rat Jejunum: Delineation of Thermodynamic and Transporter Related Events Using the Reciprocal Permeability Approach

artículo científico publicado en 2007

Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations

artículo científico publicado en 2018

Impact of surface derivatization of poly-L-lysine dendrimers with anionic arylsulfonate or succinate groups on intravenous pharmacokinetics and disposition.

artículo científico publicado en 2007

In vitro assessment of drug-free and fenofibrate-containing lipid formulations using dispersion and digestion testing gives detailed insights into the likely fate of formulations in the intestine

artículo científico publicado en 2013

In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products.

artículo científico publicado en 2012

In vitro-in vivo evaluation of lipid based formulations of the CETP inhibitors CP-529,414 (torcetrapib) and CP-532,623

artículo científico publicado en 2014

Incomplete Desorption of Liquid Excipients Reduces the in Vitro and in Vivo Performance of Self-Emulsifying Drug Delivery Systems Solidified by Adsorption onto an Inorganic Mesoporous Carrier

artículo científico publicado en 2012

Increasing the proportional content of surfactant (Cremophor EL) relative to lipid in self-emulsifying lipid-based formulations of danazol reduces oral bioavailability in beagle dogs

scientific article published on 15 February 2007

Influence of the intermediate digestion phases of common formulation lipids on the absorption of a poorly water-soluble drug.

artículo científico publicado en 2005

Intestinal bile secretion promotes drug absorption from lipid colloidal phases via induction of supersaturation

artículo científico publicado en 2013

Intestinal lymphatic transport enhances the post-prandial oral bioavailability of a novel cannabinoid receptor agonist via avoidance of first-pass metabolism.

artículo científico publicado en 2009

Intestinal lymphatic transport of halofantrine occurs after oral administration of a unit-dose lipid-based formulation to fasted dogs

artículo científico publicado el 1 de septiembre de 2003

Intravenous dosing conditions may affect systemic clearance for highly lipophilic drugs: implications for lymphatic transport and absolute bioavailability studies.

artículo científico publicado en 2012

Ionic Liquid Forms of Weakly Acidic Drugs in Oral Lipid Formulations: Preparation, Characterization, in Vitro Digestion, and in Vivo Absorption Studies.

artículo científico publicado en 2017

Ionic Liquid Forms of the Antimalarial Lumefantrine in Combination with LFCS Type IIIB Lipid-Based Formulations Preferentially Increase Lipid Solubility, In Vitro Solubilization Behavior and In Vivo Exposure

artículo científico publicado en 2019

Ionic liquids provide unique opportunities for oral drug delivery: structure optimization and in vivo evidence of utility

artículo científico publicado en 2014

Lipid absorption triggers drug supersaturation at the intestinal unstirred water layer and promotes drug absorption from mixed micelles

artículo científico publicado en 2013

Lipid-Based Formulations Solidified Via Adsorption onto the Mesoporous Carrier Neusilin® US2: Effect of Drug Type and Formulation Composition on In Vitro Pharmaceutical Performance

article

Lipid-based formulations and drug supersaturation: harnessing the unique benefits of the lipid digestion/absorption pathway.

artículo científico

Lipid-based formulations for oral administration: opportunities for bioavailability enhancement and lipoprotein targeting of lipophilic drugs

artículo científico publicado en 2001

Lipid-based systems for the enhanced delivery of poorly water soluble drugs

Lipids in the Stomach - Implications for the Evaluation of Food Effects on Oral Drug Absorption

artículo científico publicado en 2018

Low dose lipid formulations: effects on gastric emptying and biliary secretion

artículo científico publicado en 2007

Lymphatic Absorption of Subcutaneously Administered Proteins: Influence of Different Injection Sites on the Absorption of Darbepoetin Alfa Using a Sheep Model

article

Lymphatic Uptake of Liposomes after Intraperitoneal Administration Primarily Occurs via the Diaphragmatic Lymphatics and is Dependent on Liposome Surface Properties

scientific article published on 01 November 2019

Lymphatic absorption is the primary contributor to the systemic availability of epoetin Alfa following subcutaneous administration to sheep.

artículo científico publicado en 2004

Lymphatic transport of Methylnortestosterone undecanoate (MU) and the bioavailability of methylnortestosterone are highly sensitive to the mass of coadministered lipid after oral administration of MU.

artículo científico publicado en 2009

Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous administration in rats

artículo científico publicado en 2015

Minimum information reporting in bio-nano experimental literature

artículo científico publicado en 2018

Molecular weight (hydrodynamic volume) dictates the systemic pharmacokinetics and tumour disposition of PolyPEG star polymers.

