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Lista de obras de Michele Saviano

13thNaples Workshop on Bioactive Peptides Conformation and activity of peptides: relationships and interactions

?-Alanine containing cyclic peptides with predetermined turned structure. V

artículo científico publicado en 1994

?-Alanine containing cyclic peptides with turned structure: The?pseudo type II ?-turn.? VI

artículo científico publicado en 1994

A Combined NMR and Computational Approach to Determine the RGDechi-hCit-αv β3 Integrin Recognition Mode in Isolated Cell Membranes

artículo científico publicado en 2015

A Late-Stage Synthetic Approach to Lanthionine-Containing Peptides via S-Alkylation on Cyclic Sulfamidates Promoted by Molecular Sieves

scientific article published on 14 November 2018

A Modified Cyclodextrin with a Fully Encapsulated Dansyl Group: Self-Inclusion in the Solid State and in Solution

A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles

scholarly article in RSC Advances, vol. 5 no. 37, 2015

A combined experimental and computational study on peptide nucleic acid (PNA) analogues of tumor suppressive miRNA-34a

scientific article published on 03 August 2019

A cyclic CCK8 analogue selective for the cholecystokinin type A receptor: design, synthesis, NMR structure and binding measurements

artículo científico publicado en 2003

A new and selective radiolabeled alphavbeta3 peptide antagonist as tracer in tumor diagnosis

artículo científico publicado en 2009

A novel approach for studying receptor-ligand interactions on living cells surface by using NUS/T1ρ-NMR methodologies combined with computational techniques: The RGDechi15D-α<sub>v</sub>β<sub>5</sub> integrin complex

artículo científico publicado en 2021

A novel class of protease targets of phosphatidylethanolamine-binding proteins (PEBP): a study of the acylpeptide hydrolase and the PEBP inhibitor from the archaeon Sulfolobus solfataricus

article

A potent cyclolinopeptide A analog: Solid state and solution conformation of cyclo[Pro-Phe-Phe-Ala-Glu(OtBu)]2

artículo científico publicado en 1995

A selective αv β5 integrin antagonist hidden into the anophelin family protein cE5 from the malaria vector Anopheles gambiae

scholarly article published 1 March 2018

A simplified model of the binding interaction between stromal cell-derived factor-1 chemokine and CXC chemokine receptor 4.

artículo científico publicado en 2003

A structural two-ring version of a tubular stack of?-rings in crystals of a cyclic D,L-hexapeptide

article

A synthetic peptide reproducing the mitochondrial targeting motif of AKAP121: a conformational study

artículo científico publicado en 2004

A-kinase anchor protein 84/121 are targeted to mitochondria and mitotic spindles by overlapping amino-terminal motifs

scientific journal article

AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress

artículo científico publicado en 2010

Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-β Oligomer Formation and Cytotoxicity

artículo científico publicado en 2016

Ac10c: a medium-ring, cycloaliphatic Calpha,alpha-disubstituted glycine. Incorporation into model peptides and preferred conformation

artículo científico publicado en 2001

Acylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation

artículo científico publicado en 2011

An Integrated Structural and Computational Study of the Thermostability of Two Thioredoxin Mutants from Alicyclobacillus acidocaldarius

artículo científico publicado en 2003

An insight into crystal chemistry and cation order of columbite-(Fe) and columbite-(Mn) from worldwide occurrences

Analogues of cyclolinopeptide A containing alpha-hydroxymethyl amino acid residues.

artículo científico publicado en 2005

Anthranilic Acid Based CCK1Receptor Antagonists and CCK-8 Have a Common Step in Their “Receptor Desmodynamic Processes”

Benzophenone photophore flexibility and proximity: molecular and crystal-state structure of a Bpa-containing trichogin dodecapeptide analogue

artículo científico publicado en 2004

Beta-alanine containing peptides: a novel molecular tool for the design of gamma-turns

scientific article published on 01 February 1992

Bicyclic peptides as models of calcium binding sites: Synthesis and conformation of a homodetic undecapeptide

scientific article published on 01 June 2000

Bicyclic peptides as type I/type II beta-turn scaffolds

scientific article published on 01 January 1996

Bicyclic peptides: solid state conformation of cyclo(Glu-Leu- Pro-Gly-Lys-Leu-Pro-Gly)cyclo(1gamma-5epsilon)Gly

artículo científico publicado en 1990

Binding studies of antimicrobial peptides to Escherichia coli cells.

