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Lista de obras de Matthias Hentze

'High vault-age': non-coding RNA control of autophagy

artículo científico publicado en 2020

3' end mRNA processing: molecular mechanisms and implications for health and disease

artículo científico publicado en 2008

3' end processing of the prothrombin mRNA in thrombophilia

artículo científico publicado en 2006

5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion.

artículo científico publicado en 2014

A Genetically Encoded Diazirine Analogue for RNA-Protein Photo-crosslinking

scientific article published on 26 November 2019

A Poly(A) Tail-Responsive In Vitro System for Cap- or IRES-Driven Translation From HeLa Cells

article

A Red Carpet for Iron Metabolism.

artículo científico publicado en 2017

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells

artículo científico publicado en 2008

A brave new world of RNA-binding proteins.

artículo científico publicado en 2018

A chemiluminescence-based reporter system to monitor nonsense-mediated mRNA decay

artículo científico publicado en 2006

A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron

artículo científico publicado en 1987

A co-repressor assembly nucleated by Sex-lethal in the 3'UTR mediates translational control of Drosophila msl-2 mRNA

artículo científico publicado en 2003

A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain

artículo científico publicado en 2007

A dual inhibitory mechanism restricts msl-2 mRNA translation for dosage compensation in Drosophila

artículo científico publicado en 2005

A model for the structure and functions of iron-responsive elements

article

A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation

artículo científico publicado en 2015

A new era for the RNA world. Conference: RNA 2000.

artículo científico publicado en 2000

A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

artículo científico publicado en 2000

A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia.

artículo científico publicado en 2015

A perfect message: RNA surveillance and nonsense-mediated decay

artículo científico publicado en 1999

A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA)

artículo científico publicado en 2006

A translational repression assay procedure (TRAP) for RNA-protein interactions in vivo

artículo científico publicado en 1998

A versatile assay for RNA-binding proteins in living cells

artículo científico publicado en 2014

Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function

artículo científico publicado en 2013

Abnormally spliced beta-globin mRNAs: a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay

artículo científico publicado en 2002

Activation of iron regulatory protein-1 by oxidative stress in vitro

scientific article published on September 1998

Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2)

artículo científico publicado en 2005

An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.

artículo científico publicado en 2004

An efficient factor-depleted mammalian in vitro translation system

An interview with Matthias Hentze ⬇️

artículo científico publicado el 6 de octubre de 2012

Anti-hemojuvelin antibody corrects anemia caused by inappropriately high hepcidin levels

artículo científico publicado en 2016

Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction

artículo científico publicado en 2019

Automated high-throughput RNAi screening in human cells combined with reporter mRNA transfection to identify novel regulators of translation

artículo científico publicado en 2012

Bacteriophage and spliceosomal proteins function as position-dependent cis/trans repressors of mRNA translation in vitro

artículo científico publicado en 1992

Binary specification of nonsense codons by splicing and cytoplasmic translation

artículo científico publicado en 1998

Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA

scientific article published in Science

Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD.

artículo científico publicado en 2009

Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles

artículo científico publicado en 2006

Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1

artículo científico publicado en 2007

Cell-autonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism

artículo científico publicado en 2008

Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin

Chapter 23 Tethering Assays to Investigate Nonsense‐Mediated mRNA Decay Activating Proteins

artículo científico publicado en 2008

Characterization of the African swine fever virus decapping enzyme during infection.

artículo científico publicado en 2017

Chromosomal localization of nucleic acid-binding proteins by affinity mapping: assignment of the IRE-binding protein gene to human chromosome 9

artículo científico publicado en 1989

Circular RNAs: splicing’s enigma variations ⬇️

artículo científico publicado el 5 de marzo de 2013

Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene

artículo científico publicado en 1986

Complex formation between a cytoplasmic protein and the ferritin mRNA regulates translation initiation

artículo científico publicado en 1990

Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5' untranslated region

artículo científico publicado en 2007

Complexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells

artículo científico publicado en 2003

Comprehensive Identification of RNA-Binding Domains in Human Cells.

