Lista de obras - Tao Chen - Dominio Público Uruguay

A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation

artículo científico publicado en 2014

A synthetic microbial consortium of Shewanella and Bacillus for enhanced generation of bioelectricity

artículo científico publicado en 2016

Abolishing the imbalance supply of precursors in Bacillus subtilis RH44 to increase riboflavin production

article published in 2008

Activation of glyoxylate pathway without the activation of its related gene in succinate-producing engineered Escherichia coli

artículo científico publicado en 2013

Adaptive Laboratory Evolution of <i>Halomonas bluephagenesis</i> Enhances Acetate Tolerance and Utilization to Produce Poly(3-hydroxybutyrate)

artículo científico publicado en 2022

Aerobic production of succinate from arabinose by metabolically engineered Corynebacterium glutamicum.

artículo científico publicado en 2013

An engineered non-oxidative glycolysis pathway for acetone production in Escherichia coli

artículo científico publicado en 2016

Aroma improvement by repeated freeze-thaw treatment during Tuber melanosporum fermentation

artículo científico publicado en 2015

Artificial consortium that produces riboflavin regulates distribution of acetoin and 2,3-butanediol by Paenibacillus polymyxa CJX518

artículo científico publicado en 2017

Characterization of genome-reduced Bacillus subtilis strains and their application for the production of guanosine and thymidine

artículo científico publicado en 2016

Collaborative regulation of CO2 transport and fixation during succinate production in Escherichia coli

artículo científico publicado en 2015

Combinatorial expression of different β-carotene hydroxylases and ketolases in Escherichia coli for increased astaxanthin production

scientific article published on 11 July 2019

Combinatorial optimization of CO2 transport and fixation to improve succinate production by promoter engineering

artículo científico publicado en 2016

Comparative transcriptome analysis for metabolic engineering

artículo científico publicado en 2013

Comparison of carbon-sulfur and carbon-amine bond in therapeutic drug: 4β-S-aromatic heterocyclic podophyllum derivatives display antitumor activity

artículo científico publicado en 2015

Design and synthesis of the novel DNA topoisomerase II inhibitors: esterification and amination substituted 4'-demethylepipodophyllotoxin derivates exhibiting anti-tumor activity by activating ATM/ATR signaling pathways

artículo científico publicado en 2014

Development of a markerless gene replacement system in Corynebacterium glutamicum using upp as a counter-selection marker.

artículo científico publicado en 2014

Directed evolution of adenylosuccinate synthetase from Bacillus subtilis and its application in metabolic engineering

artículo científico publicado en 2016

Directed pathway evolution of the glyoxylate shunt in Escherichia coli for improved aerobic succinate production from glycerol

artículo científico publicado en 2013

Engineering Bacillus subtilis for acetoin production from glucose and xylose mixtures

artículo científico publicado en 2013

Engineering Escherichia coli for fumaric acid production from glycerol.

artículo científico publicado en 2014

Engineering Escherichia coli for succinate production from hemicellulose via consolidated bioprocessing

artículo científico publicado en 2012

Engineering central pathways for industrial-level (3R)-acetoin biosynthesis in Corynebacterium glutamicum

scientific article published on 12 May 2020

Engineering microorganisms based on molecular evolutionary analysis: a succinate production case study

artículo científico publicado en 2014

Engineering of Serine-Deamination pathway, Entner-Doudoroff pathway and pyruvate dehydrogenase complex to improve poly(3-hydroxybutyrate) production in Escherichia coli

artículo científico publicado en 2014

Engineering of acetate recycling and citrate synthase to improve aerobic succinate production in Corynebacterium glutamicum

artículo científico publicado en 2013

Enhanced Riboflavin Production by Expressing Heterologous Riboflavin Operon from B. cereus ATCC14579 in Bacillus subtilis

