Lista de obras - Lene Jorgensen - Dominio Público Uruguay

Adsorption of insulin with varying self-association profiles to a solid Teflon surface--influence on protein structure, fibrillation tendency and thermal stability.

artículo científico publicado en 2011

Alternative routes of administration for systemic delivery of protein pharmaceuticals

artículo científico publicado en 2008

Biodegradable nanocomposite microparticles as drug delivering injectable cell scaffolds

artículo científico publicado en 2011

Calcipotriol delivery into the skin with PEGylated liposomes

scientific article published on 19 April 2012

Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces

artículo científico publicado en 2014

Complex coacervates of hyaluronic acid and lysozyme: effect on protein structure and physical stability.

artículo científico publicado en 2014

Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme.

artículo científico publicado en 2017

Delivery of Dermatan Sulfate from Polyelectrolyte Complex-Containing Alginate Composite Microspheres for Tissue Regeneration

artículo científico publicado en 2012

Design and characterization of core-shell mPEG-PLGA composite microparticles for development of cell-scaffold constructs

artículo científico publicado en 2013

Design and processing of nanogels as delivery systems for peptides and proteins.

artículo científico

Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin α₂β₁ receptor.

artículo científico publicado en 2012

Determination of liposome-buffer distribution coefficients of charged drugs by capillary electrophoresis frontal analysis.

artículo científico publicado en 2009

Drug-liposome distribution phenomena studied by capillary electrophoresis-frontal analysis.

artículo científico publicado en 2008

Elucidating the mechanisms of protein antigen adsorption to the CAF/NAF liposomal vaccine adjuvant systems: effect of charge, fluidity and antigen-to-lipid ratio.

artículo científico publicado en 2014

Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces

artículo científico publicado en 2012

Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

artículo científico publicado en 2010

Influence of PEGylation with linear and branched PEG chains on the adsorption of glucagon to hydrophobic surfaces

artículo científico publicado en 2010

Influence of acylation on the adsorption of GLP-2 to hydrophobic surfaces ⬇️

artículo científico publicado el 28 de enero de 2012

Influence of acylation on the adsorption of insulin to hydrophobic surfaces

scientific article published on 29 December 2010

Influence of glycosylation on the adsorption of Thermomyces lanuginosus lipase to hydrophobic and hydrophilic surfaces.

artículo científico publicado en 2010

Interaction of Peptidomimetics with Bilayer Membranes: Biophysical Characterization and Cellular Uptake

artículo científico publicado en 2012

Interfacial Complexes between a Protein and Lipophilic Ions at an Oil−Water Interface

artículo científico publicado en 2010

Interfacial adsorption of insulin conformational changes and reversibility of adsorption.

artículo científico publicado en 2005

Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601

artículo científico publicado en 2015

Kinetics of insulin adsorption at the oil-water interface and diffusion properties of adsorbed layers monitored using fluorescence correlation spectroscopy.

artículo científico publicado en 2006

Lipidation Effect on Surface Adsorption and Associated Fibrillation of the Model Protein Insulin.

artículo científico publicado en 2016

Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation.

artículo científico publicado en 2016

Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: Effects of hydrogen bonding and α-chirality in the β-peptoid residues

artículo científico publicado en 2012

Micropipette manipulation: a technique to evaluate the stability of water-in-oil emulsions containing proteins

artículo científico publicado en 2004

Preparing and evaluating delivery systems for proteins.

artículo científico publicado en 2006

Probing insulin’s secondary structure after entrapment into alginate/chitosan nanoparticles

scientific article published on 24 September 2006

Probing structural changes of proteins incorporated into water-in-oil emulsions.

artículo científico publicado en 2004

Protein Adsorption at Charged Surfaces: The Role of Electrostatic Interactions and Interfacial Charge Regulation

artículo científico publicado en 2011

Protein adsorption and displacement at lipid layers determined by total internal reflection fluorescence (TIRF).

artículo científico publicado en 2009

Protein adsorption to poly(tetrafluoroethylene) membranes modified with grafted poly(acrylic acid) chains

artículo científico publicado en 2020

Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients.

artículo científico publicado en 2009

Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity.