artículo científico publicado en 2016

Bioactive peptides: Conformational studies of [TYR4] cyclolinopeptide A

article

Bioactive peptides: solid state, solution and molecular dynamics studies of a cyclolinopeptide A-related cystinyl cyclopentapeptide

artículo científico publicado en 1994

CCK8 peptide derivatized with diphenylphosphine for rhenium labelling: synthesis and molecular mechanics calculations

artículo científico publicado en 2002

Cationic liposomes as delivery systems for double-stranded PNA-DNA chimeras exhibiting decoy activity against NF-kappaB transcription factors

artículo científico publicado en 2002

Chemical Modification for Proteolytic Stabilization of the Selective αvβ3 Integrin RGDechi Peptide: in Vitro and in Vivo Activities on Malignant Melanoma Cells.

artículo científico publicado en 2017

Chemoselective Glycosylation of Peptides via S-Alkylation Reaction.

artículo científico publicado en 2018

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity

Conformation analysis of aspartame-based sweeteners by NMR spectroscopy, molecular dynamics simulations, and X-ray diffraction studies.

artículo científico publicado en 2006

Conformation of diastereomeric peptide sequences: structural analysis of Z-D-Val-Ac6c-Gly-L-Phe-OMe

scientific article published on 01 September 1992

Conformational behaviour of a cyclolinopeptide A analogue: two-dimensional NMR study of cyclo(Pro1-Pro-Phe-Phe-Ac6c-Ile-ala-Val8)

artículo científico publicado en 1995

Conformational features of human melanin-concentrating hormone: an NMR and computational analysis

artículo científico publicado en 2003

Conformational restriction through C alpha i C alpha i cyclization: Ac12c, the largest cycloaliphatic C alpha,alpha- disubstituted glycine known

artículo científico publicado en 2000

Conformational studies of chiral D-Lys-PNA and achiral PNA system in binding with DNA or RNA through a molecular dynamics approach

artículo científico

Conformational studies of heterochiral peptides with diastereoisomeric residues: Crystal and molecular structures of linear dipeptides derived from leucine, isoleucine, and allo-isoleucine

article

Conformational studies on synthetic peptides reproducing the dibasic processing site of pro-ocytocin-neurophysin

artículo científico publicado en 1995

Conformationally constrained CCK8 analogues obtained from a rationally designed peptide library as ligands for cholecystokinin type B receptor

artículo científico publicado en 2006

Corrigendum: Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-β Oligomer Formation and Cytotoxicity

artículo científico publicado en 2016

Crystal and molecular structure of beta-cyclodextrins functionalized with the anti-inflammatory drug Etodolac.

artículo científico publicado en 2009

Crystal structure of an S-formylglutathione hydrolase from Pseudoalteromonas haloplanktis TAC125

artículo científico publicado en 2010

Crystal structure of the W35A mutant thioredoxinh fromChlamydomonas reinhardtii: The substitution of the conserved active site Trp leads to modifications in the environment of the two catalytic cysteines

artículo científico publicado en 2000

Crystal structure of the wild-type and D30A mutant thioredoxin h of Chlamydomonas reinhardtii and implications for the catalytic mechanism

artículo científico publicado en 2001

Crystal-chemical investigation of Al 2(PO 4)(OH) 3augelite from Rapid Creek, Yukon, Canada

article

Crystal-chemical study of wavellite from Zbirov, Czech Republic

scholarly article by F. Capitelli et al published August 2014 in Mineralogical Magazine

Crystal-state conformation of C?,?-dialkylated peptides containing chiral ?-homo-residues

scholarly article by Alessandra Romanelli published in January 2001

Crystal-state conformation of Calpha,alpha-dialkylated peptides containing chiral beta-homo-residues

artículo científico publicado en 2001

Crystallization and preliminary X-ray diffraction studies of a D-lysine-based chiral PNA-DNA duplex

artículo científico publicado en 2002

Cysteine co-oxidation process driven by native peptide folding: an example on HER2 receptor model system

artículo científico publicado en 2014

Cα-Methyl, Cα-n-Propylglycine Homo-oligomers

article

Cα-Methyl,Cα-allylglycine (Mag) Homooligomers

Defect peptide chemistry: perturbations in the structure of a homopentapeptide induced by a guest residue interrupting side-chain regularity.