artículo científico publicado en 2016

Comprehensive Identification of RNA-Binding Proteins by RNA Interactome Capture

artículo científico publicado en 2016

Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production

scientific article published on 29 April 2020

Conservation of aconitase residues revealed by multiple sequence analysis. Implications for structure/function relationships

artículo científico publicado en 1996

Construction of regulatable picornavirus IRESes as a test of current models of the mechanism of internal translation initiation

artículo científico publicado en 2001

Control of oskar mRNA translation by Bruno in a novel cell-free system from Drosophila ovaries

artículo científico publicado en 2000

Coordination of cellular iron metabolism by post-transcriptional gene regulation

artículo científico publicado en 1992

Cytoplasmic regulatory functions of the KH-domain proteins hnRNPs K and E1/E2.

artículo científico publicado en 1998

Determinants and regulation of cytoplasmic mRNA stability in eukaryotic cells

artículo científico publicado en 1991

Determination of mRNA fate by different RNA polymerase II promoters

artículo científico publicado en 1993

Differences in the regulation of iron regulatory protein-1 (IRP-1) by extra- and intracellular oxidative stress

artículo científico publicado en 1997

Differential regulation of two related RNA-binding proteins, iron regulatory protein (IRP) and IRPB.

artículo científico publicado en 1995

Disassembly of exon junction complexes by PYM

artículo científico publicado en 2009

Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture

scientific article published in Nature Communications

Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation

artículo científico publicado en 2007

Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression

artículo científico publicado en 2009

Drosophila sex-lethal inhibits the stable association of the 40S ribosomal subunit with msl-2 mRNA.

artículo científico publicado en 2003

Dual function of UPF3B in early and late translation termination

artículo científico publicado en 2017

Dual function of the messenger RNA cap structure in poly(A)-tail-promoted translation in yeast ⬇️

artículo científico publicado el 2 de abril de 1998

EMBO Molecular Medicine: Conquering new frontiers

artículo científico publicado en 2009

ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation

artículo científico publicado en 2001

Effect of heparin contained in preparations of small cytoplasmic RNAs on cell-free translation

scientific article published in Journal of Biological Chemistry

Effect of nitric oxide on expression of transferrin receptor and ferritin and on cellular iron metabolism in K562 human erythroleukemia cells

artículo científico publicado en 1995

Elisa Izaurralde 1959–2018

scholarly article by Matthias Hentze published in June 2018

Enhanced degradation of cathepsin D synthesized in the presence of the threonine analog beta-hydroxynorvaline

artículo científico publicado en 1984

Enhancement of IRES-Mediated Translation of the c-myc and BiP mRNAs by the Poly(A) Tail Is Independent of Intact eIF4G and PABP

article published in 2004

Enzymes as RNA-binding proteins: a role for (di)nucleotide-binding domains?

artículo científico publicado en 1994

Erratum to: Insights into the design and interpretation of iCLIP experiments.

artículo científico publicado en 2017

Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation

artículo científico publicado en 2005

Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins.

artículo científico publicado en 2016

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

artículo científico publicado en 2005

Expression of epithelial cell iron-related genes upon infection by Neisseria meningitidis

artículo científico publicado en 2004

Expression of the subgenomic hepatitis C virus replicon alters iron homeostasis in Huh7 cells

artículo científico publicado en 2007

FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation

artículo científico publicado en 2015

Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen

artículo científico publicado en 2015

Fertility facts: male and female germ cell development requires translational control by CPEB.

artículo científico publicado en 2001

Finding the hairpin in the haystack: searching for RNA motifs

artículo científico publicado en 1995

From cis-regulatory elements to complex RNPs and back

artículo científico publicado en 2012

From factors to mechanisms: translation and translational control in eukaryotes.

artículo científico publicado en 1999

From transcript to protein

artículo científico publicado en 1996

Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation

artículo científico publicado en 2006

Generation of conditional alleles of the murineiron regulatory protein (IRP)-1 and -2 genes

article

Generation of stable mRNA fragments and translation of N-truncated proteins induced by antisense oligodeoxynucleotides

artículo científico

Genetics. IRES unplugged

artículo científico publicado en 2016

Geschwisterpaar italienischer Abstammung mit Hyperferritin�mie und Katarakt

scientific article published on 01 April 2000

Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila

artículo científico publicado en 2016

HFE downregulates iron uptake from transferrin and induces iron-regulatory protein activity in stably transfected cells.

