Lista de obras - David I Broadhurst - Dominio Público Uruguay

(1)H-NMR urinary metabolomic profiling for diagnosis of gastric cancer

artículo científico publicado en 2015

1H NMR Derived Metabolomic Profile of Neonatal Asphyxia in Umbilical Cord Serum: Implications for Hypoxic Ischemic Encephalopathy

scientific article published on 21 August 2013

A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols

artículo científico publicado en 2008

A comparative evaluation of the generalised predictive ability of eight machine learning algorithms across ten clinical metabolomics data sets for binary classification

artículo científico publicado en 2019

A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations

scientific article (publication date: 2001)

Angiogenic imbalance and plasma lipid alterations in women with preeclampsia from a developing country.

artículo científico publicado en 2012

Biomarkers of dietary energy restriction in women at increased risk of breast cancer.

artículo científico publicado en 2009

Changes in the metabolic footprint of placental explant-conditioned culture medium identifies metabolic disturbances related to hypoxia and pre-eclampsia.

artículo científico publicado en 2009

Characterizing the plasma metabolome during and following a maximal exercise cycling test

artículo científico publicado en 2018

Closed-loop, multiobjective optimization of two-dimensional gas chromatography/mass spectrometry for serum metabolomics

artículo científico publicado en 2007

Detection and identification of novel metabolomic biomarkers in preeclampsia

artículo científico publicado en 2008

Development and Performance of a Gas Chromatography−Time-of-Flight Mass Spectrometry Analysis for Large-Scale Nontargeted Metabolomic Studies of Human Serum

article

Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum

artículo científico publicado en 2009

Direct infusion mass spectrometry metabolomics dataset: a benchmark for data processing and quality control

artículo científico publicado en 2014

Discrimination of modes of action of antifungal substances by use of metabolic footprinting.

artículo científico publicado en 2004

Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC-MS based untargeted metabolomics practitioners

artículo científico publicado en 2020

Does exercise impact gut microbiota composition in men receiving androgen deprivation therapy for prostate cancer? A single-blinded, two-armed, randomised controlled trial

article

Early Cord Metabolite Index and Outcome in Perinatal Asphyxia and Hypoxic-Ischaemic Encephalopathy

artículo científico publicado en 2016

Evidence that multiple defects in lipid regulation occur before hyperglycemia during the prodrome of type-2 diabetes.

artículo científico publicado en 2014

Explanatory Optimization of Protein Mass Spectrometry via Genetic Search

artículo científico publicado en 2003

Exploring the mode of action of dithranol therapy for psoriasis: a metabolomic analysis using HaCaT cells

artículo científico publicado en 2015

Functional genomics via metabolic footprinting: monitoring metabolite secretion by Escherichia coli tryptophan metabolism mutants using FT-IR and direct injection electrospray mass spectrometry

artículo científico publicado en 2003

Genetic algorithms as a method for variable selection in multiple linear regression and partial least squares regression, with applications to pyrolysis mass spectrometry

scholarly article by David I Broadhurst et al published August 1997 in Analytica Chimica Acta

Gestation-specific D-dimer reference ranges: a cross-sectional study

artículo científico publicado en 2014

Global metabolic profiling of Escherichia coli cultures: an evaluation of methods for quenching and extraction of intracellular metabolites.

artículo científico publicado en 2008

Growth control of the eukaryote cell: a systems biology study in yeast ⬇️

artículo científico publicado en 2007

Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies.

artículo científico publicado en 2018

High-throughput classification of yeast mutants for functional genomics using metabolic footprinting.

artículo científico publicado en 2003

High-throughput metabolic fingerprinting of legume silage fermentations via Fourier transform infrared spectroscopy and chemometrics

artículo científico publicado en 2004

Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles

artículo científico publicado en 2006

Improvement in the Prediction of Neonatal Hypoxicischemic Encephalopathy with the Integration of Umbilical Cord Metabolites and Current Clinical Makers

artículo científico publicado en 2020

Macronutrient Regulation of Ghrelin and Peptide YY in Pediatric Obesity and Prader-Willi Syndrome

artículo científico publicado en 2015

Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics

artículo científico publicado en 2009

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

artículo científico publicado en 2012

Metabolic profiling of serum using Ultra Performance Liquid Chromatography and the LTQ-Orbitrap mass spectrometry system

artículo científico publicado en 2008

Metabolic profiling uncovers a phenotypic signature of small for gestational age in early pregnancy