Enhancement of riboflavin production by deregulating gluconeogenesis in Bacillus subtilis

artículo científico publicado en 2014

Enhancement of riboflavin production by overexpression of acetolactate synthase in a pta mutant of Bacillus subtilis

artículo científico publicado en 2007

Enhancement of riboflavin production with Bacillus subtilis by expression and site-directed mutagenesis of zwf and gnd gene from Corynebacterium glutamicum

scientific article published on 03 December 2010

Enhancing riboflavin production by genetic modification of purine pathway in Bacillus subtilis

Establishment of a markerless mutation delivery system in Bacillus subtilis stimulated by a double-strand break in the chromosome

artículo científico publicado en 2013

Evolutionary engineering of Escherichia coli for improved anaerobic growth in minimal medium accelerated lactate production

scientific article published on 08 January 2019

Expression of Vitreoscilla hemoglobin enhances growth and production of riboflavin in recombinant Bacillus subtilis

Expression of galactose permease and pyruvate carboxylase in Escherichia coli ptsG mutant increases the growth rate and succinate yield under anaerobic conditions

artículo científico publicado en 2006

Fluoride-containing podophyllum derivatives exhibit antitumor activities through enhancing mitochondrial apoptosis pathway by increasing the expression of caspase-9 in HeLa cells

artículo científico publicado en 2015

Genome shuffling: Progress and applications for phenotype improvement

artículo científico publicado en 2009

High-yield anaerobic succinate production by strategically regulating multiple metabolic pathways based on stoichiometric maximum in Escherichia coli

artículo científico publicado en 2016

Improved poly(3-hydroxybutyrate) production in Escherichia coli by inactivation of cytochrome bd-II oxidase or/and NDH-II dehydrogenase in low efficient respiratory chains

artículo científico publicado en 2014

Improved succinate production in Corynebacterium glutamicum by engineering glyoxylate pathway and succinate export system

artículo científico publicado en 2013

Improvement of the riboflavin production by engineering the precursor biosynthesis pathways in Escherichia coli

scholarly article by Zhibo Xu et al published November 2015 in Chinese Journal of Chemical Engineering

Improving Furfural Tolerance of <i>Escherichia coli</i> by Integrating Adaptive Laboratory Evolution with CRISPR-Enabled Trackable Genome Engineering (CREATE)

artículo científico publicado en 2022

Improving riboflavin production by knocking down ribF, purA and guaC genes using synthetic regulatory small RNA

artículo científico publicado en 2021

In silico metabolic engineering of Bacillus subtilis for improved production of riboflavin, Egl-237, (R,R)-2,3-butanediol and isobutanol

artículo científico publicado en 2013

Increased production of riboflavin by metabolic engineering of the purine pathway in Bacillus subtilis

article published in 2009

Increased riboflavin production by knockout of 6-phosphofructokinase I and blocking the Entner-Doudoroff pathway in Escherichia coli

artículo científico publicado en 2016

Integrating metabolomics into a systems biology framework to exploit metabolic complexity: strategies and applications in microorganisms

artículo científico publicado en 2006

Inverse metabolic engineering of Bacillus subtilis for xylose utilization based on adaptive evolution and whole-genome sequencing

artículo científico publicado en 2014

Isolation and characterization of polysaccharides with the antitumor activity from Tuber fruiting bodies and fermentation system

artículo científico publicado en 2013

Metabolic engineering of Bacillus subtilis for chiral pure meso-2,3-butanediol production

artículo científico publicado en 2016

Metabolic engineering of Bacillus subtilis for enhanced production of acetoin

artículo científico publicado en 2012

Metabolic engineering of Corynebacterium glutamicum for efficient production of 5-aminolevulinic acid

artículo científico publicado en 2015

Metabolic engineering of Escherichia coli and in silico comparing of carboxylation pathways for high succinate productivity under aerobic conditions

artículo científico publicado en 2013

Metabolic engineering of Escherichia coli for poly(3-hydroxybutyrate) production via threonine bypass

artículo científico publicado en 2015

Metabolic engineering of Escherichia coli for the production of riboflavin

artículo científico publicado en 2014

Metabolic engineering of Escherichia coli using CRISPR-Cas9 meditated genome editing.