artículo científico publicado en 1999

Hfe acts in hepatocytes to prevent hemochromatosis.

artículo científico publicado en 2008

Homodirectional changes in transcriptome composition and mRNA translation induced by rapamycin and heat shock

artículo científico publicado en 2003

Human Cytoplasmic Aconitase (Iron Regulatory Protein 1) Is Converted into Its [3Fe-4S] Form by Hydrogen Peroxidein Vitrobut Is Not Activated for Iron-responsive Element Binding

artículo científico publicado en 1999

IRP-1 Binding to Ferritin mRNA Prevents the Recruitment of the Small Ribosomal Subunit by the Cap-Binding Complex eIF4F

article

IRP1 activation by extracellular oxidative stress in the perfused rat liver

artículo científico publicado en 2001

IRP1-independent alterations of cardiac iron metabolism in doxorubicin-treated mice

artículo científico publicado en 2006

Identification of RNA-binding Proteins in Macrophages by Interactome Capture

artículo científico

Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap.

artículo científico publicado en 2017

Identification of target mRNAs of regulatory RNA-binding proteins using mRNP immunopurification and microarrays

artículo científico publicado en 2007

Improved binding site assignment by high-resolution mapping of RNA-protein interactions using iCLIP

artículo científico publicado en 2015

In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings

artículo científico publicado en 2016

In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation

artículo científico publicado en 2009

Increased efficiency of mRNA 3′ end formation: a new genetic mechanism contributing to hereditary thrombophilia

Influence of altered transcription on the translational control of human ferritin expression

artículo científico publicado en 1987

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

artículo científico publicado en 2012

Insights into the design and interpretation of iCLIP experiments

artículo científico publicado en 2017

Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway

artículo científico publicado en 2002

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

artículo científico publicado en 2008

Internal ribosome entry sequence-mediated translation initiation triggers nonsense-mediated decay

artículo científico publicado en 2006

Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages.

artículo científico publicado en 2017

Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection

artículo científico publicado en 2015

Iron Regulatory Proteins Secure Mitochondrial Iron Sufficiency and Function

Iron homeostasis in the brain: complete iron regulatory protein 2 deficiency without symptomatic neurodegeneration in the mouse

artículo científico publicado en 2006

Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C Virus.

artículo científico publicado en 2005

Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin

artículo científico publicado en 2003

Iron regulates nitric oxide synthase activity by controlling nuclear transcription

artículo científico publicado en 1994

Iron regulation and the cell cycle: identification of an iron-responsive element in the 3'-untranslated region of human cell division cycle 14A mRNA by a refined microarray-based screening strategy

artículo científico publicado en 2006

Iron regulatory factor--the conductor of cellular iron regulation

artículo científico publicado en 1993

Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency.

artículo científico publicado en 2015

Iron regulatory protein prevents binding of the 43S translation pre-initiation complex to ferritin and eALAS mRNAs.

artículo científico publicado en 1994

Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins

artículo científico publicado en 2011

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria

artículo científico publicado en 2014

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria

artículo científico publicado en 2014

Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum

scientific journal article

Iron regulatory proteins control a mucosal block to intestinal iron absorption

artículo científico publicado en 2013

Iron-dependent regulation of the divalent metal ion transporter

artículo científico publicado en 2001

Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity

artículo científico publicado en 2004

Iron-regulatory protein-1 (IRP-1) is highly conserved in two invertebrate species--characterization of IRP-1 homologues in Drosophila melanogaster and Caenorhabditis elegans

artículo científico publicado en 1998

Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency

artículo científico publicado en 2007

Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure

artículo científico publicado en 2016

Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation

scientific article published in Science

Iron-sulfur clusters and oxidant stress responses

article

Iron-sulphur clusters as genetic regulatory switches: the bifunctional iron regulatory protein-1.

artículo científico publicado en 1996

Is congenital secondary erythrocytosis/polycythemia caused by activating mutations within the HIF-2 alpha iron-responsive element?

