Lista de obras - Patrick Deelen - Dominio Público Uruguay

A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.

artículo científico publicado en 2016

A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency

artículo científico publicado en 2016

A high-quality human reference panel reveals the complexity and distribution of genomic structural variants

scientific article published on 06 October 2016

A proteomics and transcriptomics approach to identify leukemic stem cell (LSC) markers

artículo científico publicado en 2012

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

artículo científico publicado en 2022

Author Correction: Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome

scholarly article published in Nature Genetics

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

artículo científico publicado en 2017

Calling genotypes from public RNA-sequencing data enables identification of genetic variants that affect gene-expression levels

artículo científico publicado en 2015

Cohort profile: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics

artículo científico publicado en 2015

Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

artículo científico

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

artículo científico

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

artículo científico publicado en 2016

Disease variants alter transcription factor levels and methylation of their binding sites

artículo científico publicado en 2016

Exome sequencing in a family segregating for celiac disease

artículo científico publicado en 2011

Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant

artículo científico publicado en 2013

Functional and Genomic Architecture of Borrelia burgdorferi-Induced Cytokine Responses in Humans.

artículo científico publicado en 2016

Genetic and epigenetic regulation of gene expression in fetal and adult human livers

artículo científico publicado en 2014

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

artículo científico publicado en 2015

Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration

artículo científico publicado en 2014

Identification of context-dependent expression quantitative trait loci in whole blood

artículo científico publicado en 2016

Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'.

artículo científico publicado en 2014

Improving the diagnostic yield of exome- sequencing by predicting gene-phenotype associations using large-scale gene expression analysis

artículo científico publicado en 2019

Improving the diagnostic yield of exome-sequencing, by predicting gene-phenotype associations using large-scale gene expression analysis

article

Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome

Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi

artículo científico publicado en 2016

Lessons learned from whole exome sequencing in multiplex families affected by a complex genetic disorder, intracranial aneurysm

artículo científico publicado en 2015

Multi-omics strategies for detecting gene-environment interactions ⬇️

PhD thesis of Patrick Deelen

Multi-omics strategies for detecting gene-environment interactions ⬇️

Electronic edition of PhD thesis of Patrick Deelen

Pooled Resequencing of 122 Ulcerative Colitis Genes in a Large Dutch Cohort Suggests Population-Specific Associations of Rare Variants in MUC2

artículo científico publicado en 2016

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

artículo científico publicado en 2016

Population-specific genotype imputations using minimac or IMPUTE2.

artículo científico publicado en 2015

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

artículo científico publicado en 2016

Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs.

artículo científico publicado en 2018

TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation

artículo científico publicado en 2016

The Genome of the Netherlands: design, and project goals

artículo científico publicado en 2014

The effect of host genetics on the gut microbiome

artículo científico

Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

artículo científico publicado en 2011

Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression

artículo científico publicado en 2012

Lista de obras de Patrick Deelen

A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.

A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency

A high-quality human reference panel reveals the complexity and distribution of genomic structural variants

A proteomics and transcriptomics approach to identify leukemic stem cell (LSC) markers

Associations of autozygosity with a broad range of human phenotypes

Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Author Correction: Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

Calling genotypes from public RNA-sequencing data enables identification of genetic variants that affect gene-expression levels

Cohort profile: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics

Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

Disease variants alter transcription factor levels and methylation of their binding sites

Exome sequencing in a family segregating for celiac disease

Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant

Functional and Genomic Architecture of Borrelia burgdorferi-Induced Cytokine Responses in Humans.

Genetic and epigenetic regulation of gene expression in fetal and adult human livers

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration

Identification of context-dependent expression quantitative trait loci in whole blood

Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'.

Improving the diagnostic yield of exome- sequencing by predicting gene-phenotype associations using large-scale gene expression analysis

Improving the diagnostic yield of exome-sequencing, by predicting gene-phenotype associations using large-scale gene expression analysis

Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome

Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi

Lessons learned from whole exome sequencing in multiplex families affected by a complex genetic disorder, intracranial aneurysm

Multi-omics strategies for detecting gene-environment interactions ⬇️

Multi-omics strategies for detecting gene-environment interactions ⬇️

Pooled Resequencing of 122 Ulcerative Colitis Genes in a Large Dutch Cohort Suggests Population-Specific Associations of Rare Variants in MUC2

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

Population-specific genotype imputations using minimac or IMPUTE2.

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs.

TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation

The Genome of the Netherlands: design, and project goals

The effect of host genetics on the gut microbiome

Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression