Lista de obras -

A Neural "Tuning Curve" for Multisensory Experience and Cognitive-Perceptual Schizotypy.

artículo científico publicado en 2017

A conserved BDNF, glutamate- and GABA-enriched gene module related to human depression identified by coexpression meta-analysis and DNA variant genome-wide association studies

artículo científico publicado en 2014

A human-mouse conserved sex bias in amygdala gene expression related to circadian clock and energy metabolism

artículo científico publicado en 2011

A molecular signature of depression in the amygdala

artículo científico publicado en 2009

A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicide

artículo científico publicado en 2014

Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry

artículo científico publicado en 2012

Advances in bipolar disorder: selected sessions from the 2011 International Conference on Bipolar Disorder

artículo científico publicado en 2011

Age-Related Gene Expression in the Frontal Cortex Suggests Synaptic Function Changes in Specific Inhibitory Neuron Subtypes

artículo científico publicado en 2017

Age-by-disease biological interactions: implications for late-life depression.

artículo científico publicado en 2012

Age-dependent increase in Kalirin-9 and Kalirin-12 transcripts in human orbitofrontal cortex

artículo científico publicado en 2016

Altered GABA function in Major Depression

artículo científico publicado en 2014

Altered GABA-mediated information processing and cognitive dysfunctions in depression and other brain disorders

scientific article published on 28 April 2020

Altered gene synchrony suggests a combined hormone-mediated dysregulated state in major depression

artículo científico publicado en 2010

An R package suite for microarray meta-analysis in quality control, differentially expressed gene analysis and pathway enrichment detection

artículo científico publicado en 2012

Anticipated brain molecular aging in major depression

artículo científico publicado en 2013

Between destiny and disease: genetics and molecular pathways of human central nervous system aging

artículo científico publicado en 2010

Beyond genotype: serotonin transporter epigenetic modification predicts human brain function

artículo científico publicado en 2014

Biological substrates underpinning diagnosis of major depression ⬇️

artículo científico publicado el 14 de mayo de 2013

Brain molecular aging, promotion of neurological disease and modulation by Sirtuin5 longevity gene polymorphism ⬇️

artículo científico publicado el 29 de septiembre de 2010

Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder

artículo científico publicado en 2012

Cell Type-Specific Gene Expression of Alpha 5 Subunit-Containing Gamma-Aminobutyric Acid Subtype A Receptors in Human and Mouse Frontal Cortex

artículo científico publicado en 2019

Characterization of GABAergic marker expression in the chronic unpredictable stress model of depression

artículo científico publicado en 2017

Chronic stress-induced behaviors correlate with exacerbated acute stress-induced cingulate cortex and ventral hippocampus activation

artículo científico publicado en 2020

Circulating biosignatures of late-life depression (LLD): Towards a comprehensive, data-driven approach to understanding LLD pathophysiology

artículo científico publicado en 2016

Correction: Human Induced Pluripotent Stem Cell-Derived Models to Investigate Human Cytomegalovirus Infection in Neural Cells.

artículo científico publicado en 2014

Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice.

artículo científico publicado en 2006

Corticolimbic transcriptome changes are state-dependent and region-specific in a rodent model of depression and of antidepressant reversal

scientific article published on 04 June 2008

Cross-Laboratory Analysis of Brain Cell Type Transcriptomes with Applications to Interpretation of Bulk Tissue Data

artículo científico publicado en 2017

DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions

artículo científico publicado en 2019

Decrease in somatostatin-positive cell density in the amygdala of females with major depression

artículo científico publicado en 2016

Detecting disease-associated genes with confounding variable adjustment and the impact on genomic meta-analysis: With application to major depressive disorder ⬇️

artículo científico publicado el 29 de marzo de 2012

Differential and spatial expression meta-analysis of genes identified in genome-wide association studies of depression

artículo científico publicado en 2021

Differentially Expressed Genes in Major Depression Reside on the Periphery of Resilient Gene Coexpression Networks ⬇️

artículo científico publicado el 30 de agosto de 2011

Effects of aging on circadian patterns of gene expression in the human prefrontal cortex

artículo científico publicado en 2015

Elevated Hippocampal Cholinergic Neurostimulating Peptide precursor protein (HCNP-pp) mRNA in the amygdala in major depression.

