Lista de obras - Bob Asselbergh - Dominio Público Uruguay

A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.

artículo científico

A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins

artículo científico publicado en 2021

Abscisic acid deficiency causes changes in cuticle permeability and pectin composition that influence tomato resistance to Botrytis cinerea

artículo científico publicado en 2010

Abscisic acid deficiency leads to rapid activation of tomato defence responses upon infection with Erwinia chrysanthemi

artículo científico publicado en 2008

Acute injury in the peripheral nervous system triggers an alternative macrophage response.

artículo científico publicado en 2012

CMT-associated mutations in glycyl- and tyrosyl-tRNA synthetases exhibit similar pattern of toxicity and share common genetic modifiers in Drosophila

artículo científico publicado en 2014

Caspase-14-deficient mice are more prone to the development of parakeratosis

artículo científico publicado en 2012

Characterization of two mutations in the SPTLC1 subunit of serine palmitoyltransferase associated with hereditary sensory and autonomic neuropathy type I.

artículo científico publicado en 2011

Charcot-Marie-Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments

scientific journal article

Developing 3D SEM in a broad biological context

artículo científico publicado en 2015

Diffusion kurtosis imaging to detect amyloidosis in an APP/PS1 mouse model for Alzheimer's disease.

artículo científico publicado en 2013

Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis

artículo científico publicado en 2011

Global switches and fine-tuning-ABA modulates plant pathogen defense

artículo científico publicado en 2008

HSPB1 facilitates the formation of non-centrosomal microtubules

artículo científico publicado en 2013

Human Rab7 mutation mimics features of Charcot-Marie-Tooth neuropathy type 2B in Drosophila

artículo científico publicado en 2014

Inhibition of spontaneous neutrophil apoptosis by parabutoporin acts independently of NADPH oxidase inhibition but by lipid raft-dependent stimulation of Akt.

artículo científico publicado en 2009

Mitochondria-associated membranes as hubs for neurodegeneration

artículo científico publicado en 2016

Molecular defects in the motor adaptor BICD2 cause proximal spinal muscular atrophy with autosomal-dominant inheritance

artículo científico publicado en 2013

Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease

artículo científico publicado en 2017

Mutant HSPB8 causes motor neuron-specific neurite degeneration.

artículo científico publicado en 2010

Mutant HSPB8 causes protein aggregates and a reduced mitochondrial membrane potential in dermal fibroblasts from distal hereditary motor neuropathy patients.

artículo científico publicado en 2012

Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies

article

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

artículo científico publicado en 2010

Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury

artículo científico publicado en 2020

Recessive mutations in SLC13A5 result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia

artículo científico publicado en 2015

Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations

artículo científico publicado en 2015

Resistance to Botrytis cinerea in sitiens, an abscisic acid-deficient tomato mutant, involves timely production of hydrogen peroxide and cell wall modifications in the epidermis

artículo científico publicado en 2007

Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy.

artículo científico publicado en 2011

Sphingosine 1-phosphate lyase deficiency causes Charcot-Marie-Tooth neuropathy.

artículo científico publicado en 2017

Lista de obras de Bob Asselbergh

A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.

A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins

Abscisic acid deficiency causes changes in cuticle permeability and pectin composition that influence tomato resistance to Botrytis cinerea

Abscisic acid deficiency leads to rapid activation of tomato defence responses upon infection with Erwinia chrysanthemi

Acute injury in the peripheral nervous system triggers an alternative macrophage response.

CMT-associated mutations in glycyl- and tyrosyl-tRNA synthetases exhibit similar pattern of toxicity and share common genetic modifiers in Drosophila

Caspase-14-deficient mice are more prone to the development of parakeratosis

Characterization of two mutations in the SPTLC1 subunit of serine palmitoyltransferase associated with hereditary sensory and autonomic neuropathy type I.

Charcot-Marie-Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments

Developing 3D SEM in a broad biological context

Diffusion kurtosis imaging to detect amyloidosis in an APP/PS1 mouse model for Alzheimer's disease.

Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis

Global switches and fine-tuning-ABA modulates plant pathogen defense

HSPB1 facilitates the formation of non-centrosomal microtubules

Human Rab7 mutation mimics features of Charcot-Marie-Tooth neuropathy type 2B in Drosophila

Inhibition of spontaneous neutrophil apoptosis by parabutoporin acts independently of NADPH oxidase inhibition but by lipid raft-dependent stimulation of Akt.

Mitochondria-associated membranes as hubs for neurodegeneration

Molecular defects in the motor adaptor BICD2 cause proximal spinal muscular atrophy with autosomal-dominant inheritance

Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease

Mutant HSPB8 causes motor neuron-specific neurite degeneration.

Mutant HSPB8 causes protein aggregates and a reduced mitochondrial membrane potential in dermal fibroblasts from distal hereditary motor neuropathy patients.

Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury

Recessive mutations in SLC13A5 result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia

Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations

Resistance to Botrytis cinerea in sitiens, an abscisic acid-deficient tomato mutant, involves timely production of hydrogen peroxide and cell wall modifications in the epidermis

Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy.

Sphingosine 1-phosphate lyase deficiency causes Charcot-Marie-Tooth neuropathy.