Filtros de búsqueda

Lista de obras de Joerg Striessnig

35Ssadopine, a novel high affinity, high specific activity, L-type Ca2+ channel probe: characterization of two equipotent diastereomers with opposite allosteric properties

artículo científico publicado el 1 de febrero de 1992

A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of Cav1.4 channel activation.

artículo científico publicado en 2005

A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-gated CaV1.2 Calcium Channel Function.

artículo científico publicado en 2015

A destructive interaction mechanism accounts for dominant-negative effects of misfolded mutants of voltage-gated calcium channels.

artículo científico publicado en 2008

A mouse model to study the C-terminal regulation of CaV1.3 L-type calcium channels.

artículo científico publicado en 2012

A mutation in the beta interaction domain of the Ca(2+) channel alpha(1C) subunit reduces the affinity of the (+)-[(3)H]isradipine binding site.

artículo científico publicado en 2002

A rapid procedure for the purification of cardiac 1,4-dihydropyridine receptors from porcine heart

artículo científico publicado en 1991

Activation of L-type Ca2+ channels after purinoceptor stimulation by ATP in an alveolar epithelial cell (L2).

artículo científico publicado en 1995

Activity and calcium regulate nuclear targeting of the calcium channel beta4b subunit in nerve and muscle cells

artículo científico publicado en 2009

An oily competition: role of beta subunit palmitoylation for Ca2+ channel modulation by fatty acids.

artículo científico publicado en 2009

Analysis of membrane protein self-association in lipid systems by fluorescence particle counting: application to the dihydropyridine receptor

scientific article published on 01 April 1997

Are Ca(v)1.3 pacemaker channels in chromaffin cells? Possible bias from resting cell conditions and DHP blockers usage.

artículo científico publicado en 2011

Benzothiazepine binding domain of purified L-type calcium channels: direct labeling using a novel fluorescent diltiazem analogue.

artículo científico publicado en 1995

Biochemical characterization of a 22-kDa high affinity antiischemic drug-binding polypeptide in the endoplasmic reticulum of guinea pig liver: potential common target for antiischemic drug action.

artículo científico publicado en 1993

Biophysical classification of a CACNA1D de novo mutation as a high-risk mutation for a severe neurodevelopmental disorder

artículo científico publicado en 2020

C-terminal modulatory domain controls coupling of voltage-sensing to pore opening in Cav1.3 L-type Ca(2+) channels

artículo científico publicado en 2014

C-terminal tailoring of L-type calcium channel function

scientific article published on 01 December 2007

CACNA1D de novo mutations in autism spectrum disorders activate Cav1.3 L-type calcium channels

artículo científico publicado en 2014

Ca(V)1.3-driven SK channel activation regulates pacemaking and spike frequency adaptation in mouse chromaffin cells.

artículo científico publicado en 2012

Ca1.3 L-type calcium channels modulate depression-like behavior in mice independent of deaf phenotype

artículo científico publicado en 2009

CaV1.3 channels are essential for development and presynaptic activity of cochlear inner hair cells.

artículo científico publicado en 2003

Calcium channels from Cyprinus carpio skeletal muscle.

artículo científico publicado en 1991

Calcium channels.

artículo científico publicado en 1988

Calcium channels: the beta-subunit increases the affinity of dihydropyridine and Ca2+ binding sites of the alpha 1-subunit.

artículo científico publicado en 1994

Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1.1.

artículo científico publicado en 2022

Cav 1.3 (CACNA1D) L-type Ca(2+) channel dysfunction in CNS disorders

artículo científico publicado en 2016

Cav 1.3 L-type Ca ( 2+) channels mediate long-term adaptation in dopamine D2L-mediated GluA1 trafficking in the dorsal striatum following cocaine exposure.

