52 Genetic Loci Influencing Myocardial Mass
artículo científico publicado en 2016
A Combined Linkage and Exome Sequencing Analysis for Electrocardiogram Parameters in the Erasmus Rucphen Family Study
artículo científico publicado en 2016
A Genome-Wide Association Study in isolated populations reveals new genes associated to common food likings.
artículo científico publicado en 2016
A Genome-Wide Linkage Study for Chronic Obstructive Pulmonary Disease in a Dutch Genetic Isolate Identifies Novel Rare Candidate Variants.
artículo científico publicado en 2018
A Genome-Wide Scan for MicroRNA-Related Genetic Variants Associated With Primary Open-Angle Glaucoma
artículo científico publicado en 2017
A Genome-Wide Search for Genes Involved in Type 2 Diabetes in a Recently Genetically Isolated Population From the Netherlands
article
A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila
artículo científico publicado en 2011
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
artículo científico publicado en 2018
A Large-Scale Population-Based Analysis of Common Genetic Variation in the Thyroid Hormone Receptor Alpha Locus and Bone
scholarly article by Marco Medici et al published February 2012 in Thyroid
A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose and Type 2 Diabetes
artículo científico publicado en 2017
A Method for Pooling Alleles from Different Genotyping Experiments
A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms
article
A case-control study of apolipoprotein E genotypes in Alzheimer's disease associated with Down's syndrome. Dutch Study Group on Down's Syndrome and Ageing
artículo científico publicado en 1995
A case-control study on the effect of p53 and p73 gene polymorphisms on gastric cancer risk and progression
artículo científico publicado en 2009
A catalog of genetic loci associated with kidney function from analyses of a million individuals
scientific article published on 31 May 2019
A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy
artículo científico publicado en 2018
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.
artículo científico publicado en 2017
A common polymorphism in the complement factor H gene is associated with increased risk of myocardial infarction: the Rotterdam Study
artículo científico publicado en 2006
A critical appraisal of epidemiological studies comes from basic knowledge: a reader's guide to assess potential for biases
artículo científico publicado en 2007
A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions
artículo científico publicado en 2008
A cross-omics integrative study of metabolic signatures of chronic obstructive pulmonary disease
scientific article published on 16 July 2020
A deletion in DJ-1 and the risk of dementia--a population-based survey
artículo científico publicado en 2004
A genetic association study of the IGF-1 gene and radiological osteoarthritis in a population-based cohort study (the Rotterdam Study).
artículo científico publicado en 1998
A genetic epidemiologic study of candidate genes involved in the optic nerve head morphology
artículo científico publicado en 2012
A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk
artículo científico publicado en 2014
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
artículo científico publicado en 2012
A genome-wide association meta-analysis identifies new childhood obesity loci
artículo científico publicado en 2012
A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly
artículo científico publicado en 2014
A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project
artículo científico publicado en 2009
A genome-wide association search for type 2 diabetes genes in African Americans
artículo científico publicado en 2012
A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25.
artículo científico publicado en 2010
A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.
artículo científico publicado en 2010
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes
scientific article published on 02 August 2019
A genome-wide association study of aging
artículo científico publicado en 2011
A genome-wide association study of depressive symptoms
scientific journal article
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation
artículo científico publicado en 2009
A genome-wide association study of optic disc parameters
artículo científico publicado en 2010
A genome-wide association study of sleep habits and insomnia
artículo científico publicado en 2013
A genome-wide association study reveals variants in ARL15 that influence adiponectin levels
artículo científico publicado en 2009
A genome-wide linkage study of individuals with high scores on NEO personality traits
artículo científico publicado en 2011
A genome-wide screen for depression in two independent Dutch populations
artículo científico publicado en 2010
A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol
artículo científico publicado en 2011
A genome-wide search for linkage-disequilibrium with type 1 diabetes in a recent genetically isolated population from the Netherlands
artículo científico publicado en 2002
A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population
artículo científico publicado en 2007
A genomic background based method for association analysis in related individuals
artículo científico publicado en 2007
A high-quality human reference panel reveals the complexity and distribution of genomic structural variants
scientific article published on 06 October 2016
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
artículo científico publicado en 2015
A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium
artículo científico publicado en 2010
A meta-analysis of genome-wide association studies identifies multiple longevity genes
scientific article published on 14 August 2019
A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level
artículo científico publicado en 2010
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals
scientific article published on 20 August 2019
A metabolomic profile is associated with the risk of incident coronary heart disease
artículo científico publicado en 2014
A methodological perspective on genetic risk prediction studies in type 2 diabetes: recommendations for future research
artículo científico publicado en 2011
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
scientific article published on 10 April 2019
A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis
artículo científico publicado en 2001
A novel Alzheimer disease locus located near the gene encoding tau protein.
artículo científico publicado en 2015
A novel common variant in DCST2 is associated with length in early life and height in adulthood
artículo científico publicado en 2014
A novel method for serum lipoprotein profiling using high performance capillary isotachophoresis
artículo científico publicado en 2016
A novel presenilin 1 mutation (L174 M) in a large Cuban family with early onset Alzheimer disease
artículo científico publicado en 2002
A polymorphic CA repeat in the IGF-I gene is associated with gender-specific differences in body height, but has no effect on the secular trend in body height
artículo científico publicado en 2004
A polymorphic CA repeat in the promoter region of the insulin-like growth factor-I (IGF-I) gene
artículo científico publicado en 2003
A polymorphism in the IGF-I gene influences the age-related decline in circulating total IGF-I levels
scientific article published on 01 February 2003
A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction
artículo científico publicado en 2001
A polymorphism in the regulatory region of PRNP is associated with increased risk of sporadic Creutzfeldt-Jakob disease
artículo científico publicado en 2011
A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy
article
A population-based study of familial Alzheimer disease: linkage to chromosomes 14, 19, and 21.
artículo científico publicado en 1994
A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
artículo científico publicado en 2016
A priori collaboration in population imaging: The Uniform Neuro-Imaging of Virchow-Robin Spaces Enlargement consortium
artículo científico publicado en 2015
A promoter polymorphism of the insulin-like growth factor-I gene is associated with left ventricular hypertrophy
artículo científico publicado en 2005
A rare missense variant in RCL1 segregates with depression in extended families
artículo científico publicado en 2017
A reference panel of 64,976 haplotypes for genotype imputation
artículo científico publicado en 2016
A study of familial aggregation of depression, dementia and Parkinson's disease
artículo científico publicado en 1998
A study of gene--environment interaction on the gene for angiotensin converting enzyme: a combined functional and population based approach
artículo científico publicado en 2004
A study of the SORL1 gene in Alzheimer's disease and cognitive function
artículo científico publicado en 2009
A systematic evaluation of 151 candidate genes for their association with osteoporosis and osteoporotic fracture in a meta-analysis of genome-wide association data
article
A systematic review of meta-analyses on gene polymorphisms and gastric cancer risk
scientific article published on September 2008
A unified approach to modelling linkage to quantitative and qualitative traits
artículo científico publicado en 2003
A variant of the IGF-I gene is associated with blood pressure but not with left heart dimensions at the age of 2 years: the Generation R Study
scientific article published on 10 June 2008
ACE gene is associated with Alzheimer's disease and atrophy of hippocampus and amygdala
artículo científico publicado en 2004
ACE polymorphisms
artículo científico publicado en 2006
APOE and the risk of PD with or without dementia in a population-based study
article
APOE genotyping in differential diagnosis of Alzheimer's disease
artículo científico publicado en 1996
APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy
artículo científico publicado en 2006
ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure
artículo científico publicado en 2015
ATP5H/KCTD2 locus is associated with Alzheimer's disease risk.
artículo científico publicado en 2013
Accuracy of self-reported family history is strongly influenced by the accuracy of self-reported personal health status of relatives
artículo científico publicado en 2011
Adherence to and dosing of beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitors in the general population differs according to apolipoprotein E-genotypes
artículo científico publicado en 2003
Adherence to and dosing of statins differs according to apolipoprotein E-genotypes.
artículo científico publicado en 2002
Adiposity as a cause of cardiovascular disease: a Mendelian randomization study
artículo científico publicado en 2015
Adjacent genes, for COL2A1 and the vitamin D receptor, are associated with separate features of radiographic osteoarthritis of the knee
artículo científico publicado en 2000
Age at onset of genetic (E200K) and sporadic Creutzfeldt-Jakob diseases is modulated by the gene
article
Age- and sex-specific causal effects of adiposity on cardiovascular risk factors
artículo científico publicado en 2015
Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms
artículo científico publicado en 2016
Agreement between oral contraceptive users and prescribers: Implications for case-control studies
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artículo científico publicado el 1 de mayo de 1992
Alcohol and mortality. Results from the EPOZ (Epidemiologic Study of Cardiovascular Risk Indicators) follow-up study
artículo científico publicado en 1994
Alcohol and tobacco consumption as risk factors for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group
artículo científico publicado en 1991
Alcohol consumption and risk of dementia: the Rotterdam Study
artículo científico publicado en 2002
Alcohol intake in relation to brain magnetic resonance imaging findings in older persons without dementia
artículo científico publicado en 2004
Aldehyde dehydrogenase 2 and head and neck cancer: a meta-analysis implementing a Mendelian randomization approach
artículo científico publicado en 2009
Allelic variants of cytochrome P450 2C9 modify the interaction between nonsteroidal anti-inflammatory drugs and coumarin anticoagulants
artículo científico publicado en 2005
Alpha-adducin polymorphism, atherosclerosis, and cardiovascular and cerebrovascular risk
artículo científico publicado en 2006
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome
Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers
artículo científico publicado en 2018
Alzheimer's disease and glaucoma-reply
scholarly article by Sarah F Janssen et al published March 2014 in Progress in Retinal and Eye Research
Alzheimer's disease genes and cognition in the nondemented general population
artículo científico publicado en 2012
Alzheimer's disease in Down syndrome: An overlooked population for prevention trials
scholarly article by Andre Strydom et al published 2018 in Alzheimer's & dementia (New York, N. Y.)