artículo científico publicado en 2007

Ligand-induced Structural Alterations in Human Iron Regulatory Protein-1 Revealed by Protein Footprinting

artículo científico publicado en 1999

Lipoxygenase mRNA silencing in erythroid differentiation: The 3'UTR regulatory complex controls 60S ribosomal subunit joining

artículo científico publicado en 2001

Making sense of nonsense

artículo científico publicado en 2013

Mechanism of escape from nonsense-mediated mRNA decay of human beta-globin transcripts with nonsense mutations in the first exon

artículo científico publicado en 2011

Mechanism of translational regulation by miR-2 from sites in the 5' untranslated region or the open reading frame

artículo científico publicado en 2010

Mechanisms for posttranscriptional regulation by iron-responsive elements and iron regulatory proteins.

artículo científico publicado en 1997

Metabolic Enzymes Enjoying New Partnerships as RNA-Binding Proteins

artículo científico publicado en 2015

Mice with hepcidin-resistant ferroportin accumulate iron in the retina

artículo científico publicado en 2015

Modulation of ferritin H-chain expression in Friend erythroleukemia cells: transcriptional and translational regulation by hemin

artículo científico publicado en 1992

Modulation of the RNA-binding activity of a regulatory protein by iron in vitro: switching between enzymatic and genetic function?

artículo científico publicado en 1992

Molecular analysis of iron overload in β2-microglobulin-deficient mice

article

Molecular cloning and characterisation of a novel duodenal-specific gene implicated in iron absorption

artículo científico publicado en 1998

Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress

artículo científico publicado en 2003

NMD: RNA biology meets human genetic medicine

artículo científico publicado en 2010

New ways of initiating translation in eukaryotes.

artículo científico publicado en 2001

Nitric oxide and oxidative stress (H2O2) control mammalian iron metabolism by different pathways

artículo científico publicado en 1996

Nitric oxide and the post-transcriptional control of cellular iron traffic

artículo científico publicado en 1994

Nitric oxide signaling to iron-regulatory protein: direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts

artículo científico publicado en 1995

Nonsense-mediated decay approaches the clinic

artículo científico publicado en 2004

Nonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knife

artículo científico publicado en 2004

Novel functions for 'nuclear factors' in the cytoplasm: the Sex-lethal paradigm

artículo científico publicado en 1997

Nuclear degradation of nonsense mutated beta-globin mRNA: a post-transcriptional mechanism to protect heterozygotes from severe clinical manifestations of beta-thalassemia?

artículo científico publicado en 1995

Overcoming inhibitions. Translational Control sponsored by the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA, September 13-17, 1989.

artículo científico publicado en 1990

Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction

artículo científico publicado en 1989

PABP and the poly(A) tail augment microRNA repression by facilitated miRISC binding

artículo científico publicado en 2012

Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond

artículo científico

Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13.

artículo científico publicado en 1997

Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7

artículo científico publicado en 2003

Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins.

artículo científico publicado en 2014

Physiologic systemic iron metabolism in mice deficient for duodenal Hfe

artículo científico publicado en 2007

Picornavirus IRESes and the poly(A) tail jointly promote cap-independent translation in a mammalian cell-free system

artículo científico publicado en 2000

Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins

artículo científico publicado en 2020

Poly(A)-tail-promoted translation in yeast: implications for translational control.

artículo científico publicado en 1998

Position is the critical determinant for function of iron-responsive elements as translational regulators

artículo científico publicado en 1992

Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function

artículo científico publicado en 2002

Probing the structure of the regulatory region of human transferrin receptor messenger RNA and its interaction with iron regulatory protein-1.

artículo científico publicado en 1997

Protein synthesis. Believe it or not-translation in the nucleus

artículo científico publicado en 2001

Proteins binding to 5' untranslated region sites: a general mechanism for translational regulation of mRNAs in human and yeast cells

artículo científico publicado en 1994

Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay

artículo científico publicado en 2016

RNA-binding proteins in Mendelian disease.

artículo científico

RNA-binding proteins in human genetic disease

artículo científico publicado en 2020

Rapid responses to oxidative stress mediated by iron regulatory protein.

artículo científico publicado en 1995

Rat duodenal IRP1 activity and iron absorption in iron deficiency and after HO perfusion

scientific journal article

Recombinant iron-regulatory factor functions as an iron-responsive-element-binding protein, a translational repressor and an aconitase. A functional assay for translational repression and direct demonstration of the iron switch

scientific article published on 01 December 1993

Regulated poly(A) tail shortening in somatic cells mediated by cap-proximal translational repressor proteins and ribosome association.