artículo científico publicado en 1994

Detection of oligonucleotides by PNA-peptide conjugates recognizing the biarsenical fluorescein complex FlAsH-EDT2.

artículo científico publicado en 2017

Determination of the secondary structure of peptides in the presence of Gram positive bacterium S. epidermidis cells

scholarly article in RSC Advances, vol. 6 no. 56, 2016

Development of Targeting Ligands for HER2 Receptor: Simplified Receptor Model Employed for Selecting Highly Specific Molecules

article

Discovering protein secondary structures: Classification and description of isolated α-turns

artículo científico publicado en 1996

Does tetracycline bind helix 2 of prion? An integrated spectroscopical and computational study of the interaction between the antibiotic and α helix 2 human prion protein fragments

scholarly article by Luisa Ronga published in December 2006

Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process

artículo científico publicado en 2016

Evaluation of HER2-specific peptide ligand for its employment as radiolabeled imaging probe.

artículo científico publicado en 2018

Evaluation of the anti-angiogenic properties of the new selective αVβ3 integrin antagonist RGDechiHCit

artículo científico publicado en 2011

Evidences of complex formation between DABA-based nucleo-gamma-peptides with alternate configuration backbone.

artículo científico publicado en 2009

First Archaeal PEPB-Serine Protease Inhibitor from Sulfolobus solfataricus with Noncanonical Amino Acid Sequence in the Reactive-Site Loop

artículo científico publicado en 2009

Fluorescence study for selecting specific ligands toward HER2 receptor: an example of receptor fragment approach

artículo científico publicado en 2012

Folding of peptides characterized by c3Val, a highly constrained analogue of valine

artículo científico publicado en 2003

Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles

artículo científico publicado en 2004

Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting.

artículo científico publicado en 2012

High hydrostatic pressure-induced conformational changes in protein disulfide oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus. A Fourier-transform infrared spectroscopic study

artículo científico publicado en 2010

IgE-binding properties and selectivity of peptide mimics of the FcvarepsilonRI binding site

artículo científico publicado en 2009

Imaging of alpha(v)beta(3) expression by a bifunctional chimeric RGD peptide not cross-reacting with alpha(v)beta(5).

artículo científico publicado en 2009

In silico investigation and targeting of amyloid β oligomers of different size

artículo científico publicado en 2013

Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient Delivery

Inhibition of Sp1 activity by a decoy PNA-DNA chimera prevents urokinase receptor expression and migration of breast cancer cells

artículo científico publicado en 2005

Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA-DNA duplex

artículo científico publicado en 2003

Insights into the mechanism of interaction between trehalose-conjugated beta-sheet breaker peptides and Aβ(1-42) fibrils by molecular dynamics simulations

artículo científico publicado en 2013

Insights on chiral, backbone modified peptide nucleic acids: Properties and biological activity

artículo científico

Integrin-targeting with peptide-bioconjugated semiconductor-magnetic nanocrystalline heterostructures

Interaction of the GTPase Elongation Factor Like-1 with the Shwachman-Diamond Syndrome Protein and Its Missense Mutations

artículo científico

Inversion of 310-helix screw sense in a (D-αMe)Leu homotetrapeptide induced by a guestD-(αMe)val residue

artículo científico publicado en 1995

Investigation of the Best Conditions to Obtain c(RGDfK) Peptide on Solid Phase

Maroteaux-lamy syndrome: five novel mutations and their structural localization

artículo científico publicado en 1999

Mixed conformation in C?,?-disubstituted tripeptides: X-ray crystal structures of Z-Aib-Dph-Gly-Ome and Bz-Dph-Dph-Gly-Ome

artículo científico publicado en 1994

Molecular dynamics simulation in vacuo and in solution of [Aib5,6-D-Ala8] cyclolinopeptide A: a conformational and comparative study

artículo científico publicado en 1992

Molecular dynamics simulations of PNA-PNA and PNA-DNA duplexes by the use of new parameters implemented in the GROMACS package: a conformational and dynamics study

artículo científico

Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites

artículo científico

Molecular modeling and functional characterization of the monomeric primase-polymerase domain from the Sulfolobus solfataricus plasmid pIT3.