artículo científico publicado en 2012

Cav1.2 L-type Ca²⁺ channels mediate cocaine-induced GluA1 trafficking in the nucleus accumbens, a long-term adaptation dependent on ventral tegmental area Ca(v)1.3 channels

artículo científico publicado en 2011

Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area

artículo científico publicado en 2014

Cav1.3 (α1D) Ca2+ Currents in Neonatal Outer Hair Cells of Mice

artículo científico publicado el 26 de septiembre de 2003

Cav1.3 calcium channels are required for normal development of the auditory brainstem

artículo científico publicado en 2011

Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons

artículo científico publicado en 2014

Cav1.3 channels produce persistent calcium sparklets, but Cav1.2 channels are responsible for sparklets in mouse arterial smooth muscle

artículo científico publicado en 2007

Cav1.4alpha1 subunits can form slowly inactivating dihydropyridine-sensitive L-type Ca2+ channels lacking Ca2+-dependent inactivation

artículo científico publicado en 2003

Chloride and potassium conductances of mouse pancreatic zymogen granules are inversely regulated by a approximately 80-kDa mdr1a gene product

artículo científico publicado en 1996

Complex molecular mechanism for dihydropyridine binding to L-type Ca(2+)-channels as revealed by fluorescence resonance energy transfer

scientific article published on 01 October 1994

Congenital stationary night blindness type 2 mutations S229P, G369D, L1068P, and W1440X alter channel gating or functional expression of Ca(v)1.4 L-type Ca2+ channels

artículo científico publicado en 2005

Conserved Ca2+-antagonist-binding properties and putative folding structure of a recombinant high-affinity dihydropyridine-binding domain.

artículo científico publicado en 2000

Coordination of Ca2+ by the pore region glutamates is essential for high-affinity dihydropyridine binding to the cardiac Ca2+ channel alpha 1 subunit.

artículo científico publicado en 1995

Current modulation and membrane targeting of the calcium channel alpha1C subunit are independent functions of the beta subunit.

artículo científico publicado en 1999

Dihydropyridine receptor of L-type Ca2+ channels: identification of binding domains for [3H](+)-PN200-110 and [3H]azidopine within the alpha 1 subunit.

artículo científico publicado en 1991

Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node

artículo científico publicado en 2012

Disturbed atrio-ventricular conduction and normal contractile function in isolated hearts from Cav1.3-knockout mice.

artículo científico publicado en 2004

Down-regulation of L-type calcium channels in inflamed circular smooth muscle cells of the canine colon.

artículo científico publicado en 2001

Familial hemiplegic migraine mutations increase Ca(2+) influx through single human CaV2.1 channels and decrease maximal CaV2.1 current density in neurons

artículo científico publicado en 2002

Functional Consequences of P/Q-type Ca2+Channel Cav2.1 Missense Mutations Associated with Episodic Ataxia Type 2 and Progressive Ataxia

artículo científico publicado el 12 de diciembre de 2001

Functional embryonic cardiomyocytes after disruption of the L-type alpha1C (Cav1.2) calcium channel gene in the mouse.

artículo científico publicado en 2000

Functional properties and modulation of extracellular epitope-tagged Ca(V)2.1 voltage-gated calcium channels.

artículo científico publicado en 2008

Gating defects of disease-causing de novo mutations in Ca1.3 Ca channels

artículo científico publicado en 2018

Germline de novo variant F747S extends the phenotypic spectrum of <i>CACNA1D</i> Ca2+ channelopathies

artículo científico publicado en 2022

Heterogeneity of L-type calcium channel alpha 1 subunits: stereoselective discrimination of different populations by the novel 1,4-dihydropyridine B 874-67

scientific article published on 01 February 1993

High affinity interaction of mibefradil with voltage-gated calcium and sodium channels.

artículo científico publicado en 2000

Human red-blood-cell Ca2+-antagonist binding sites. Evidence for an unusual receptor coupled to the nucleoside transporter

artículo científico publicado en 1985

Identification of 1,4-dihydropyridine binding regions within the alpha 1 subunit of skeletal muscle Ca2+ channels by photoaffinity labeling with diazipine

artículo científico publicado en 1991

Identification of PK-A phosphorylation sites in the carboxyl terminus of L-type calcium channel alpha 1 subunits.

artículo científico publicado en 1996

Identification of a 27-kDa high affinity phenylalkylamine-binding polypeptide as the sigma 1 binding site by photoaffinity labeling and ligand-directed antibodies

scientific article published on 01 November 1993

Identification of a new C-terminal splice variant of CaV1.3 L-type calcium channels with unique functional properties