artículo científico publicado en 1997

Regulated ribosomal frameshifting by an RNA-protein interaction

artículo científico publicado en 1996

Regulation of interaction of the iron-responsive element binding protein with iron-responsive RNA elements

artículo científico publicado en 1989

Regulation of iron metabolism in higher eukaryotes: iron–sulfur centers as genetic switches

Regulation of protein synthesis by mRNA structure

artículo científico publicado en 1994

Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis

artículo científico publicado en 2003

Relationships and distinctions in iron-regulatory networks responding to interrelated signals

artículo científico publicado en 2002

Resistance of ferroportin to hepcidin binding causes exocrine pancreatic failure and fatal iron overload

artículo científico publicado en 2014

Ribosomal pausing and scanning arrest as mechanisms of translational regulation from cap-distal iron-responsive elements

artículo científico publicado en 1999

SIREs: searching for iron-responsive elements.

artículo científico publicado en 2010

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression

artículo científico publicado en 2009

STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation

artículo científico publicado en 2007

Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway.

artículo científico publicado en 2010

Sex-lethal imparts a sex-specific function to UNR by recruiting it to the msl-2 mRNA 3' UTR: translational repression for dosage compensation

artículo científico publicado en 2006

Silica-based solid-phase extraction of cross-linked nucleic acid-bound proteins

artículo científico publicado en 2018

Specific RNP capture with antisense LNA/DNA mixmers.

artículo científico publicado en 2017

Splicing and 3' end formation in the definition of nonsense-mediated decay-competent human beta-globin mRNPs

artículo científico publicado en 2001

Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals

artículo científico publicado en 2007

Stimulation of IRE-BP activity of IRF by tetrahydrobiopterin and cytokine dependent induction of nitric oxide synthase

artículo científico publicado en 1994

Studying translational control in Drosophila cell-free systems

artículo científico publicado en 2007

System-wide identification of RNA-binding proteins by interactome capture.

artículo científico publicado en 2013

Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma

artículo científico publicado en 2024

Systematic genomic screening and analysis of mRNA in untranslated regions and mRNA precursors: combining experimental and computational approaches

artículo científico publicado en 1998

Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network

artículo científico publicado en 2008

Systems analysis of iron metabolism: the network of iron pools and fluxes

artículo científico publicado en 2010

Target-specific arrest of mRNA translation by antisense 2'-O-alkyloligoribonucleotides

artículo científico publicado en 1994

Targeted mutagenesis of the murine IRP1 and IRP2 genes reveals context-dependent RNA processing differences in vivo.

artículo científico publicado en 2004

Tethered-function analysis reveals that elF4E can recruit ribosomes independent of its binding to the cap structure.

artículo científico publicado en 2001

The Cardiomyocyte RNA-Binding Proteome: Links to Intermediary Metabolism and Heart Disease.

artículo científico publicado en 2016

The Drosophila splicing regulator sex-lethal directly inhibits translation of male-specific-lethal 2 mRNA

artículo científico publicado en 1998

The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest

artículo científico publicado en 2018

The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption

artículo científico publicado en 2013

The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays

artículo científico publicado en 2010

The REM phase of gene regulation

artículo científico publicado en 2010

The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance

artículo científico publicado en 2019

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.

artículo científico publicado en 2018

The RNA-binding protein repertoire of embryonic stem cells.

artículo científico publicado en 2013

The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs

artículo científico publicado en 2015

The SXL-UNR corepressor complex uses a PABP-mediated mechanism to inhibit ribosome recruitment to msl-2 mRNA.

artículo científico publicado en 2009

The Small Non-coding Vault RNA1-1 Acts as a Riboregulator of Autophagy

scientific article published on 14 February 2019

The Yeast Nuclear Cap Binding Complex Can Interact with Translation Factor eIF4G and Mediate Translation Initiation

scientific article published on 01 July 2000

The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway

artículo científico publicado en 2007

The actin binding protein profilin 2 is a novel regulator of iron homeostasis

artículo científico publicado en 2017

The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion

artículo científico publicado en 2016

The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

artículo científico publicado en 2012

The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay

artículo científico publicado en 2009

The human intronless melanocortin 4-receptor gene is NMD insensitive

artículo científico publicado en 2002

The interaction of the cap-binding complex (CBC) with eIF4G is dispensable for translation in yeast