artículo científico publicado en 2015

Enhanced Molecular Aging in Late-Life Depression: the Senescent-Associated Secretory Phenotype

artículo científico publicado en 2016

FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk

artículo científico publicado en 2015

Fluorescence-based cell-specific detection for laser-capture microdissection in human brain

artículo científico publicado en 2017

GABA-related transcripts in the dorsolateral prefrontal cortex in mood disorders

artículo científico publicado en 2011

Gene expression profiling of depression and suicide in human prefrontal cortex

artículo científico publicado en 2004

Human induced pluripotent stem cell-derived models to investigate human cytomegalovirus infection in neural cells

artículo científico publicado en 2012

Hypermethylation of BDNF and SST Genes in the Orbital Frontal Cortex of Older Individuals: A Putative Mechanism for Declining Gene Expression with Age.

artículo científico publicado en 2015

Identification of a novel gene regulating amygdala-mediated fear extinction.

artículo científico publicado en 2018

Imputation of Truncated p-Values For Meta-Analysis Methods and Its Genomic Application ⬇️

artículo científico publicado en 2014

Increased Neuronal DNA/RNA Oxidation in the Frontal Cortex of Mice Subjected to Unpredictable Chronic Mild Stress

artículo científico publicado en 2017

Insight into Novel Treatment for Cognitive Dysfunctions across Disorders

scientific article published on 28 March 2019

Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: relevance to emotionality and sex

artículo científico publicado en 2011

Laminar and cellular analyses of reduced somatostatin gene expression in the subgenual anterior cingulate cortex in major depression

artículo científico publicado en 2014

Large-scale estimates of cellular origins of mRNAs: enhancing the yield of transcriptome analyses

artículo científico publicado en 2007

Major depression and enhanced molecular senescence abnormalities in young and middle-aged adults

artículo científico publicado en 2019

Meta-analysis methods for combining multiple expression profiles: comparisons, statistical characterization and an application guideline

artículo científico publicado en 2013

MetaOmics: Analysis Pipeline and Browser-based Software Suite for Transcriptomic Meta-Analysis

article

MetaQC: objective quality control and inclusion/exclusion criteria for genomic meta-analysis

artículo científico publicado en 2011

Molecular aging in human prefrontal cortex is selective and continuous throughout adult life

artículo científico publicado en 2005

Molecular aging of the brain, neuroplasticity, and vulnerability to depression and other brain-related disorders ⬇️

artículo científico publicado el 1 de marzo de 2013

Molecular and Cellular Evidence for Age by Disease Interactions: Updates and Path Forward

scientific article published on 12 June 2019

Molecular and Genetic Characterization of Depression: Overlap with other Psychiatric Disorders and Aging

artículo científico publicado en 2015

Molecular characterization of depression trait and state

artículo científico publicado en 2021

Neonatal testosterone partially organizes sex differences in stress-induced emotionality in mice

artículo científico publicado en 2012

Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: major depression and suicide

artículo científico publicado en 2006

No interaction between polygenic scores and childhood trauma in predicting suicide attempt in schizophrenia

artículo científico publicado en 2018

Norepinephrine Transporter Gene Variants and Remission From Depression With Venlafaxine Treatment in Older Adults

artículo científico publicado en 2017

Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles

scientific article published on 23 January 2019

Novel polygenic risk score as a translational tool linking depression-related changes in the corticolimbic transcriptome with neural face processing and anhedonic symptoms

artículo científico publicado en 2020

Older molecular brain age in severe mental illness

artículo científico publicado en 2020

Opposing effects of acute versus chronic blockade of frontal cortex somatostatin-positive inhibitory neurons on behavioral emotionality in mice

artículo científico publicado en 2014

Opposite Molecular Signatures of Depression in Men and Women

artículo científico publicado en 2018

Potential combined pro-cognitive, anxiolytic and antidepressant properties of novel GABAA receptor positive modulators with preferential efficacy at the α5-subunit

Predisposition to treatment response in major depressive episode: A peripheral blood gene coexpression network analysis.

artículo científico

Reciprocal phylogenetic conservation of molecular aging in mouse and human brain

artículo científico publicado en 2009

Reduced GABAergic cortical inhibition in aging and depression

scholarly article by Jennifer I Lissemore et al published October 2018 in Neuropsychopharmacology

Reduced Somatostatin Expression or Somatostatin-Positive Gamma-Aminobutyric Acid Neurons: A Shared Pathology Across Brain Disorders

artículo científico publicado en 2017

Reduced brain somatostatin in mood disorders: a common pathophysiological substrate and drug target? ⬇️

artículo científico publicado el 9 de septiembre de 2013

Reduced somatostatin in subgenual anterior cingulate cortex in major depression

artículo científico publicado en 2011

Residual avoidance: A new, consistent and repeatable readout of chronic stress-induced conflict anxiety reversible by antidepressant treatment

scientific article published on 08 May 2019

Resilient protein co-expression network in male orbitofrontal cortex layer 2/3 during human aging

artículo científico publicado en 2017

Reversal of Age-Related Neuronal Atrophy by α5-GABAA Receptor Positive Allosteric Modulation

artículo científico publicado en 2020

SERT-ainly involved in depression, but when?

