Lista de obras - Ann-Kathrin Eisfeld - Dominio Público Uruguay

A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia

artículo científico publicado en 2013

Additional gene mutations may refine the 2017 European LeukemiaNet classification in adult patients with de novo acute myeloid leukemia aged <60 years

artículo científico publicado en 2020

Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2.

artículo científico publicado en 2016

Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies

artículo científico publicado en 2013

Clinical and functional significance of circular RNAs in cytogenetically normal AML

scientific article published on 01 January 2020

Clinical and molecular characterization of patients with acute myeloid leukemia and sole trisomies of chromosomes 4, 8, 11, 13 or 21

artículo científico publicado en 2019

Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia

artículo científico publicado en 2012

Clinical features and gene- and microRNA-expression patterns in adult acute leukemia patients with t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3)

scientific article published on 16 December 2015

Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients

artículo científico publicado en 2013

Combination of dasatinib with chemotherapy in previously untreated core binding factor acute myeloid leukemia: CALGB 10801

artículo científico publicado en 2020

Comparison of clinical and molecular characteristics of patients with acute myeloid leukemia and either TP73 or TP53 mutations

artículo científico publicado en 2020

Complex karyotype in de novo acute myeloid leukemia: typical and atypical subtypes differ molecularly and clinically

artículo científico publicado en 2019

Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia

artículo científico publicado en 2016

Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score

artículo científico publicado en 2013

Expression and prognostic impact of lncRNAs in acute myeloid leukemia

artículo científico publicado en 2014

Favorable outcome in children and adolescents with a high proportion of advanced phase disease using single/multiple autologous or matched/mismatched allogeneic stem cell transplantations.

artículo científico publicado en 2015

GAS6 expression identifies high-risk adult AML patients: potential implications for therapy

artículo científico publicado en 2013

Genetic Characterization and Prognostic Relevance of Acquired Uniparental Disomies in Cytogenetically Normal Acute Myeloid Leukemia

artículo científico publicado en 2019

Genome-wide association study identifies an acute myeloid leukemia susceptibility locus near BICRA

artículo científico publicado en 2018

Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia

artículo científico publicado en 2012

Highly Elevated Serum Hepcidin in Patients with Acute Myeloid Leukemia prior to and after Allogeneic Hematopoietic Cell Transplantation: Does This Protect from Excessive Parenchymal Iron Loading?

artículo científico publicado en 2011

Identification of Germline Mismatch Repair Gene Mutations in Lung Cancer Patients With Paired Tumor-Normal Next Generation Sequencing: A Retrospective Study

scientific article published on 26 June 2019

Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma

artículo científico publicado en 2017

Implementation of standardized variant-calling nomenclature in the age of next-generation sequencing: where do we stand?

artículo científico publicado en 2019

In rare acute myeloid leukemia patients harboring both RUNX1 and NPM1 mutations, RUNX1 mutations are unusual in structure and present in the germline

artículo científico publicado en 2013

Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway

artículo científico publicado en 2014

Kinetics of iron removal by phlebotomy in patients with iron overload after allogeneic hematopoietic cell transplantation

artículo científico publicado en 2012

Low tumor burden is associated with early B-cell reconstitution and is a predictor of favorable outcome after non-myeloablative stem cell transplant for chronic lymphocytic leukemia

artículo científico publicado en 2013

MicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies

artículo científico publicado en 2015

MonoSeq Variant Caller Reveals Novel Mononucleotide Run Indel Mutations in Tumors with Defective DNA Mismatch Repair

artículo científico publicado en 2016

Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies.

artículo científico publicado en 2018

Mutational Landscape and Gene Expression Patterns in Adult Acute Myeloid Leukemias with Monosomy 7 as a Sole Abnormality

artículo científico publicado en 2016

Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A

artículo científico publicado en 2020

Mutations associated with a 17-gene leukemia stem cell score and the score's prognostic relevance in the context of the European LeukemiaNet classification of acute myeloid leukemia

scientific article published on 14 August 2019

Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t(8;21)(q22;q22) acute myeloid leukemia

artículo científico publicado en 2016

NF1 mutations are recurrent in adult acute myeloid leukemia and confer poor outcome

NRAS isoforms differentially affect downstream pathways, cell growth, and cell transformation

scientific article published on 28 February 2014

Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia.

scientific article published on 16 July 2015

Neuroblastoma RAS viral oncogene homolog mRNA is differentially spliced to give five distinct isoforms: implications for melanoma therapy

scientific article published on 01 October 2019

No evidence for microsatellite instability in acute myeloid leukemia

artículo científico publicado en 2017

ON TRacK towards novel targets in leukemia

artículo científico publicado en 2020

Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia

artículo científico publicado en 2016

Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions ⬇️

scientific article published on 01 July 2020

Poor Survival and Differential Impact of Genetic Features of Black Patients with Acute Myeloid Leukemia

artículo científico publicado en 2020

Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias

artículo científico publicado en 2013

Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia

artículo científico publicado en 2014

Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia

artículo científico

Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8.