Identification of a novel 1,4-dihydropyridine- and phenylalkylamine-binding polypeptide in calcium channel preparations

artículo científico publicado en 1987

Identification of benz(othi)azepine-binding regions within L-type calcium channel alpha1 subunits

artículo científico publicado en 1996

Identification of the benzothiazepine-binding polypeptide of skeletal muscle calcium channels with (+)-cis-azidodiltiazem and anti-ligand antibodies

artículo científico publicado en 1990

International Union of Pharmacology. XL. Compendium of voltage-gated ion channels: calcium channels.

artículo científico publicado en 2003

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels

artículo científico publicado en 2005

Iron Overload Decreases Ca V 1.3-Dependent L-Type Ca 2+ Currents Leading to Bradycardia, Altered Electrical Conduction, and Atrial Fibrillation

artículo científico publicado el 11 de julio de 2011

L-type Ca2+ channels in heart and brain

artículo científico

L-type calcium channels in insulin-secreting cells: biochemical characterization and phosphorylation in RINm5F cells.

artículo científico publicado en 1997

L-type calcium channels: binding domains for dihydropyridines and benzothiazepines are located in close proximity to each other

scientific article published on 01 March 1997

Lonely but diverse: Cav1.3 L-type Ca(2+) channels in cochlear inner hair cells

artículo científico publicado en 2013

Loss of Cav1.3 channels reveals the critical role of L-type and BK channel coupling in pacemaking mouse adrenal chromaffin cells

artículo científico publicado en 2010

Lower Affinity of Isradipine for L-Type Ca2+ Channels during Substantia Nigra Dopamine Neuron-Like Activity: Implications for Neuroprotection in Parkinson's Disease.

artículo científico publicado en 2017

Mechanism of dihydropyridine interaction with critical binding residues of L-type Ca2+ channel alpha 1 subunits.

artículo científico publicado en 2001

Modulation of Cav1.3 Ca2+ channel gating by Rab3 interacting molecule.

artículo científico publicado en 2010

Modulation of voltage- and Ca2+-dependent gating of CaV1.3 L-type calcium channels by alternative splicing of a C-terminal regulatory domain.

artículo científico publicado en 2008

Molecular Mechanism of Diltiazem Interaction with L-type Ca2+ Channels

artículo científico publicado el 16 de octubre de 1998

Molecular basis of drug interaction with L-type Ca2+ channels

artículo científico publicado en 1998

Molecular mechanism of use-dependent calcium channel block by phenylalkylamines: Role of inactivation

artículo científico publicado el 25 de noviembre de 1997

Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells

artículo científico publicado en 2007

Molecular switch from L-type Ca v 1.3 to Ca v 1.2 Ca2+ channel signaling underlies long-term psychostimulant-induced behavioral and molecular plasticity

artículo científico publicado en 2010

Neurobiology of migraine.

artículo científico publicado en 2003

Neurological phenotype and synaptic function in mice lacking the CaV1.3 alpha subunit of neuronal L-type voltage-dependent Ca2+ channels

artículo científico publicado en 2003

Opposite effects of a single IIIS5 mutation on phenylalkylamine and dihydropyridine interaction with L-type Ca2+ channels

scientific journal article

Pacemaker activity and ionic currents in mouse atrioventricular node cells.

artículo científico publicado en 2011

Pathogenicity of de novo CACNA1D Ca2+ channel variants predicted from sequence co-variation

artículo científico publicado en 2024

Pharmacodynamic interaction between mibefradil and other calcium channel blockers.

artículo científico publicado en 2000

Phenylalkylamine Ca2+ antagonist binding protein. Molecular cloning, tissue distribution, and heterologous expression

artículo científico publicado en 1995

Photoaffinity labelling of the phenylalkylamine receptor of the skeletal muscle transverse-tubule calcium channel.

artículo científico publicado en 1987

Prevalence of hypovitaminosis D and folate deficiency in healthy young female Austrian students in a health care profession.

artículo científico publicado en 2011

Purification and amino-terminal sequencing of the high affinity phenylalkylamine Ca2+ antagonist binding protein from guinea pig liver endoplasmic reticulum

scientific article published on 01 November 1994

Purification and reconstitution of calcium channel drug-receptor sites.