artículo científico publicado en 2015

Metabolic engineering of thermophilic Bacillus licheniformis for chiral pure D-2,3-butanediol production

artículo científico publicado en 2012

Metabolism of L-methionine linked to the biosynthesis of volatile organic sulfur-containing compounds during the submerged fermentation of Tuber melanosporum

artículo científico publicado en 2013

Model-based reconstruction of synthetic promoter library in Corynebacterium glutamicum.

artículo científico publicado en 2018

Modular Engineering of the Flavin Pathway in Escherichia coli for Improved Flavin Mononucleotide and Flavin Adenine Dinucleotide Production

artículo científico publicado en 2019

Multiplex iterative plasmid engineering for combinatorial optimization of metabolic pathways and diversification of protein coding sequences

artículo científico publicado en 2013

NADH plays the vital role for chiral pure D-(-)-2,3-butanediol production in Bacillus subtilis under limited oxygen conditions

artículo científico publicado en 2014

Optimization of riboflavin production by recombinant Bacillus subtilis RH44 using statistical designs

artículo científico publicado en 2007

Over-expression of glucose dehydrogenase improves cell growth and riboflavin production in Bacillus subtilis

artículo científico publicado en 2006

Overexpression of glucose-6-phosphate dehydrogenase enhances riboflavin production in Bacillus subtilis

artículo científico publicado en 2009

Production of 5-aminolevulinic acid by cell free multi-enzyme catalysis

artículo científico publicado en 2016

Production of Acetoin through Simultaneous Utilization of Glucose, Xylose, and Arabinose by Engineered Bacillus subtilis

artículo científico publicado en 2016

Production of riboflavin and related cofactors by biotechnological processes

artículo científico publicado en 2020

Purification and functional characterization of thermostable 5-aminolevulinic acid synthases

artículo científico publicado en 2015

Ranking the significance of fermentation conditions on the volatile organic compounds of Tuber melanosporum fermentation system by combination of head-space solid phase microextraction and chromatographic fingerprint similarity analysis

scientific article published on 13 August 2013

Rational Engineering of Escherichia coli for High-Level Production of Riboflavin

artículo científico publicado en 2021

Recent progress in metabolic engineering of microbial formate assimilation

scientific article published on 21 June 2020

Redirection electron flow to high coupling efficiency of terminal oxidase to enhance riboflavin biosynthesis

artículo científico publicado en 2006

Screening, expression, purification and characterization of CoA-transferases for lactoyl-CoA generation

scientific article published on 08 April 2019

Significance of metal ion supplementation in the fermentation medium on the structure and anti-tumor activity of Tuber polysaccharides produced by submerged culture of Tuber melanosporum

scientific article published in 2014

Strain improvement of Sporolactobacillus inulinus ATCC 15538 for acid tolerance and production of D-lactic acid by genome shuffling

artículo científico publicado en 2009

Transcriptome analysis guided metabolic engineering of Bacillus subtilis for riboflavin production.

artículo científico publicado en 2009

Tubulin structure-based drug design for the development of novel 4β-sulfur-substituted podophyllum tubulin inhibitors with anti-tumor activity

artículo científico publicado en 2015

Lista de obras de Tao Chen

A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation

A synthetic microbial consortium of Shewanella and Bacillus for enhanced generation of bioelectricity

Abolishing the imbalance supply of precursors in Bacillus subtilis RH44 to increase riboflavin production

Activation of glyoxylate pathway without the activation of its related gene in succinate-producing engineered Escherichia coli

Adaptive Laboratory Evolution of <i>Halomonas bluephagenesis</i> Enhances Acetate Tolerance and Utilization to Produce Poly(3-hydroxybutyrate)

Aerobic production of succinate from arabinose by metabolically engineered Corynebacterium glutamicum.

