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A broad-spectrum antiviral targeting entry of enveloped viruses

artículo científico publicado en 2010

A catalytically and genetically optimized beta-lactamase-matrix based assay for sensitive, specific, and higher throughput analysis of native henipavirus entry characteristics

artículo científico publicado en 2009

A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion

artículo científico publicado en 2013

A novel highly potent inhibitor of TMPRSS2-like proteases blocks SARS-CoV-2 variants of concern and is broadly protective against infection and mortality in mice

artículo científico publicado en 2021

A novel receptor-induced activation site in the Nipah virus attachment glycoprotein (G) involved in triggering the fusion glycoprotein (F)

artículo científico publicado en 2008

A quantitative and kinetic fusion protein-triggering assay can discern distinct steps in the nipah virus membrane fusion cascade

artículo científico publicado en 2010

A stochastic assembly model for Nipah virus revealed by super-resolution microscopy

artículo científico publicado en 2018

Addicted to sugar: roles of glycans in the order Mononegavirales

artículo científico publicado en 2019

An increase in glycoprotein concentration on extracellular virions dramatically alters vaccinia virus infectivity and pathogenesis without impacting immunogenicity

artículo científico publicado en 2021

Antibodies to ovine herpesvirus 2 glycoproteins decrease virus infectivity and prevent malignant catarrhal fever in rabbits

artículo científico publicado en 2014

A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic

artículo científico publicado en 2022

Broad-spectrum antiviral JL122 blocks infection and inhibits transmission of aquatic rhabdoviruses

Broad-spectrum antiviral JL122 blocks infection and inhibits transmission of aquatic rhabdoviruses

Contributions of herpes simplex virus 1 envelope proteins to entry by endocytosis

artículo científico publicado en 2013

Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly

artículo científico publicado en 2015

Cysteines in the stalk of the nipah virus G glycoprotein are located in a distinct subdomain critical for fusion activation

artículo científico publicado en 2012

Cytoplasmic Motifs in the Nipah Virus Fusion Protein Modulate Virus Particle Assembly and Egress

artículo científico publicado en 2017

Detection of receptor-induced glycoprotein conformational changes on enveloped virions by using confocal micro-Raman spectroscopy.

artículo científico publicado en 2013

Emerging paramyxoviruses: molecular mechanisms and antiviral strategies

artículo científico publicado en 2011

Endothelial galectin-1 binds to specific glycans on nipah virus fusion protein and inhibits maturation, mobility, and function to block syncytia formation

artículo científico publicado en 2010

EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus

artículo científico publicado en 2005

Expression of 9-O- and 7,9-O-Acetyl Modified Sialic Acid in Cells and Their Effects on Influenza Viruses

scientific article published on 03 December 2019

Feline Morbillivirus, a New Paramyxovirus Possibly Associated with Feline Kidney Disease

artículo científico publicado en 2020

Finding proteases that make cells go viral

artículo científico publicado en 2020

Flow virometry as a tool to study viruses

artículo científico publicado en 2017

Henipavirus Membrane Fusion and Viral Entry

artículo científico publicado el 1 de enero de 2012

Individual N-glycans added at intervals along the stalk of the Nipah virus G protein prevent fusion but do not block the interaction with the homologous F protein

artículo científico publicado en 2013

Inhibition of an Aquatic Rhabdovirus Demonstrates Promise of a Broad-Spectrum Antiviral for Use in Aquaculture

artículo científico publicado en 2016

Interactions of human complement with virus particles containing the Nipah virus glycoproteins

artículo científico publicado en 2011

Mildly Acidic pH Triggers an Irreversible Conformational Change in the Fusion Domain of Herpes Simplex Virus 1 Glycoprotein B and Inactivation of Viral Entry

artículo científico publicado en 2016

Modified sialic acids on mucus and erythrocytes inhibit influenza A HA and NA functions