artículo científico publicado en 2006

Sex chromosome complement regulates expression of mood-related genes.

artículo científico publicado en 2013

Sex differences in mood disorders: perspectives from humans and rodent models

artículo científico publicado en 2014

Sex genes for genomic analysis in human brain: internal controls for comparison of probe level data extraction

artículo científico publicado en 2003

Sex-Dependent Anti-Stress Effect of an α5 Subunit Containing GABAA Receptor Positive Allosteric Modulator.

artículo científico publicado en 2016

Shifting priorities: highly conserved behavioral and brain network adaptations to chronic stress across species.

artículo científico publicado en 2018

Sigma-1 and N-Methyl-d-Aspartate Receptors: A Partnership with Beneficial Outcomes

artículo científico publicado en 2015

Sleep-dependent gene expression in the hippocampus and prefrontal cortex following long-term potentiation

artículo científico publicado en 2009

Somatostatin-Positive Gamma-Aminobutyric Acid Interneuron Deficits in Depression: Cortical Microcircuit and Therapeutic Perspectives

artículo científico publicado en 2017

Sustained Molecular Pathology Across Episodes and Remission in Major Depressive Disorder

artículo científico publicado en 2017

Synaptic underpinnings of altered hippocampal function in glutaminase-deficient mice during maturation

artículo científico publicado en 2012

Synthesis of chiral GABAA receptor subtype selective ligands as potential agents to treat schizophrenia as well as depression

scientific article published on 11 March 2018

Testing the predictive value of peripheral gene expression for nonremission following citalopram treatment for major depression

artículo científico publicado en 2014

The RNA binding domain of Jerky consists of tandemly arranged helix-turn-helix/homeodomain-like motifs and binds specific sets of mRNAs

artículo científico publicado en 2003

The Relative Contributions of Cell-Dependent Cortical Microcircuit Aging to Cognition and Anxiety

scientific article published on 05 October 2018

The Role of BDNF in Age-Dependent Changes of Excitatory and Inhibitory Synaptic Markers in the Human Prefrontal Cortex

artículo científico publicado en 2016

The Role of Dendritic Brain-Derived Neurotrophic Factor Transcripts on Altered Inhibitory Circuitry in Depression

scientific article published on 09 October 2018

The Role of Genetic Sex in Affect Regulation and Expression of GABA-Related Genes Across Species

artículo científico publicado en 2013

The age-by-disease interaction hypothesis of late-life depression.

artículo científico publicado en 2013

The roles of sex and serotonin transporter levels in age- and stress-related emotionality in mice

artículo científico publicado en 2009

Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons

artículo científico publicado en 2018

Using the gene ontology for microarray data mining: a comparison of methods and application to age effects in human prefrontal cortex

artículo científico publicado en 2004

Why are cortical GABA neurons relevant to internal focus in depression? A cross-level model linking cellular, biochemical and neural network findings

artículo científico publicado en 2014

Will Neurobiology Rise to the Translational Challenges and Opportunities of Late-Life Geriatric Psychiatry? ⬇️

artículo científico publicado el 1 de mayo de 2013

α5GABAA receptor deficiency causes autism-like behaviors

artículo científico publicado en 2016

Lista de obras de

A Neural "Tuning Curve" for Multisensory Experience and Cognitive-Perceptual Schizotypy.

A conserved BDNF, glutamate- and GABA-enriched gene module related to human depression identified by coexpression meta-analysis and DNA variant genome-wide association studies

A human-mouse conserved sex bias in amygdala gene expression related to circadian clock and energy metabolism

A molecular signature of depression in the amygdala

A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicide

Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry

Advances in bipolar disorder: selected sessions from the 2011 International Conference on Bipolar Disorder

Age-Related Gene Expression in the Frontal Cortex Suggests Synaptic Function Changes in Specific Inhibitory Neuron Subtypes

Age-by-disease biological interactions: implications for late-life depression.