An engineered non-oxidative glycolysis pathway for acetone production in Escherichia coli

Aroma improvement by repeated freeze-thaw treatment during Tuber melanosporum fermentation

Artificial consortium that produces riboflavin regulates distribution of acetoin and 2,3-butanediol by Paenibacillus polymyxa CJX518

Characterization of genome-reduced Bacillus subtilis strains and their application for the production of guanosine and thymidine

Collaborative regulation of CO2 transport and fixation during succinate production in Escherichia coli

Combinatorial expression of different β-carotene hydroxylases and ketolases in Escherichia coli for increased astaxanthin production

Combinatorial optimization of CO2 transport and fixation to improve succinate production by promoter engineering

Comparative transcriptome analysis for metabolic engineering

Comparison of carbon-sulfur and carbon-amine bond in therapeutic drug: 4β-S-aromatic heterocyclic podophyllum derivatives display antitumor activity

Design and synthesis of the novel DNA topoisomerase II inhibitors: esterification and amination substituted 4'-demethylepipodophyllotoxin derivates exhibiting anti-tumor activity by activating ATM/ATR signaling pathways

Development of a markerless gene replacement system in Corynebacterium glutamicum using upp as a counter-selection marker.

Directed evolution of adenylosuccinate synthetase from Bacillus subtilis and its application in metabolic engineering

Directed pathway evolution of the glyoxylate shunt in Escherichia coli for improved aerobic succinate production from glycerol

Engineering Bacillus subtilis for acetoin production from glucose and xylose mixtures

Engineering Escherichia coli for fumaric acid production from glycerol.

Engineering Escherichia coli for succinate production from hemicellulose via consolidated bioprocessing

Engineering central pathways for industrial-level (3R)-acetoin biosynthesis in Corynebacterium glutamicum

Engineering microorganisms based on molecular evolutionary analysis: a succinate production case study

Engineering of Serine-Deamination pathway, Entner-Doudoroff pathway and pyruvate dehydrogenase complex to improve poly(3-hydroxybutyrate) production in Escherichia coli

Engineering of acetate recycling and citrate synthase to improve aerobic succinate production in Corynebacterium glutamicum

Enhanced Riboflavin Production by Expressing Heterologous Riboflavin Operon from B. cereus ATCC14579 in Bacillus subtilis

Enhancement of riboflavin production by deregulating gluconeogenesis in Bacillus subtilis

Enhancement of riboflavin production by overexpression of acetolactate synthase in a pta mutant of Bacillus subtilis

Enhancement of riboflavin production with Bacillus subtilis by expression and site-directed mutagenesis of zwf and gnd gene from Corynebacterium glutamicum

Enhancing riboflavin production by genetic modification of purine pathway in Bacillus subtilis

Establishment of a markerless mutation delivery system in Bacillus subtilis stimulated by a double-strand break in the chromosome

Evolutionary engineering of Escherichia coli for improved anaerobic growth in minimal medium accelerated lactate production

Expression of Vitreoscilla hemoglobin enhances growth and production of riboflavin in recombinant Bacillus subtilis

Expression of galactose permease and pyruvate carboxylase in Escherichia coli ptsG mutant increases the growth rate and succinate yield under anaerobic conditions

Fluoride-containing podophyllum derivatives exhibit antitumor activities through enhancing mitochondrial apoptosis pathway by increasing the expression of caspase-9 in HeLa cells

Genome shuffling: Progress and applications for phenotype improvement

High-yield anaerobic succinate production by strategically regulating multiple metabolic pathways based on stoichiometric maximum in Escherichia coli

Improved poly(3-hydroxybutyrate) production in Escherichia coli by inactivation of cytochrome bd-II oxidase or/and NDH-II dehydrogenase in low efficient respiratory chains

Improved succinate production in Corynebacterium glutamicum by engineering glyoxylate pathway and succinate export system

Improvement of the riboflavin production by engineering the precursor biosynthesis pathways in Escherichia coli