artículo científico publicado en 2015

Nano-chemotherapeutics: maximising lymphatic drug exposure to improve the treatment of lymph-metastatic cancers.

artículo científico

Nanostructured liquid crystalline particles provide long duration sustained-release effect for a poorly water soluble drug after oral administration

scientific article published on 08 April 2011

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

artículo científico publicado en 2017

Non-linear increases in danazol exposure with dose in older vs. younger beagle dogs: the potential role of differences in bile salt concentration, thermodynamic activity, and formulation digestion

artículo científico publicado en 2014

Optimal PEGylation can improve the exposure of interferon in the lungs following pulmonary administration

artículo científico publicado en 2015

Oral bioavailability assessment and intestinal lymphatic transport of Org 45697 and Org 46035, two highly lipophilic novel immunomodulator analogues.

artículo científico publicado en 2009

PEGylation does not significantly change the initial intravenous or subcutaneous pharmacokinetics or lymphatic exposure of trastuzumab in rats but increases plasma clearance after subcutaneous administration.

artículo científico publicado en 2015

PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastases.

artículo científico publicado en 2013

Permeability assessment of poorly water-soluble compounds under solubilizing conditions: the reciprocal permeability approach.

artículo científico publicado en 2006

Pharmacokinetics and Tumor Disposition of PEGylated, Methotrexate Conjugated Poly-l-lysine Dendrimers

artículo científico publicado en 2009

Pharmacokinetics of recombinant human leukemia inhibitory factor in sheep.

artículo científico publicado en 2004

Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water soluble drugs I. Phase behaviour in physiologically-relevant media

Pluronic-Functionalized Silica-Lipid Hybrid Microparticles: Improving the Oral Delivery of Poorly Water-Soluble Weak Bases.

artículo científico publicado en 2015

Pointing in the Right Direction: Controlling the Orientation of Proteins on Nanoparticles Improves Targeting Efficiency

scientific article published on 21 February 2019

Polymeric Nanotubes as Drug Delivery Vectors─Comparison of Covalently and Supramolecularly Assembled Constructs

artículo científico publicado en 2022

Polymeric Precipitation Inhibitors Promote Fenofibrate Supersaturation and Enhance Drug Absorption from a Type IV Lipid-Based Formulation.

artículo científico publicado en 2018

Population pharmacokinetics of colistin methanesulfonate in rats: achieving sustained lung concentrations of colistin for targeting respiratory infections.

artículo científico publicado en 2013

Preparation, crystallization and preliminary X-ray diffraction analysis of two intestinal fatty-acid binding proteins in the presence of 11-(dansylamino)undecanoic acid

artículo científico publicado en 2011

Probing drug solubilization patterns in the gastrointestinal tract after administration of lipid-based delivery systems: a phase diagram approach.

artículo científico publicado en 2004

Probing the fibrate binding specificity of rat liver fatty acid binding protein.

artículo científico publicado en 2009

Profiling the role of deacylation-reacylation in the lymphatic transport of a triglyceride-mimetic prodrug

artículo científico publicado en 2014

Promoting intestinal lymphatic transport targets a liver-X receptor (LXR) agonist (WAY-252,623) to lymphocytes and enhances immunomodulation

artículo científico publicado en 2019

Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome

article published in the Proceedings of the National Academy of Sciences of the United States of America

Pulmonary administration of a doxorubicin-conjugated dendrimer enhances drug exposure to lung metastases and improves cancer therapy

scientific article published on 14 March 2014

Pulmonary and systemic pharmacokinetics of inhaled and intravenous colistin methanesulfonate in cystic fibrosis patients: targeting advantage of inhalational administration.

artículo científico publicado en 2014

Quantifying In Vivo Luminal Drug Solubilization -Supersaturation-Precipitation Profiles to Explain the Performance of Lipid Based Formulations

artículo científico publicado en 2020

Recent advances in lipid-based formulation technology.

artículo científico publicado en 2013

Reduced blood-brain barrier expression of fatty acid-binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega-3 fatty acid diets

artículo científico publicado en 2017

Reducing Dendrimer Generation and PEG Chain Length Increases Drug Release and Promotes Anticancer Activity of PEGylated Polylysine Dendrimers Conjugated with Doxorubicin via a Cathepsin-Cleavable Peptide Linker

artículo científico publicado en 2018

Removal of interstitial hyaluronan with recombinant human hyaluronidase improves the systemic and lymphatic uptake of cetuximab in rats

scientific article published on 23 October 2019

Separation and characterization of the colloidal phases produced on digestion of common formulation lipids and assessment of their impact on the apparent solubility of selected poorly water-soluble drugs.