artículo científico publicado en 1988

Purification and reconstitution of skeletal muscle calcium channels

artículo científico publicado en 1992

Purified L-type calcium channels: only one single polypeptide (alpha 1-subunit) carries the drug receptor domains and is regulated by protein kinases

scientific article published on 01 January 1987

Purified calcium channels have three allosterically coupled drug receptors

artículo científico publicado en 1986

Purified skeletal muscle 1,4-dihydropyridine receptor forms phosphorylation-dependent oligomeric calcium channels in planar bilayers.

artículo científico publicado en 1988

Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators

artículo científico publicado en 2014

Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain.

artículo científico publicado en 2010

RIM modulates CaV1.3 Ca2+ channels.

artículo científico publicado en 2008

Receptor sites for Ca2+ channel antagonists

artículo científico publicado el 1 de junio de 1992

Regulation of CaV1.3 Ca2+ channels in cochlear inner hair cells.

artículo científico publicado en 2012

Reversible labeling of a chemosensitizer binding domain of p-glycoprotein with a novel 1,4-dihydropyridine drug transport inhibitor.

artículo científico publicado en 1996

Role of Cav1.2 L-type Ca2+ channels in vascular tone: effects of nifedipine and Mg2+

artículo científico publicado en 2007

Role of class D L-type Ca2+ channels for cochlear morphology

artículo científico publicado en 2003

Role of voltage-gated L-type Ca2+ channel isoforms for brain function.

artículo científico publicado en 2006

Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension.

artículo científico publicado en 2013

Splice variants of the CaV1.3 L-type calcium channel regulate dendritic spine morphology.

artículo científico publicado en 2016

Stabilization of negative activation voltages of Cav1.3 L-Type Ca<sup>2+</sup>-channels by alternative splicing

artículo científico publicado en 2021

Stimulation of 5-HT(2) receptors in prefrontal pyramidal neurons inhibits Ca(v)1.2 L type Ca(2+) currents via a PLCbeta/IP3/calcineurin signaling cascade.

artículo científico publicado en 2002

Structural basis of drug binding to L Ca2+ channels

artículo científico publicado en 1998

Structural determinants of CaV1.3 L-type calcium channel gating

Subcellular localization of chromogranins, calcium channels, amine carriers, and proteins of the exocytotic machinery in bovine splenic nerve

scientific article published on 01 March 1999

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Introduction and Other Protein Targets

artículo científico publicado en 2019

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels

scientific article published on 01 December 2019

Targeting voltage-gated Ca2+ channels

artículo científico publicado en 2001

The monoclonal antibody mAB 1A binds to the excitation--contraction coupling domain in the II-III loop of the skeletal muscle calcium channel alpha(1S) subunit.

artículo científico publicado en 2004

The mysteries of sigma receptors: new family members reveal a role in cholesterol synthesis

artículo científico publicado en 1997

The role of physiological afferent nerve activity during in vivo maturation of the calyx of Held synapse

scientific article published on 01 February 2007

Transfer of 1,4-dihydropyridine sensitivity from L-type to class A (BI) calcium channels

artículo científico publicado en 1996

Transfer of L-type calcium channel IVS6 segment increases phenylalkylamine sensitivity of alpha1A.

artículo científico publicado en 1996

Up-regulation of dopamine D(2)L mRNA levels in the ventral tegmental area and dorsal striatum of amphetamine-sensitized C57BL/6 mice: role of Ca(v)1.3 L-type Ca(2+) channels.

artículo científico publicado en 2006

Use-dependent block of voltage-gated Cav2.1 Ca2+ channels by petasins and eudesmol isomers.

artículo científico publicado en 2009

Very high affinity interaction of DPI 201-106 and BDF 8784 enantiomers with the phenylalkylamine-sensitive Ca2(+)-channel in Drosophila head membranes.

artículo científico publicado en 1991

Visualization of the domain structure of an L-type Ca2+ channel using electron cryo-microscopy.

artículo científico publicado en 2003

Voltage-gated calcium channels - from basic mechanisms to disease.

artículo científico publicado en 2016

[3H]HOE166 defines a novel calcium antagonist drug receptor--distinct from the 1,4 dihydropyridine binding domain

artículo científico publicado en 1989

beta subunit heterogeneity of L-type Ca(2+) channels in smooth muscle tissues

scientific article published on 01 February 2000