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Lista de obras de Hauke Busch

'Moving genes': how dystonia genes functionally converge on the transcriptome

scientific article published on 01 September 2020

(MIF) Drives Murine Psoriasiform Dermatitis

A Comprehensive Molecular Characterization of the Pancreatic Neuroendocrine Tumor Cell Lines BON-1 and QGP-1

scientific article published on 14 March 2020

A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes.

artículo científico publicado en 2018

A Natural mtDNA Polymorphism in Complex III Is a Modifier of Healthspan in Mice

artículo científico

A Numerical Aggregation Algorithm for the Enzyme-Catalyzed Substrate Conversion

ABA-Induced Vegetative Diaspore Formation in

artículo científico publicado en 2019

Absence of the Integrin α3 Subunit Induces an Activated Phenotype in Human Keratinocytes

artículo científico publicado en 2017

Abstract 2284: Dissecting signaling networks involved in the tumor-microenvironment crosstalk in chronic lymphocytic leukemia (CLL)

Ambrisentan, an endothelin receptor type A-selective antagonist, inhibits cancer cell migration, invasion, and metastasis

scientific article published on 28 September 2020

An integrated personal and population-based Egyptian genome reference

artículo científico publicado en 2020

B-Raf inhibitors induce epithelial differentiation in BRAF-mutant colorectal cancer cells

artículo científico publicado en 2014

BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines

artículo científico publicado en 2018

Bid Expression Network Controls Neuronal Cell Fate During Avian Ciliary Ganglion Development.

artículo científico publicado en 2018

Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-β1 expression

artículo científico publicado en 2017

Biodiversity of mycobial communities in health and onychomycosis

artículo científico publicado en 2022

Boolean Modeling Reveals the Necessity of Transcriptional Regulation for Bistability in PC12 Cell Differentiation

artículo científico publicado en 2016

Boolean approach to signalling pathway modelling in HGF-induced keratinocyte migration

artículo científico publicado en 2012

CREBBP is a target of epigenetic, but not genetic, modification in juvenile myelomonocytic leukemia.

artículo científico publicado en 2016

Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney

artículo científico publicado en 2018

Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling

artículo científico publicado en 2010

Complement Receptor 1 (CR1, CD35) Polymorphisms and Soluble CR1: A Proposed Anti-inflammatory Role to Quench the Fire of "Fogo Selvagem" Pemphigus Foliaceus

scientific article published on 22 November 2019

Consistency of the proteome in primary human keratinocytes with respect to gender, age, and skin localization

artículo científico publicado en 2013

Constitutional SAMD9L mutations cause familial myelodysplastic syndrome and transient monosomy 7.

artículo científico publicado en 2017

Constitutional absence of epithelial integrin α3 impacts the composition of the cellular microenvironment of ILNEB keratinocytes

article

Cover Image, Volume 9, Issue 4

DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation

scientific article published on 05 December 2018

Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.

artículo científico publicado en 2012

Delineating the Dynamic Transcriptome Response of mRNA and microRNA during Zebrafish Heart Regeneration

scientific article published on 28 December 2018

Dietary ursolic acid improves health span and life span in male Drosophila melanogaster

scientific article published on 29 November 2018

Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals

artículo científico publicado en 2018

Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.

artículo científico publicado en 2011

ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer

artículo científico publicado en 2016

Effect of colored noise on networks of nonlinear oscillators

artículo científico publicado en 2001

Epithelioid hemangioendotheliomas of the liver and lung in children and adolescents.

artículo científico publicado en 2017

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

artículo científico publicado en 2018

Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response.

artículo científico publicado en 2018

Gene network dynamics controlling keratinocyte migration

artículo científico publicado en 2008

Genetic Associations and Differential mRNA Expression Levels of Host Genes Suggest a Viral Trigger for Endemic Pemphigus Foliaceus

artículo científico publicado en 2022

Genetic variability of immune-related lncRNAs: polymorphisms in linc-pint and LY86-AS1 are associated with pemphigus foliaceus susceptibility

artículo científico publicado en 2021

Genetics and Omics Analysis of Autoimmune Skin Blistering Diseases

scientific article published on 15 October 2019

Genome-wide association study of psoriasis in an Egyptian population

scientific article published on 01 May 2019

Global gene expression profiling analysis reveals reduction of stemness after B-RAF inhibition in colorectal cancer cell lines

artículo científico publicado en 2015

Global remodelling of cellular microenvironment due to loss of collagen VII.

artículo científico publicado en 2013

HSPB3 protein is expressed in motoneurons and induces their survival after lesion-induced degeneration

artículo científico publicado en 2016

Host plant diet affects growth and induces altered gene expression and microbiome composition in the wood white (Leptidea sinapis) butterfly

artículo científico publicado en 2020

IL-17A is functionally relevant and a potential therapeutic target in bullous pemphigoid

artículo científico publicado en 2018

Identification and Validation of a Diagnostic and Prognostic Multi-Gene Biomarker Panel for Pancreatic Ductal Adenocarcinoma.

artículo científico publicado en 2018

Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin

artículo científico publicado en 2018

Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation

artículo científico publicado en 2010

IgG Fc sialylation is regulated during the germinal center reaction upon immunization with different adjuvants

artículo científico publicado en 2020

Image-derived models of cell organization changes during differentiation and drug treatments

artículo científico publicado en 2019

Immunoglobulin G of systemic sclerosis patients programs a pro-inflammatory and profibrotic phenotype in monocyte-like THP-1 cells

artículo científico publicado en 2020

In silico approaches and the role of ontologies in aging research

artículo científico publicado en 2013

In silico candidate variant and gene identification using inbred mouse strains

scientific article published on 11 March 2021

Inadequate mito-biogenesis in primary dermal fibroblasts from old humans is associated with impairment of PGC1A-independent stimulation.

