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ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.

artículo científico publicado en 2011

ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.

artículo científico publicado en 2011

Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma.

artículo científico publicado en 2007

Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface

scientific article published on 09 September 2019

Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis.

artículo científico publicado en 2016

Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma

artículo científico publicado en 2019

Intra-tumoral copper modulates PD-L1 expression and influences tumor immune evasion

scientific article published on 18 August 2020

MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin.

artículo científico publicado en 2016

Macrophage-Derived IL1β and TNFα Regulate Arginine Metabolism in Neuroblastoma

artículo científico publicado en 2018

N-Myc regulates expression of the detoxifying enzyme glutathione transferase GSTP1, a marker of poor outcome in neuroblastoma.

artículo científico publicado en 2011

Polymorphisms in genes encoding drug metabolizing enzymes and their influence on the outcome of children with neuroblastoma

artículo científico publicado en 2007

Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors

artículo científico publicado en 2021

Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo.

artículo científico publicado en 2017