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13q14 deletion size and number of deleted cells both influence prognosis in chronic lymphocytic leukemia

artículo científico

<i>SF3B1</i>-mutated chronic lymphocytic leukemia shows evidence of NOTCH1 pathway activation including CD20 downregulation

artículo científico publicado en 2020

ARHGDIA, a mutant TP53-associated Rho GDP dissociation inhibitor, is over-expressed in gene expression profiles ofTP53disrupted chronic lymphocytic leukaemia cells

article

Association between molecular lesions and specific B-cell receptor subsets in chronic lymphocytic leukemia.

artículo científico publicado en 2013

B-cell receptor, clinical course and prognosis in chronic lymphocytic leukaemia: the growing saga of the IGHV3 subgroup gene usage

artículo científico publicado en 2011

CD49d is overexpressed by trisomy 12 chronic lymphocytic leukemia cells: evidence for a methylation-dependent regulation mechanism

article

Detection of TP53 dysfunction in chronic lymphocytic leukemia by an in vitro functional assay based on TP53 activation by the non-genotoxic drug Nutlin-3: a proposal for clinical application.

artículo científico publicado en 2013

Direct-acting antiviral agents for hepatitis C virus-mixed cryoglobulinaemia: dissociated virological and haematological responses

scientific article published on 13 August 2020

Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia

artículo científico publicado en 2018

IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia

artículo científico publicado en 2012

KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival

artículo científico publicado en 2019

MDM4 (MDMX) is overexpressed in chronic lymphocytic leukaemia (CLL) and marks a subset of p53wild-type CLL with a poor cytotoxic response to Nutlin-3.

artículo científico publicado en 2010

Merkel-cell polyomavirus (MCPyV) is rarely associated to B-chronic lymphocytic leukemia (1 out of 50) samples and occurs late in the natural history of the disease.

artículo científico publicado en 2012

Multicentre validation of a prognostic index for overall survival in chronic lymphocytic leukaemia

artículo científico publicado en 2010

Mutational status of IGHV is the most reliable prognostic marker in trisomy 12 chronic lymphocytic leukemia.

artículo científico publicado en 2017

Mutations in the 3′ untranslated region of NOTCH1 are associated with low CD20 expression levels chronic lymphocytic leukemia

scientific article published on 26 May 2017

NOTCH1 mutational status in chronic lymphocytic leukaemia: clinical relevance of subclonal mutations and mutation types.

artículo científico publicado en 2017

Polymer-Mediated Delivery of siRNAs to Hepatocellular Carcinoma: Variables Affecting Specificity and Effectiveness

scientific article published on 28 March 2018

Strategies to optimize siRNA delivery to hepatocellular carcinoma cells.

artículo científico publicado en 2017

The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells.

artículo científico publicado en 2015

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