Lista de obras -

A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease

artículo científico publicado en 2018

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology

artículo científico publicado en 2015

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

artículo científico publicado en 2016

A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.

artículo científico publicado en 2017

A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease

article

A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research

artículo científico publicado en 2018

A scalable online tool for quantitative social network assessment reveals potentially modifiable social environmental risks

scientific article published in Nature Communications

A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease

scientific article published on 01 August 2020

A transcriptomic atlas of aged human microglia.

artículo científico publicado en 2018

Adiponectin: an independent risk factor for coronary heart disease in men in the Framingham offspring Study

artículo científico publicado en 2011

An UNC5C Allele Predicts Cognitive Decline and Hippocampal Atrophy in Clinically Normal Older Adults.

artículo científico publicado en 2019

An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome

artículo científico publicado en 2017

Assessment of Early Evidence of Multiple Sclerosis in a Prospective Study of Asymptomatic High-Risk Family Members

artículo científico

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

artículo científico publicado en 2011

Association of Social Network Structure and Physical Function in Patients With Multiple Sclerosis

artículo científico publicado en 2020

Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

artículo científico publicado en 2014

Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue

artículo científico publicado en 2021

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

CD33 modulates TREM2: convergence of Alzheimer loci.

artículo científico publicado en 2015

Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study

artículo científico publicado en 2013

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease

artículo científico publicado en 2019

Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia

scientific article published on 01 September 2020

Direct assessment of plasma low density lipoprotein and high density lipoprotein cholesterol levels and coronary heart disease: results from the Framingham Offspring Study.

artículo científico publicado en 2010

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Evaluating more naturalistic outcome measures: A 1-year smartphone study in multiple sclerosis

artículo científico publicado en 2015

Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

artículo científico publicado en 2015

Genes and Environment in Multiple Sclerosis project: A platform to investigate multiple sclerosis risk

artículo científico publicado en 2015

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes

artículo científico publicado en 2014

Genetic evidence of assortative mating in humans

scholarly article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

artículo científico publicado en 2019

Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology

scientific article published on 08 June 2020

Genetics of coronary artery calcification among African Americans, a meta-analysis

artículo científico publicado en 2013

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

artículo científico publicado en 2015

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium

artículo científico publicado en 2016

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women

artículo científico publicado en 2012

Genome-wide association of pericardial fat identifies a unique locus for ectopic fat

artículo científico publicado en 2012

Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction

artículo científico publicado en 2011

Hormone therapy use and physical quality of life in postmenopausal women with multiple sclerosis

artículo científico publicado en 2016

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data

artículo científico publicado en 2017

Lipoprotein(a) levels, apo(a) isoform size, and coronary heart disease risk in the Framingham Offspring Study

artículo científico publicado en 2011

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

artículo científico publicado en 2017

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

artículo científico publicado en 2016

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

artículo científico publicado en 2011

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium

artículo científico publicado en 2009

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

artículo científico publicado en 2017

Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

artículo científico publicado en 2014

Small dense LDL cholesterol and coronary heart disease: results from the Framingham Offspring Study.

artículo científico publicado en 2010

Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

artículo científico publicado en 2014

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults

artículo científico publicado en 2016

The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels

artículo científico publicado en 2014

Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci

artículo científico publicado en 2016

UNC5C variants are associated with cerebral amyloid angiopathy

artículo científico publicado en 2017

Lista de obras de

A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.

A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease

A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research

A scalable online tool for quantitative social network assessment reveals potentially modifiable social environmental risks

A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease

A transcriptomic atlas of aged human microglia.

Adiponectin: an independent risk factor for coronary heart disease in men in the Framingham offspring Study

An UNC5C Allele Predicts Cognitive Decline and Hippocampal Atrophy in Clinically Normal Older Adults.

An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome

Assessment of Early Evidence of Multiple Sclerosis in a Prospective Study of Asymptomatic High-Risk Family Members

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

Association of Social Network Structure and Physical Function in Patients With Multiple Sclerosis

Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

CD33 modulates TREM2: convergence of Alzheimer loci.

Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease

Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia

Direct assessment of plasma low density lipoprotein and high density lipoprotein cholesterol levels and coronary heart disease: results from the Framingham Offspring Study.

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Evaluating more naturalistic outcome measures: A 1-year smartphone study in multiple sclerosis

Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

Genes and Environment in Multiple Sclerosis project: A platform to investigate multiple sclerosis risk

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

Genetic architecture of subcortical brain structures in 38,851 individuals

Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes

Genetic evidence of assortative mating in humans

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology

Genetics of coronary artery calcification among African Americans, a meta-analysis

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women

Genome-wide association of pericardial fat identifies a unique locus for ectopic fat

Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction

Hormone therapy use and physical quality of life in postmenopausal women with multiple sclerosis

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data

Lipoprotein(a) levels, apo(a) isoform size, and coronary heart disease risk in the Framingham Offspring Study

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

Small dense LDL cholesterol and coronary heart disease: results from the Framingham Offspring Study.

Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults

The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels

Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci

UNC5C variants are associated with cerebral amyloid angiopathy