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Lista de obras de Leif Groop

1-Hour Post-OGTT Glucose Improves the Early Prediction of Type 2 Diabetes by Clinical and Metabolic Markers

scientific article published on 01 April 2019

35th Annual Meeting of the European Association for the Study of Diabetes

artículo científico

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

5' flanking variants of resistin are associated with obesity

artículo científico publicado en 2002

A Bayesian Network analysis of the probabilistic relations between risk factors in the predisposition to type 2 diabetes

artículo científico publicado en 2015

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.

artículo científico publicado en 2018

A Genome-Wide Scan in Families With Maturity-Onset Diabetes of the Young: Evidence for Further Genetic Heterogeneity

article

A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits

artículo científico publicado en 2016

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes

artículo científico publicado en 2016

A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.

artículo científico publicado en 2017

A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-Cells

artículo científico publicado en 2016

A case report. Rosiglitazone treatment was highly effective yet had to be terminated

artículo científico publicado en 2002

A central role for GRB10 in regulation of islet function in man.

artículo científico publicado en 2014

A combination of human leukocyte antigen DQB1*02 and the tumor necrosis factor alpha promoter G308A polymorphism predisposes to an insulin-deficient phenotype in patients with type 2 diabetes

artículo científico publicado en 2003

A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals

artículo científico publicado en 2009

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

artículo científico publicado en 2009

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

artículo científico publicado en 2011

A common variant in the MTNR1b gene is associated with increased risk of impaired fasting glucose (IFG) in youth with obesity

artículo científico publicado en 2015

A common variant near the PRL gene is associated with increased adiposity in males

artículo científico publicado en 2010

A common variant upstream of the PAX6 gene influences islet function in man.

artículo científico publicado en 2011

A genome wide scan for early onset primary hypertension in Scandinavians

artículo científico publicado en 2003

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

artículo científico publicado en 2012

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes

article

A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes.

artículo científico publicado en 2011

A male-specific quantitative trait locus on 1p21 controlling human stature

artículo científico publicado en 2005

A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes

artículo científico publicado en 2003

A multigenerational study on phenotypic consequences of the most common causal variant of HNF1A-MODY

artículo científico publicado en 2021

A non-synonymous variant in SLC30A8 is not associated with type 1 diabetes in the Danish population

artículo científico publicado en 2008

A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging

artículo científico publicado en 2015

A novel mechanism of glipizide sulfonylurea action: decreased metabolic clearance rate of insulin

scientific article published on 01 December 1995

A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

article

A novel test for recessive contributions to complex diseases implicates Bardet-Biedl syndrome gene BBS10 in idiopathic type 2 diabetes and obesity

artículo científico publicado en 2014

A polymorphism in the adiponectin gene influences adiponectin expression levels in visceral fat in obese subjects

artículo científico publicado en 2006

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

A prospective study of clinical and metabolic associates of proteinuria in patients with type 2 diabetes mellitus

artículo científico publicado en 1993

A recurring dominant negative mutation causes autosomal dominant growth hormone deficiency--a clinical research center study

artículo científico publicado en 1995

A reference panel of 64,976 haplotypes for genotype imputation

artículo científico publicado en 2016

A single nucleotide polymorphism associates with the response of muscle ATP synthesis to long-term exercise training in relatives of type 2 diabetic humans

artículo científico publicado en 2011

A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue

artículo científico publicado en 2013

A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets

artículo científico publicado en 2012

A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion

artículo científico publicado en 2009

A variant in the transcription factor 7-like 2 (TCF7L2) gene is associated with an increased risk of gestational diabetes mellitus

artículo científico publicado en 2007

Absence of Islet Autoantibodies and Modestly Raised Glucose Values at Diabetes Diagnosis Should Lead to Testing for MODY: Lessons From a 5-Year Pediatric Swedish National Cohort Study

scientific article published on 08 November 2019

Activation of imidazoline receptor I2, and improved pancreatic β-cell function in human islets

scientific article published on 26 June 2018

Adhesion G Protein-Coupled Receptor G1 (ADGRG1/GPR56) and Pancreatic β-Cell Function

artículo científico publicado en 2016

Adult-onset type 1 diabetic patients with less severe clinical manifestation have less risk DR-DQ genotypes than childhood-onset patients

artículo científico publicado en 2020

Age at menopause, reproductive life span, and type 2 diabetes risk: results from the EPIC-InterAct study

artículo científico publicado en 2012

Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle

article

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

artículo científico publicado en 2015

Age-related clonal hematopoiesis associated with adverse outcomes

artículo científico publicado en 2014

Alcohol and the risk for latent autoimmune diabetes in adults: results based on Swedish ESTRID study

artículo científico publicado en 2014

Amylin in adult-onset diabetes--cause or consequence?

artículo científico publicado el 1 de enero de 1990

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

artículo científico publicado en 2017

An empirical index of insulin sensitivity from short IVGTT: validation against the minimal model and glucose clamp indices in patients with different clinical characteristics

artículo científico publicado en 2009

An investigation of serum concentration of apoM as a potential MODY3 marker using a novel ELISA.

artículo científico publicado en 2009

Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases.

artículo científico publicado en 2016

Analysis of TBC1D4 in patients with severe insulin resistance.

artículo científico publicado en 2010

Analysis of case-control association studies with known risk variants

artículo científico publicado en 2012

Aortic diameter at age 65 in men with newly diagnosed type 2 diabetes

artículo científico publicado en 2017

Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults

artículo científico publicado en 2009

Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes

artículo científico publicado en 2013

Assessment of exercise capacity in women with type 2 diabetes

scientific article published on 27 May 2008

Association between LTA, TNF and AGER polymorphisms and late diabetic complications

artículo científico publicado en 2008

Association between a polymorphism in the carboxyl ester lipase gene and serum cholesterol profile

artículo científico publicado en 2004

Association between a variant in the 11 beta-hydroxysteroid dehydrogenase type 2 gene and primary hypertension

scientific article published on 01 December 2000

Association between depressive symptoms and metabolic syndrome is not explained by antidepressant medication: results from the PPP-Botnia Study

artículo científico publicado en 2011

Association between genetic risk variants and glucose intolerance during pregnancy in north Indian women

Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies

artículo científico publicado en 2011

Association of BTG2, CYR61, ZFP36, and SCD gene polymorphisms with Graves' disease and ophthalmopathy

artículo científico publicado en 2014

Association of IRS1 genetic variants with glucose control and insulin resistance in type 2 diabetic patients from Bosnia and Herzegovina

scientific article published on 19 March 2019

Association of common variation in the HNF1alpha gene region with risk of type 2 diabetes

scientific article published on 01 August 2005

Association of microsatellite polymorphisms of the human 14q13.2 region with type 2 diabetes mellitus in Latvian and Finnish populations

artículo científico publicado en 2007

Association of the E23K polymorphism in the KCNJ11 gene with gestational diabetes mellitus

scientific article published on 17 November 2005

Association of the calpain-10 gene with type 2 diabetes in Europeans: Results of pooled and meta-analyses

article

Association of variants in HLA-DQA1-DQB1, PTPN22, INS, and CTLA4 with GAD autoantibodies and insulin secretion in nondiabetic adults of the Botnia Prospective Study

Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes

artículo científico publicado en 2004

Association testing of common variants in the insulin receptor substrate-1 gene (IRS1) with type 2 diabetes

article

Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people

artículo científico publicado en 2005

Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people

artículo científico publicado en 2005

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of dietary fiber with glucose metabolism in nondiabetic relatives of subjects with type 2 diabetes: the Botnia Dietary Study

artículo científico publicado en 2003

Atrial Natriuretic Peptide in the High Normal Range Is Associated With Lower Prevalence of Insulin Resistance.

artículo científico publicado en 2016

Authors' Reply

article published 28 February 2006

Autoimmunity to CD38 and GAD in Type I and Type II diabetes: CD38 and HLA genotypes and clinical phenotypes

article by A. Antonelli et al published 24 July 2002 in Diabetologia

Bariatric Surgery Enhances Splanchnic Vascular Responses in Patients With Type 2 Diabetes

artículo científico publicado en 2017

Beta(2)-adrenergic receptor gene variation and hypertension in subjects with type 2 diabetes

artículo científico publicado en 2001

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Biomarkers of rapid chronic kidney disease progression in type 2 diabetes

artículo científico publicado en 2015

Bivariate Genome-Wide Association Study of Depressive Symptoms with Type 2 Diabetes and Quantitative Glycemic Traits

artículo científico publicado en 2017

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

artículo científico publicado en 2016

Brain natriuretic peptide is related to diastolic dysfunction whereas urinary albumin excretion rate is related to left ventricular mass in asymptomatic type 2 diabetes patients

artículo científico publicado en 2010

Branched-chain amino acids are associated with odd-chain fatty acids in normoglycaemic individuals.