artículo científico publicado en 2003

The iron-responsive element binding protein: a method for the affinity purification of a regulatory RNA-binding protein

artículo científico publicado en 1989

The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis. Evidence for function as the binding site for a translational repressor

scientific article published in Journal of Biological Chemistry

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

artículo científico publicado en 2011

The molecular circuitry regulating the switch between iron deficiency and overload in mice

artículo científico

The prothrombin 20209 C-->T mutation in Jewish-Moroccan Caucasians: molecular analysis of gain-of-function of 3' end processing

artículo científico publicado en 2006

The prothrombin 3'end formation signal reveals a unique architecture that is sensitive to thrombophilic gain-of-function mutations

artículo científico publicado en 2004

The role of ABCE1 in eukaryotic posttermination ribosomal recycling

artículo científico publicado en 2010

The role of the 5' untranslated region of eukaryotic messenger RNAs in translation and its investigation using antisense technologies.

artículo científico publicado en 1994

The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD).

artículo científico publicado en 2006

Tolerable upper intakes for dietary iron set by the US Food and Nutrition Board

artículo científico publicado en 2002

Translation driven by an eIF4G core domain in vivo

artículo científico publicado en 1999

Translation initiation by the c-myc mRNA internal ribosome entry sequence and the poly(A) tail.

artículo científico publicado en 2008

Translational activation of uncapped mRNAs by the central part of human eIF4G is 5' end-dependent

artículo científico publicado en 1998

Translational control by iron-responsive elements.

artículo científico publicado en 1994

Translational control of 15-lipoxygenase and msl-2 mRNAs: single regulators or corepressor assemblies?

artículo científico publicado en 2001

Translational control of dosage compensation in Drosophila by Sex-lethal: cooperative silencing via the 5' and 3' UTRs of msl-2 mRNA is independent of the poly(A) tail

artículo científico publicado en 1999

Translational control via protein-regulated upstream open reading frames

artículo científico publicado en 2011

Translational regulation by mRNA/protein interactions in eukaryotic cells: ferritin and beyond

artículo científico publicado en 1993

Translational regulation of ferritin biosynthesis by iron: a review

artículo científico publicado en 1991

Translational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elements

artículo científico publicado en 1996

Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway

artículo científico

Translational regulation: versatile mechanisms for metabolic and developmental control.

artículo científico publicado en 1995

Translational repression by a complex between the iron-responsive element of ferritin mRNA and its specific cytoplasmic binding protein is position-dependent in vivo

artículo científico publicado en 1990

Translational repression by the human iron-regulatory factor (IRF) in Saccharomyces cerevisiae.

artículo científico publicado en 1993

Two to tango: regulation of Mammalian iron metabolism

artículo científico publicado en 2010

Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling

artículo científico publicado en 2014

Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2

artículo científico publicado en 2009

Using the λN Peptide to Tether Proteins to RNAs

scientific article published on 01 January 2004

Vault RNA emerges as a regulator of selective autophagy

artículo científico publicado en 2019

Vault RNA1-1 riboregulates the autophagic function of p62 by binding to lysine 7 and arginine 21, both of which are critical for p62 oligomerization

artículo científico publicado en 2022

Y14 and hUpf3b form an NMD-activating complex

artículo científico publicado en 2003

[25] Translational repression assay procedure: A method to study RNA-protein interactions in yeast

artículo científico publicado en 2000

c-Src-mediated phosphorylation of hnRNP K drives translational activation of specifically silenced mRNAs

artículo científico publicado en 2002

eIF4G: a multipurpose ribosome adapter?

artículo científico publicado en 1997

mRNA 3'end processing: A tale of the tail reaches the clinic

artículo científico publicado en 2014

mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end.

artículo científico

miChip: A microarray platform for expression profiling of microRNAs based on locked nucleic acid (LNA) oligonucleotide capture probes

miChip: an array-based method for microRNA expression profiling using locked nucleic acid capture probes

artículo científico publicado en 2008

microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells

artículo científico publicado en 2009

p38 MAPK controls prothrombin expression by regulated RNA 3' end processing

artículo científico publicado en 2011

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