artículo científico publicado en 2011

Metabolomic profiling in multiple sclerosis: insights into biomarkers and pathogenesis

artículo científico publicado en 2014

Metabolomics enables precision medicine: "A White Paper, Community Perspective"

artículo científico publicado en 2016

Metabolomics reveals the physiological response of Pseudomonas putida KT2440 (UWC1) after pharmaceutical exposure

artículo científico publicado en 2016

Migrating from PLS to Artificial Neural Networks - Adapting Interpretation Strategies

poster

Migrating from partial least squares discriminant analysis to artificial neural networks: a comparison of functionally equivalent visualisation and feature contribution tools using jupyter notebooks

scientific article published on 21 January 2020

Molecular phenotyping of a UK population: defining the human serum metabolome

artículo científico publicado en 2015

Monitoring of complex industrial bioprocesses for metabolite concentrations using modern spectroscopies and machine learning: application to gibberellic acid production

artículo científico publicado en 2002

On the statistics of identifying candidate pathogen effectors

artículo científico publicado en 2014

OnPLS-Based Multi-Block Data Integration: A Multivariate Approach to Interrogating Biological Interactions in Asthma

artículo científico publicado en 2018

PYCHEM: a multivariate analysis package for python

artículo científico publicado en 2006

Perinatal determinants of D-dimer levels in a cross-sectional study of low risk pregnant women

artículo científico publicado en 2016

Preanalytical Processing and Biobanking Procedures of Biological Samples for Metabolomics Research: A White Paper, Community Perspective (for “Precision Medicine and Pharmacometabolomics Task Group”—The Metabolomics Society Initiative)

artículo científico publicado en 2018

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

article

Proposed minimum reporting standards for data analysis in metabolomics

article

Rapid and quantitative detection of the microbial spoilage of meat by fourier transform infrared spectroscopy and machine learning

artículo científico publicado en 2002

Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

artículo científico publicado en 2014

Robust early pregnancy prediction of later preeclampsia using metabolomic biomarkers

artículo científico publicado en 2010

Sildenafil Therapy Normalizes the Aberrant Metabolomic Profile in the Comt(-/-) Mouse Model of Preeclampsia/Fetal Growth Restriction

artículo científico publicado en 2015

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

artículo científico publicado en 2010

The application of artificial neural networks in metabolomics: a historical perspective

artículo científico publicado en 2019

The effect of haemolysis on the metabolomic profile of umbilical cord blood

artículo científico publicado en 2015

The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans

artículo científico

The metabolomic profile of umbilical cord blood in neonatal hypoxic ischaemic encephalopathy

artículo científico publicado en 2012

Toward collaborative open data science in metabolomics using Jupyter Notebooks and cloud computing

artículo científico publicado en 2019

Towards quality assurance and quality control in untargeted metabolomics studies

artículo científico publicado en 2019

Translational biomarker discovery in clinical metabolomics: an introductory tutorial

artículo científico publicado en 2013

Untargeted metabolomic analysis and pathway discovery in perinatal asphyxia and hypoxic-ischaemic encephalopathy.

artículo científico publicado en 2017

Using metabolic fingerprinting of plants for evaluating nitrogen deposition impacts on the landscape level

article

Lista de obras de David I Broadhurst

(1)H-NMR urinary metabolomic profiling for diagnosis of gastric cancer

1H NMR Derived Metabolomic Profile of Neonatal Asphyxia in Umbilical Cord Serum: Implications for Hypoxic Ischemic Encephalopathy

A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols

A comparative evaluation of the generalised predictive ability of eight machine learning algorithms across ten clinical metabolomics data sets for binary classification

A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations

Angiogenic imbalance and plasma lipid alterations in women with preeclampsia from a developing country.

Biomarkers of dietary energy restriction in women at increased risk of breast cancer.

Changes in the metabolic footprint of placental explant-conditioned culture medium identifies metabolic disturbances related to hypoxia and pre-eclampsia.

Characterizing the plasma metabolome during and following a maximal exercise cycling test

Closed-loop, multiobjective optimization of two-dimensional gas chromatography/mass spectrometry for serum metabolomics

Detection and identification of novel metabolomic biomarkers in preeclampsia

Development and Performance of a Gas Chromatography−Time-of-Flight Mass Spectrometry Analysis for Large-Scale Nontargeted Metabolomic Studies of Human Serum

Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum

Direct infusion mass spectrometry metabolomics dataset: a benchmark for data processing and quality control

Discrimination of modes of action of antifungal substances by use of metabolic footprinting.

Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC-MS based untargeted metabolomics practitioners

Does exercise impact gut microbiota composition in men receiving androgen deprivation therapy for prostate cancer? A single-blinded, two-armed, randomised controlled trial

Early Cord Metabolite Index and Outcome in Perinatal Asphyxia and Hypoxic-Ischaemic Encephalopathy

Evidence that multiple defects in lipid regulation occur before hyperglycemia during the prodrome of type-2 diabetes.

Explanatory Optimization of Protein Mass Spectrometry via Genetic Search

Exploring the mode of action of dithranol therapy for psoriasis: a metabolomic analysis using HaCaT cells

Functional genomics via metabolic footprinting: monitoring metabolite secretion by Escherichia coli tryptophan metabolism mutants using FT-IR and direct injection electrospray mass spectrometry

Genetic algorithms as a method for variable selection in multiple linear regression and partial least squares regression, with applications to pyrolysis mass spectrometry

Gestation-specific D-dimer reference ranges: a cross-sectional study

Global metabolic profiling of Escherichia coli cultures: an evaluation of methods for quenching and extraction of intracellular metabolites.

Growth control of the eukaryote cell: a systems biology study in yeast ⬇️

Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies.

High-throughput classification of yeast mutants for functional genomics using metabolic footprinting.

High-throughput metabolic fingerprinting of legume silage fermentations via Fourier transform infrared spectroscopy and chemometrics

Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles

Improvement in the Prediction of Neonatal Hypoxicischemic Encephalopathy with the Integration of Umbilical Cord Metabolites and Current Clinical Makers

Macronutrient Regulation of Ghrelin and Peptide YY in Pediatric Obesity and Prader-Willi Syndrome

Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

Metabolic profiling of serum using Ultra Performance Liquid Chromatography and the LTQ-Orbitrap mass spectrometry system

Metabolic profiling uncovers a phenotypic signature of small for gestational age in early pregnancy

Metabolomic profiling in multiple sclerosis: insights into biomarkers and pathogenesis

Metabolomics enables precision medicine: "A White Paper, Community Perspective"

Metabolomics reveals the physiological response of Pseudomonas putida KT2440 (UWC1) after pharmaceutical exposure

Migrating from PLS to Artificial Neural Networks - Adapting Interpretation Strategies

Migrating from partial least squares discriminant analysis to artificial neural networks: a comparison of functionally equivalent visualisation and feature contribution tools using jupyter notebooks

Molecular phenotyping of a UK population: defining the human serum metabolome

Monitoring of complex industrial bioprocesses for metabolite concentrations using modern spectroscopies and machine learning: application to gibberellic acid production

On the statistics of identifying candidate pathogen effectors

OnPLS-Based Multi-Block Data Integration: A Multivariate Approach to Interrogating Biological Interactions in Asthma

PYCHEM: a multivariate analysis package for python

Perinatal determinants of D-dimer levels in a cross-sectional study of low risk pregnant women

Preanalytical Processing and Biobanking Procedures of Biological Samples for Metabolomics Research: A White Paper, Community Perspective (for “Precision Medicine and Pharmacometabolomics Task Group”—The Metabolomics Society Initiative)

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

Proposed minimum reporting standards for data analysis in metabolomics

Rapid and quantitative detection of the microbial spoilage of meat by fourier transform infrared spectroscopy and machine learning

Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

Robust early pregnancy prediction of later preeclampsia using metabolomic biomarkers

Sildenafil Therapy Normalizes the Aberrant Metabolomic Profile in the Comt(-/-) Mouse Model of Preeclampsia/Fetal Growth Restriction

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

The application of artificial neural networks in metabolomics: a historical perspective

The effect of haemolysis on the metabolomic profile of umbilical cord blood

The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans

The metabolomic profile of umbilical cord blood in neonatal hypoxic ischaemic encephalopathy

Toward collaborative open data science in metabolomics using Jupyter Notebooks and cloud computing

Towards quality assurance and quality control in untargeted metabolomics studies

Translational biomarker discovery in clinical metabolomics: an introductory tutorial

Untargeted metabolomic analysis and pathway discovery in perinatal asphyxia and hypoxic-ischaemic encephalopathy.

Using metabolic fingerprinting of plants for evaluating nitrogen deposition impacts on the landscape level