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Lista de obras de Romina Alfonsi

Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61.

artículo científico publicado en 2018

Design, Palladium-Catalyzed Synthesis, and Biological Investigation of 2-Substituted 3-Aroylquinolin-4(1H)-ones as Inhibitors of the Hedgehog Signaling Pathway.

artículo científico publicado en 2017

Diagnostic and prognostic potential of the proteomic profiling of serum-derived extracellular vesicles in prostate cancer

artículo científico publicado en 2021

Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.

artículo científico publicado en 2014

Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects.

artículo científico publicado en 2017

Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype

artículo científico publicado en 2016

Insights into Gli Factors Ubiquitylation Methods.

artículo científico publicado en 2015

Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.

artículo científico publicado en 2018

MK-4101, a Potent Inhibitor of the Hedgehog Pathway, Is Highly Active against Medulloblastoma and Basal Cell Carcinoma

artículo científico publicado en 2016

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

artículo científico publicado en 2015

New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer

artículo científico publicado en 2014

Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases

artículo científico publicado en 2019

PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress

artículo científico publicado en 2013

Renal cancer: new models and approach for personalizing therapy

artículo científico publicado en 2018

Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold

scientific article published on 09 July 2018

Targeting GLI factors to inhibit the Hedgehog pathway.

artículo científico

The Double Face of Exosome-Carried MicroRNAs in Cancer Immunomodulation.

artículo científico publicado en 2018