Amyloid precursor protein gene mutation in early-onset Alzheimer's disease
artículo científico publicado en 1991
Amyloid β secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease
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artículo científico publicado el 2 de noviembre de 2001
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype
artículo científico publicado en 2016
An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group
artículo científico publicado en 2016
An R package "VariABEL" for genome-wide searching of potentially interacting loci by testing genotypic variance heterogeneity
artículo científico publicado en 2012
An approach for cutting large and complex pedigrees for linkage analysis
artículo científico publicado en 2008
An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses
artículo científico publicado en 2009
An epidemiological perspective on the future of direct-to-consumer personal genome testing
artículo científico publicado en 2010
An igf-I gene polymorphism modifies the risk of diabetic retinopathy
artículo científico publicado en 2006
An insulin-like growth factor-I gene polymorphism modifies the risk of microalbuminuria in subjects with an abnormal glucose tolerance
artículo científico publicado en 2006
An insulin-like growth factor-I promoter polymorphism is associated with increased mortality in subjects with myocardial infarction in an elderly Caucasian population
artículo científico publicado en 2006
An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.
artículo científico publicado en 2019
Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype
scientific article published on 10 June 2019
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
artículo científico publicado en 2013
Angiotensin converting enzyme gene polymorphism and cardiovascular morbidity and mortality: the Rotterdam Study
artículo científico publicado en 2005
Angiotensin converting enzyme gene, smoking and mortality in a population-based study
article
Angiotensin converting enzyme insertion/deletion polymorphism and the risk of heart failure in hypertensive subjects.
artículo científico publicado en 2004
Angiotensin-converting enzyme gene insertion/deletion polymorphism and breast cancer risk
artículo científico publicado en 2005
Angiotensin-converting enzyme gene polymorphism and carotid artery wall thickness: a meta-analysis
artículo científico publicado en 2003
Angiotensin-converting enzyme gene polymorphism and common carotid stiffness. The Rotterdam study
artículo científico publicado en 2004
Angiotensinogen M235T polymorphism and symptoms of depression in a population-based study and a family-based study
artículo científico publicado en 2008
Angiotensinogen M235T polymorphism and the risk of myocardial infarction and stroke among hypertensive patients on ACE-inhibitors or β-blockers
Angiotensinogen promoter B-haplotype associated with cerebral small vessel disease enhances basal transcriptional activity
artículo científico publicado en 2004
Antiepileptic drug regimens and major congenital abnormalities in the offspring
scientific article published on 01 November 1999
Antipsychotic-induced movement disorders in long-stay psychiatric patients and 45 tag SNPs in 7 candidate genes: a prospective study
artículo científico publicado en 2012
ApoE gene polymorphisms, BMD, and fracture risk in elderly men and women: the Rotterdam study
artículo científico publicado en 2004
Apolipoprotein E and carotid artery atherosclerosis: the Rotterdam study
artículo científico publicado en 2001
Apolipoprotein E epsilon4 allele is associated with left ventricular systolic dysfunction
artículo científico publicado en 2004
Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation
artículo científico publicado en 1997
Apolipoprotein E gene and sporadic frontal lobe dementia.
artículo científico publicado en 1997
Apolipoprotein E gene is related to mortality only in normal weight individuals: the Rotterdam Study
artículo científico publicado en 2007
Apolipoprotein E genotype and association between smoking and early onset Alzheimer's disease
artículo científico publicado en 1995
Apolipoprotein E genotype and concomitant clinical features in early-onset Alzheimer's disease
artículo científico publicado en 1996
Apolipoprotein E genotype and progression of Alzheimer's disease: the Rotterdam Study
artículo científico publicado en 1999
Apolipoprotein E genotype does not affect the age of onset of dementia in families with defined tau mutations
article
Apolipoprotein E genotype in patients with alzheimer's disease: Implications for the risk of dementia among relatives
article
Apolipoprotein E genotype, atherosclerosis, and cognitive decline: the Rotterdam Study
artículo científico publicado en 1998
Apolipoprotein E4 allele in a population–based study of early–onset Alzheimer's disease
scientific article published on 01 May 1994
Apolipoprotein E4 in the temporal variant of frontotemporal dementia
artículo científico publicado en 2002
Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes
artículo científico publicado en 2013
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
artículo científico publicado en 2010
Association analysis of bitter receptor genes in five isolated populations identifies a significant correlation between TAS2R43 variants and coffee liking
artículo científico publicado en 2014
Association analysis of ten candidate genes in a large multinational cohort of small for gestational age children and children with idiopathic short stature (NESTEGG study).
artículo científico publicado en 2013
Association between an insulin-like growth factor I gene promoter polymorphism and bone mineral density in the elderly: the Rotterdam Study
artículo científico publicado en 2003
Association between apolipoprotein-epsilon4 and long-term outcome after traumatic brain injury
artículo científico publicado en 2007
Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies
artículo científico publicado en 2011
Association between genetic variation in the gene for insulin-like growth factor-I and low birthweight
artículo científico publicado en 2002
Association between type 2 diabetes loci and measures of fatness
artículo científico publicado en 2010
Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk
artículo científico publicado en 2003
Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers
scientific article published on 03 July 2019
Association of Alzheimer's disease GWAS loci with MRI markers of brain aging
artículo científico publicado en 2015
Association of Genetic Variants with Primary Open-Angle Glaucoma among Individuals with African Ancestry
artículo científico publicado en 2019
Association of HSP70 and its co-chaperones with Alzheimer's disease
artículo científico publicado en 2011
Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants
artículo científico publicado en 2014
Association of adiposity genetic variants with menarche timing in 92,105 women of European descent
artículo científico publicado en 2013
Association of an APOC3 promoter variant with type 2 diabetes risk and need for insulin treatment in lean persons
artículo científico publicado en 2011
Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts
artículo científico publicado en 2018
Association of circulating metabolites in plasma or serum and risk of stroke: Meta-analysis from seven prospective cohorts
scientific article published on 02 December 2020
Association of cognitive functioning with retinal nerve fiber layer thickness.
artículo científico publicado en 2009
Association of common genetic variants with brain microbleeds: A Genome-wide Association Study
scientific article published on 10 September 2020
Association of cyclin-dependent kinase 5 and neuronal activators p35 and p39 complex in early-onset Alzheimer's disease
artículo científico publicado en 2005
Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium
scientific journal article
Association of heat shock proteins with Parkinson's disease
artículo científico publicado en 2011
Association of heat shock proteins with all-cause mortality
artículo científico publicado en 2012
Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals
artículo científico publicado en 2011
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks
artículo científico publicado en 2014
Association of lysophosphatidic acids with cerebrospinal fluid biomarkers and progression to Alzheimer's disease
artículo científico publicado en 2020
Association of matrilin-3 polymorphisms with spinal disc degeneration and osteoarthritis of the first carpometacarpal joint of the hand
artículo científico publicado en 2006
Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts
scholarly article by Galit Weinstein et al published 2019 in PLOS ONE
Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts
scientific article published on April 2009
Association of the IGF1 gene with fasting insulin levels
artículo científico publicado en 2016
Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip.
artículo científico publicado en 2004
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study
artículo científico publicado en 2008
Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects
Associations between the deletion polymorphism of the angiotensin 1-converting enzyme gene and ocular signs of primary open-angle glaucoma
artículo científico publicado en 2004
Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium
artículo científico publicado en 2014
Associations of autozygosity with a broad range of human phenotypes
scientific article published on 31 October 2019
Associations with intraocular pressure across Europe: The European Eye Epidemiology (E3) Consortium
artículo científico publicado en 2016
Attention-deficit/hyperactivity disorder (ADHD): parents' judgment about school, teachers' judgment about home
artículo científico publicado en 2004
Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases
artículo científico
Author Correction: Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps
artículo científico publicado en 2018
Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
scientific article published on 01 September 2019
Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies
artículo científico publicado en 2020
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
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scientific article published on 01 May 2019
Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles
artículo científico publicado en 2013
Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation
scientific article published in Nature Communications
Autosomal recessive early onset parkinsonism is linked to three loci: PARK2, PARK6, and PARK7
artículo científico publicado en 2002
BSE and variant Creutzfeldt-Jakob disease: never say never
artículo científico publicado en 2002
Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium
artículo científico publicado en 2013
Beyond public health genomics: proposals from an international working group
artículo científico publicado en 2014
Biological, clinical and population relevance of 95 loci for blood lipids
artículo científico publicado en 2010
Bivariate Genome-Wide Association Study of Depressive Symptoms with Type 2 Diabetes and Quantitative Glycemic Traits
artículo científico publicado en 2017
Blood lipids influence DNA methylation in circulating cells
artículo científico publicado en 2016
Blood metabolomic measures associate with present and future glycemic control in type 2 diabetes
Blood-based metabolic signatures in Alzheimer's disease
artículo científico publicado en 2017
Bone Mineral Density in Sjögren Syndrome Patients with and Without Distal Renal Tubular Acidosis
artículo científico publicado en 2016
Breast-feeding modifies the association of PPARgamma2 polymorphism Pro12Ala with growth in early life: the Generation R Study
artículo científico publicado en 2009
Burden of genetic risk variants in multiple sclerosis families in the Netherlands
artículo científico publicado en 2016
CDH6 and HAGH protein levels in plasma associate with Alzheimer's disease in APOE ε4 carriers
scientific article published on 19 May 2020
CHOLESTERYL ESTER TRANSFER PROTEIN GENE AND CORONARY HEART DISEASE MORTALITY: THE ROTTERDAM STUDY
article
COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression
artículo científico publicado en 2018
CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and neck cancer
scientific article published on 05 July 2007
CYP1A2 and coffee intake and the modifying effect of sex, age, and smoking
artículo científico publicado en 2012
CYP2D6 polymorphism in Parkinson's disease: The Rotterdam study
artículo científico publicado en 2001
CYP2E1PstI/RsaI polymorphism and interaction with tobacco, alcohol and GSTs in gastric cancer susceptibility: A meta-analysis of the literature
artículo científico publicado en 2006
Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia.
artículo científico publicado en 2018
Candidate gene-based association study of antipsychotic-induced movement disorders in long-stay psychiatric patients: a prospective study
artículo científico publicado en 2012
Candidate-gene association study searching for genetic factors involved in migraine chronification
artículo científico publicado en 2014
Case-control study of risk factors of Creutzfeldt-Jakob disease in Europe during 1993-95. European Union (EU) Collaborative Study Group of Creutzfeldt-Jakob disease (CJD).
artículo científico publicado en 1998
Cataract surgery and the risk of aging macula disorder: the rotterdam study
artículo científico publicado en 2008
Cathepsin D (C224T) polymorphism in sporadic and genetic Creutzfeldt-Jakob disease
artículo científico publicado en 2010
Cathepsin D gene and the risk of Alzheimer's disease: a population-based study and meta-analysis.
artículo científico publicado en 2009
Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility to fracture in the elderly
artículo científico publicado en 2003
Cerebral small vessel disease genomics and its implications across the lifespan
artículo científico publicado en 2020
Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias: a longitudinal multicentre study over 10 years
artículo científico publicado en 2012
Cerebrospinal fluid biomarkers in human genetic transmissible spongiform encephalopathies
artículo científico publicado en 2009
Cerebrovascular risk factors do not contribute to genetic variance of cognitive function: the ERF study
artículo científico
Characteristics of de novo structural changes in the human genome
artículo científico publicado en 2015
Characterization of pathogenic SORL1 genetic variants for association with Alzheimer's disease: a clinical interpretation strategy
artículo científico publicado en 2017
Cholesterol and age-related macular degeneration: is there a link?
artículo científico publicado en 2004
Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies
artículo científico publicado en 2018
Circulating metabolites are associated with brain atrophy and white matter hyperintensities
artículo científico publicado en 2020
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals
artículo científico publicado en 2009
Clinical Implications of Old and New Genes for Open-Angle Glaucoma
article
Clinical features and mortality in patients with early-onset Alzheimer's disease
artículo científico publicado en 1996
Clinical features and neuroimaging of PARK7-linked parkinsonism
artículo científico publicado en 2003
Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture
artículo científico publicado en 2009
Common DNA variants predict tall stature in Europeans
artículo científico publicado en 2013
Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities
artículo científico publicado en 2020
Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families
article by Padhraig Gormley et al published September 2018 in Neuron
Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval
Common genetic determinants of intraocular pressure and primary open-angle glaucoma
artículo científico publicado en 2012
Common genetic variants associate with serum phosphorus concentration
artículo científico publicado en 2010
Common genetic variants associated with cognitive performance identified using the proxy-phenotype method
artículo científico publicado en 2014
Common genetic variants associated with open-angle glaucoma
artículo científico publicado en 2011
Common genetic variants influence human subcortical brain structures
artículo científico publicado en 2015
Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium
artículo científico publicado en 2011
Common polygenic variation enhances risk prediction for Alzheimer's disease
artículo científico publicado en 2015
Common variants associated with plasma triglycerides and risk for coronary artery disease
artículo científico publicado en 2013
Common variants at 12q14 and 12q24 are associated with hippocampal volume
artículo científico publicado en 2012
Common variants at 12q15 and 12q24 are associated with infant head circumference
artículo científico publicado en 2012
Common variants at 2q11.2, 8q21.3, and 11q13.2 are associated with major mood disorders.