artículo científico publicado en 2017

Bringing diabetes therapeutics to the big screen

artículo científico publicado en 2003

C-peptide and free insulin determinations in type I diabetes; relationships with metabolic control and insulin therapy.

artículo científico publicado en 1984

CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion

artículo científico publicado en 2016

CCAAT/enhancer binding protein alpha (C/EBPalpha) in adipose tissue regulates genes in lipid and glucose metabolism and a genetic variation in C/EBPalpha is associated with serum levels of triglycerides

artículo científico publicado en 2008

COX-2 and SCD, markers of inflammation and adipogenesis, are related to disease activity in Graves' ophthalmopathy

artículo científico publicado en 2007

Calpain 10 and type 2 diabetes: are we getting closer to an explanation?

artículo científico publicado en 2005

Calpain-10 expression is elevated in pancreatic islets from patients with type 2 diabetes

artículo científico publicado en 2009

Can complement factors 5 and 8 and transthyretin be used as biomarkers for MODY 1 (HNF4A-MODY) and MODY 3 (HNF1A-MODY)?

scientific article published on 01 July 2008

Can diabetic nephropathy be prevented?

artículo científico publicado el 1 de enero de 1990

Can genetics improve precision of therapy in diabetes?

artículo científico publicado en 2014

Candidate genes for type 2 diabetes

artículo científico publicado en 2004

Cardiovascular morbidity and mortality associated with the metabolic syndrome

artículo científico publicado en 2001

Carl-David Agardh, 1946-2013.

artículo científico publicado en 2014

Changes of lipolytic enzymes cluster with insulin resistance syndrome. Botnia Study Group

artículo científico publicado en 1995

Characteristics of non-insulin-dependent diabetic patients with secondary failure to oral antidiabetic therapy.

artículo científico publicado en 1989

Characterization of Patients with Chlorpropamide-Alcohol Flush

artículo científico publicado el 1 de enero de 1984

Characterization of a naturally occurring mutation (L107I) in the HNF1 alpha (MODY3) gene

artículo científico publicado en 2002

Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect

scientific article published on February 1997

Characterization of the Prediabetic State

artículo científico publicado el 1 de septiembre de 1997

Characterization of the human skeletal muscle glycogen synthase gene (GYS1) promoter

artículo científico publicado en 2004

Chlorpropamide-alcohol flush: significance of body weight, sex and serum chlorpropamide level

artículo científico publicado en 1984

Chromosome X-wide association study identifies Loci for fasting insulin and height and evidence for incomplete dosage compensation

artículo científico publicado en 2014

Chronic complications in patients with slowly progressing autoimmune type 1 diabetes (LADA).

artículo científico publicado en 1999

Chronic diabetic complications in patients with MODY3 diabetes

artículo científico publicado en 1998

Classifying diabetes according to the new WHO clinical stages

scientific article published on 01 January 2001

Clinical and metabolic characteristics of type 1 and type 2 diabetes: an epidemiological study from the Närpes community in western Finland

artículo científico publicado el 1 de agosto de 1992

Clinical risk factors, DNA variants, and the development of type 2 diabetes

artículo científico publicado en 2008

Clusters provide a better holistic view of type 2 diabetes than simple clinical features

artículo científico publicado en 2019

Co-occurrence of risk alleles in or near genes modulating insulin secretion predisposes obese youth to prediabetes

artículo científico publicado en 2013

Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time

artículo científico publicado en 2011

Coffee consumption and the risk of latent autoimmune diabetes in adults--results from a Swedish case-control study

artículo científico publicado en 2014

Coffee consumption, genetic susceptibility and risk of latent autoimmune diabetes in adults: A population-based case-control study

artículo científico publicado en 2018

Combination of insulin and glibenclamide in the treatment of elderly non-insulin dependent (type 2) diabetic patients.

artículo científico publicado en 1985

Common Variants in the ENPP1 Gene Are Not Reproducibly Associated With Diabetes or Obesity

article

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity

artículo científico publicado en 2014

Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits

artículo científico publicado en 2010

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

artículo científico publicado en 2008

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

artículo científico publicado en 2008

Common variant in the HMGA2 gene increases susceptibility to nephropathy in patients with type 2 diabetes

artículo científico publicado en 2012

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

artículo científico publicado en 2010

Common variants at 30 loci contribute to polygenic dyslipidemia

artículo científico publicado en 2009

Common variants in HNF-1 alpha and risk of type 2 diabetes

artículo científico publicado en 2006

Common variants in MODY genes increase the risk of gestational diabetes mellitus

artículo científico publicado en 2006

Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes

artículo científico publicado en 2008

Common variants near MC4R are associated with fat mass, weight and risk of obesity

artículo científico publicado en 2008

Comparing strategies to fine-map the association of common SNPs at chromosome 9p21 with type 2 diabetes and myocardial infarction

artículo científico publicado en 2011

Comparison of pharmacokinetics, metabolic effects and mechanisms of action of glyburide and glipizide during long-term treatment

artículo científico publicado en 1987

Complex Relationship Between Blood Pressure and Mortality in Type 2 Diabetic Patients

Comprehensive association testing of common mitochondrial DNA variation in metabolic disease

artículo científico publicado en 2006

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

artículo científico publicado en 2008

Consequences of a family history of type 1 and type 2 diabetes on the phenotype of patients with type 2 diabetes

artículo científico publicado en 2000

Consumption of red meat, genetic susceptibility, and risk of LADA and type 2 diabetes

scientific article published on 22 May 2020

Contribution of Known and Unknown Susceptibility Genes to Early-Onset Diabetes in Scandinavia: Evidence for Heterogeneity

article

Contribution of insulin-stimulated glucose uptake and basal hepatic insulin sensitivity to surrogate measures of insulin sensitivity

artículo científico publicado en 2004

Contribution of muscle and liver to glucose-fatty acid cycle in humans

artículo científico publicado en 1993

Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.

artículo científico publicado en 2018

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Cosegregation of MIDD and MODY in a pedigree: functional and clinical consequences

artículo científico publicado en 2004

Country of birth modifies the association of fatty liver index with insulin action in Middle Eastern immigrants to Sweden

artículo científico publicado en 2015

DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk

artículo científico publicado en 2016

DOLORisk: study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain

artículo científico publicado en 2018

Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistance

artículo científico publicado en 2002

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Demonstrating stratification in a European American population

Demonstration of a novel feedback mechanism between FFA oxidation from intracellular and intravascular sources

artículo científico publicado en 1991

Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent manner

artículo científico publicado en 2010

Depressive symptoms, antidepressant medication use, and insulin resistance: the PPP-Botnia Study

artículo científico publicado en 2011

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study

artículo científico publicado en 2011

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

artículo científico publicado en 2010

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Determinants of postabsorptive endogenous glucose output in non-diabetic subjects. European Group for the Study of Insulin Resistance (EGIR).

artículo científico publicado en 2000

Development and Validation of a Path Length Calculation for Carotid-Femoral Pulse Wave Velocity Measurement: A TASCFORCE, SUMMIT, and Caerphilly Collaborative Venture.

artículo científico publicado en 2018

Development of new peripheral arterial occlusive disease in patients with type 2 diabetes during a mean follow-up of 11 years

artículo científico publicado en 2003

Diabetes genetics. A seventh sense for the successful sequel of 'come together'. "The genotypes and phenotypes of diabetes". Bergen, Norway. April 22-26, 2009. 2nd meeting of 'EASD Study Group on Genetics of Diabetes' and 44th annual meeting of the

artículo científico publicado en 2009

Diabetes half-way between type 1 and type 2. LADA--the second biggest diabetic group where best treatment is uncertain

artículo científico publicado en 2008

Dietary intakes and plasma concentrations of carotenoids and tocopherols in relation to glucose metabolism in subjects at high risk of type 2 diabetes: the Botnia Dietary Study

artículo científico publicado en 2003

Differences in HLA types in children with insulin-dependent diabetes diagnosed in 1960s, 1970s, and 1980s

artículo científico publicado en 1988

Differences in associations between HSD11B1 gene expression and metabolic parameters in subjects with and without impaired glucose homeostasis

artículo científico publicado en 2010

Differences in effects of insulin glargine or pioglitazone added to oral anti-diabetic therapy in patients with type 2 diabetes: what to add--insulin glargine or pioglitazone?