Improving Furfural Tolerance of <i>Escherichia coli</i> by Integrating Adaptive Laboratory Evolution with CRISPR-Enabled Trackable Genome Engineering (CREATE)

Improving riboflavin production by knocking down ribF, purA and guaC genes using synthetic regulatory small RNA

In silico metabolic engineering of Bacillus subtilis for improved production of riboflavin, Egl-237, (R,R)-2,3-butanediol and isobutanol

Increased production of riboflavin by metabolic engineering of the purine pathway in Bacillus subtilis

Increased riboflavin production by knockout of 6-phosphofructokinase I and blocking the Entner-Doudoroff pathway in Escherichia coli

Integrating metabolomics into a systems biology framework to exploit metabolic complexity: strategies and applications in microorganisms

Inverse metabolic engineering of Bacillus subtilis for xylose utilization based on adaptive evolution and whole-genome sequencing

Isolation and characterization of polysaccharides with the antitumor activity from Tuber fruiting bodies and fermentation system

Metabolic engineering of Bacillus subtilis for chiral pure meso-2,3-butanediol production

Metabolic engineering of Bacillus subtilis for enhanced production of acetoin

Metabolic engineering of Corynebacterium glutamicum for efficient production of 5-aminolevulinic acid

Metabolic engineering of Escherichia coli and in silico comparing of carboxylation pathways for high succinate productivity under aerobic conditions

Metabolic engineering of Escherichia coli for poly(3-hydroxybutyrate) production via threonine bypass

Metabolic engineering of Escherichia coli for the production of riboflavin

Metabolic engineering of Escherichia coli using CRISPR-Cas9 meditated genome editing.

Metabolic engineering of thermophilic Bacillus licheniformis for chiral pure D-2,3-butanediol production

Metabolism of L-methionine linked to the biosynthesis of volatile organic sulfur-containing compounds during the submerged fermentation of Tuber melanosporum

Model-based reconstruction of synthetic promoter library in Corynebacterium glutamicum.

Modular Engineering of the Flavin Pathway in Escherichia coli for Improved Flavin Mononucleotide and Flavin Adenine Dinucleotide Production

Multiplex iterative plasmid engineering for combinatorial optimization of metabolic pathways and diversification of protein coding sequences

NADH plays the vital role for chiral pure D-(-)-2,3-butanediol production in Bacillus subtilis under limited oxygen conditions

Optimization of riboflavin production by recombinant Bacillus subtilis RH44 using statistical designs

Over-expression of glucose dehydrogenase improves cell growth and riboflavin production in Bacillus subtilis

Overexpression of glucose-6-phosphate dehydrogenase enhances riboflavin production in Bacillus subtilis

Production of 5-aminolevulinic acid by cell free multi-enzyme catalysis

Production of Acetoin through Simultaneous Utilization of Glucose, Xylose, and Arabinose by Engineered Bacillus subtilis

Production of riboflavin and related cofactors by biotechnological processes

Purification and functional characterization of thermostable 5-aminolevulinic acid synthases

Ranking the significance of fermentation conditions on the volatile organic compounds of Tuber melanosporum fermentation system by combination of head-space solid phase microextraction and chromatographic fingerprint similarity analysis

Rational Engineering of Escherichia coli for High-Level Production of Riboflavin

Recent progress in metabolic engineering of microbial formate assimilation

Redirection electron flow to high coupling efficiency of terminal oxidase to enhance riboflavin biosynthesis

Screening, expression, purification and characterization of CoA-transferases for lactoyl-CoA generation

Significance of metal ion supplementation in the fermentation medium on the structure and anti-tumor activity of Tuber polysaccharides produced by submerged culture of Tuber melanosporum

Strain improvement of Sporolactobacillus inulinus ATCC 15538 for acid tolerance and production of D-lactic acid by genome shuffling

Transcriptome analysis guided metabolic engineering of Bacillus subtilis for riboflavin production.

Tubulin structure-based drug design for the development of novel 4β-sulfur-substituted podophyllum tubulin inhibitors with anti-tumor activity