artículo científico publicado en 2017
Common variants at 6q22 and 17q21 are associated with intracranial volume
artículo científico publicado en 2012
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
artículo científico publicado en 2011
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction
artículo científico publicado en 2010
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
artículo científico publicado en 2021
Common variants in Mendelian kidney disease genes and their association with renal function
artículo científico publicado en 2013
Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis
scientific article published on 24 October 2008
Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration
artículo científico publicado en 2011
Comparison of participant information and informed consent forms of five European studies in genetic isolated populations
artículo científico publicado en 2010
Complement component C3 and risk of age-related macular degeneration
artículo científico publicado en 2009
Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration
artículo científico publicado en 2006
Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies
artículo científico publicado en 2014
Consanguineous marriages, pearls and perils: Geneva International Consanguinity Workshop Report
artículo científico publicado en 2011
Constant transmission properties of variant Creutzfeldt-Jakob disease in 5 countries
artículo científico publicado en 2012
Correction. Heritability and genome-wide association analyses of intracranial carotid artery calcification: The Rotterdam Study
artículo científico publicado en 2016
Correction: Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation In Vivo.
artículo científico publicado en 2010
Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.
artículo científico publicado en 2009
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults
artículo científico publicado en 2017
Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study
artículo científico publicado en 2015
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
artículo científico publicado en 2016
Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation
artículo científico publicado en 2019
Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
artículo científico publicado en 2016
Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis
artículo científico publicado en 2015
Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
scholarly article published in Nature Genetics
Creutzfeldt-Jakob disease 38 years after diagnostic use of human growth hormone
artículo científico publicado en 2002
Creutzfeldt-Jakob disease: diagnosis, incidence, prevention and treatment
artículo científico publicado en 2002
Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
artículo científico publicado en 2018
Cyclin-dependent kinase 5 is associated with risk for Alzheimer's disease in a Dutch population-based study
artículo científico publicado en 2008
DNA methylation is associated with lung function in never smokers
scientific article published on 02 December 2019
DNA methylation signatures of educational attainment
artículo científico publicado en 2018
Decreased DNA repair capacity in familial, but not in sporadic Alzheimer's disease
artículo científico publicado en 1991
Defining the role of common variation in the genomic and biological architecture of adult human height
artículo científico publicado en 2014
Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency
artículo científico publicado en 2013
Delirium in the Acute Phase After Stroke and the Role of the Apolipoprotein E Gene
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artículo científico publicado el 19 de agosto de 2013
Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric
artículo científico publicado en 2002
Descriptive epidemiology of Creutzfeldt-Jakob disease in six European countries, 1993-1995. EU Collaborative Study Group for CJD.
artículo científico publicado en 1998
Detecting low frequent loss-of-function alleles in genome wide association studies with red hair color as example
artículo científico publicado en 2011
Determinants of DNA yield and purity collected with buccal cell samples
scientific article published on 17 September 2009
Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease
artículo científico publicado en 2006
Determining Possible Shared Genetic Architecture Between Myopia and Primary Open-Angle Glaucoma
scientific article published on 01 July 2019
Development and application of genomic control methods for genome-wide association studies using non-additive models
artículo científico publicado en 2013
Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia
artículo científico publicado en 2016
Direct-to-Consumer Personal Genome Testing for Age-Related Macular Degeneration
article
Directional dominance on stature and cognition in diverse human populations
artículo científico publicado en 2015
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation
artículo científico publicado en 2015
Discovery and fine mapping of serum protein loci through transethnic meta-analysis
artículo científico publicado en 2012
Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing
artículo científico publicado en 2017
Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps
artículo científico publicado en 2016
Discovery and refinement of loci associated with lipid levels
artículo científico publicado en 2013
Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease
artículo científico publicado en 2012
Discovery of novel heart rate-associated loci using the Exome Chip
artículo científico publicado en 2017
Disease variants alter transcription factor levels and methylation of their binding sites
artículo científico publicado en 2016
Disentangling the biological pathways involved in early features of Alzheimer's disease in the Rotterdam Study
artículo científico publicado en 2018
Disentangling the genetics of lean mass
article
Distinguishing true from false positives in genomic studies: p values
artículo científico publicado en 2013
Diuretic–gene interaction and the risk of myocardial infarction and stroke
article
Does bilirubin protect against hemochromatosis gene (HFE) related mortality?
artículo científico publicado en 2004
Dominant hemochromatosis due to N144H mutation of SLC11A3: clinical and biological characteristics
artículo científico publicado en 2002
Drug-gene interaction between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and antihypertensive therapy
scientific article published on 31 January 2006
Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval
artículo científico publicado en 2013
Drug-gene interactions between genetic polymorphisms and antihypertensive therapy
artículo científico publicado en 2004
EIF2AK3 variants in Dutch patients with Alzheimer's disease
artículo científico publicado en 2018
EVI5 is a risk gene for multiple sclerosis
article
Early Age at Menopause is Associated with Increased risk of Dementia and Mortality in Women with Down Syndrome
artículo científico publicado en 2010
Early cognitive decline is associated with prion protein codon 129 polymorphism
artículo científico publicado en 2003
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials
artículo científico publicado en 2011
Effect of the APOE-491A/T promoter polymorphism on apolipoprotein E levels and risk of Alzheimer disease: The Rotterdam Study
artículo científico publicado en 2002
Effectiveness of HMG-CoA reductase inhibitors is modified by the ACE insertion deletion polymorphism
artículo científico publicado en 2004
Effectiveness of statins in the reduction of the risk of myocardial infarction is modified by the GNB3 C825T variant
scientific article published on 01 July 2008
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
artículo científico publicado en 1997
Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations
artículo científico publicado en 2014
Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes
artículo científico publicado en 2015
Effects of the Renin-Angiotensin System Genes and Salt Sensitivity Genes on Blood Pressure and Atherosclerosis in the Total Population and Patients With Type 2 Diabetes
article
Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies
artículo científico publicado en 2011
Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide
artículo científico publicado en 2008
Eleven years of autopsy on account of Creutzfeldt-Jakob disease in the Netherlands
artículo científico publicado en 2009
Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders
artículo científico publicado en 2001
Epidemiology of Alzheimer's Disease
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artículo científico publicado el 1 de enero de 1992
Epidemiology of neurological diseases in elderly people: what did we learn from the Rotterdam Study?
scientific article published on 01 June 2006
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
artículo científico publicado en 2016
Epistatic Effect of Cholesteryl Ester Transfer Protein and Hepatic Lipase on Serum High-Density Lipoprotein Cholesterol Levels
artículo científico publicado en 2007
Erratum: Common variants at 12q15 and 12q24 are associated with infant head circumference
scholarly article published in Nature Genetics
Erratum: Common variants at 6q22 and 17q21 are associated with intracranial volume
article
Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses
article
Erratum: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
artículo científico publicado en 2016
Erratum: Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms
article
Erratum: Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence
artículo científico publicado en 2017
Erratum: Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia
article
Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
artículo científico publicado en 2017
Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
artículo científico publicado en 2011
Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
artículo científico publicado en 2010
Estimating human age from T-cell DNA rearrangements
article
Estrogen receptor alpha gene haplotype is associated with radiographic osteoarthritis of the knee in elderly men and women
artículo científico publicado en 2003
Estrogen receptor alpha gene polymorphisms associated with incident aging macula disorder
artículo científico publicado en 2007
Estrogen receptor alpha polymorphisms and postmenopausal breast cancer risk
artículo científico publicado en 2007
Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women
artículo científico publicado en 2006
Estrogen use and early onset Alzheimer's disease: a population-based study
artículo científico publicado en 1999
European lactase persistence genotype shows evidence of association with increase in body mass index
artículo científico publicado en 2009
Evaluation of Presumably Disease Causing SCN1A Variants in a Cohort of Common Epilepsy Syndromes
artículo científico publicado en 2016
Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia
Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease
artículo científico publicado en 2016
Evaluation of risk prediction updates from commercial genome-wide scans
article by Raluca Mihaescu et al published 25 July 2009 in Genetics in Medicine
Evaluation of the Myocilin Mutation Gln368Stop Demonstrates Reduced Penetrance for Glaucoma in European Populations
artículo científico publicado en 2016
Evidence for allelic heterogeneity in familial early-onset Alzheimer's disease
scientific article published on 01 April 1991
Evidence for major gene inheritance of Alzheimer disease in families of patients with and without apolipoprotein E epsilon 4
artículo científico publicado en 1996
Evidence for novel loci for late-onset Parkinson’s disease in a genetic isolate from the Netherlands
article
Evidence of inbreeding depression on human height
artículo científico publicado en 2012
Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene
artículo científico publicado en 2005
Exome Chip Analysis Identifies Low-Frequency a on Brain Magnetic Imaging
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits
artículo científico publicado en 2016
Exome Sequencing Analysis Identifies Rare Variants in ATM and RPL8 That Are Associated With Shorter Telomere Length
scientific article published on 30 April 2020
Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation-differentiation balance early in life and optic nerve degeneration at old age.
artículo científico publicado en 2013
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology
artículo científico publicado en 2019
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology
scientific article published on 01 September 2019
Exome-Wide Meta-Analysis Identifies Rare 3'-UTR Variant in ERCC1/CD3EAP Associated with Symptoms of Sleep Apnea
artículo científico publicado en 2017
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6
Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms.
artículo científico publicado en 2016
ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals
Expression and Gene Variation Studies Deny Association of Human HSD3B1 Gene With Aldosterone Production or Blood Pressure
article
Expression of type III hyperlipoproteinemia in apolipoprotein E2 (Arg158 --> Cys) homozygotes is associated with hyperinsulinemia
artículo científico publicado en 2002
FTO genotype is associated with phenotypic variability of body mass index
artículo científico publicado en 2012
Familial Aggregation of Alzheimer's Disease and Related Disorders: A Collaborative Re-Analysis of Case-Control Studies
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artículo científico publicado el 1 de enero de 1991
Familial aggregation in frontotemporal dementia
artículo científico publicado en 1998
Familial aggregation of preeclampsia and intrauterine growth restriction in a genetically isolated population in The Netherlands
artículo científico publicado en 2008
Familial aggregation, the PDE4D gene, and ischemic stroke in a genetically isolated population
artículo científico publicado en 2005
Familial clustering and genetic risk for dementia in a genetically isolated Dutch population
artículo científico publicado en 2004
Familial clustering of multiple sclerosis in a Dutch genetic isolate
Familial forms of fronto-temporal dementia
artículo científico publicado en 1995
Family score as an indicator of genetic risk of primary open-angle glaucoma
artículo científico publicado en 2002
Fast LC-ESI-MS/MS analysis and influence of sampling conditions for gut metabolites in plasma and serum
scientific article published on 26 August 2019
Fifteen Genetic Loci Associated With the Electrocardiographic P Wave
artículo científico publicado en 2017
Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C
artículo científico publicado en 2015
Fine-mapping the effects of Alzheimer's disease risk loci on brain morphology
artículo científico publicado en 2016
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects
artículo científico publicado en 2013
Five genetic variants associated with prostate cancer
scientific article published on 01 June 2008
Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene
artículo científico publicado en 2014
Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo
artículo científico publicado en 2010
From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function
article published in 2018
From gene to disease; presenilins and Alzheimer disease
artículo científico publicado en 2002
Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study
artículo científico publicado en 2003
GENESTAT: an information portal for design and analysis of genetic association studies
artículo científico publicado en 2009
GWAS and Meta-Analysis in Aging/Longevity
artículo científico publicado en 2015
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
artículo científico publicado en 2018
GWAS for executive function and processing speed suggests involvement of the CADM2 gene.