artículo científico publicado en 2020

Molecular requirement for sterols in herpes simplex virus entry and infectivity

artículo científico publicado en 2014

Multiple Novel Functions of Henipavirus O-glycans: The First O-glycan Functions Identified in the Paramyxovirus Family

artículo científico publicado en 2016

Multiple Strategies Reveal a Bidentate Interaction between the Nipah Virus Attachment and Fusion Glycoproteins

artículo científico publicado en 2016

N-Glycans on the Nipah virus attachment glycoprotein modulate fusion and viral entry as they protect against antibody neutralization

artículo científico publicado en 2012

N-glycans on Nipah virus fusion protein protect against neutralization but reduce membrane fusion and viral entry

artículo científico publicado en 2006

Nipah Virus-Like Particle Egress Is Modulated by Cytoskeletal and Vesicular Trafficking Pathways: a Validated Particle Proteomics Analysis

scientific article published on 24 September 2019

Nipah and Hendra Virus Glycoproteins Induce Comparable Homologous but Distinct Heterologous Fusion Phenotypes

scientific article published on 14 June 2019

Nipah virion entry kinetics, composition, and conformational changes determined by enzymatic virus-like particles and new flow virometry tools

artículo científico publicado en 2014

Nipah virus attachment glycoprotein stalk C-terminal region links receptor binding to fusion triggering

artículo científico publicado en 2014

Novel Functions of Hendra Virus G N-Glycans and Comparisons to Nipah Virus

artículo científico publicado en 2015

Novel innate immune functions for galectin-1: galectin-1 inhibits cell fusion by Nipah virus envelope glycoproteins and augments dendritic cell secretion of proinflammatory cytokines

artículo científico publicado en 2005

Ovine Herpesvirus 2 Glycoproteins B, H, and L Are Sufficient for, and Viral Glycoprotein Ov8 Can Enhance, Cell-Cell Membrane Fusion.

artículo científico publicado en 2017

Paramyxovirus Glycoproteins and the Membrane Fusion Process

artículo científico publicado en 2016

Polybasic KKR motif in the cytoplasmic tail of Nipah virus fusion protein modulates membrane fusion by inside-out signaling

artículo científico publicado en 2007

Polyethylene glycol-mediated fusion of herpes simplex type 1 virions with the plasma membrane of cells that support endocytic entry

artículo científico publicado en 2015

Rho GTPase activity modulates paramyxovirus fusion protein-mediated cell–cell fusion

Roles of Cholesterol in Early and Late Steps of the Nipah Virus Membrane Fusion Cascade

scientific article published on 06 January 2021

SialoPen peptides are new cationic foldamers with remarkable cell permeability

artículo científico publicado en 2020

Single amino acid changes in the Nipah and Hendra virus attachment glycoproteins distinguish ephrinB2 from ephrinB3 usage

artículo científico publicado en 2007

The effects of modified sialic acids on mucus and erythrocytes on influenza A virus HA and NA functions

scientific article published on 10 October 2019

Third Helical Domain of the Nipah Virus Fusion Glycoprotein Modulates Both Early and Late Steps in the Membrane Fusion Cascade

scientific article published on 15 July 2020

Timing of galectin-1 exposure differentially modulates Nipah virus entry and syncytium formation in endothelial cells

artículo científico publicado en 2014

Triggering of the newcastle disease virus fusion protein by a chimeric attachment protein that binds to Nipah virus receptors

artículo científico publicado en 2011

Two key residues in ephrinB3 are critical for its use as an alternative receptor for Nipah virus

artículo científico publicado en 2006

Unraveling a three-step spatiotemporal mechanism of triggering of receptor-induced Nipah virus fusion and cell entry.

artículo científico publicado en 2013

Widely Used Herpes Simplex Virus 1 ICP0 Deletion Mutant Strain dl1403 and Its Derivative Viruses Do Not Express Glycoprotein C Due to a Secondary Mutation in the gC Gene

artículo científico publicado en 2015