artículo científico publicado en 2008

Different acute and chronic effects of acipimox treatment on glucose and lipid metabolism in patients with type 2 diabetes

artículo científico publicado en 1993

Different effects of glyburide and glipizide on insulin secretion and hepatic glucose production in normal and NIDDM subjects

artículo científico publicado en 1987

Different effects of insulin and oral antidiabetic agents on glucose and energy metabolism in type 2 (non-insulin-dependent) diabetes mellitus

artículo científico publicado en 1989

Differential gene expression in adipose tissue from obese human subjects during weight loss and weight maintenance

artículo científico publicado en 2012

Differential phosphorylation of Janus kinase 2, Stat5A and Stat5B in response to growth hormone in primary rat adipocytes

artículo científico publicado en 2001

Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis.

artículo científico publicado en 2016

Dipping and variability of blood pressure and heart rate at night are heritable traits.

artículo científico publicado en 2005

Discerning the ancestry of European Americans in genetic association studies

artículo científico publicado en 2007

Discovering human diabetes-risk gene function with genetics and physiological assays

artículo científico publicado en 2018

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

artículo científico publicado en 2015

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Distribution and medical impact of loss-of-function variants in the Finnish founder population

artículo científico publicado en 2014

Diurnal pattern of plasma insulin and blood glucose during glibenclamide and glipizide therapy in elderly diabetics

scientific article published on 01 January 1980

Down-regulation of insulin receptor substrates (IRS)-1 and IRS-2 and Src homologous and collagen-like protein Shc gene expression by insulin in skeletal muscle is not associated with insulin resistance or type 2 diabetes

artículo científico publicado en 2002

Downregulation of type II diabetes mellitus and maturity onset diabetes of young pathways in human pancreatic islets from hyperglycemic donors.

artículo científico publicado en 2014

Drug therapy in adult-onset diabetes

artículo científico publicado el 1 de enero de 1990

EPMA-World Congress 2015

artículo científico publicado en 2016

Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

artículo científico publicado en 1989

Early metabolic markers identify potential targets for the prevention of type 2 diabetes

artículo científico

Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance

artículo científico publicado en 2013

Education, immigration and income as risk factors for hemoglobin A1c >70 mmol/mol when diagnosed with type 2 diabetes or latent autoimmune diabetes in adult: a population-based cohort study

artículo científico publicado en 2017

Effect of a common variant of the PCSK2 gene on reduced insulin secretion

artículo científico publicado en 2012

Effect of beta-blocking drugs on beta-cell function and insulin sensitivity in hypertensive non-diabetic patients

artículo científico publicado el 1 de enero de 1984

Effect of gender on insulin resistance associated with aging

artículo científico publicado el 1 de octubre de 1992

Effect of glyburide on glycemic control, insulin requirement, and glucose metabolism in insulin-treated diabetic patients

artículo científico publicado en 1987

Effect of pioglitazone versus insulin glargine on cardiac size, function, and measures of fluid retention in patients with type 2 diabetes

artículo científico publicado en 2009

Effect of salt on insulin sensitivity differs according to gender and degree of salt sensitivity.

artículo científico publicado en 2000

Effects of GIP on regional blood flow during normoglycemia and hyperglycemia in anesthetized rats.

artículo científico publicado en 2018

Effects of TCF7L2 rs7903146 variant on metformin response in patients with type 2 diabetes

artículo científico publicado en 2019

Effects of acarbose on the relationship between changes in GIP and insulin responses to meals in normal subjects

artículo científico publicado en 1986

Effects of common genetic variants associated with type 2 diabetes and glycemic traits on α- and β-cell function and insulin action in humans

artículo científico publicado en 2013

Effects of ingestion routes on hormonal and metabolic profiles in gastric-bypassed humans

artículo científico publicado en 2013

Effects of meal and incretins in the regulation of splanchnic blood flow

artículo científico publicado en 2017

Effects of the combination of insulin and glibenclamide in type 2 (non-insulin-dependent) diabetic patients with secondary failure to oral hypoglycaemic agents

artículo científico publicado en 1988

Effects of weight loss on substrate oxidation, energy expenditure, and insulin sensitivity in obese individuals

artículo científico publicado el 1 de febrero de 1992

Elevated plasma levels of Nt-proBNP in patients with type 2 diabetes without overt cardiovascular disease

artículo científico publicado en 2004

Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

artículo científico publicado en 2008

Epigenetic regulation of glucose-stimulated osteopontin (OPN) expression in diabetic kidney

artículo científico publicado en 2015

Epigenetic regulation of the thioredoxin-interacting protein (TXNIP) gene by hyperglycemia in kidney

artículo científico publicado en 2016

Epigenetics: a molecular link between environmental factors and type 2 diabetes

artículo científico publicado en 2009

Erratum to "Prevalence and risk factors for diabetic retinopathy at diagnosis (DRAD) in patients recently diagnosed with type 2 diabetes (T2D) or latent autoimmune diabetes in the adult (LADA)" [J Diabetes Complications 30(8): 1456-1461]

artículo científico publicado en 2017

Erratum to: Large-scale association study between two coding LRP5 gene polymorphisms and bone phenotypes and fractures in men.

artículo científico publicado en 2008

Erratum. Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetes 2019;68:441-456

scientific article published on 27 April 2020

Erratum: Corrigendum: Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

scholarly article published in Nature Genetics

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

Ethnic differences in the contribution of insulin action and secretion to type 2 diabetes in immigrants from the Middle East compared to native Swedes

artículo científico publicado en 2014

Ethnicity is an independent risk indicator when estimating diabetes risk with FINDRISC scores: a cross sectional study comparing immigrants from the Middle East and native Swedes

artículo científico publicado en 2014

Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes

article

Evaluation of the effects of exercise on insulin sensitivity in Arabian and Swedish women with type 2 diabetes.

artículo científico publicado en 2009

Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans

artículo científico publicado en 2007

Evidence that BMI and type 2 diabetes share only a minor fraction of genetic variance: a follow-up study of 23,585 monozygotic and dizygotic twins from the Finnish Twin Cohort Study

article

Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes

artículo científico publicado en 2016

Exercise capacity in relation to body fat distribution and muscle fibre distribution in elderly male subjects with impaired glucose tolerance, type 2 diabetes and matched controls

scientific article published on 01 June 2011

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

artículo científico publicado en 2012

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

Exome-wide association study on Albuminuria identifies a novel rare variant in CUBN and additional genes, in 33,985 Europeans with and without diabetes

article

Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity

artículo científico publicado en 2014

Expression of the transcription factor 7-like 2 gene (TCF7L2) in human adipocytes is down regulated by insulin

artículo científico publicado en 2008

Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes

artículo científico publicado en 2013

Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a 6-month exercise intervention

article

FOETAL for NCD-FOetal Exposure and Epidemiological Transitions: the role of Anaemia in early Life for Non-Communicable Diseases in later life: a prospective preconception study in rural Tanzania

artículo científico publicado en 2019

FOXC2 mRNA Expression and a 5' untranslated region polymorphism of the gene are associated with insulin resistance.

artículo científico publicado en 2002

FTO genotype is associated with phenotypic variability of body mass index

artículo científico publicado en 2012

FTO, type 2 diabetes, and weight gain throughout adult life: a meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies

artículo científico publicado en 2011

Factors associated with basal metabolic rate in patients with type 2 (non-insulin-dependent) diabetes mellitus

artículo científico publicado el 1 de octubre de 1992

Factors influencing beta-cell function and insulin sensitivity in patients with type 2 (non-insulin-dependent) diabetes

artículo científico publicado en 1984

Familiality of metabolic abnormalities is dependent on age at onset and phenotype of the type 2 diabetic proband

artículo científico publicado en 2003

Family history of diabetes and its relationship with insulin secretion and insulin sensitivity in Iraqi immigrants and native Swedes: a population-based cohort study

artículo científico publicado en 2017

Family history of type 1 and type 2 diabetes and risk of latent autoimmune diabetes in adults (LADA).

artículo científico publicado en 2017

Fasting versus postload plasma glucose concentration and the risk for future type 2 diabetes: results from the Botnia Study

artículo científico publicado en 2008

Fat feeding impairs glycogen synthase activity in mice without effects on its gene expression

artículo científico publicado en 2003

Fatty fish consumption and risk of latent autoimmune diabetes in adults

artículo científico publicado en 2014

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

artículo científico publicado en 2018

First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes

artículo científico publicado en 2018

First-Degree Relatives of Type 2 Diabetic Patients Have Reduced Expression of Genes Involved in Fatty Acid Metabolism in Skeletal Muscle

article

Fostering improved human islet research: a European perspective

scientific article published on 13 June 2019

Fuel metabolism in anorexia nervosa and simple obesity

artículo científico publicado en 1991

Functional Investigations of HNF1A Identify Rare Variants as Risk Factors for Type 2 Diabetes in the General Population

artículo científico publicado en 2016

Functional variant disrupts insulin induction of USF1: mechanism for USF1-associated dyslipidemias

scientific article published on 12 June 2009

Gastric bypass improves β-cell function and increases β-cell mass in a porcine model

artículo científico publicado en 2014

Gastric bypass in the pig increases GIP levels and decreases active GLP-1 levels

artículo científico publicado en 2017

Gene expression in Graves' ophthalmopathy and arm lymphedema: similarities and differences.

artículo científico publicado en 2011

Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study

artículo científico publicado en 2014

Genes and type 2 diabetes mellitus

scientific article published on 01 June 2008

Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC

scientific article published on 16 December 2019

Genetic Variation in the Glucose-Dependent Insulinotropic Polypeptide Receptor Modifies the Association between Carbohydrate and Fat Intake and Risk of Type 2 Diabetes in the Malmö Diet and Cancer Cohort

Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study).

artículo científico publicado en 2008

Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle

scientific article (publication date: November 2007)

Genetic and nongenetic determinants of skeletal muscle glucose transporter 4 messenger ribonucleic acid levels and insulin action in twins

artículo científico publicado en 2005

Genetic and nongenetic regulation of CAPN10 mRNA expression in skeletal muscle

artículo científico publicado en 2005

Genetic association analysis of LARS2 with type 2 diabetes

artículo científico publicado en 2010

Genetic background of the non-insulin dependent diabetes

artículo científico publicado en 1994

Genetic determinants of circulating GIP and GLP-1 concentrations.

artículo científico publicado en 2017

Genetic determinants of glucose levels in pregnancy: genetic risk scores analysis and GWAS in the Norwegian STORK cohort

Genetic determinants of glucose levels in pregnancy: genetic risk scores analysis and GWAS in the Norwegian STORK cohort

Genetic dissection of type 2 diabetes

artículo científico publicado en 2008

Genetic evidence of assortative mating in humans

article

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

artículo científico publicado en 2009

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

artículo científico publicado en 2015

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

artículo científico publicado en 2018

Genetic prediction of future type 2 diabetes

artículo científico publicado en 2005

Genetic prediction of postpartum diabetes in women with gestational diabetes mellitus

artículo científico publicado en 2012

Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes

artículo científico publicado en 2008

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic susceptibility to non-insulin dependent diabetes

artículo científico publicado en 1994

Genetic testing for maturity onset diabetes of the young: uptake, attitudes and comparison with hereditary non-polyposis colorectal cancer.

artículo científico publicado en 2005

Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D

artículo científico publicado en 2020

Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes

artículo científico publicado en 2013

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

artículo científico publicado en 2011

Genetic variants of thiazide-sensitive NaCl-cotransporter in Gitelman's syndrome and primary hypertension

scientific article published on 01 September 2000

Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins

artículo científico publicado en 2009

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs

artículo científico publicado en 2009

Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts

artículo científico publicado en 2009

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

scientific journal article

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

artículo científico publicado en 2011

Genetically determined height and coronary artery disease

artículo científico publicado en 2015

Genetics of Type 2 Diabetes: It Matters From Which Parent We Inherit the Risk

artículo científico publicado en 2015

Genetics of diabetes--are we missing the genes or the disease?

artículo científico publicado en 2013

Genetics of gestational diabetes mellitus

artículo científico publicado en 2007

Genetics of type 2 diabetes-pitfalls and possibilities

artículo científico publicado en 2015

Genetics of type 2 diabetes.

artículo científico publicado en 2010

Genetics of type 2 diabetes. An overview

artículo científico publicado en 2009

Genetics of type 2 diabetes. On overview

artículo científico publicado en 2009

Genetics of visceral obesity and insulin resistance: relationship to non-insulin-dependent diabetes mellitus

artículo científico publicado en 1998

Genome editing of human pancreatic beta cell models: problems, possibilities and outlook

scientific article published on 03 June 2019

Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin

artículo científico publicado en 2014

Genome wide meta-analysis identifies novel determinants of circulating serum progranulin

artículo científico publicado en 2017

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

artículo científico publicado en 2016

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

artículo científico publicado en 2007

Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study

artículo científico publicado en 2020

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

artículo científico publicado en 2011

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association study for type 2 diabetes: clinical applications

scientific article published on April 2009

Genome-wide association study identifies eight loci associated with blood pressure

artículo científico publicado en 2009

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

artículo científico publicado en 2011

Genome-wide association study of urinary albumin excretion rate in patients with type 1 diabetes

article by Niina Sandholm et al published 5 March 2014 in Diabetologia

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genotypes of HLA, TCF7L2, and FTO as potential modifiers of the association between sweetened beverage consumption and risk of LADA and type 2 diabetes

scientific article published on 17 January 2019

Genotypic and phenotypic differences between Arabian and Scandinavian women with gestational diabetes mellitus

artículo científico publicado en 2004

Ghrelin suppresses insulin secretion in human islets and type 2 diabetes patients have diminished islet ghrelin cell number and lower plasma ghrelin levels

artículo científico publicado en 2020

Glibenclamide and gliquidone in the treatment of non-insulin-dependent diabetes mellitus

artículo científico publicado en 1982

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

artículo científico publicado en 2014

Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA

artículo científico publicado en 2019

Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

artículo científico publicado en 2015

Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality: a prospective study

scientific article published on 23 January 2020

Glucose-induced Changes in Gene Expression in Human Pancreatic Islets - Causes or Consequences of Chronic Hyperglycemia

artículo científico publicado en 2017

Glutamic acid decarboxylase antibody positivity is associated with an impaired insulin response to glucose and arginine in nondiabetic patients with autoimmune thyroiditis

artículo científico publicado en 2002

Glycaemic and nonglycaemic effects of pioglitazone in triple oral therapy of patients with type 2 diabetes.

artículo científico publicado en 2006

Growth hormone replacement therapy induces insulin resistance by activating the glucose-fatty acid cycle

artículo científico publicado en 2003

HAPT2D: High accuracy of prediction of T2D with a model combining basic and advanced data depending on availability

artículo científico publicado en 2018

HLA-antigens and immunity to insulin in insulin-dependent diabetics with or without diabetic neuropathy

artículo científico publicado en 1988

HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets

artículo científico publicado en 2016

Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland

scholarly article by Alicia R Martin et al published 3 May 2018 in American Journal of Human Genetics

Haplotype construction of the FRDA gene and evaluation of its role in type II diabetes

artículo científico publicado en 2005

Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region

artículo científico publicado en 2004

Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB2 [corrected] with type 2 diabetes

artículo científico publicado en 2006

Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research

artículo científico publicado en 2016

Heredity for hypertension influences intra-uterine growth and the relation between fetal growth and adult blood pressure

artículo científico publicado en 1999

Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study

article by Peter Almgren et al published 9 August 2011 in Diabetologia

Heritability of ambulatory and office blood pressure phenotypes in Swedish families

artículo científico publicado en 2004

Heritability of model-derived parameters of beta cell secretion during intravenous and oral glucose tolerance tests: a study of twins

artículo científico publicado en 2005

Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis

artículo científico publicado en 2014

Heterogeneity of diabetes - An Indian perspective

scientific article published on 11 July 2018

Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance

artículo científico publicado en 2017

Heterozygous RFX6 protein truncating variants cause Maturity-Onset Diabetes of the Young (MODY) with reduced penetrance

High Prevalence of Gestational Diabetes Mellitus in Rural Tanzania-Diagnosis Mainly Based on Fasting Blood Glucose from Oral Glucose Tolerance Test

artículo científico publicado en 2020

High frequency of mutations in MODY and mitochondrial genes in Scandinavian patients with familial early-onset diabetes

article

High levels of nonesterified fatty acids are associated with increased familial risk of cardiovascular disease

artículo científico publicado en 2000

High prevalence of type 2 diabetes in Iraqi and Swedish residents in a deprived Swedish neighbourhood--a population based study

artículo científico publicado en 2011

High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people

artículo científico publicado en 2006

Histone acetylation of glucose-induced thioredoxin-interacting protein gene expression in pancreatic islets

artículo científico publicado en 2016

Home monitoring of blood glucose

artículo científico publicado el 1 de enero de 1979

Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks

artículo científico publicado en 2016

Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity

scientific journal article

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

scientific article published on 28 June 2019

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease

scientific article published on 12 March 2020

Hyperinsulinemia and insulin resistance are associated with multiple abnormalities of lipoprotein subclasses in glucose-tolerant relatives of NIDDM patients. Botnia Study Group.

artículo científico publicado en 1996

Hyperproinsulinemia of type II diabetes is not present before the development of hyperglycemia

artículo científico publicado en 1994

IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies

artículo científico publicado en 2006

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

artículo científico publicado en 2015

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

artículo científico publicado en 2015

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

artículo científico publicado en 2016

Identification of biomarkers for glycaemic deterioration in type 2 diabetes

artículo científico publicado en 2023

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia

artículo científico publicado en 2014

Identification of ten loci associated with height highlights new biological pathways in human growth

artículo científico publicado en 2008

Immigrants from the Middle-East have a different form of Type 2 diabetes compared with Swedish patients

artículo científico publicado en 2008

Immune responses to insulin in patients with insulin-dependent diabetes mellitus

artículo científico publicado en 1989

Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood

article published in 2015

Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes

artículo científico publicado en 2012

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

artículo científico publicado en 2017

Impact of exercise intensity and duration on insulin sensitivity in women with T2D.

artículo científico publicado en 2010

Impact of the TCF7L2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia

scientific article published on 10 October 2016

Impact of the peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) Ala203Pro polymorphism on in vivo metabolism, PGC-1beta expression and fibre type composition in human skeletal muscle

scientific article published on 20 June 2007

Impaired cathepsin L gene expression in skeletal muscle is associated with type 2 diabetes

artículo científico publicado en 2003

Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD.

artículo científico publicado en 2017

Impaired insulin-stimulated expression of the glycogen synthase gene in skeletal muscle of type 2 diabetic patients is acquired rather than inherited

scientific article published on 01 April 2000

Impaired mitochondrial function and insulin resistance of skeletal muscle in mitochondrial diabetes.

artículo científico publicado en 2009

Importance of obtaining independent measures of insulin secretion and insulin sensitivity during the same test: results with the Botnia clamp

artículo científico publicado en 2003

Increased concentrations of glycogen synthase protein in skeletal muscle of patients with NIDDM

artículo científico publicado el 1 de julio de 1995

Increased frequency of HLA-Cw4 in type 2 diabetes

artículo científico publicado en 1983

Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture

artículo científico publicado en 2008

Independent measures of insulin secretion and insulin sensitivity during the same test: the glucagon-insulin tolerance test

artículo científico publicado en 2008

Individualizing therapies in type 2 diabetes mellitus based on patient characteristics: what we know and what we need to know

artículo científico publicado en 2010

Influence of Beta-Blocking Drugs on Glucose Metabolism in Hypertensive, Non-Diabetic Patients

artículo científico publicado el 1 de enero de 1983

Influence of Beta-Blocking Drugs on Glucose Metabolism in Patients with Non-Insulin Dependent Diabetes Mellitus

artículo científico publicado el 1 de enero de 1982

Influence of Familial Renal Glycosuria Due to Mutations in the SLC5A2 Gene on Changes in Glucose Tolerance over Time

artículo científico publicado en 2016

Influence of genetic variants on gene expression in human pancreatic islets – implications for type 2 diabetes

article

Influence of glucose and insulin on transcapillary fluid absorption from the arm during lower body negative pressure in man.

artículo científico publicado en 2003

Informed conditioning on clinical covariates increases power in case-control association studies

artículo científico publicado en 2012

Insulin and glucagon secretion in patients with slowly progressing autoimmune diabetes (LADA).

artículo científico publicado en 2000

Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets

artículo científico publicado en 2010

Insulin receptor isotype expression correlates with risk of non-insulin-dependent diabetes

artículo científico publicado el 1 de abril de 1993

Insulin reduces neuronal excitability by turning on GABA(A) channels that generate tonic current

artículo científico publicado en 2011

Insulin resistance in type 2 (non-insulin-dependent) diabetic patients with hypertriglyceridaemia

artículo científico publicado el 1 de diciembre de 1992

Insulin resistance, hypertension and microalbuminuria in patients with type 2 (non-insulin-dependent) diabetes mellitus

artículo científico publicado en 1993

Insulin secretion and action in North Indian women during pregnancy.

artículo científico publicado en 2017

Insulin secretion and insulin sensitivity in diabetic subgroups: studies in the prediabetic and diabetic state

artículo científico publicado en 2000

Insulin sensitivity and insulin secretion in monozygotic and dizygotic twins.

artículo científico publicado en 2000

Insulin sensitivity in adults with growth hormone deficiency and effect of growth hormone treatment

artículo científico publicado en 2005

Insulin-regulated mitochondrial gene expression is associated with glucose flux in human skeletal muscle

artículo científico publicado en 1999

Interaction Between Overweight and Genotypes of HLA, TCF7L2, and FTO in Relation to the Risk of Latent Autoimmune Diabetes in Adults and Type 2 Diabetes

artículo científico publicado en 2019

Interaction between the Asn291Ser variant of the LPL gene and insulin resistance on dyslipidaemia in high risk individuals for Type 2 diabetes mellitus

scientific article published on 01 August 2000

Interaction between the angiotensin-converting enzyme gene insertion/deletion polymorphism and obstructive sleep apnoea as a mechanism for hypertension

artículo científico publicado en 2007

Interactions between glucose and FFA metabolism in man.

artículo científico publicado en 1996

Intraorbital deiodinase type 2 expression is downregulated in chronic phase of Graves' ophthalmopathy

artículo científico publicado en 2012

Intrauterine hyperglycemia modifying the development of (monogenic) diabetes?

artículo científico publicado en 2003

Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort

artículo científico publicado en 2010

Islet Gene View - a tool to facilitate islet research

article

Islet amyloid polypeptide plasma concentrations in individuals at increased risk of developing type 2 (non-insulin-dependent) diabetes mellitus

artículo científico publicado en 1992

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index

artículo científico publicado en 2009

Lack of association between the Gly40Ser polymorphism in the glucagon receptor gene and NIDDM in Finland

scientific article published on 01 October 1995

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Large-scale association study between two coding LRP5 gene polymorphisms and bone phenotypes and fractures in men

article

Latent autoimmune diabetes in adults (LADA)—more than a name

Latent autoimmune diabetes in adults differs genetically from classical type 1 diabetes diagnosed after the age of 35 years

artículo científico publicado en 2010

Less pronounced response to exercise in healthy relatives to type 2 diabetic subjects compared with controls

artículo científico publicado en 2015

Lessons learned from the 1-hour post-load glucose level during the OGTT - Current screening recommendations for dysglycemia should be revised

artículo científico publicado en 2018

Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms

artículo científico publicado en 2014

Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants

scientific article published on 21 November 2019

LifeGene--a large prospective population-based study of global relevance

artículo científico publicado en 2010

Link between GIP and osteopontin in adipose tissue and insulin resistance

artículo científico publicado en 2013

Liver blood dynamics after bariatric surgery: the effects of mixed-meal test and incretin infusions

artículo científico publicado en 2018

Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes

artículo científico publicado en 2020

LoFtool: a gene intolerance score based on loss-of-function variants in 60 706 individuals

artículo científico publicado en 2016

Long-term beneficial effects of glipizide treatment on glucose tolerance in subjects with impaired glucose tolerance

artículo científico publicado en 2006

Long-term effects of guar gum in subjects with non-insulin-dependent diabetes mellitus

scientific article published on 01 October 1993

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

scientific article published on 01 November 2019

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

artículo científico publicado en 2014

Low birthweight is associated with an increased risk of LADA and type 2 diabetes: results from a Swedish case-control study

artículo científico publicado en 2015

Low-cost exercise interventions improve long-term cardiometabolic health independently of a family history of type 2 diabetes: a randomized parallel group trial

scientific article published on 01 November 2020

MECHANISMS IN ENDOCRINOLOGY: Epigenetic modifications and gestational diabetes: a systematic review of published literature

artículo científico publicado en 2017

MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes

artículo científico publicado en 2016

Mapping the Cord Blood Transcriptome of Pregnancies Affected by Early Maternal Anemia to Identify Signatures of Fetal Programming

artículo científico publicado en 2022

Mason diabetes

artículo científico publicado el 1 de enero de 1981

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

artículo científico publicado en 2007

Melatonin receptor 1B gene rs10830963 polymorphism, depressive symptoms and glycaemic traits

article

Melatonin receptors in pancreatic islets: good morning to a novel type 2 diabetes gene

scientific article published on 18 April 2009

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Metabolic Effects of Gastric Bypass Surgery - is it all about Calories?

artículo científico publicado en 2020

Metabolic and Genetic Determinants of Glucose Shape After Oral Challenge in Obese Youths: A Longitudinal Study

scientific article published on 01 February 2020

Metabolic consequences of a family history of NIDDM (the Botnia study): evidence for sex-specific parental effects

artículo científico publicado en 1996

Metabolic consequences of sustained suppression of free fatty acids by acipimox in patients with NIDDM

scientific article published on 01 November 1993

Metabolic control and progression of complications in insulin-dependent diabetic patients after kidney transplantation

artículo científico publicado el 1 de septiembre de 1992

Metabolic effects of metformin in patients with impaired glucose tolerance

artículo científico publicado en 2001

Metabolic impact of a family history of Type 2 diabetes. Results from a European multicentre study (EGIR).

artículo científico publicado en 2001

Metabolite Profiling of LADA Challenges the View of a Metabolically Distinct Subtype

artículo científico publicado en 2016

Metabolite profiling reveals normal metabolic control in carriers of mutations in the glucokinase gene (MODY2)

artículo científico publicado en 2012

Minimal contribution of fasting hyperglycemia to the incidence of type 2 diabetes in subjects with normal 2-h plasma glucose

artículo científico publicado en 2009

Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts

artículo científico publicado en 2014

Modulation of hepatic glucose production by non-esterified fatty acids in type 2 (non-insulin-dependent) diabetes mellitus

scientific article published on 01 June 1991

Mortality in Diabetic Patients Participating in an Ophthalmological Control and Screening Programme

artículo científico publicado el 1 de julio de 1997

Mucosal glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide cell numbers in the super-obese human foregut after gastric bypass

artículo científico publicado en 2015

Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control

scientific article published on 28 November 2018

Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins

artículo científico publicado en 2004

Mutation in the HNF-4alpha gene affects insulin secretion and triglyceride metabolism

artículo científico publicado en 1999

Mutations and variants of the epithelial sodium channel gene in Liddle's syndrome and primary hypertension

artículo científico publicado en 1998

N1-methylnicotinamide is a signalling molecule produced in skeletal muscle coordinating energy metabolism.

artículo científico publicado en 2018

Nateglinide improves early insulin secretion and controls postprandial glucose excursions in a prediabetic population

artículo científico publicado en 2002

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New insights into impaired muscle glycogen synthesis

artículo científico publicado en 2008

New susceptibility loci associated with kidney disease in type 1 diabetes

artículo científico publicado en 2012

No evidence of a relation between 11beta-hydroxysteroid dehydrogenase type 2 activity and salt sensitivity

artículo científico publicado en 2003

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

artículo científico publicado en 2012

No relationship between identified variants in the uncoupling protein 2 gene and energy expenditure

artículo científico publicado en 1998

Non-esterified fatty acids do not contribute to insulin resistance in persons at increased risk of developing type 2 (non-insulin-dependent) diabetes mellitus

artículo científico publicado en 1991

Nonsuppressed Glucagon After Glucose Challenge as a Potential Predictor for Glucose Tolerance

artículo científico publicado en 2016

NordicDB: a Nordic pool and portal for genome-wide control data

artículo científico publicado en 2010

Novel diabetes subgroups - Authors' reply

artículo científico publicado en 2018

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables.

artículo científico publicado en 2018

Nt-proANP in plasma, a marker of salt sensitivity, is reduced in type 2 diabetes patients

artículo científico publicado en 2005

Obesity and insulin resistance in humans: a dose-response study.

artículo científico publicado en 1990

Obstructive sleep apnoea and the risk for coronary heart disease and type 2 diabetes: a longitudinal population-based study in Finland

scientific article published on 15 October 2018

Open chromatin and diabetes risk

scientific article published on 01 March 2010

Ophthalmological follow-up of diabetic patients after kidney transplantation

scientific article published on 01 February 1993

Organ-specific autoimmunity and HLA-DR antigens as markers for beta-cell destruction in patients with type II diabetes

artículo científico publicado en 1988

Outcome of patients with diabetic nephropathy after kidney transplantation

artículo científico publicado en 1987

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

artículo científico publicado en 2010

Overexpression of immediate early genes in active Graves' ophthalmopathy

scientific article published on 31 May 2005

Overweight, obesity and the risk of LADA: results from a Swedish case-control study and the Norwegian HUNT Study.

artículo científico publicado en 2018

P128 Identification de nouveaux polymorphismes génétiques associés au risque de diabète de type 2 chez les obèses et non obèses européens

Pancreatic surgery, not pancreatitis, is the primary cause of diabetes after acute fulminant pancreatitis

artículo científico publicado el 1 de junio de 1992

Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes

artículo científico publicado en 2004

Pathogenesis of type 2 diabetes: the relative contribution of insulin resistance and impaired insulin secretion.

artículo científico publicado en 2000

Peroxisome proliferator-activated receptor-gammaPro12Ala polymorphism and the association with blood pressure in type 2 diabetes: skaraborg hypertension and diabetes project

artículo científico publicado en 2003

Petition to replace current OGTT criteria for diagnosing prediabetes with the 1-hour post-load plasma glucose ≥ 155 mg/dl (8.6 mmol/l)

artículo científico publicado en 2018

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

artículo científico publicado en 2014

Pharmacokinetics and metabolic effects of glibenclamide and glipizide in type 2 diabetics

artículo científico publicado en 1985

Phenotypic and genotypic differences between Indian and Scandinavian women with gestational diabetes mellitus

scientific article published on 29 April 2019

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

artículo científico publicado en 2011

Physical activity reduces the risk of incident type 2 diabetes in general and in abdominally lean and obese men and women: the EPIC-InterAct Study

artículo científico publicado en 2012

Physical activity, genetic susceptibility and the risk of latent autoimmune diabetes in adults and type 2 diabetes

artículo científico publicado en 2020

Physical training in juvenile diabetes

artículo científico publicado en 1982

Plasma ProANP(1-30) reflects salt sensitivity in subjects with heredity for hypertension

artículo científico publicado en 2002

Plasma copeptin and the risk of diabetes mellitus

artículo científico publicado en 2010

Pleiotropic effects of GIP on islet function involve osteopontin

artículo científico publicado en 2011

Polymorphism in the Calpain 10 gene influences glucose metabolism in human fat cells

artículo científico publicado en 2002

Polymorphism in the MHC2TA gene is associated with features of the metabolic syndrome and cardiovascular mortality

artículo científico publicado en 2006

Polymorphism in the angiotensin converting enzyme but not in the angiotensinogen gene is associated with hypertension and type 2 diabetes: the Skaraborg Hypertension and diabetes project

scientific article published on 01 November 1999

Polymorphism in the beta(1)-adrenergic receptor gene and hypertension

artículo científico publicado en 2001

Polymorphisms associated with cholesterol and risk of cardiovascular events

artículo científico publicado en 2008

Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion

artículo científico publicado en 2007

Polymorphisms in α- and β-Adrenergic Receptor Genes, Hypertension, and Obstructive Sleep Apnea: The Skaraborg Sleep Study

artículo científico publicado en 2010

Possible human leukocyte antigen-mediated genetic interaction between type 1 and type 2 Diabetes

artículo científico publicado en 2001

Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants

Precision medicine in Type 2 Diabetes

artículo científico publicado en 2018

Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors

artículo científico publicado en 2009

Prediction of postpartum diabetes in women with gestational diabetes mellitus

artículo científico publicado en 2009

Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes

artículo científico publicado en 2005

Predictors of progression from normoalbuminuria to microalbuminuria in NIDDM.

artículo científico publicado en 1998

Predictors of responses to clinic-based childhood obesity care

artículo científico publicado en 2018

Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells

article published in 2018

Prevalence and risk factors for diabetic retinopathy at diagnosis (DRAD) in patients recently diagnosed with type 2 diabetes (T2D) or latent autoimmune diabetes in the adult (LADA).

artículo científico publicado en 2016

Prevalence of diabetic retinopathy in relation to age at onset of the diabetes, treatment, duration and glycemic control

artículo científico publicado en 1996

Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults

artículo científico publicado en 2009

Progression of retinopathy after change of treatment from oral antihyperglycemic agents to insulin in patients with NIDDM.

artículo científico publicado en 1995

Progression of retinopathy is related to glycaemic control even in patients with mild diabetes mellitus

artículo científico publicado en 1996

Progression to proliferative retinopathy and macular oedema requiring treatment. Assessment of the alternative classification of the Wisconsin Study

artículo científico publicado en 1999

Proliferative responses to insulin antigens in diabetics and controls

artículo científico publicado el 1 de julio de 1983

Proportional proinsulin responses in first-degree relatives of patients with type 2 diabetes mellitus

artículo científico publicado en 1993

Propranolol does not inhibit sulphonylurea-stimulated insulin secretion in patients with non-insulin dependent diabetes mellitus

artículo científico publicado en 1982

Protein biomarkers for the prediction of cardiovascular disease in type 2 diabetes

artículo científico publicado en 2015

Putative role of polymorphisms in UCP1-3 genes for diabetic nephropathy

artículo científico publicado en 2004

Recognition of Maturity-Onset Diabetes of the Young (MODY) in China

artículo científico publicado en 2020

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

artículo científico publicado en 2012

Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.

artículo científico publicado en 2012

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

artículo científico publicado en 2018

Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue

artículo científico publicado en 2009

Regulation of skeletal muscle PPAR delta mRNA expression in twins

artículo científico publicado en 2007

Regulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes--a role for the transcription factor NFAT and phosphodiesterase 3B.

artículo científico publicado en 2012

Relation Between Cycling Exercise Capacity, Fiber-Type Composition, and Lower Extremity Muscle Strength and Muscle Endurance

article

Relationship between B-cell function and HLA antigens in patients with type 2 (non-insulin-dependent) diabetes

artículo científico publicado en 1986

Relationship between abdominal fat compartments and glucose and lipid metabolism in early postmenopausal women

artículo científico publicado en 2001

Relationship between changes in GIP concentrations and changes in insulin and C-peptide concentrations after guar gum therapy

artículo científico publicado en 1986

Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men.

artículo científico publicado en 2005

Relationships of plasma adiponectin level and adiponectin receptors 1 and 2 gene expression to insulin sensitivity and glucose and fat metabolism in monozygotic and dizygotic twins

artículo científico publicado en 2007

Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study

artículo científico publicado en 2021

Reply on new drugs against type 2 diabetes: important to gain experience and knowledge

artículo científico publicado en 2008

Risk factors for mortality in Type II (non-insulin-dependent) diabetes: evidence of a role for neuropathy and a protective effect of HLA-DR4

artículo científico publicado en 1998

Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study

artículo científico publicado en 2019

Roadmap for a precision-medicine initiative in the Nordic region

artículo científico publicado en 2019

Role of osteopontin and its regulation in pancreatic islet

artículo científico publicado en 2017

Role of the FOXC2 -512C>T polymorphism in type 2 diabetes: possible association with the dysmetabolic syndrome

artículo científico publicado en 2005

Role of the Gly460Trp polymorphism of the alpha-adducin gene in primary hypertension in Scandinavians

artículo científico

Roles of chlorpropamide, alcohol and acetaldehyde in determining the chlorpropamide-alcohol flush

artículo científico publicado en 1984

Roux-en-Y gastric bypass versus calorie restriction: support for surgery per se as the direct contributor to altered responses of insulin and incretins to a mixed meal

artículo científico publicado en 2016

SNP in the genome-wide association study hotspot on chromosome 9p21 confers susceptibility to diabetic nephropathy in type 1 diabetes

artículo científico publicado en 2012

Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes

artículo científico publicado en 2012

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Serious life events and the risk of latent autoimmune diabetes in adults (LADA) and Type 2 diabetes

artículo científico publicado en 2017

Serum kidney injury molecule 1 and β-microglobulin perform as well as larger biomarker panels for prediction of rapid decline in renal function in type 2 diabetes

artículo científico publicado en 2018

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Short- and long-term hormonal and metabolic consequences of reversing gastric bypass to normal anatomy in a type 2 diabetes patient

artículo científico publicado en 2015

Short-term exercise training does not stimulate skeletal muscle ATP synthesis in relatives of humans with type 2 diabetes

artículo científico publicado en 2009

Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells.

artículo científico publicado en 2018

Single-Cell Sequencing of Human Pancreatic Islets-New Kids on the Block.

artículo científico publicado en 2016

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

artículo científico publicado en 2008

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

artículo científico publicado en 2009

Sleep duration and insulin resistance in individuals without type 2 diabetes: the PPP-Botnia study

artículo científico publicado en 2014

Smoking and the Risk of LADA: Results From a Swedish Population-Based Case-Control Study

artículo científico publicado en 2016

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

artículo científico publicado en 2012

Stressful life events and the metabolic syndrome: the prevalence, prediction and prevention of diabetes (PPP)-Botnia Study

artículo científico publicado en 2009

Subjective sleep complaints are associated with insulin resistance in individuals without diabetes: the PPP-Botnia Study

artículo científico publicado en 2012

Subtypes of Type 2 Diabetes Determined From Clinical Parameters

artículo científico publicado en 2020

Sulphonylurea antidiabetic drugs. An update of their clinical pharmacology and rational therapeutic use.

artículo científico publicado en 1989

Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway

artículo científico publicado en 2011

Sweetened beverage intake and risk of latent autoimmune diabetes in adults (LADA) and type 2 diabetes

artículo científico publicado en 2016

TCF7L2 is a master regulator of insulin production and processing

artículo científico publicado en 2014

TEMPORAL ORDER OF DISEASE PAIRS AFFECTS SUBSEQUENT DISEASE TRAJECTORIES: THE CASE OF DIABETES AND SLEEP APNEA.

artículo científico publicado en 2016

THOC5: a novel gene involved in HDL-cholesterol metabolism

artículo científico publicado en 2013

Telomere length in blood and skeletal muscle in relation to measures of glycaemia and insulinaemia

artículo científico publicado en 2012

The (in)famous GWAS P-value threshold revisited and updated for low-frequency variants

artículo científico publicado en 2016

The -374 T/A polymorphism in the gene encoding RAGE is associated with diabetic nephropathy and retinopathy in type 1 diabetic patients

artículo científico publicado en 2006

The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

artículo científico publicado en 2013

The FOXC2 C-512T polymorphism is associated with obesity and dyslipidemia.

artículo científico publicado en 2004

The Genetic Landscape of Renal Complications in Type 1 Diabetes

artículo científico publicado en 2016

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people

artículo científico publicado en 2006

The Pro12Ala polymorphism of the PPAR-gamma2 gene affects associations of fish intake and marine n-3 fatty acids with glucose metabolism

artículo científico publicado en 2007

The SLC6A14 gene shows evidence of association with obesity

artículo científico publicado en 2003

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.

artículo científico publicado en 2009

The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects

artículo científico publicado en 2009

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts

artículo científico publicado en 2007

The association of mitochondrial content with prevalent and incident type 2 diabetes.

artículo científico publicado en 2010

The associations of daylight and melatonin receptor 1B gene rs10830963 variant with glycemic traits: the prospective PPP-Botnia study

scientific article published on 14 February 2019

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

artículo científico publicado en 2000

The diabetes susceptibility gene Clec16a regulates mitophagy

scientific journal article

The dysmetabolic syndrome

artículo científico publicado en 2001

The effect of (steroid) immunosuppression on skeletal muscle glycogen metabolism in patients after kidney transplantation

artículo científico publicado en 1996

The effect of an antilipolytic agent (acipimox) on the insulin resistance of lipid and glucose metabolism in hypertriglyceridaemic patients

scientific article published on 01 April 1994

The effect of exercise on urinary excretion of different size proteins in patients with insulin-dependent diabetes mellitus

artículo científico publicado en 1990

The effect of glycaemic control and the introduction of insulin therapy on retinopathy in non-insulin-dependent diabetes mellitus

artículo científico publicado en 1997

The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes

article

The functional impact of G protein-coupled receptor 142 (Gpr142) on pancreatic β-cell in rodent

The genetic abnormality in the beta cell determines the response to an oral glucose load

artículo científico publicado en 2002

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The genetic structure of the Swedish population

artículo científico publicado en 2011

The hormone-sensitive lipase C-60G promoter polymorphism is associated with increased waist circumference in normal-weight subjects

artículo científico publicado en 2006

The impact of Roux-en-Y gastric bypass surgery on normal metabolism in a porcine model

artículo científico publicado en 2017

The impact of low-frequency and rare variants on lipid levels

artículo científico publicado en 2015

The intake of potatoes and glucose metabolism in subjects at high risk for Type 2 diabetes

scientific article published on 01 September 2007

The many faces of diabetes: a disease with increasing heterogeneity

artículo científico publicado en 2013

The metabolic syndrome influences the risk of chronic complications in patients with type II diabetes

artículo científico publicado en 2001

The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity

article

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

artículo científico publicado en 2013

The role of sulphonylurea in combination therapy assessed in a trial of sulphonylurea withdrawal. Scandinavian Insulin-Sulphonylurea Study Group Research Team

artículo científico publicado en 1999

The rs7903146 Variant in the TCF7L2 Gene Increases the Risk of Prediabetes/Type 2 Diabetes in Obese Adolescents by Impairing β-Cell Function and Hepatic Insulin Sensitivity

artículo científico publicado en 2017

The search for putative unifying genetic factors for components of the metabolic syndrome

artículo científico publicado en 2008

The shape of plasma glucose concentration curve during OGTT predicts future risk of type 2 diabetes

artículo científico publicado en 2010

The triglyceride content in skeletal muscle is associated with hepatic but not peripheral insulin resistance in elderly twins

artículo científico publicado en 2012

Therapeutic equivalence of once- and thrice-daily glipizide

artículo científico publicado en 1986

Thyrostimulin (a TSH-like Hormone) expression in orbital and thyroid tissue

artículo científico publicado en 2007

Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion

artículo científico publicado en 2009

Tissue-specific alternative splicing of TCF7L2.

artículo científico publicado en 2009

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Transferability of tag SNPs in genetic association studies in multiple populations

scientific article published on 22 October 2006

Treatment failures in patients with type 2 (non-insulin-dependent) diabetes.

artículo científico publicado en 1988

Treatment with a thiazolidinedione increases eye protrusion in a subgroup of patients with type 2 diabetes.

artículo científico publicado en 2006

Turning Vice into Virtue: Using Batch-Effects to Detect Errors in Large Genomic Data Sets

artículo científico publicado en 2018

Turning vice into virtue: Using Batch-Effects to Detect Errors in Large Genomic Datasets

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

artículo científico publicado en 2010

Two New Mutations in the <i>CEL</i> Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases

artículo científico publicado en 2021

Two common genetic variants near nuclear-encoded OXPHOS genes are associated with insulin secretion in vivo

artículo científico publicado en 2011

Two-step approach for the prediction of future type 2 diabetes risk

artículo científico publicado en 2011

Type 2 diabetes and risk for periodontal disease: a role for dental health awareness

article

Type 2 diabetes mellitus

article

Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes

article

UKPDS 19: Heterogeneity in NIDDM: separate contributions of IRS-1 and b3-adrenergic-receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations

article

Underlying genetic models of inheritance in established type 2 diabetes associations

artículo científico publicado en 2009

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.

artículo científico publicado en 2009

Update on Current Care Guideline. Diabetes

artículo científico publicado en 2016

Upper body muscle strength and endurance in relation to peak exercise capacity during cycling in healthy sedentary male subjects

scientific article published on 01 May 2011

Urinary excretion of kappa light chains in patients with diabetes mellitus

artículo científico publicado en 1990

Urinary excretion of plasma proteins in diabetic subjects. Increased excretion of kappa light chains in diabetic patients with and without proliferative retinopathy

artículo científico publicado en 1985

Uromodulin gene variant is associated with type 2 diabetic nephropathy

article

Use of Swedish smokeless tobacco (snus) and the risk of Type 2 diabetes and latent autoimmune diabetes of adulthood (LADA).

artículo científico publicado en 2016

Validation of a multi-marker model for the prediction of incident type 2 diabetes mellitus: combined results of the Inter99 and Botnia studies

artículo científico publicado en 2011

Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents

artículo científico publicado en 2011

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

artículo científico publicado en 2008

Variants in MTNR1B influence fasting glucose levels

artículo científico publicado en 2008

Variants in the FFAR1 gene are associated with beta cell function

artículo científico publicado en 2007

Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels

artículo científico publicado en 2002

Variation in GYS1 interacts with exercise and gender to predict cardiovascular mortality

artículo científico publicado en 2007

Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans

artículo científico publicado en 2015

Variation in the adiponutrin gene influences its expression and associates with obesity

artículo científico publicado en 2006

Variation in the calpain-10 gene is associated with elevated triglyceride levels and reduced adipose tissue messenger ribonucleic acid expression in obese Swedish subjects.

artículo científico publicado en 2004

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

artículo científico publicado en 2008

Vigorous Physical Activity May Be Important for the Insulin Sensitivity in Immigrants from the Middle East and Native Swedes

Vigorous physical activity may be important for the insulin sensitivity in immigrants from the Middle East and native Swedes

artículo científico publicado en 2014

Weight loss by very-low-calorie diets: effects on substrate oxidation, energy expenditure, and insulin sensitivity in obese subjects

artículo científico publicado en 1992

What do healthcare professionals need to turn risk models for type 2 diabetes into usable computerized clinical decision support systems? Lessons learned from the MOSAIC project

scientific article published on 16 August 2019

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

artículo científico publicado en 2014

Worse glycaemic control in LADA patients than in those with type 2 diabetes, despite a longer time on insulin therapy

artículo científico publicado en 2012

Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis study

artículo científico publicado en 2012

[Gestational diabetes and adult type of diabetes with relative insulin resistance]

artículo científico publicado en 1994

[Introduction of the new criteria for diabetes mellitus was not premature]

scientific article published on 01 September 1999

[MODY--an autosomal dominant type of diabetes. Diagnosis via genetic testing results in better treatment]

scientific article published on 01 September 2007

[Microalbuminuria in diabetic patients]

scientific article published on 01 January 1995

[New diagnosis and classification of diabetes. Nothing is longer as it was before--but why?]

artículo científico publicado en 1998

[New diagnostic methods and classification of diabetes. Not many changes--but why?]

artículo científico publicado en 1998

[New drugs against insulin resistance]

artículo científico publicado en 1998

[Rapid blood glucose changes and the glycosylated hemoglobins]

scientific article published on 01 January 1983

[Treatment of infectious diseases in a public health care center]

scientific article published on 01 January 1980

[Type 2 diabetes--hereditary destiny or punishment of the affluent society?].

artículo científico publicado en 2014

[Why do we fail to treat type II diabetes?]

scientific article published on 01 January 1988

α-Hydroxybutyric Acid Is a Selective Metabolite Biomarker of Impaired Glucose Tolerance

artículo científico publicado en 2016

γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes

artículo científico publicado en 2012

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004

artículo