artículo científico publicado en 2015
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
artículo científico publicado en 2013
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy
artículo científico publicado en 2014
GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI
artículo científico publicado en 2019
GenABEL: an R library for genome-wide association analysis
artículo científico publicado en 2007
Gene co-expression analysis identifies brain regions and cell types involved in migraine pathophysiology: a GWAS-based study using the Allen Human Brain Atlas
artículo científico publicado en 2016
Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia
artículo científico publicado en 2014
Gene-based pleiotropy across migraine with aura and migraine without aura patient groups
artículo científico publicado en 2015
Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci
artículo científico publicado en 2014
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
scientific article published on 05 May 2020
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease
artículo científico publicado en 2014
Genes predict village of origin in rural Europe
artículo científico publicado en 2010
Genes, pathways, and animal models in primary open-angle glaucoma
artículo científico publicado en 2015
Genetic African Ancestry Is Associated With Central Corneal Thickness and Intraocular Pressure in Primary Open-Angle Glaucoma
artículo científico publicado en 2017
Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide
scholarly article published 28 August 2017
Genetic Association of Apolipoprotein E with Age-Related Macular Degeneration
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artículo científico publicado el 1 de julio de 1998
Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium
article published in 2018
Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation
artículo científico publicado en 2020
Genetic Determinants of Unruptured Intracranial Aneurysms in the General Population
artículo científico publicado en 2015
Genetic Epidemiology of Alzheimer Disease
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artículo científico publicado el 1 de enero de 1997
Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus
artículo científico publicado en 2020
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity
scientific article published on 11 September 2020
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project
artículo científico publicado en 2018
Genetic adaptation of fatty-acid metabolism: a human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids
artículo científico publicado en 2012
Genetic analysis for a shared biological basis between migraine and coronary artery disease
artículo científico publicado en 2015
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
scientific article published on 17 September 2018
Genetic analysis of over one million people identifies 535 novel loci for blood pressure
Genetic and environmental factors in Alzheimer's disease
artículo científico publicado en 1999
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting
Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia
artículo científico publicado en 2002
Genetic architecture of circulating lipid levels
artículo científico publicado en 2011
Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity
Genetic architecture of open angle glaucoma and related determinants
artículo científico publicado en 2010
Genetic architecture of plasma adiponectin overlaps with the genetics of metabolic syndrome-related traits
artículo científico publicado en 2010
Genetic architecture of subcortical brain structures in 38,851 individuals
scientific article published on 21 October 2019
Genetic association of the presenilin-1 regulatory region with early-onset Alzheimer's disease in a population-based sample
artículo científico publicado en 1999
Genetic association studies: genes in search of diseases
artículo científico publicado en 2002
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
artículo científico publicado en 2014
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
artículo científico publicado en 2016
Genetic contributions to glaucoma: heritability of intraocular pressure, retinal nerve fiber layer thickness, and optic disc morphology
artículo científico publicado en 2007
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).
artículo científico publicado en 2015
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults
scientific article published on 22 September 2020
Genetic determinants of circulating sphingolipid concentrations in European populations
scientific article published on 02 October 2009
Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins
artículo científico publicado en 2009
Genetic evidence of assortative mating in humans
scholarly article
Genetic factors and insulin secretion: gene variants in the IGF genes
artículo científico publicado en 2004
Genetic factors influence the clustering of depression among individuals with lower socioeconomic status
artículo científico publicado en 2009
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
artículo científico publicado en 2015
Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration
artículo científico publicado en 2013
Genetic loci for coronary calcification and serum lipids relate to aortic and carotid calcification
artículo científico publicado en 2012
Genetic loci for retinal arteriolar microcirculation
artículo científico publicado en 2013
Genetic loci for serum lipid fractions and intracerebral hemorrhage
artículo científico publicado en 2016
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
artículo científico publicado en 2019
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus
artículo científico publicado en 2015
Genetic polymorphisms and heart failure
artículo científico publicado en 2004
Genetic prion disease: the EUROCJD experience
artículo científico publicado en 2005
Genetic risk of Parkinson's disease in the general population
artículo científico publicado en 2016
Genetic risk of age-related maculopathy. Population-based familial aggregation study
artículo científico publicado en 1998
Genetic risk of neurodegenerative diseases is associated with mild cognitive impairment and conversion to dementia
artículo científico publicado en 2015
Genetic risk profiles for depression and anxiety in adult and elderly cohorts
artículo científico publicado en 2010
Genetic scoring analysis: a way forward in genome wide association studies?
artículo científico publicado en 2009
Genetic screening for common mutations: lessons from hereditary hemochromatosis
scientific article published on 01 January 2003
Genetic studies of body mass index yield new insights for obesity biology
artículo científico publicado en 2015
Genetic susceptibility to multiple sclerosis: Brain structure and cognitive function in the general population
artículo científico publicado en 2016
Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations
artículo científico publicado en 2013
Genetic testing has no place as a routine diagnostic test in sporadic and familial cases of Alzheimer's disease
artículo científico publicado en 2004
Genetic testing should not be advocated as a diagnostic tool in familial forms of dementia
artículo científico publicado en 2000
Genetic transmission of Alzheimer's disease among families in a Dutch population based study
artículo científico publicado en 1993
Genetic variability in the regulatory region of presenilin 1 associated with risk for Alzheimer's disease and variable expression
artículo científico publicado en 2000
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data
artículo científico publicado en 2009
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
artículo científico publicado en 2016
Genetic variants in RBFOX3 are associated with sleep latency
artículo científico publicado en 2016
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
artículo científico publicado en 2011
Genetic variants influencing circulating lipid levels and risk of coronary artery disease
artículo científico publicado en 2010
Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images
Genetic variation associated with circulating monocyte count in the eMERGE Network
artículo científico publicado en 2013
Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility
artículo científico publicado en 2010
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
scientific journal article
Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis
scientific journal article
Genetic variation in the fibrinogen-alpha and fibrinogen-gamma genes in relation to arterial stiffness: the Rotterdam Study
artículo científico publicado en 2009
Genetic variation in the renin--angiotensin system, use of renin--angiotensin system inhibitors and the risk of myocardial infarction
scientific article published on 16 December 2010
Genetic variation in the renin-angiotensin system and arterial stiffness. The Rotterdam Study
artículo científico publicado en 2009
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
artículo científico publicado en 2011
Genetic variation underlying cognition and its relation with neurological outcomes and brain imaging
Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach
scientific article published on 12 February 2011
Genetics of the human metabolome, what is next?
artículo científico publicado en 2014
Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels
artículo científico publicado en 2015
Genome-Wide Association Study of Vascular Dementia
scholarly article by Elisabeth M.C. Schrijvers et al published February 2012 in Stroke Journal
Genome-based prediction of breast cancer risk in the general population: a modeling study based on meta-analyses of genetic associations
artículo científico publicado en 2011
Genome-based prediction of common diseases: advances and prospects
artículo científico publicado en 2008
Genome-based prediction of common diseases: methodological considerations for future research
artículo científico publicado en 2009
Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length
scientific article published on 27 February 2020
Genome-wide Association Study Links APOEϵ4 and BACE1 Variants with Plasma Amyloid β Levels
Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals
scientific article published on 01 July 2019
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis
artículo científico publicado en 2016
Genome-wide analyses of borderline personality features
artículo científico publicado en 2014
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
artículo científico publicado en 2016
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course
artículo científico publicado en 2013
Genome-wide analysis of genetic loci associated with Alzheimer disease
artículo científico publicado en 2010
Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma
artículo científico publicado en 2014
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
artículo científico publicado en 2013
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus
artículo científico publicado en 2013
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
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artículo científico publicado en 2022
Genome-wide association analysis identifies multiple loci related to resting heart rate
artículo científico publicado en 2010
Genome-wide association analysis identifies susceptibility loci for migraine without aura
artículo científico publicado en 2012
Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM
artículo científico publicado en 2011
Genome-wide association analysis on five isolated populations identifies variants of the HLA-DOA gene associated with white wine liking
artículo científico publicado en 2015
Genome-wide association and functional follow-up reveals new loci for kidney function
artículo científico publicado en 2012
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption
scientific journal article
Genome-wide association meta-analysis for total serum bilirubin levels
artículo científico publicado en 2009
Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error
artículo científico publicado en 2018
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits
artículo científico publicado en 2019
Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence
artículo científico publicado en 2017
Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity
Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error
artículo científico publicado en 2020
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.
artículo científico publicado en 2014
Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability
artículo científico publicado en 2018
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution
artículo científico publicado en 2009
Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area
article
Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium
artículo científico publicado en 2009
Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium
artículo científico publicado en 2011
Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels
artículo científico publicado en 2010
Genome-wide association study for acute otitis media in children identifies FNDC1 as disease contributing gene
artículo científico publicado en 2016
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction
artículo científico publicado en 2011
Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium
artículo científico publicado en 2014
Genome-wide association study identifies 48 common genetic variants associated with handedness
artículo científico publicado en 2020
Genome-wide association study identifies 74 loci associated with educational attainment
artículo científico publicado en 2016
Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
artículo científico publicado en 2011
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma
artículo científico publicado en 2011
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels
artículo científico publicado en 2015
Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations
artículo científico publicado en 2012
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
artículo científico publicado en 2011
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region
artículo científico publicado en 2013
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume
artículo científico publicado en 2018
Genome-wide association study of PR interval
artículo científico publicado en 2010
Genome-wide association study of blood pressure and hypertension
scientific journal article
Genome-wide association study of intracranial aneurysm identifies three new risk loci
artículo científico publicado en 2010
Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.
artículo científico publicado en 2010
Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations
scientific article published on 13 October 2018
Genome-wide association study of retinopathy in individuals without diabetes
artículo científico publicado en 2013
Genome-wide association study of smoking initiation and current smoking
artículo científico publicado en 2009
Genome-wide association study on the FEV1/FVC ratio in never-smokers identifies HHIP and FAM13A.
artículo científico publicado en 2016
Genome-wide associations for birth weight and correlations with adult disease
artículo científico publicado en 2016
Genome-wide identification of directed gene networks using large-scale population genomics data
scientific article published in Nature Communications
Genome-wide linkage analysis of serum creatinine in three isolated European populations.
artículo científico publicado en 2009
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia
artículo científico publicado en 2013
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
artículo científico publicado en 2017
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
scientific journal article
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
artículo científico publicado en 2012
Genome-wide meta-analysis identifies new susceptibility loci for migraine
artículo científico publicado en 2013
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption
artículo científico publicado en 2014
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
artículo científico publicado en 2017
Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci
artículo científico publicado en 2014
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
artículo científico publicado en 2016
Genome-wide patterns and properties of de novo mutations in humans
artículo científico publicado en 2015
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults
artículo científico publicado en 2017
Genome-wide profiling of blood pressure in adults and children
artículo científico publicado en 2011
Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.
artículo científico publicado en 2016
Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk
scientific journal article
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
artículo científico publicado en 2014
Genomewide association studies of stroke
artículo científico publicado en 2009
Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
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artículo científico publicado en 2016
Genomewide scan for affective disorder susceptibility Loci in families of a northern Swedish isolated population
artículo científico publicado en 2004
Genome‐wide meta‐analysis of late‐onset Alzheimer’s disease using rare variant imputation in 65,602 subjects identifies risk loci with roles in memory, neurodevelopment, and cardiometabolic traits: The international genomics of Alzheimer’s project (
artículo científico publicado en 2020
Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium
artículo científico publicado en 2010
Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression.