artículo científico publicado en 2008

N-heterocyclic carbene catalysed homoenolate addition to 3-methyl-4-nitro-5-styrylisoxazoles

article

NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging.

artículo científico publicado en 2017

Nephelines from the Somma-Vesuvius volcanic complex (Southern Italy): crystal-chemical, structural and genetic investigations

article

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

artículo científico publicado en 2013

New antitumour cyclic astin analogues: synthesis, conformation and bioactivity

artículo científico publicado en 2004

New peptide nucleic acid analogues: synthesis and applications

artículo científico publicado en 2007

Nitroxyl peptides as catalysts of enantioselective oxidations

artículo científico publicado en 2002

Novel and Selective αvβ3Receptor Peptide Antagonist: Design, Synthesis, and Biological Behavior

artículo científico publicado en 2006

On-Bead Peptoid Dimerization Induced by Incorporation of Glycosylated Bridging Units in Submonomer Solid-Phase Approach to Glycopeptoids

scientific article published on 31 May 2019

PNA zipper as a dimerization tool: development of a bZip mimic.

artículo científico

Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam

artículo científico publicado en 2015

Peptide α/310-Helix Dimorphism in the Crystal State

scientific article published in 2007

Peptides binding the type E immunoglobulins

artículo científico publicado en 2009

Peptides for tumour therapy and diagnosis: current status and future directions.

scientific article published on January 2009

Probing the peptidylglycine alpha-hydroxylating monooxygenase active site with novel 4-phenyl-3-butenoic acid based inhibitors

artículo científico publicado en 2010

Pt(II) complexes of amino acids and peptides II. Structural analysis of trans-[Cl2-Pt-(H-Aib-OH)2n] and trans-[Pt-(H-Aib-O−)2]

Pt(II) complexes of amino acids and peptides III. X-ray diffraction study of [Cl(Ph3P)Pt(H-Aib-O)]

RGDechi-hCit: αvβ3 selective pro-apoptotic peptide as potential carrier for drug delivery into melanoma metastatic cells

artículo científico publicado en 2014

SPR and NMR characterization of the molecular interaction between A9 peptide and a model system of HER2 receptor: A fragment approach for selecting peptide structures specific for their target

artículo científico publicado en 2019

Selective Targeting of αvβ5 Integrin in HepG2 Cell Line by RGDechi15D Peptide

scientific article published on 19 September 2020

Selectively functionalized cyclodextrins and their metal complexes

artículo científico publicado en 2009

Self-assembling of Fmoc-GC Peptide Nucleic Acid dimers into highly fluorescent aggregates

artículo científico publicado en 2018

Solid phase synthesis of DNA-3′-PNA chimeras by using Bhoc/Fmoc PNA monomers

Solid phase synthesis of TyrT, a thymine-tyrosine conjugate with poly(A) RNA-binding ability

artículo científico publicado en 2016

Solid state and solution conformation of [Ala7]-phalloidin: a synthetic phallotoxin analogue

artículo científico publicado en 2001

Solution structure and backbone dynamics of the K18G/R82E Alicyclobacillus acidocaldarius thioredoxin mutant: a molecular analysis of its reduced thermal stability

artículo científico publicado en 2004

Solvent-mediated conformational transition in β-alanine containing cyclic peptides. VIII

artículo científico publicado en 1996

Specific interaction between cyclophilin and cyclic peptides

artículo científico publicado el 1 de septiembre de 1995

Stereochemical behavior of acyclic peptide-cation complexes

scientific article published in 1990

Straightforward entry to S-glycosylated fmoc-amino acids and their application to solid phase synthesis of glycopeptides and glycopeptidomimetics.