artículo científico publicado en 2003

Silica-lipid hybrid (SLH) formulations enhance the oral bioavailability and efficacy of celecoxib: An in vivo evaluation.

artículo científico publicado en 2013

Size and rigidity of cylindrical polymer brushes dictate long circulating properties in vivo

artículo científico publicado en 2015

Subcutaneous drug delivery and the role of the lymphatics

artículo científico publicado en 2005

Targeted delivery of a model immunomodulator to the lymphatic system: comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies

artículo científico publicado en 2014

Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?

artículo científico publicado en 2010

Targeting immune cells within lymph nodes

artículo científico publicado en 2020

Targeting the lymphatics using dendritic polymers (dendrimers).

artículo científico publicado en 2011

The Lymphatic System Plays a Major Role in the Intravenous and Subcutaneous Pharmacokinetics of Trastuzumab in Rats

artículo científico publicado en 2014

The Pharmacokinetics and Biodistribution of a 64 kDa PolyPEG Star Polymer After Subcutaneous and Pulmonary Administration to Rats

artículo científico publicado en 2016

The Role of the Intestinal Lymphatics in the Absorption of Two Highly Lipophilic Cholesterol Ester Transfer Protein Inhibitors (CP524,515 and CP532,623)

artículo científico publicado en 2010

The absorption of darbepoetin alfa occurs predominantly via the lymphatics following subcutaneous administration to sheep.

artículo científico publicado en 2006

The effect of administered dose of lipid-based formulations on the in vitro and in vivo performance of cinnarizine as a model poorly water-soluble drug.

artículo científico publicado en 2012

The impact of P-glycoprotein efflux on enterocyte residence time and enterocyte-based metabolism of verapamil.

artículo científico publicado en 2001

The impact of lymphatic transport on the systemic disposition of lipophilic drugs.

artículo científico publicado en 2013

The influence of intestinal lymphatic transport on the systemic exposure and brain deposition of a novel highly lipophilic compound with structural similarity to cholesterol

scientific article published on 12 May 2014

The interaction of lipophilic drugs with intestinal fatty acid-binding protein.

artículo científico publicado en 2005

The lymph lipid precursor pool is a key determinant of intestinal lymphatic drug transport.

artículo científico publicado en 2005

The mechanism of lymphatic access of two cholesteryl ester transfer protein inhibitors (CP524,515 and CP532,623) and evaluation of their impact on lymph lipoprotein profiles

artículo científico publicado en 2010

The mesenteric lymph duct cannulated rat model: application to the assessment of intestinal lymphatic drug transport

artículo científico publicado en 2015

The potential for drug supersaturation during intestinal processing of lipid-based formulations may be enhanced for basic drugs

artículo científico publicado en 2013

Tools for Early Prediction of Drug Loading in Lipid-Based Formulations.

artículo científico publicado en 2015

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations

artículo científico publicado en 2012

Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion

scientific article published on 22 October 2012

Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations.

artículo científico publicado en 2013

Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system

artículo científico publicado en 2014

Toward the establishment of standardized in vitro tests for lipid-based formulations. 5. Lipolysis of representative formulations by gastric lipase.

artículo científico publicado en 2014

Transformation of Biopharmaceutical Classification System Class I and III Drugs Into Ionic Liquids and Lipophilic Salts for Enhanced Developability Using Lipid Formulations.

artículo científico publicado en 2017

Transformation of poorly water-soluble drugs into lipophilic ionic liquids enhances oral drug exposure from lipid based formulations

artículo científico publicado en 2015

Transient Supersaturation Supports Drug Absorption from Lipid-Based Formulations for Short Periods of Time, but Ongoing Solubilization Is Required for Longer Absorption Periods.

artículo científico publicado en 2016

Understanding the Challenge of Beyond-Rule-of-5 Compounds.

artículo científico publicado en 2016

Use of in vitro lipid digestion data to explain the in vivo performance of triglyceride-based oral lipid formulations of poorly water-soluble drugs: studies with halofantrine.

artículo científico publicado en 2004

Using polymeric precipitation inhibitors to improve the absorption of poorly water-soluble drugs: A mechanistic basis for utility.

artículo científico publicado en 2010

Using the polymer partitioning method to probe the thermodynamic activity of poorly water-soluble drugs solubilized in model lipid digestion products.

artículo científico publicado en 2003