artículo científico publicado en 2006
Glucocorticoid receptor-9beta polymorphism is associated with systolic blood pressure and heart growth during early childhood. The Generation R Study
scientific article published on 13 December 2010
Good prospects for genetic and molecular epidemiologic studies in the European Journal of Epidemiology
scientific article published on 01 January 2003
Gray matter heritability in family-based and population-based studies using voxel-based morphometry
artículo científico publicado en 2017
Gut microbiome-wide association study of depressive symptoms
HFE gene mutations increase the risk of coronary heart disease in women.
artículo científico publicado en 2010
HFE variants, APOE and Alzheimer's disease: Findings from the population-based Rotterdam Study
scholarly article by B.Z. Alizadeh et al published February 2009 in Neurobiology of Aging
Haplotype analyses of the APOA5 gene in patients with familial combined hyperlipidemia
article
Haplotype reference consortium panel: Practical implications of imputations with large reference panels
artículo científico publicado en 2017
Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research
artículo científico publicado en 2016
Head trauma and risk of dementia and Alzheimer's disease: The Rotterdam Study
artículo científico publicado en 1999
Head trauma and the risk of Alzheimer's disease
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artículo científico publicado el 1 de abril de 1992
Head trauma as a risk factor for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group
scientific article published on 01 January 1991
Hereditary frontotemporal dementia is linked to chromosome 17q21?q22: A genetic and clinicopathological study of three dutch families
artículo científico publicado en 1997
Heritabilities, apolipoprotein E, and effects of inbreeding on plasma lipids in a genetically isolated population: the Erasmus Rucphen Family Study
artículo científico publicado en 2007
Heritabilities, proportions of heritabilities explained by GWAS findings, and implications of cross-phenotype effects on PR interval
artículo científico publicado en 2015
Heritability and Genome-Wide Association Analyses of Human Gait Suggest Contribution of Common Variants
artículo científico publicado en 2015
Heritability and Genome-Wide Association Analyses of Intracranial Carotid Artery Calcification: The Rotterdam Study
artículo científico publicado en 2016
Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes
scientific journal article
Heritability and genome-wide associations studies of cerebral blood flow in the general population
artículo científico publicado en 2017
Heritability estimates for 361 blood metabolites across 40 genome-wide association studies
artículo científico publicado en 2020
Heritability of Serum Iron, Ferritin and Transferrin Saturation in a Genetically Isolated Population, the Erasmus Rucphen Family (ERF) Study
Heritability of blood pressure traits and the genetic contribution to blood pressure variance explained by four blood-pressure-related genes
artículo científico publicado en 2007
Heritability of dietary food intake patterns
artículo científico publicado en 2012
Heritability of fasting glucose levels in a young genetically isolated population
artículo científico publicado en 2006
Heritability of the Function and Structure of the Arterial Wall
Heritability of the shape of subcortical brain structures in the general population
artículo científico publicado en 2016
Heterogeneity of the genetic risk in age-related macular disease
scientific article published on 01 March 2005
Hippocampal, amygdalar, and global brain atrophy in different apolipoprotein E genotypes
artículo científico publicado en 2002
History of dementia and Parkinson's disease in 1st-degree relatives of patients with Alzheimer's disease
artículo científico publicado en 1989
Human age estimation from blood using mRNA, DNA methylation, DNA rearrangement, and telomere length
artículo científico publicado en 2016
Human prion diseases in the Netherlands (1998-2009): clinical, genetic and molecular aspects
artículo científico publicado en 2012
Human spongiform encephalopathies in the Netherlands
artículo científico publicado en 2009
Human transmissible spongiform encephalopathies in eleven countries: diagnostic pattern across time, 1993-2002.
artículo científico publicado en 2006
Hundreds of variants clustered in genomic loci and biological pathways affect human height
artículo científico publicado en 2010
IGF-I gene promoter polymorphism is a predictor of survival after myocardial infarction in patients with type 2 diabetes
artículo científico publicado en 2006
Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis
artículo científico publicado en 2008
Identification of Srp9 as a febrile seizure susceptibility gene
artículo científico publicado en 2014
Identification of a candidate gene for astigmatism
scientific journal article
Identification of a common variant at the NOS1AP locus strongly associated to QT-interval duration
artículo científico publicado en 2008
Identification of a rare coding variant in complement 3 associated with age-related macular degeneration
artículo científico publicado en 2013
Identification of context-dependent expression quantitative trait loci in whole blood
artículo científico publicado en 2016
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
artículo científico publicado en 2013
Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study
scientific article published on 16 September 2020
Identification of seven loci affecting mean telomere length and their association with disease
artículo científico publicado en 2013
Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach
artículo científico publicado en 2014
Igf-I bioactivity in an elderly population: relation to insulin sensitivity, insulin levels, and the metabolic syndrome
artículo científico publicado en 2010
Ignoring distant genealogic loops leads to false-positives in homozygosity mapping
artículo científico publicado en 2006
Impact of cumulative SBP and serious adverse events on efficacy of intensive blood pressure treatment: a randomized clinical trial
scientific article published on 01 May 2019
Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'.
artículo científico publicado en 2014
Improvement of Risk Prediction by Genomic Profiling: Reclassification Measures Versus the Area Under the Receiver Operating Characteristic Curve
article by Raluca Mihaescu et al published 18 June 2010 in American Journal of Epidemiology
In memoriam: Leena Peltonen-Palotie (1952–2010).
artículo científico publicado en 2010
In search of genes involved in neurodegenerative disorders
artículo científico publicado en 2005
Increased High Density Lipoprotein-levels associated with Age-related Macular degeneration. Evidence from the EYE-RISK and E3 Consortia
article by J M Colijn et al published 10 October 2018 in Ophthalmology
Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration
article published in 2019
Increasing Prevalence of Myopia in Europe and the Impact of Education
artículo científico publicado en 2015
Independent Multiple Factor Association Analysis for Multiblock Data in Imaging Genetics
scientific article published on 01 October 2019
Infant feeding and childhood cancer
scientific article published on 01 October 1988
Infectious mononucleosis-linked HLA class I single nucleotide polymorphism is associated with multiple sclerosis
artículo científico publicado en 2010
Influence of the prion protein and the apolipoprotein E genotype on the Creutzfeldt-Jakob Disease phenotype
artículo científico publicado en 2001
Influence of timing on CSF tests value for Creutzfeldt-Jakob disease diagnosis
scientific article published on 25 March 2007
Insertion/deletion polymorphism of the ACE gene and adherence to ACE inhibitors
artículo científico publicado en 2005
Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses
artículo científico publicado en 2015
Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis
artículo científico publicado en 2013
Insulin VNTR and IGF-1 promoter region polymorphisms are not associated with body composition in early childhood: the generation R study.
artículo científico publicado en 2010
Insulin gene variable number of tandem repeats is not associated with weight from fetal life until infancy: the Generation R Study
artículo científico publicado en 2007
Insulin-like growth factor I gene promoter polymorphism, collagen type II alpha1 (COL2A1) gene, and the prevalence of radiographic osteoarthritis: the Rotterdam Study
artículo científico publicado en 2004
Insulin-like growth factor I promoter polymorphism, risk of stroke, and survival after stroke: the Rotterdam study
artículo científico publicado en 2006
Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study)
scientific article published on 01 August 2004
Insulin-like growth factor-I receptor stimulating activity is associated with dementia
artículo científico publicado en 2014
Insulin-resistance and metabolic syndrome are related to executive function in women in a large family-based study
artículo científico publicado en 2010
Integrating metabolomics, genomics and disease pathways in age-related macular degeneration: The EYE-RISK Consortium
scientific article published on 14 June 2020
Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas
scientific article published on 13 January 2020
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function
artículo científico publicado en 2012
Intensity of human prion disease surveillance predicts observed disease incidence
artículo científico publicado en 2013
Interaction between hypertension, apoE, and cerebral white matter lesions
artículo científico publicado en 2004
Interaction between polymorphisms in the renin–angiotensin–system and angiotensin-converting enzyme inhibitor or β-blocker use and the risk of myocardial infarction and stroke
Interaction between the Gly460Trp alpha-adducin gene variant and diuretics on the risk of myocardial infarction
artículo científico
Interaction between the vitamin D receptor gene and collagen type Ialpha1 gene in susceptibility for fracture.
artículo científico publicado en 2001
Interaction of insulin and PPAR-α genes in Alzheimer's disease: the Epistasis Project
artículo científico publicado en 2011
Interactions between PPAR-α and inflammation-related cytokine genes on the development of Alzheimer's disease, observed by the Epistasis Project
artículo científico publicado en 2012
Interactions between dietary vitamin E intake and SIRT1 genetic variation influence body mass index.
artículo científico publicado en 2010
Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies
artículo científico publicado en 2010
Interferon gamma receptor 2 gene variants are associated with liver fibrosis in the general population: the Rotterdam Study
artículo científico publicado en 2014
Interleukin 6 -174 g/c promoter polymorphism and risk of coronary heart disease: results from the rotterdam study and a meta-analysis
scientific article published on 03 November 2005
Interleukin 6 G-174 C polymorphism and breast cancer risk
artículo científico publicado en 2006
Interleukin-1 gene cluster variants with innate cytokine production profiles and osteoarthritis in subjects from the Genetics, Osteoarthritis and Progression Study
artículo científico publicado en 2010
International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents
artículo científico publicado en 2016
Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study
artículo científico publicado en 2016
Investigation of the association of the CRTM and CRTL1 genes with radiographically evident osteoarthritis in subjects from the Rotterdam study
artículo científico publicado en 1997
Is Alzheimer's disease distinct from normal ageing?
scientific article published on 01 July 1988
Is genetic screening for hemochromatosis worthwhile?
artículo científico publicado en 2004
Is parental age related to the risk of Alzheimer's disease?
artículo científico publicado en 1990
LPIN2 Is Associated With Type 2 Diabetes, Glucose Metabolism, and Body Composition
article
Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study
artículo científico publicado en 2008
Large common deletions associate with mortality at old age.
artículo científico publicado en 2011
Large meta-analysis establishes the ACE insertion-deletion polymorphism as a marker of Alzheimer's disease
artículo científico publicado en 2005
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
artículo científico publicado en 2017
Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium
artículo científico publicado en 2012
Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair
artículo científico publicado en 2015
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.
artículo científico publicado en 2017
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
artículo científico publicado en 2012
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
artículo científico publicado en 2012
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
artículo científico publicado en 2015
Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
scientific article published on 03 April 2019
Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels
artículo científico publicado en 2018
Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers
artículo científico publicado en 2014
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects
artículo científico publicado en 2018
Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population
artículo científico publicado en 2019
Linkage analysis and whole exome sequencing identify a novel candidate gene in a Dutch multiple sclerosis family
artículo científico publicado en 2018
Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates Aβ-40 levels to presenilin 2
artículo científico publicado en 2012
Linkage analysis of adult height in a large pedigree from a Dutch genetically isolated population
artículo científico publicado en 2009
Linkage and association analyses of glaucoma related traits in a large pedigree from a Dutch genetically isolated population
Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample
artículo científico publicado en 2005
Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene
artículo científico publicado en 2009
Linkage disequilibrium in young genetically isolated Dutch population
article
Lipidomic profiling identifies signatures of metabolic risk
artículo científico publicado en 2019
Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies
artículo científico publicado en 2013
Localization of autosomal recessive early-onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset
artículo científico publicado en 2002
Loci influencing blood pressure identified using a cardiovascular gene-centric array
artículo científico publicado en 2013
Loci influencing blood pressure identified using a cardiovascular gene-centric array.
artículo científico publicado en 2013
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
artículo científico publicado en 2009
Long-term Air Pollution Exposure, Genome-wide DNA Methylation and Lung Function in the LifeLines Cohort Study
artículo científico publicado en 2018
Longevity candidate genes and their association with personality traits in the elderly
artículo científico publicado en 2011
Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability.
artículo científico publicado en 2019
Low frequency and rare coding variation contributes to multiple sclerosis risk
Low-density lipoprotein receptor mutations generate synthetic genome-wide associations
artículo científico publicado en 2012
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
artículo científico publicado en 2015
Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations
artículo científico publicado en 2002
Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies
artículo científico publicado en 2006
Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease
article
Maternal Transmission of Multiple Sclerosis in a Dutch Population
article
Maternal age and Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group
artículo científico publicado en 1991
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
artículo científico publicado en 2019
Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report)
scientific article published on 27 February 2020
Medical and environmental risk factors for sporadic frontotemporal dementia: a retrospective case-control study
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artículo científico publicado el 1 de noviembre de 2003
Medical history and the risk of Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group
artículo científico publicado en 1991
Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes
artículo científico publicado en 2013
Meta- and pooled analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer risk: a huge-GSEC review
artículo científico publicado en 2007
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
artículo científico publicado en 2012
Meta-analyses of genetic studies on major depressive disorder
artículo científico publicado en 2007
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
artículo científico publicado en 2010
Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer
artículo científico publicado en 2008
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
artículo científico publicado en 2010
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci
artículo científico publicado en 2016
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
artículo científico publicado en 2016
Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels
artículo científico publicado en 2016
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
artículo científico publicado en 2013
Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology
artículo científico publicado en 2015
Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium
artículo científico publicado en 2015
Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder
artículo científico publicado en 2015
Meta-analysis of epigenome-wide association studies of cognitive abilities
artículo científico publicado en 2018
Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error
artículo científico publicado en 2016
Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing
Meta-analysis of genome-wide association for migraine in six population-based European cohorts
artículo científico publicado en 2011
Meta-analysis of genome-wide association studies for personality.
artículo científico publicado en 2010
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque
artículo científico publicado en 2011
Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair
artículo científico publicado en 2017
Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking.
artículo científico publicado en 2011
Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process
artículo científico publicado en 2014
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels
artículo científico publicado en 2011
Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error
artículo científico publicado en 2013
Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect
artículo científico publicado en 2013
Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease
artículo científico publicado en 2020
Metabolic network failures in Alzheimer's disease: A biochemical road map.
artículo científico publicado en 2017
Metabolic profiling of intra- and extracranial carotid artery atherosclerosis
artículo científico publicado en 2018
Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls
artículo científico publicado en 2019
Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study
artículo científico
Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium
scientific article published on 12 August 2019
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and susceptibility to gastric adenocarcinoma in an Italian population
artículo científico publicado en 2007
Microbiomics, metabolomics, predicted metagenomics and hepatic steatosis in a population-based study of 1355 adults
artículo científico publicado en 2020
Micronutrients and the risk of lung cancer
artículo científico publicado en 1987
Migraine is not associated with enhanced atherosclerosis
artículo científico publicado en 2012
Migraine without aura: genome-wide association analysis identifies several novel susceptibility.
artículo científico publicado en 2013
Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment
artículo científico publicado en 2004
Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels
artículo científico publicado en 2010
Modulation of genetic associations with serum urate levels by body-mass-index in humans
artículo científico publicado en 2015
Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada
artículo científico publicado en 2005
Mortality in patients with hypertension on angiotensin-I converting enzyme (ACE)-inhibitor treatment is influenced by the ACE insertion/deletion polymorphism
artículo científico publicado en 2005
Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
scientific article published on 21 May 2020
Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits
artículo científico publicado en 2021
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
article
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration
artículo científico publicado en 2019
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
artículo científico publicado en 2019
Multi-trait genome-wide association study identifies new loci associated with optic disc parameters
scientific article published on 27 November 2019
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
artículo científico publicado en 2018
Multicenter cohort association study of SLC2A1 single nucleotide polymorphisms and age-related macular degeneration
artículo científico publicado en 2012
Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI
artículo científico publicado en 2015
Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies
artículo científico publicado en 2014
Multiomics integrative analysis identifies allele-specific blood biomarkers associated to Alzheimer's disease etiopathogenesis
artículo científico publicado en 2021
Multiple etiologies for Alzheimer disease are revealed by segregation analysis.
artículo científico publicado en 1994
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors
artículo científico publicado en 2010
Multiple loci are associated with white blood cell phenotypes
artículo científico publicado en 2011
Multiple loci associated with indices of renal function and chronic kidney disease
scientific journal article
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
artículo científico publicado en 2009
Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression
artículo científico publicado en 2020
Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations
artículo científico publicado en 2022
Mutation analysis of candidate genes within the 2q33.3 linkage area for familial early-onset generalised osteoarthritis.
artículo científico publicado en 2007
Mutation analysis of the chromosome 14q24.3 dihydrolipoyl succinyltransferase (DLST) gene in patients with early-onset Alzheimer disease
artículo científico publicado en 1995
Mutation screening of the tau gene in patients with early-onset Alzheimer's disease
artículo científico publicado en 1999
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
artículo científico publicado en 2003
Mutations in the hemochromatosis gene (HFE) and stroke
artículo científico publicado en 2002
Mutations in the hemochromatosis gene (HFE), Parkinson's disease and parkinsonism
artículo científico publicado en 2003
Myocilin mutations in a population-based sample of cases with open-angle glaucoma: the Rotterdam Study
artículo científico publicado en 2002
N-acetyltransferase-2 polymorphism in Parkinson's disease: the Rotterdam study
artículo científico publicado en 1999
NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium
artículo científico publicado en 2009
Neopterin and the risk of dementia in persons with Down syndrome.
artículo científico publicado en 2009
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals
artículo científico publicado en 2017
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
artículo científico publicado en 2010
New genetic loci link adipose and insulin biology to body fat distribution
artículo científico publicado en 2015
New insights into the genetic etiology of Alzheimer's disease and related dementias
artículo científico publicado en 2022
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
artículo científico publicado en 2012
New loci associated with kidney function and chronic kidney disease
artículo científico publicado en 2010
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
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artículo científico publicado en 2016
Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error
artículo científico publicado en 2013
Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)
No association between the angiotensin-converting enzyme gene and major depression: a case???control study and meta-analysis
article
No evidence for association between tau gene haplotypic variants and susceptibility to Creutzfeldt-Jakob disease
artículo científico publicado en 2007
No evidence for prion protein gene locus multiplication in Creutzfeldt-Jakob disease
artículo científico publicado en 2010
Non-additive genome-wide association scan reveals a new gene associated with habitual coffee consumption
artículo científico publicado en 2016
Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease
scholarly article by Bas A. in 't Veld et al published 22 November 2001 in The New England Journal of Medicine
Nonsynonymous Variation in NKPD1 Increases Depressive Symptoms in European Populations
artículo científico publicado en 2016
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney
artículo científico publicado en 2017
Novel Genetic Loci Associated With Retinal Microvascular Diameter
artículo científico publicado en 2015
Novel Rare Genetic Variants Associated with Airflow Obstruction in the General Population
scientific article published on 01 February 2020
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium
artículo científico publicado en 2010
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
artículo científico publicado en 2018
Novel genetic loci associated with hippocampal volume
scientific article published on 18 January 2017
Novel genetic loci underlying human intracranial volume identified through genome-wide association
artículo científico publicado en 2016
Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis
artículo científico publicado en 2014
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
artículo científico publicado en 2012
Novel parkin mutations detected in patients with early-onset Parkinson's disease
artículo científico publicado en 2005
Novel strategy to identify genetic risk factors for COPD severity: a genetic isolate
artículo científico publicado en 2009
Nucleotide excision DNA repair is associated with age-related vascular dysfunction
artículo científico publicado en 2012
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21
artículo científico publicado en 2006
Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression
scientific article published on 02 April 2019
Occupational exposure to pesticides is associated with differential DNA methylation.
artículo científico publicado en 2018
Occupational exposures to solvents and lead as risk factors for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group
artículo científico publicado en 1991
Octapeptide repeat insertions in the prion protein gene and early onset dementia
artículo científico publicado en 2004
P1-309
PLD3 variants in population studies
artículo científico publicado en 2015
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity
artículo científico publicado en 2018
PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease
artículo científico publicado en 2003
PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION
article
Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults
artículo científico publicado en 2015
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
artículo científico publicado en 2014
Parental family history of dementia in relation to subclinical brain disease and dementia risk
artículo científico publicado en 2017
Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36.
artículo científico publicado en 2001
Partial derivatives meta-analysis: pooled analyses when individual participant data cannot be shared
Pathologically confirmed autoimmune encephalitis in suspected Creutzfeldt-Jakob disease
artículo científico publicado en 2015
Patients with an ApoE epsilon4 allele require lower doses of coumarin anticoagulants
artículo científico publicado en 2005
Ped_Outlier software for automatic identification of within-family outliers
artículo científico publicado en 2010
Perspectives on the use of multiple sclerosis risk genes for prediction
artículo científico publicado en 2011
Pharmacoeconomic evaluation of testing for angiotensin-converting enzyme genotype before starting beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitor therapy in men.
artículo científico publicado en 2004
Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction
artículo científico publicado en 2010
Pharmacogenetic interactions of three candidate gene polymorphisms with ACE-inhibitors or beta-blockers and the risk of atherosclerosis
artículo científico publicado en 2007
Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology
artículo científico publicado en 2017
Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness
artículo científico publicado en 2019
Phenotypic subtypes in attention deficit hyperactivity disorder in an isolated population
artículo científico publicado en 2005
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children
artículo científico publicado en 2011
Plasma Amyloid-β Levels, Cerebral Small Vessel Disease, and Cognition: The Rotterdam Study
artículo científico publicado en 2017
Plasma amino acids and neopterin in healthy persons with Down's syndrome
scientific article published on 31 March 2007
Plasma amyloid beta, apolipoprotein E, lacunar infarcts, and white matter lesions
artículo científico publicado en 2004
Plasma beta amyloid and impaired CO2-induced cerebral vasomotor reactivity
artículo científico publicado en 2006
Plasma levels of nitric oxide related amino acids in demented subjects with Down syndrome are related to neopterin concentrations
artículo científico publicado en 2009
Plasma phosphatidylcholine and sphingomyelin concentrations are associated with depression and anxiety symptoms in a Dutch family-based lipidomics study
artículo científico publicado en 2012
Plasma β amyloid and the risk of Alzheimer's disease in Down syndrome
artículo científico publicado en 2011
Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease
artículo científico publicado en 2015
Polymorphism in the IGF-I gene: clinical relevance for short children born small for gestational age (SGA)
scientific article published on 01 June 2002
Polymorphism in the promoter region of the insulin-like growth factor I gene is related to carotid intima-media thickness and aortic pulse wave velocity in subjects with hypertension
artículo científico publicado en 2003
Polymorphisms in metabolic genes, their combination and interaction with tobacco smoke and alcohol consumption and risk of gastric cancer: a case-control study in an Italian population
artículo científico publicado en 2007
Polymorphisms in the prion protein gene and in the doppel gene increase susceptibility for Creutzfeldt-Jakob disease
artículo científico publicado en 2004
Polymorphisms in the vascular endothelial growth factor gene and risk of age-related macular degeneration: the Rotterdam Study
artículo científico publicado en 2008
Polymorphisms of the renin-angiotensin system are associated with blood pressure, atherosclerosis and cerebral white matter pathology
artículo científico publicado en 2007
Population-specific genotype imputations using minimac or IMPUTE2.