artículo científico publicado en 2015

Structural and kinetic characterization of native laccases from Pleurotus ostreatus, Rigidoporus lignosus, and Trametes trogii

artículo científico publicado en 2001

Structural identification of an HER2 receptor model binding pocket to optimize lead compounds: a combined experimental and computational approach

artículo científico publicado en 2016

Structure and Dynamics of Elastin Building Blocks. Boc-LG-OEt, Boc-VG-OEt, Boc-VGG-OH

artículo científico publicado el 1 de abril de 1998

Sulfolobus solfataricus protein disulphide oxidoreductase: insight into the roles of its redox sites

artículo científico publicado en 2008

Synthesis and Characterization of a Selective Alpha(v)Beta(3) Receptor Cyclic Peptide Antagonist Functionalized with a Chelating Group for Metal Labelling

Synthesis and biological evaluation of cyclic and branched peptide analogues as ligands for cholecystokinin type 1 receptor

artículo científico publicado en 2007

Synthesis and solution characterization of a porphyrin-CCK8 conjugate.

artículo científico publicado en 2001

Synthesis and structural characterization of 6I,6II-diamino-6I,6II-dideoxy-cyclomaltoheptaose, a difunctionalized β-cyclodextrin

article

Synthesis and supramolecular features of hybrid POM/onium solid-state assemblies

Synthesis of Novel Indole-Based Ring Systems by Acid-Catalysed Condensation from α-Amino Aldehydes andL-Trp-OMe

Synthesis of a l-lysine-based alternate alpha,epsilon-peptide: a novel linear polycation with nucleic acids-binding ability

artículo científico publicado en 2010

Synthesis, conformational analysis and immunological activity of beta3Phe-substituted Cyclolinopeptide A analogues.

artículo científico publicado en 2009

Synthetic peptides mimicking the interleukin-6/gp 130 interaction: a two-helix bundle system. Design and conformational studies

scientific article published on 01 February 2003

Temperature-, SDS-, and pH-induced conformational changes in protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus: a dynamic simulation and fourier transform infrared spectroscopic study

artículo científico publicado en 2005

Tetrazole analogues of cyclolinopeptide A: synthesis, conformation, and biology.

artículo científico publicado en 2002

The influence of liposomal formulation on the incorporation and retention of PNA oligomers

The polypeptide 310-helix as a template for molecular recognition studies. Structural characterization of a sidechain functionalized octapeptide

artículo científico publicado en 1995

The psychrophilic bacterium Pseudoalteromonas halosplanktis TAC125 possesses a gene coding for a cold-adapted feruloyl esterase activity that shares homology with esterase enzymes from γ-proteobacteria and yeast

article

The renaissance era of peptides in drug discovery at the 14th Naples workshop on bioactive peptides

article by Giancarlo Morelli et al published 10 April 2015 in Journal of Peptide Science

The role of segment 32-47 of cholecystokinin receptor type A in CCK8 binding: synthesis, nuclear magnetic resonance, circular dichroism and fluorescence studies

scholarly article by Stefania De Luca published in January 2003

Therapeutic Potential of a Novel αβ₃ Antagonist to Hamper the Aggressiveness of Mesenchymal Triple Negative Breast Cancer Sub-Type

scientific article published on 24 January 2019

Time-resolved fluorescence spectroscopy and molecular dynamics simulations point out the effects of pressure on the stability and dynamics of the porcine odorant-binding protein

artículo científico publicado en 2008

Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites

artículo científico publicado en 2002

Tryptophan phosphorescence studies of the D-galactose/D-glucose-binding protein from Escherichia coli provide a molecular portrait with structural and dynamics features of the protein

artículo científico publicado en 2007

X-ray Diffraction Analysis and Conformational Energy Computations of β-Turn and 310-Helical Peptides Based on α-Amino Acids with an Olefinic Side Chain. Implications for Ring-Closing Metathesis

article

[99mTc][Tc(N)PNP43]-labeled RGD peptides as new probes for a selective detection of αvβ3 Integrin: synthesis, structure-activity and pharmacokinetic studies

scientific article published on 17 October 2018

beta-Alanine containing peptides: gamma-turns in cyclotetrapeptides

scientific article published on 01 April 1993

gamma-Hydroxymethyl PNAs: Synthesis, interaction with DNA and inhibition of protein/DNA interactions

artículo científico publicado en 2010

γ Sulphate PNA (PNA S): highly selective DNA binding molecule showing promising antigene activity

artículo científico publicado en 2012