artículo científico publicado en 2017

Simple measurements for prediction of drug release from polymer matrices – Solubility parameters and intrinsic viscosity

artículo científico publicado en 2015

Studies on human insulin adsorption kinetics at an organic–aqueous interface determined using a label-free electroanalytical approach

artículo científico publicado en 2007

Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery

scientific article published on 12 March 2017

Targeting of liposome-associated calcipotriol to the skin: Effect of liposomal membrane fluidity and skin barrier integrity

artículo científico publicado en 2011

The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products--A Study Using Aloin and Insulin

artículo científico publicado en 2016

The importance of interfaces in protein drug delivery - why is protein adsorption of interest in pharmaceutical formulations?

artículo científico publicado en 2011

The influence of size, structure and hydrophilicity of model surfactants on the adsorption of lysozyme to oil–water interface—Interfacial shear measurements ⬇️

artículo científico publicado el 10 de mayo de 2011

The physical stability of the recombinant tuberculosis fusion antigens h1 and h56.

artículo científico publicado en 2013

Lista de obras de Lene Jorgensen

Adsorption of insulin with varying self-association profiles to a solid Teflon surface--influence on protein structure, fibrillation tendency and thermal stability.

Alternative routes of administration for systemic delivery of protein pharmaceuticals

Biodegradable nanocomposite microparticles as drug delivering injectable cell scaffolds

Calcipotriol delivery into the skin with PEGylated liposomes

Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces

Complex coacervates of hyaluronic acid and lysozyme: effect on protein structure and physical stability.

Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme.

Delivery of Dermatan Sulfate from Polyelectrolyte Complex-Containing Alginate Composite Microspheres for Tissue Regeneration

Design and characterization of core-shell mPEG-PLGA composite microparticles for development of cell-scaffold constructs

Design and processing of nanogels as delivery systems for peptides and proteins.

Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin α₂β₁ receptor.

Determination of liposome-buffer distribution coefficients of charged drugs by capillary electrophoresis frontal analysis.

Drug-liposome distribution phenomena studied by capillary electrophoresis-frontal analysis.

Elucidating the mechanisms of protein antigen adsorption to the CAF/NAF liposomal vaccine adjuvant systems: effect of charge, fluidity and antigen-to-lipid ratio.

Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces

Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

Influence of PEGylation with linear and branched PEG chains on the adsorption of glucagon to hydrophobic surfaces

Influence of acylation on the adsorption of GLP-2 to hydrophobic surfaces ⬇️

Influence of acylation on the adsorption of insulin to hydrophobic surfaces

Influence of glycosylation on the adsorption of Thermomyces lanuginosus lipase to hydrophobic and hydrophilic surfaces.

Interaction of Peptidomimetics with Bilayer Membranes: Biophysical Characterization and Cellular Uptake

Interfacial Complexes between a Protein and Lipophilic Ions at an Oil−Water Interface

Interfacial adsorption of insulin conformational changes and reversibility of adsorption.

Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601

Kinetics of insulin adsorption at the oil-water interface and diffusion properties of adsorbed layers monitored using fluorescence correlation spectroscopy.

Lipidation Effect on Surface Adsorption and Associated Fibrillation of the Model Protein Insulin.

Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation.

Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: Effects of hydrogen bonding and α-chirality in the β-peptoid residues

Micropipette manipulation: a technique to evaluate the stability of water-in-oil emulsions containing proteins

Preparing and evaluating delivery systems for proteins.

Probing insulin’s secondary structure after entrapment into alginate/chitosan nanoparticles

Probing structural changes of proteins incorporated into water-in-oil emulsions.

Protein Adsorption at Charged Surfaces: The Role of Electrostatic Interactions and Interfacial Charge Regulation

Protein adsorption and displacement at lipid layers determined by total internal reflection fluorescence (TIRF).

Protein adsorption to poly(tetrafluoroethylene) membranes modified with grafted poly(acrylic acid) chains

Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients.

Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity.

Simple measurements for prediction of drug release from polymer matrices – Solubility parameters and intrinsic viscosity

Studies on human insulin adsorption kinetics at an organic–aqueous interface determined using a label-free electroanalytical approach

Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery

Targeting of liposome-associated calcipotriol to the skin: Effect of liposomal membrane fluidity and skin barrier integrity

The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products--A Study Using Aloin and Insulin

The importance of interfaces in protein drug delivery - why is protein adsorption of interest in pharmaceutical formulations?

The influence of size, structure and hydrophilicity of model surfactants on the adsorption of lysozyme to oil–water interface—Interfacial shear measurements ⬇️

The physical stability of the recombinant tuberculosis fusion antigens h1 and h56.