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A Broad-Spectrum Inhibitor of CRISPR-Cas9.

artículo científico publicado en 2017

A bacterial Argonaute with noncanonical guide RNA specificity

artículo científico publicado en 2016

A novel STING1 variant causes a recessive form of STING-associated vasculopathy with onset in infancy (SAVI)

scientific article published on 13 July 2020

African origin of the malaria parasite Plasmodium vivax

artículo científico publicado en 2014

Analysis of human cGAS activity and structure

scientific article published on 02 May 2019

Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling

artículo científico publicado en 2015

Architecture and regulation of negative-strand viral enzymatic machinery

artículo científico publicado en 2012

Arenavirus Z protein controls viral RNA synthesis by locking a polymerase-promoter complex

artículo científico publicado en 2011

Assembly of a functional Machupo virus polymerase complex

artículo científico publicado en 2010

Bacterial cGAS-like enzymes synthesize diverse nucleotide signals

scientific article published on 20 February 2019

CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection

artículo científico publicado en 2020

Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity

artículo científico publicado en 2014

Conserved strategies for pathogen evasion of cGAS-STING immunity

scientific article published on 15 April 2020

Dynamic Control of X Chromosome Conformation and Repression by a Histone H4K20 Demethylase.

artículo científico publicado en 2017

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

artículo científico publicado en 2011

Ebolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry

artículo científico publicado en 2011

Foreign DNA capture during CRISPR-Cas adaptive immunity

artículo científico publicado en 2015

Foreign DNA capture during CRISPR–Cas adaptive immunity

artículo científico publicado en 2016

Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin

artículo científico publicado en 2010

Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation

scientific article published on 01 April 2019

Molecular architecture of the vesicular stomatitis virus RNA polymerase.

artículo científico publicado en 2010

Molecular epidemiology of simian immunodeficiency virus infection in wild-living gorillas

artículo científico publicado en 2009

Origin of the human malaria parasite Plasmodium falciparum in gorillas

artículo científico publicado en 2010

Origin of the human malaria parasite Plasmodium falciparum in gorillas.

artículo científico publicado en 2010

Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity

artículo científico publicado en 2022

Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA

scientific article published on 28 February 2019

Publisher Correction: Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling

scientific article published on 01 May 2019

Recurrent Loss-of-Function Mutations Reveal Costs to OAS1 Antiviral Activity in Primates

artículo científico publicado en 2019

Ribose 2'-O Methylation of the Vesicular Stomatitis Virus mRNA Cap Precedes and Facilitates Subsequent Guanine-N-7 Methylation by the Large Polymerase Protein

artículo científico publicado en 2009

STING cyclic dinucleotide sensing originated in bacteria

scientific article published on 02 September 2020

Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity

artículo científico publicado en 2020

Structure and mechanism of a Hypr GGDEF enzyme that activates cGAMP signaling to control extracellular metal respiration

artículo científico publicado en 2019

Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity

artículo científico publicado en 2013

Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance

scientific article published on 01 July 2018

Structure-guided reprogramming of human cGAS dinucleotide linkage specificity

artículo científico publicado en 2014

Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict

artículo científico publicado en 2020

The polymerase of negative-stranded RNA viruses

artículo científico publicado en 2013

Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling

scientific article published on 06 February 2019

cGAS Conducts Micronuclei DNA Surveillance

artículo científico publicado en 2017

cGAS and CD-NTase enzymes: structure, mechanism, and evolution

artículo científico publicado en 2019

cGAS dimerization entangles DNA recognition

artículo científico publicado en 2013

cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila

artículo científico publicado en 2021

eIF3 targets cell-proliferation messenger RNAs for translational activation or repression

scientific journal article

eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation

scientific journal article