artículo científico publicado en 2015
PredictABEL: an R package for the assessment of risk prediction models
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artículo científico publicado el 24 de marzo de 2011
Predicting human height by Victorian and genomic methods
artículo científico publicado en 2009
Predicting stroke through genetic risk functions: the CHARGE Risk Score Project
artículo científico publicado en 2014
Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study
artículo científico publicado en 2008
Prediction of age-related macular degeneration in the general population: the Three Continent AMD Consortium
artículo científico publicado en 2013
Prediction of male-pattern baldness from genotypes
artículo científico publicado en 2015
Predictive testing for complex diseases using multiple genes: fact or fiction?
artículo científico publicado en 2006
Predominance of hospital deliveries among children with acute lymphocytic leukemia: speculations about neonatal exposure to fluorescent light
scientific article published on 01 July 1992
Prenatal exposure to the 1944-45 Dutch 'hunger winter' and addiction later in life
artículo científico publicado en 2008
Preparing for presymptomatic DNA testing for early onset Alzheimer's disease/cerebral haemorrhage and hereditary Pick disease
artículo científico publicado en 1997
Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala-->Gly mutation
artículo científico publicado en 1998
Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene
artículo científico publicado en 1992
Prevalence and heritability of the metabolic syndrome and its individual components in a Dutch isolate: the Erasmus Rucphen Family study
artículo científico publicado en 2008
Prevalence of refractive error in Europe: the European Eye Epidemiology (E(3)) Consortium
artículo científico publicado en 2015
Prion protein codon 129 polymorphism in mild cognitive impairment and dementia: the Rotterdam Study
scientific article published on 20 March 2020
ProbABEL package for genome-wide association analysis of imputed data
artículo científico publicado en 2010
Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease
artículo científico publicado en 2006
Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease.
artículo científico publicado en 2011
Prospects of genetic epidemiology in the 21st century
artículo científico publicado en 2003
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
article
Psychiatric history and related exposures as risk factors for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group
artículo científico publicado en 1991
Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
scholarly article published in Nature Genetics
Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
erratum
Publisher Correction: Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability
artículo científico publicado en 2019
Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
artículo científico publicado en 2019
Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project
article
Quantifying prion disease penetrance using large population control cohorts
artículo científico publicado en 2016
Rapid variance components-based method for whole-genome association analysis
artículo científico publicado en 2012
Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk
artículo científico publicado en 2015
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease
artículo científico publicado en 2016
Rare and low-frequency coding variants alter human adult height
artículo científico publicado en 2017
Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease
Rare variants in γ-aminobutyric acid type A receptor genes in rolandic epilepsy and related syndromes
artículo científico publicado en 2015
Rate of progression of Alzheimer's disease is associated with genetic risk
artículo científico publicado en 1995
Re: "Case-control studies of environmental influences in diseases with genetic determinants, with an application to Alzheimer's disease"
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artículo científico publicado el 1 de junio de 1992
Reasons for non-response in observational pharmacogenetic research
artículo científico publicado en 2009
Reducing the Genetic Risk of Age-Related Macular Degeneration With Dietary Antioxidants, Zinc, and ω-3 Fatty Acids
scientific article published on 01 June 2011
Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs
artículo científico publicado en 2016
Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes
article
Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions
artículo científico publicado en 2012
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
artículo científico publicado en 2018
Region-based association analysis of human quantitative traits in related individuals
artículo científico publicado en 2013
Relation between nicotine intake and Alzheimer's disease
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artículo científico publicado el 22 de junio de 1991
Relation between smoking and risk of dementia and Alzheimer disease: The Rotterdam Study
scholarly article by C. Reitz et al published 4 September 2007 in Neurology
Relationship between gut microbiota and circulating metabolites in population-based cohorts
scientific article published on 20 December 2019
Relationship of the Ubiquilin 1 gene with Alzheimer's and Parkinson's disease and cognitive function
artículo científico publicado en 2007
Renin-angiotensin system inhibitors, angiotensin I-converting enzyme gene insertion/deletion polymorphism, and cancer: the Rotterdam Study
scientific article published on 01 February 2008
Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease
artículo científico publicado en 2009
Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis
artículo científico publicado en 2009
Reply to Stephan et al.
artículo científico publicado en 2008
Reply to “Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis”
Reproductive period and risk of dementia in postmenopausal women
artículo científico publicado en 2001
Retinal vessel diameters and risk of impaired fasting glucose or diabetes: the Rotterdam study
artículo científico publicado en 2006
Revisiting the Role of Insulin-Like Growth Factor-I Receptor Stimulating Activity and the Apolipoprotein E in Alzheimer's Disease
scholarly article by Sara A Galle et al published 2019 in Frontiers in Aging Neuroscience
Revisiting the clinical validity of multiplex genetic testing in complex diseases
artículo científico publicado en 2004
Risk Factors for Alzheimer's Disease: The EURODEM Collaborative Re-Analysis of Case-Control Studies
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artículo científico publicado el 1 de enero de 1992
Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study
artículo científico publicado en 1998
Risk factors for Alzheimer's disease: overview of the EURODEM collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group
scientific article published on 01 January 1991
Risk factors for Creutzfeldt-Jakob disease: a reanalysis of case-control studies
artículo científico publicado en 1996
Risk factors for childhood acute non-lymphocytic leukemia: an association with maternal alcohol consumption during pregnancy?
artículo científico publicado en 1994
Risk genes associated with pediatric-onset MS but not with monophasic acquired CNS demyelination.
artículo científico publicado en 2013
Risk of left ventricular dysfunction in patients with probable Alzheimer's disease with APOE*4 allele.
artículo científico publicado en 1998
Risk scores of common genetic variants for lipid levels influence atherosclerosis and incident coronary heart disease
artículo científico publicado en 2013
Roaming through methodology. XXXVII. Unintentional population stratification in genetic case-control studies
artículo científico publicado en 2002
Role of APOE in dementia: A critical reappraisal
artículo científico publicado en 1998
Role of shared genetic and environmental factors in symptoms of depression and body composition
article
Runs of homozygosity do not influence survival to old age.
artículo científico publicado en 2011
SIRT1 genetic variation and mortality in type 2 diabetes: interaction with smoking and dietary niacin
artículo científico publicado en 2009
SIRT1 genetic variation is related to BMI and risk of obesity
artículo científico publicado en 2009
STROBE-ME too!
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artículo científico publicado el 1 de octubre de 2011
STrengthening the REporting of Genetic Association Studies (STREGA)-an extension of the STROBE statement
article
STrengthening the REporting of Genetic Association Studies (STREGA): An Extension of the STROBE Statement
article
STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement
artículo científico publicado en 2009
STrengthening the REporting of Genetic Association studies (STREGA)--an extension of the STROBE statement
scientific article published on April 2009
STrengthening the REporting of Genetic Association studies (STREGA)—an extension of the STROBE statement
article
Scientific reporting is suboptimal for aspects that characterize genetic risk prediction studies: a review of published articles based on the Genetic RIsk Prediction Studies statement
artículo científico
Score statistic to test for genetic correlation for proband-family design
artículo científico publicado en 2005
Search for Early Pancreatic Cancer Blood Biomarkers in Five European Prospective Population Biobanks Using Metabolomics
artículo científico publicado en 2019
Second probable case of vCJD in the Netherlands
artículo científico publicado en 2006
Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms
artículo científico publicado en 2009
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior
artículo científico publicado en 2010
Sequencing of high-complexity DNA pools for identification of nucleotide and structural variants in regions associated with complex traits
artículo científico publicado en 2011
Serum MHPG strongly predicts conversion to Alzheimer's disease in behaviorally characterized subjects with Down syndrome.
artículo científico publicado en 2015
Serum NGAL is Associated with Distinct Plasma Amyloid-β Peptides According to the Clinical Diagnosis of Dementia in Down Syndrome
artículo científico publicado en 2015
Serum apolipoprotein E is associated with long-term risk of Alzheimer's disease: The Rotterdam Study
artículo científico publicado en 2016
Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study
artículo científico publicado en 1998
Serum levels of interleukin-6 are not elevated in patients with Alzheimer's disease
artículo científico publicado en 1990
Seven new loci associated with age-related macular degeneration
artículo científico publicado en 2013
Sex-specific genetic effects influence variation in body composition
article
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
artículo científico publicado en 2013
Shared constitutional risks for maternal vascular-related pregnancy complications and future cardiovascular disease
artículo científico publicado en 2008
Shared genetic factors in migraine and depression: evidence from a genetic isolate
artículo científico publicado en 2010
Shared genetic factors in the co-occurrence of symptoms of depression and cardiovascular risk factors
artículo científico publicado en 2009
Short telomere length is associated with impaired cognitive performance in European ancestry cohorts.
artículo científico publicado en 2017
Single nucleotide polymorphisms in genes that are associated with a modified response to statin therapy: the Rotterdam Study
artículo científico publicado en 2010
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
artículo científico publicado en 2009
Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study
artículo científico publicado en 1998
Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose
artículo científico publicado en 2020
Smoking-dependent effects of the angiotensin-converting enzyme gene insertion/deletion polymorphism on blood pressure
artículo científico publicado en 2004
Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies
artículo científico publicado en 2016
Source of variant Creutzfeldt-Jakob disease outside United Kingdom
artículo científico publicado en 2007
Space-time clustering patterns of gliomas in The Netherlands suggest an infectious aetiology
artículo científico publicado en 2005
Standard process-oriented workflow introduces pre-analytical error when used in large study sample batches
artículo científico publicado en 2018
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases
artículo científico publicado en 2012
Strengthening the Reporting of Genetic Risk Prediction Studies: The GRIPS Statement
artículo científico publicado en 2011
Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration
artículo científico publicado en 2011
Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement
artículo científico publicado en 2011
Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement
artículo científico publicado en 2011
Strengthening the reporting of Genetic Risk Prediction Studies: The GRIPS statement
artículo científico publicado en 2011
Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement
article
Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement
article
Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement
artículo científico publicado en 2009
Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.
artículo científico publicado en 2011
Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration
artículo científico publicado en 2011
Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration
Strengthening the reporting of genetic risk prediction studies: The GRIPS Statement
artículo científico publicado en 2011
Strengthening the reporting of genetic risk prediction studies: the GRIPS statement
artículo científico publicado en 2011
Strengthening the reporting of genetic risk prediction studies: the GRIPS statement
Strengthening the reporting of genetic risk prediction studies: the GRIPS statement
Strengthening the reporting of genetic risk prediction studies: the GRIPS statement
artículo científico publicado en 2011
Strengthening the reporting of genetic risk prediction studies: the GRIPS statement.
artículo científico publicado en 2011
Strong linkage on 2q33.3 to familial early-onset generalized osteoarthritis and a consideration of two positional candidate genes
artículo científico publicado en 2006
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
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artículo científico publicado en 2018
Suggestive linkage of ADHD to chromosome 18q22 in a young genetically isolated Dutch population
artículo científico publicado en 2009
Suggestive linkage to chromosome 19 in a large Cuban family with late-onset Parkinson's disease
artículo científico publicado en 2003
Survival in elderly persons with Down syndrome
artículo científico publicado en 2008
Susceptibility loci for intracranial aneurysm in European and Japanese populations
artículo científico publicado en 2008
Susceptibility to chronic mucus hypersecretion, a genome wide association study
artículo científico publicado en 2014
TGF-β1 Polymorphisms and Risk of Myocardial Infarction and Stroke
THE ASSOCIATION BETWEEN INSULIN-LIKE GROWTH FACTOR I BIOACTIVITY, PHYSICAL ACTIVITY AND DEMENTIA
scholarly article published 1 November 2018
TMEM106B influences volume of left-sided temporal lobe and interhemispheric structures in the general population
article by Hieab H.H. Adams et al published 15 September 2014 in Biological Psychiatry
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
artículo científico publicado en 2019
Tau negative frontal lobe dementia at 17q21: significant finemapping of the candidate region to a 4.8 cM interval
artículo científico publicado en 2002
Telomere length in circulating leukocytes is associated with lung function and disease.
