Lista de obras - Lyle Armstrong - Dominio Público Uruguay

A Novel Role for miR-1305 in Regulation of Pluripotency-Differentiation Balance, Cell Cycle, and Apoptosis in Human Pluripotent Stem Cells

artículo científico publicado en 2016

A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs.

artículo científico publicado en 2017

A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors.

artículo científico publicado en 2013

A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells

artículo científico publicado en 2013

A putative role for the immunoproteasome in the maintenance of pluripotency in human embryonic stem cells.

artículo científico publicado en 2012

Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells.

artículo científico publicado en 2008

Aging of Stem and Progenitor Cells: Mechanisms, Impact on Therapeutic Potential, and Rejuvenation

artículo científico

An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure. ⬇️

artículo científico publicado en 2017

An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells.

artículo científico publicado en 2005

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells

artículo científico publicado en 2011

Brief Report: Inhibition of miR-145 Enhances Reprogramming of Human Dermal Fibroblasts to Induced Pluripotent Stem Cells.

artículo científico publicado en 2015

Brief report: human pluripotent stem cell models of fanconi anemia deficiency reveal an important role for fanconi anemia proteins in cellular reprogramming and survival of hematopoietic progenitors.

artículo científico publicado en 2013

Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: role of Wnt3 in enhancing haematopoietic differentiation.

artículo científico publicado en 2001

Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of age-related macular degeneration by restoring lysosomal function

artículo científico publicado en 2020

Concise Review: Cardiac Disease Modeling Using Induced Pluripotent Stem Cells.

artículo científico

Concise Review: Getting to the Core of Inherited Bone Marrow Failures.

artículo científico publicado en 2017

Concise review: the epigenetic contribution to stem cell ageing: can we rejuvenate our older cells?

artículo científico

Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease

artículo científico publicado en 2012

Differences in the Activity of Endogenous Bone Morphogenetic Protein Signaling Impact on the Ability of Induced Pluripotent Stem Cells to Differentiate to Corneal Epithelial-Like Cells.

artículo científico publicado en 2017

Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa ⬇️

artículo científico publicado en 2018

Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages

artículo científico publicado en 2005

Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells

artículo científico publicado en 2007

Editorial: Our top 10 developments in stem cell biology over the last 30 years

artículo científico publicado en 2012

Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.

artículo científico publicado en 2008

Engraftment's Holy Grail: is one signal enough?

artículo científico publicado en 2014

Epigenetic control of embryonic stem cell differentiation.

artículo científico

Epigenetic landscaping during hESC differentiation to neural cells.

artículo científico publicado en 2009

Epigenetic marking prepares the human HOXA cluster for activation during differentiation of pluripotent cells.

artículo científico publicado en 2008

Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer.

artículo científico publicado en 2005

Ethical and Safety Issues of Stem Cell-Based Therapy.

artículo científico publicado en 2018

Expression of GFP under the control of the RNA helicase VASA permits fluorescence-activated cell sorting isolation of human primordial germ cells.

artículo científico publicado en 2010

Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells

scholarly article by Minjin Jeong et al published 11 September 2018 in Cell Death and Disease

Generation of Human Induced Pluripotent Stem Cells Using RNA-Based Sendai Virus System and Pluripotency Validation of the Resulting Cell Population

artículo científico publicado en 2015

Hepatic differentiation of human iPSCs in different 3D models: A comparative study.

artículo científico publicado en 2017

Human embryonic stem cells: biology and clinical implications.

artículo científico publicado en 2005

Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- and method-dependent

artículo científico publicado en 2019

Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A > G mitochondrial DNA mutation.

artículo científico publicado en 2017

Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells

artículo científico publicado en 2010

Human-Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient-Dependent Efficiency

scientific article published on 13 August 2018

Induced pluripotent stem cell modelling of HLHS underlines the contribution of dysfunctional NOTCH signalling to impaired cardiogenesis

artículo científico publicado en 2017

Induced pluripotent stem cells : it looks simple but can looks deceive?

artículo científico publicado en 2010

Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations

scientific article published on 09 August 2019

Isolation of primordial germ cells from differentiating human embryonic stem cells

artículo científico publicado en 2008

JNK/SAPK Signaling Is Essential for Efficient Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells

artículo científico publicado en 2016

Law should recognize value of interspecies embryos

artículo científico publicado en 2008

Multiplex High-Throughput Targeted Proteomic Assay To Identify Induced Pluripotent Stem Cells

artículo científico publicado en 2017

Nanog regulates primordial germ cell migration through Cxcr4b.

artículo científico publicado en 2010

Non-invasive imaging of stem cells by scanning ion conductance microscopy: future perspective

artículo científico publicado en 2008

Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage.

