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A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin

artículo científico publicado en 2008

Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy

artículo científico publicado en 2022

Another surprise from Metformin: novel mechanism of action via K-Ras influences endometrial cancer response to therapy.

artículo científico publicado en 2013

CGRRF1 as a novel biomarker of tissue response to metformin in the context of obesity

artículo científico publicado en 2014

Chemopreventive effects of metformin on obesity-associated endometrial proliferation

scientific article published on 15 March 2013

Chemopreventive promise of targeting the Nrf2 pathway

artículo científico publicado en 2007

Endometrial Cancers With Activating KRas Mutations Have Activated Estrogen Signaling and Paradoxical Response to MEK Inhibition.

artículo científico publicado en 2017

Endometrial biomarkers in premenopausal obese women: an at-risk cohort

scientific article published on 21 August 2020

Everolimus, Letrozole, and Metformin in Women with Advanced or Recurrent Endometrioid Endometrial Cancer: A Multi-Center, Single Arm, Phase II Study

scientific article published on 18 October 2019

Fertility-sparing treatment in early endometrial cancer: current state and future strategies

artículo científico publicado en 2020

Formation of fibrinogen-based hydrogels using phototriggerable diplasmalogen liposomes

artículo científico publicado en 2002

Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice

artículo científico publicado en 2008

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice.

artículo científico publicado en 2009

Immune Microenvironment in Microsatellite-Instable Endometrial Cancers: Hereditary or Sporadic Origin Matters

artículo científico publicado en 2017

Improving response to progestin treatment of low-grade endometrial cancer

scientific article published on 06 May 2020

Isothiazolopyrimidines and isoxazolopyrimidines as novel multi-targeted inhibitors of receptor tyrosine kinases.

artículo científico publicado en 2006

Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids

artículo científico publicado en 2007

Lean Body Weight and Metformin Are Insufficient to Prevent Endometrial Hyperplasia in Mice Harboring Inactivating Mutations in PTEN.

artículo científico publicado en 2016

Lymphocyte-specific kinase expression is a prognostic indicator in ovarian cancer and correlates with a prominent B cell transcriptional signature

artículo científico publicado en 2019

Microscopic and early-stage ovarian cancers in BRCA1/2 mutation carriers: building a model for early BRCA-associated tumorigenesis

artículo científico publicado en 2011

Molecular pathogenesis of endometrial cancers in patients with Lynch syndrome

artículo científico publicado en 2013

Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide

artículo científico publicado en 2006

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.

artículo científico publicado en 2007

Phase II study of everolimus and letrozole in patients with recurrent endometrial carcinoma

artículo científico publicado en 2015

Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole

artículo científico publicado en 2006

Predicting high-risk endometrioid carcinomas using proteins.

artículo científico publicado en 2018

Prognostic and biologic significance of high LCK expression in ovarian cancer

artículo científico publicado en 2015

Prospective Phase II Trial of Levonorgestrel Intrauterine Device: Non-Surgical Approach for Complex Atypical Hyperplasia and Early Endometrial Cancer

scientific article published on 14 August 2020

Prospective Randomized Biomarker Study of Metformin and Lifestyle Intervention for Prevention in Obese Women at Increased Risk for Endometrial Cancer

Prospective evaluation of the molecular effects of metformin on the endometrium in women with newly diagnosed endometrial cancer: A window of opportunity study

artículo científico publicado en 2016

Prospective multicenter randomized intermediate biomarker study of oral contraceptive versus depo-provera for prevention of endometrial cancer in women with Lynch syndrome

artículo científico publicado en 2013

Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer

scientific article published on 27 February 2020

Pushing the envelope: expanding fertility sparing treatment of endometrial cancer

artículo científico publicado en 2020

Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide

artículo científico publicado en 2009

Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

scholarly article

The monkey, the hen, and the mouse: models to advance ovarian cancer chemoprevention

artículo científico publicado en 2009

The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice

scientific article published on 13 August 2009

Thienopyridine urea inhibitors of KDR kinase.

artículo científico publicado en 2006

Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Promotes Uterine Serous Cancer Cell Proliferation and Cell Cycle Progression

scientific article published on 02 January 2020

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