artículo científico publicado en 2013
The -1997 G/T and Sp1 polymorphisms in the collagen type I alpha1 (COLIA1) gene in relation to changes in femoral neck bone mineral density and the risk of fracture in the elderly: the Rotterdam study
artículo científico publicado en 2007
The -514 C->T hepatic lipase promoter region polymorphism and plasma lipids: a meta-analysis
artículo científico publicado en 2004
The -Adducin Gene Is Associated With Macrovascular Complications and Mortality in Patients With Type 2 Diabetes
article
The ACE insertion/deletion polymorphism and risk of cancer, a review and meta-analysis of the literature
artículo científico publicado en 2011
The Alzheimer's Disease Sequencing Project: Study design and sample selection
artículo científico publicado en 2017
The Association Between H63D Mutations in HFE and Amyotrophic Lateral Sclerosis in a Dutch Population
article
The Consortium on Health and Ageing: Network of Cohorts in Europe and the United States (CHANCES) project--design, population and data harmonization of a large-scale, international study
artículo científico publicado en 2014
The ERCC6 gene and age-related macular degeneration
artículo científico publicado en 2010
The Effect of Genetic Drift in a Young Genetically Isolated Population
The Effect of Genetic Drift in a Young Genetically Isolated Population
The Epistasis Project: A Multi-Cohort Study of the Effects of BDNF, DBH, and SORT1 Epistasis on Alzheimer's Disease Risk
scientific article published on 01 January 2019
The GAB2 gene and the risk of Alzheimer's disease: replication and meta-analysis
artículo científico publicado en 2008
The GenABEL Project for statistical genomics
artículo científico publicado en 2016
The Generation R Study: Biobank update 2015.
artículo científico publicado en 2014
The Generation R Study: design and cohort update 2012.
artículo científico publicado en 2012
The Generation R Study: design and cohort update 2017
artículo científico publicado en 2017
The Generation R Study: design and cohort update until the age of 4 years
article
The Genome of the Netherlands: design, and project goals
artículo científico publicado en 2014
The Glu318Gly substitution in presenilin 1 is not causally related to Alzheimer disease
artículo científico publicado en 1999
The H63D variant in the HFE gene predisposes to arthralgia, chondrocalcinosis and osteoarthritis
artículo científico publicado en 2007
The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans
article
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
artículo científico publicado en 2015
The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility
scholarly article published 13 July 2017
The PCLO gene and depressive disorders: replication in a population-based study
article
The Rotterdam Study: 2010 objectives and design update
artículo científico publicado en 2009
The Rotterdam Study: 2012 objectives and design update
artículo científico publicado en 2011
The Rotterdam Study: 2014 objectives and design update
artículo científico publicado en 2013
The Rotterdam Study: 2016 objectives and design update
artículo científico publicado en 2015
The Rotterdam Study: 2018 update on objectives, design and main results
artículo científico publicado en 2017
The Rotterdam Study: objectives and design update
artículo científico publicado en 2007
The TNFRSF6 gene is not implicated in familial early-onset Alzheimer's disease
artículo científico publicado en 2001
The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer's disease with onset before 70 years
artículo científico publicado en 2005
The Well-Known Gene HHIP and Novel Gene MECR Are Implicated in Small Airway Obstruction
artículo científico publicado en 2016
The apolipoprotein E epsilon 2 allele is associated with an increased risk of early-onset Alzheimer's disease and a reduced survival.
artículo científico publicado en 1995
The apolipoprotein E epsilon 4 allele does not influence the clinical expression of the amyloid precursor protein gene codon 693 or 692 mutations
artículo científico publicado en 1994
The apolipoprotein E gene and its age-specific effects on cognitive function
artículo científico publicado en 2008
The association between angiotensin-converting enzyme gene polymorphism and coronary calcification. The Rotterdam Coronary Calcification Study
artículo científico publicado en 2005
The association between antihypertensive drugs and glioma
artículo científico publicado en 2006
The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels
artículo científico publicado en 2014
The cholesteryl ester transfer protein (CETP) gene and the risk of Alzheimer's disease
artículo científico publicado en 2007
The cholesteryl ester transfer protein I405V polymorphism is associated with increased high-density lipoprotein levels and decreased risk of myocardial infarction: the Rotterdam Study
artículo científico publicado en 2007
The complement component 5 gene and age-related macular degeneration
artículo científico publicado en 2009
The dopamine D4 receptor gene 48-base-pair-repeat polymorphism and mood disorders: a meta-analysis
artículo científico publicado en 2005
The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project
artículo científico publicado en 2010
The dystrophin gene and cognitive function in the general population
artículo científico publicado en 2014
The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study
artículo científico publicado en 2018
The effect of APOE on dementia is not through atherosclerosis: the Rotterdam Study
scientific article published on 01 October 1999
The effect of catechol-O-methyltransferase Met/Val functional polymorphism on smoking cessation: retrospective and prospective analyses in a cohort study
artículo científico publicado en 2009
The effectiveness of HMG-CoA reductase inhibitors in an elderly population is independent of apolipoprotein E-genotypes.
artículo científico publicado en 2002
The effectiveness of hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins) in the elderly is not influenced by apolipoprotein E genotype
artículo científico publicado en 2002
The expression of type III hyperlipoproteinemia: involvement of lipolysis genes
artículo científico publicado en 2008
The first case of variant Creutzfeldt-Jakob disease in The Netherlands
artículo científico publicado en 2007
The first patient with the new variant of Creutzfeldt-Jakob's disease in The Netherlands
artículo científico publicado en 2005
The first two patients with dura mater associated Creutzfeldt-Jakob disease in the Netherlands
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artículo científico publicado el 1 de octubre de 2001
The gene encoding nicastrin, a major gamma-secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample
artículo científico publicado en 2002
The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data
artículo científico publicado en 2011
The genetic epidemiology of glioma
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artículo científico publicado el 27 de noviembre de 2001
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
artículo científico publicado en 2016
The hemochromatosis N144H mutation of SLC11A3 gene in patients with type 2 diabetes
artículo científico publicado en 2002
The impact of APOE on myocardial infarction, stroke, and dementia: the Rotterdam Study
artículo científico publicado en 2004
The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases
artículo científico publicado en 2007
The impact of low-frequency and rare variants on lipid levels
artículo científico publicado en 2015
The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study
artículo científico publicado en 2004
The influence of the alpha-adducin G460W polymorphism and angiotensinogen M235T polymorphism on antihypertensive medication and blood pressure
scientific article published on 17 May 2006
The interleukin-6-174 G/C promoter polymorphism and arterial stiffness; the Rotterdam Study
artículo científico publicado en 2008
The involvement of upstream stimulatory factor 1 in Dutch patients with familial combined hyperlipidemia
artículo científico publicado en 2006
The molecular genetic architecture of self-employment
artículo científico publicado en 2013
The neuronal transporter gene SLC6A15 confers risk to major depression
artículo científico publicado en 2011
The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders
artículo científico publicado en 2017
The rationale and design of the PERindopril GENEtic association study (PERGENE): a pharmacogenetic analysis of angiotensin-converting enzyme inhibitor therapy in patients with stable coronary artery disease
artículo científico publicado en 2008
The relationship between fertility and lifespan in humans
artículo científico publicado en 2011
The risk of bleeding complications in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon
artículo científico publicado en 2004
The risk of myocardial infarction in patients with reduced activity of cytochrome P450 2C9.
artículo científico publicado en 2007
The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon
artículo científico publicado en 2004
The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis
artículo científico publicado en 2013
The role of body mass index, insulin, and adiponectin in the relation between fat distribution and bone mineral density
artículo científico publicado en 2009
The role of hemochromatosis C282Y and H63D gene mutations in type 2 diabetes: findings from the Rotterdam Study and meta-analysis
artículo científico publicado en 2002
The sex-specific associations of the aromatase gene with Alzheimer's disease and its interaction with IL10 in the Epistasis Project
artículo científico publicado en 2013
The vast complexity of primary open angle glaucoma: disease genes, risks, molecular mechanisms and pathobiology
artículo científico publicado en 2013
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
artículo científico publicado en 2010
Three Genome-wide Association Studies and a Linkage Analysis Identify HERC2 as a Human Iris Color Gene
artículo científico publicado en 2008
Three VCP Mutations in Patients with Frontotemporal Dementia
artículo científico publicado en 2018
Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene
artículo científico publicado en 2008
Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis
artículo científico publicado en 2011
Towards predictive genetic testing of complex diseases
artículo científico publicado en 2006
Trans-ethnic meta-analysis of white blood cell phenotypes
artículo científico publicado en 2014
Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project
artículo científico publicado en 2010
Translational research in genomics of Alzheimer's disease: a review of current practice and future perspectives
scientific article published on January 2010
Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck
artículo científico publicado en 2016
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
artículo científico publicado en 2010
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
artículo científico publicado en 2009
Twenty loci associated with bone mineral density identified by large-scale meta-analysis of genome-wide association datasets
Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram
artículo científico publicado en 2016
Two MTHFR polymorphisms, maternal B-vitamin intake, and CHDs
artículo científico publicado en 2008
Type 2 diabetes gene TCF7L2 polymorphism is not associated with fetal and postnatal growth in two birth cohort studies
artículo científico publicado en 2009
Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics
artículo científico publicado en 2018
Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease
artículo científico publicado en 2009
Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes
artículo científico publicado en 2010
VEGF polymorphisms are associated with endocardial cushion defects: a family-based case-control study
artículo científico publicado en 2010
Value of the HLA-DRB1 shared epitope for predicting radiographic damage in rheumatoid arthritis depends on the individual patient risk profile
artículo científico publicado en 2006
Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations
artículo científico publicado en 2010
Variant Creutzfeldt-Jakob disease
scientific article published on 01 January 2003
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
artículo científico publicado en 2013
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight
artículo científico publicado en 2010
Variants in MTNR1B influence fasting glucose levels
artículo científico publicado en 2008
Variants in STAT5B Associate with Serum TC and LDL-C Levels
article published in 2011
Variants in TTC25 affect autistic trait in patients with autism spectrum disorder and general population.
artículo científico publicado en 2017
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry
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scientific article published on 13 July 2009
Variation in the IGF-1 gene is associated with lymphocyte subset counts in neonates: the Generation R Study
artículo científico publicado en 2008
Variation in the IGF1 gene and growth in foetal life and infancy. The Generation R Study
scientific article published on 19 September 2007
Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular disease
scientific article published on 12 October 2010
Variations in estrogen receptor alpha gene and risk of dementia, and brain volumes on MRI.
artículo científico publicado en 2004
WNT10A exonic variant increases the risk of keratoconus by decreasing corneal thickness
artículo científico publicado en 2015
White Matter Lesion Progression: Genome-Wide Search for Genetic Influences
artículo científico publicado en 2015
Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation
article
Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.
artículo científico publicado en 2018
Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis
article
Whole-Exome Sequencing in Age-Related Macular Degeneration Identifies Rare Variants in COL8A1, a Component of Bruch's Membrane
Whole-Genome Linkage Scan Combined With Exome Sequencing Identifies Novel Candidate Genes for Carotid Intima-Media Thickness
article
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol
artículo científico publicado en 2014
Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture
artículo científico publicado en 2015
[Gliomas: the role of environmental risk factors and genetic predisposition]
artículo científico publicado en 2005
[The role of apolipoproteins E genotyping in the differential diagnosis of dementia]
artículo científico publicado en 1996
miLD and booLD programs for calculation and analysis of corrected linkage disequilibrium
artículo científico publicado en 2003