artículo científico publicado en 2014

Structural characterization of NRAS isoform 5

artículo científico publicado en 2016

Targeting the RAS/MAPK pathway with miR-181a in acute myeloid leukemia

artículo científico publicado en 2016

Ten-year outcome of patients with acute myeloid leukemia not treated with allogeneic transplantation in first complete remission

scholarly article published 10 July 2018

The mutational oncoprint of recurrent cytogenetic abnormalities in adult patients with de novo acute myeloid leukemia

artículo científico publicado en 2017

Thyroid Carcinomas That Occur in Familial Adenomatous Polyposis Patients Recurrently Harbor Somatic Variants in APC, BRAF, and KTM2D

artículo científico publicado en 2020

inv(16)/t(16;16) acute myeloid leukemia with non-type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations

artículo científico publicado en 2012

miR-3151 Interplays With its Host Gene BAALC and Independently Impacts on Outcome of Older Patients With Cytogenetically Normal Acute Myeloid Leukemia by Direct Deregulation of TP53

article

miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia

artículo científico publicado en 2012

Lista de obras de Ann-Kathrin Eisfeld

A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia

Additional gene mutations may refine the 2017 European LeukemiaNet classification in adult patients with de novo acute myeloid leukemia aged <60 years

Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2.

Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies

Clinical and functional significance of circular RNAs in cytogenetically normal AML

Clinical and molecular characterization of patients with acute myeloid leukemia and sole trisomies of chromosomes 4, 8, 11, 13 or 21

Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia

Clinical features and gene- and microRNA-expression patterns in adult acute leukemia patients with t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3)

Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients

Combination of dasatinib with chemotherapy in previously untreated core binding factor acute myeloid leukemia: CALGB 10801

Comparison of clinical and molecular characteristics of patients with acute myeloid leukemia and either TP73 or TP53 mutations

Complex karyotype in de novo acute myeloid leukemia: typical and atypical subtypes differ molecularly and clinically

Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia

Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score

Expression and prognostic impact of lncRNAs in acute myeloid leukemia

Favorable outcome in children and adolescents with a high proportion of advanced phase disease using single/multiple autologous or matched/mismatched allogeneic stem cell transplantations.

GAS6 expression identifies high-risk adult AML patients: potential implications for therapy

Genetic Characterization and Prognostic Relevance of Acquired Uniparental Disomies in Cytogenetically Normal Acute Myeloid Leukemia

Genome-wide association study identifies an acute myeloid leukemia susceptibility locus near BICRA

Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia

Highly Elevated Serum Hepcidin in Patients with Acute Myeloid Leukemia prior to and after Allogeneic Hematopoietic Cell Transplantation: Does This Protect from Excessive Parenchymal Iron Loading?

Identification of Germline Mismatch Repair Gene Mutations in Lung Cancer Patients With Paired Tumor-Normal Next Generation Sequencing: A Retrospective Study

Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma

Implementation of standardized variant-calling nomenclature in the age of next-generation sequencing: where do we stand?

In rare acute myeloid leukemia patients harboring both RUNX1 and NPM1 mutations, RUNX1 mutations are unusual in structure and present in the germline

Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway

Kinetics of iron removal by phlebotomy in patients with iron overload after allogeneic hematopoietic cell transplantation

Low tumor burden is associated with early B-cell reconstitution and is a predictor of favorable outcome after non-myeloablative stem cell transplant for chronic lymphocytic leukemia

MicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies

MonoSeq Variant Caller Reveals Novel Mononucleotide Run Indel Mutations in Tumors with Defective DNA Mismatch Repair

Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies.

Mutational Landscape and Gene Expression Patterns in Adult Acute Myeloid Leukemias with Monosomy 7 as a Sole Abnormality

Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A

Mutations associated with a 17-gene leukemia stem cell score and the score's prognostic relevance in the context of the European LeukemiaNet classification of acute myeloid leukemia

Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t(8;21)(q22;q22) acute myeloid leukemia

NF1 mutations are recurrent in adult acute myeloid leukemia and confer poor outcome

NRAS isoforms differentially affect downstream pathways, cell growth, and cell transformation

Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia.

Neuroblastoma RAS viral oncogene homolog mRNA is differentially spliced to give five distinct isoforms: implications for melanoma therapy

No evidence for microsatellite instability in acute myeloid leukemia

ON TRacK towards novel targets in leukemia

Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia

Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions ⬇️

Poor Survival and Differential Impact of Genetic Features of Black Patients with Acute Myeloid Leukemia

Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias

Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia

Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia

Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8.

Structural characterization of NRAS isoform 5

Targeting the RAS/MAPK pathway with miR-181a in acute myeloid leukemia

Ten-year outcome of patients with acute myeloid leukemia not treated with allogeneic transplantation in first complete remission

The mutational oncoprint of recurrent cytogenetic abnormalities in adult patients with de novo acute myeloid leukemia

Thyroid Carcinomas That Occur in Familial Adenomatous Polyposis Patients Recurrently Harbor Somatic Variants in APC, BRAF, and KTM2D

inv(16)/t(16;16) acute myeloid leukemia with non-type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations

miR-3151 Interplays With its Host Gene BAALC and Independently Impacts on Outcome of Older Patients With Cytogenetically Normal Acute Myeloid Leukemia by Direct Deregulation of TP53

miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia