Lista de obras -

A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects

artículo científico publicado en 2013

A phenome-wide association study to discover pleiotropic effects of , , and

A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers

artículo científico publicado en 2018

Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records

artículo científico publicado en 2016

Association of Genetic Risk of Obesity with Postoperative Complications Using Mendelian Randomization

artículo científico publicado en 2020

Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate

artículo científico publicado en 2011

Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data

artículo científico publicado en 2016

Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and multivariate methods on 43,870 individuals from the eMERGE network

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

artículo científico publicado en 2017

Electronic medical records and genomics (eMERGE) network exploration in cataract: several new potential susceptibility loci.

artículo científico publicado en 2014

Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records

artículo científico publicado en 2013

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

artículo científico publicado en 2016

Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans

artículo científico publicado en 2013

Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network

artículo científico publicado en 2014

Genetic variation associated with circulating monocyte count in the eMERGE Network

artículo científico publicado en 2013

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

artículo científico publicado en 2016

High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE

artículo científico publicado en 2012

Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)

artículo científico publicado en 2015

Imputation and quality control steps for combining multiple genome-wide datasets

artículo científico publicado en 2014

Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes

artículo científico publicado en 2017

LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

artículo científico publicado en 2016

Loss-of-function mutations in APOC3, triglycerides, and coronary disease

artículo científico publicado en 2014

Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data

artículo científico publicado en 2013

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

artículo científico publicado en 2016

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

artículo científico publicado en 2016

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Penetrance of Hemochromatosis in HFE Genotypes Resulting in p.Cys282Tyr and p.[Cys282Tyr];[His63Asp] in the eMERGE Network

artículo científico publicado en 2015

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

artículo científico publicado en 2014

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

artículo científico publicado en 2016

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms

artículo científico publicado en 2016

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

artículo científico publicado en 2013

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future ⬇️

artículo científico publicado el 6 de junio de 2013

The phenotypic legacy of admixture between modern humans and Neandertals

artículo científico publicado en 2016

The polygenic architecture of left ventricular mass mirrors the clinical epidemiology

scientific article published on 05 May 2020

Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study

artículo científico publicado en 2011

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

artículo científico publicado en 2014

eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants

artículo científico publicado en 2016

eMERGEing progress in genomics-the first seven years

artículo científico publicado en 2014

Lista de obras de

A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects

A phenome-wide association study to discover pleiotropic effects of , , and

A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers

Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records

Association of Genetic Risk of Obesity with Postoperative Complications Using Mendelian Randomization

Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate

Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data

Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and multivariate methods on 43,870 individuals from the eMERGE network

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

Electronic medical records and genomics (eMERGE) network exploration in cataract: several new potential susceptibility loci.

Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans

Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network

Genetic variation associated with circulating monocyte count in the eMERGE Network

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE

Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)

Imputation and quality control steps for combining multiple genome-wide datasets

Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes

LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

Loss-of-function mutations in APOC3, triglycerides, and coronary disease

Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

Penetrance of Hemochromatosis in HFE Genotypes Resulting in p.Cys282Tyr and p.[Cys282Tyr];[His63Asp] in the eMERGE Network

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future ⬇️

The phenotypic legacy of admixture between modern humans and Neandertals

The polygenic architecture of left ventricular mass mirrors the clinical epidemiology

Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants

eMERGEing progress in genomics-the first seven years