artículo científico publicado en 2005

Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity.

artículo científico publicado en 2004

Platform to study intracellular polystyrene nanoplastic pollution and clinical outcomes

artículo científico publicado en 2020

Pluripotent Stem Cell-Derived Hematopoietic Progenitors Are Unable to Downregulate Key Epithelial-Mesenchymal Transition-Associated miRNAs.

artículo científico publicado en 2017

Potential for pharmacological manipulation of human embryonic stem cells.

artículo científico

Primordial Germ Cells: Current Knowledge and Perspectives

artículo científico publicado en 2016

Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience

artículo científico publicado en 2017

Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study

article

Response to letter by Hallam et al.

artículo científico publicado en 2018

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

artículo científico publicado en 2011

Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells

scientific article published on 01 July 2008

The future of human nuclear transfer?

artículo científico publicado en 2006

The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages.

artículo científico publicado en 2016

The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis.

artículo científico publicado en 2006

Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion.

artículo científico publicado en 2017

iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors

artículo científico publicado en 2018

mTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cells.

artículo científico publicado en 2000

Lista de obras de Lyle Armstrong

A Novel Role for miR-1305 in Regulation of Pluripotency-Differentiation Balance, Cell Cycle, and Apoptosis in Human Pluripotent Stem Cells

A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs.

A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors.

A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells

A putative role for the immunoproteasome in the maintenance of pluripotency in human embryonic stem cells.

Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells.

Aging of Stem and Progenitor Cells: Mechanisms, Impact on Therapeutic Potential, and Rejuvenation

An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure. ⬇️

An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells.

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells

Brief Report: Inhibition of miR-145 Enhances Reprogramming of Human Dermal Fibroblasts to Induced Pluripotent Stem Cells.

Brief report: human pluripotent stem cell models of fanconi anemia deficiency reveal an important role for fanconi anemia proteins in cellular reprogramming and survival of hematopoietic progenitors.

Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: role of Wnt3 in enhancing haematopoietic differentiation.

Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of age-related macular degeneration by restoring lysosomal function

Concise Review: Cardiac Disease Modeling Using Induced Pluripotent Stem Cells.

Concise Review: Getting to the Core of Inherited Bone Marrow Failures.

Concise review: the epigenetic contribution to stem cell ageing: can we rejuvenate our older cells?

Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease

Differences in the Activity of Endogenous Bone Morphogenetic Protein Signaling Impact on the Ability of Induced Pluripotent Stem Cells to Differentiate to Corneal Epithelial-Like Cells.

Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa ⬇️

Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages

Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells

Editorial: Our top 10 developments in stem cell biology over the last 30 years

Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.

Engraftment's Holy Grail: is one signal enough?

Epigenetic control of embryonic stem cell differentiation.

Epigenetic landscaping during hESC differentiation to neural cells.

Epigenetic marking prepares the human HOXA cluster for activation during differentiation of pluripotent cells.

Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer.

Ethical and Safety Issues of Stem Cell-Based Therapy.

Expression of GFP under the control of the RNA helicase VASA permits fluorescence-activated cell sorting isolation of human primordial germ cells.

Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells

Generation of Human Induced Pluripotent Stem Cells Using RNA-Based Sendai Virus System and Pluripotency Validation of the Resulting Cell Population

Hepatic differentiation of human iPSCs in different 3D models: A comparative study.

Human embryonic stem cells: biology and clinical implications.

Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- and method-dependent

Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A > G mitochondrial DNA mutation.

Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells

Human-Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient-Dependent Efficiency

Induced pluripotent stem cell modelling of HLHS underlines the contribution of dysfunctional NOTCH signalling to impaired cardiogenesis

Induced pluripotent stem cells : it looks simple but can looks deceive?

Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations

Isolation of primordial germ cells from differentiating human embryonic stem cells

JNK/SAPK Signaling Is Essential for Efficient Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells

Law should recognize value of interspecies embryos

Multiplex High-Throughput Targeted Proteomic Assay To Identify Induced Pluripotent Stem Cells

Nanog regulates primordial germ cell migration through Cxcr4b.

Non-invasive imaging of stem cells by scanning ion conductance microscopy: future perspective

Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage.

Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity.

Platform to study intracellular polystyrene nanoplastic pollution and clinical outcomes

Pluripotent Stem Cell-Derived Hematopoietic Progenitors Are Unable to Downregulate Key Epithelial-Mesenchymal Transition-Associated miRNAs.

Potential for pharmacological manipulation of human embryonic stem cells.

Primordial Germ Cells: Current Knowledge and Perspectives

Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience

Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study

Response to letter by Hallam et al.

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells

The future of human nuclear transfer?

The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages.

The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis.

Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion.

iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors

mTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cells.