artículo científico publicado en 2014

Induction of phenotype modifying cytokines by FERMT1 mutations.

artículo científico publicado en 2011

Infection of HeLa cells with Chlamydia trachomatis inhibits protein synthesis and causes multiple changes to host cell pathways

artículo científico publicado en 2019

Influence of spatiotemporal 1/ f α−noise on structure formation in excitable media

Influence of spatiotemporally correlated noise on structure formation in excitable media

artículo científico publicado en 2003

Information Theoretic Concepts to Unravel Cell–Cell Communication

Integration of activating and inhibitory receptor signaling by regulated phosphorylation of Vav1 in immune cells

artículo científico publicado en 2011

Integrative genomic and transcriptomic analysis in plasmablastic lymphoma identifies disruption of key regulatory pathways

artículo científico publicado en 2022

Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity

scientific article published on 19 October 2020

Label-free detection of neuronal differentiation in cell populations using high-throughput live-cell imaging of PC12 cells

artículo científico publicado en 2013

Lithocholic Acid Improves the Survival of Drosophila Melanogaster

artículo científico publicado en 2018

Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19

scientific article published on 26 November 2020

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.

artículo científico publicado en 2018

MMP14 empowers tumor-initiating breast cancer cells under hypoxic nutrient-depleted conditions

artículo científico publicado en 2018

Maternally Inherited Differences within Mitochondrial Complex I Control Murine Healthspan

artículo científico publicado en 2019

Maternally inherited differences within mitochondrial Complex I control murine healthspan

article published in 2018

Method for detecting the signature of noise-induced structures in spatiotemporal data sets

artículo científico publicado en 2002

Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks

article

Monoallelic Mutations in the Translation Initiation Codon of KLHL24 Cause Skin Fragility

scientific journal article

Network theory inspired analysis of time-resolved expression data reveals key players guiding P. patens stem cell development

artículo científico publicado en 2013

New tools for analyzing noise-induced phenomena in biological oscillators

Noise-memory induced excitability and pattern formation in oscillatory neural models

artículo científico publicado en 2006

Nurse-like cells show deregulated expression of genes involved in immunocompetence.

artículo científico publicado en 2011

Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.

artículo científico publicado en 2018

One-year surveillance of SARS-CoV-2 transmission of the ELISA cohort: A model for population-based monitoring of infection risk

artículo científico publicado en 2022

Oxidative stress as candidate therapeutic target to overcome microenvironmental protection of CLL

scientific article published on 12 July 2019

Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides

artículo científico publicado en 2018

Personalized Clinical Decision Making Through Implementation of a Molecular Tumor Board: A German Single-Center Experience

scientific article published on 16 August 2018

Polymorphisms in the Mitochondrial Genome Are Associated With Bullous Pemphigoid in Germans

scientific article published on 22 November 2019

Protein abundance of AKT and ERK pathway components governs cell type-specific regulation of proliferation

scientific article published on 24 January 2017

Proteolysis-a characteristic of tumor-initiating cells in murine metastatic breast cancer

scientific article published on 16 August 2016

Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts

artículo científico publicado en 2014

Qtlizer: comprehensive QTL annotation of GWAS results

artículo científico publicado en 2020

RARβ regulates neuronal cell death and differentiation in the avian ciliary ganglion

artículo científico publicado en 2015

RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.

artículo científico publicado en 2017

Requirements Analysis and Specification for a Molecular Tumor Board Platform Based on cBioPortal

scientific article published on 10 February 2020

Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles.

artículo científico publicado en 2018

S100A6 Regulates Endothelial Cell Cycle Progression by Attenuating Antiproliferative Signal Transducers and Activators of Transcription 1 Signaling

artículo científico publicado en 2016

SNAIL1 employs β-Catenin-LEF1 complexes to control colorectal cancer cell invasion and proliferation

artículo científico publicado en 2019

SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells.

artículo científico publicado en 2017

STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas.

artículo científico publicado en 2013

Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine

artículo científico publicado en 2015

Sequential Treatment With Targeted and Immune Checkpoint Therapy in Patients With BRAF Positive Metastatic Melanoma: The Importance of Timing?

artículo científico publicado en 2019

Smac mimetic induces an early wave of gene expression via NF-κB and AP-1 and a second wave via TNFR1 signaling

artículo científico publicado en 2018

Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study

artículo científico publicado en 2017

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

artículo científico publicado en 2018

Specific role of RhoC in tumor invasion and metastasis

artículo científico publicado en 2017

Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors

artículo científico publicado en 2015

Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency

scientific article published on 18 June 2020

Systems Biology

TGFβ-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC

artículo científico publicado en 2019

Targeting of apoptotic pathways by SMAC or BH3 mimetics distinctly sensitizes paclitaxel-resistant triple negative breast cancer cells.

artículo científico publicado en 2017

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

artículo científico publicado en 2017

The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints

artículo científico publicado en 2013

The use of urinary proteomics in the assessment of suitability of mouse models for ageing

artículo científico publicado en 2017

Understanding the mTOR signaling pathway via mathematical modeling

artículo científico publicado en 2017

mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress

artículo científico publicado en 2014

miR-149 Suppresses Breast Cancer Metastasis by Blocking Paracrine Interactions with Macrophages

artículo científico publicado en 2020

miR-181 elevates Akt signaling by co-targeting PHLPP2 and INPP4B phosphatases in luminal breast cancer.

artículo científico publicado en 2017

miR149 functions as a tumor suppressor by controlling breast epithelial cell migration and invasion

artículo científico publicado en 2014