Age-dependent increase in Kalirin-9 and Kalirin-12 transcripts in human orbitofrontal cortex

Altered GABA function in Major Depression

Altered GABA-mediated information processing and cognitive dysfunctions in depression and other brain disorders

Altered gene synchrony suggests a combined hormone-mediated dysregulated state in major depression

An R package suite for microarray meta-analysis in quality control, differentially expressed gene analysis and pathway enrichment detection

Anticipated brain molecular aging in major depression

Between destiny and disease: genetics and molecular pathways of human central nervous system aging

Beyond genotype: serotonin transporter epigenetic modification predicts human brain function

Biological substrates underpinning diagnosis of major depression ⬇️

Brain molecular aging, promotion of neurological disease and modulation by Sirtuin5 longevity gene polymorphism ⬇️

Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder

Cell Type-Specific Gene Expression of Alpha 5 Subunit-Containing Gamma-Aminobutyric Acid Subtype A Receptors in Human and Mouse Frontal Cortex

Characterization of GABAergic marker expression in the chronic unpredictable stress model of depression

Chronic stress-induced behaviors correlate with exacerbated acute stress-induced cingulate cortex and ventral hippocampus activation

Circulating biosignatures of late-life depression (LLD): Towards a comprehensive, data-driven approach to understanding LLD pathophysiology

Correction: Human Induced Pluripotent Stem Cell-Derived Models to Investigate Human Cytomegalovirus Infection in Neural Cells.

Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice.

Corticolimbic transcriptome changes are state-dependent and region-specific in a rodent model of depression and of antidepressant reversal

Cross-Laboratory Analysis of Brain Cell Type Transcriptomes with Applications to Interpretation of Bulk Tissue Data

DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions

Decrease in somatostatin-positive cell density in the amygdala of females with major depression

Detecting disease-associated genes with confounding variable adjustment and the impact on genomic meta-analysis: With application to major depressive disorder ⬇️

Differential and spatial expression meta-analysis of genes identified in genome-wide association studies of depression

Differentially Expressed Genes in Major Depression Reside on the Periphery of Resilient Gene Coexpression Networks ⬇️

Effects of aging on circadian patterns of gene expression in the human prefrontal cortex

Elevated Hippocampal Cholinergic Neurostimulating Peptide precursor protein (HCNP-pp) mRNA in the amygdala in major depression.

Enhanced Molecular Aging in Late-Life Depression: the Senescent-Associated Secretory Phenotype

FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk

Fluorescence-based cell-specific detection for laser-capture microdissection in human brain

GABA-related transcripts in the dorsolateral prefrontal cortex in mood disorders

Gene expression profiling of depression and suicide in human prefrontal cortex

Human induced pluripotent stem cell-derived models to investigate human cytomegalovirus infection in neural cells

Hypermethylation of BDNF and SST Genes in the Orbital Frontal Cortex of Older Individuals: A Putative Mechanism for Declining Gene Expression with Age.

Identification of a novel gene regulating amygdala-mediated fear extinction.

Imputation of Truncated p-Values For Meta-Analysis Methods and Its Genomic Application ⬇️

Increased Neuronal DNA/RNA Oxidation in the Frontal Cortex of Mice Subjected to Unpredictable Chronic Mild Stress

Insight into Novel Treatment for Cognitive Dysfunctions across Disorders

Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: relevance to emotionality and sex

Laminar and cellular analyses of reduced somatostatin gene expression in the subgenual anterior cingulate cortex in major depression

Large-scale estimates of cellular origins of mRNAs: enhancing the yield of transcriptome analyses

Major depression and enhanced molecular senescence abnormalities in young and middle-aged adults

Meta-analysis methods for combining multiple expression profiles: comparisons, statistical characterization and an application guideline

MetaOmics: Analysis Pipeline and Browser-based Software Suite for Transcriptomic Meta-Analysis

MetaQC: objective quality control and inclusion/exclusion criteria for genomic meta-analysis

Molecular aging in human prefrontal cortex is selective and continuous throughout adult life

Molecular aging of the brain, neuroplasticity, and vulnerability to depression and other brain-related disorders ⬇️

Molecular and Cellular Evidence for Age by Disease Interactions: Updates and Path Forward

Molecular and Genetic Characterization of Depression: Overlap with other Psychiatric Disorders and Aging

Molecular characterization of depression trait and state

Neonatal testosterone partially organizes sex differences in stress-induced emotionality in mice

Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: major depression and suicide

No interaction between polygenic scores and childhood trauma in predicting suicide attempt in schizophrenia

Norepinephrine Transporter Gene Variants and Remission From Depression With Venlafaxine Treatment in Older Adults

Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles

Novel polygenic risk score as a translational tool linking depression-related changes in the corticolimbic transcriptome with neural face processing and anhedonic symptoms

Older molecular brain age in severe mental illness

Opposing effects of acute versus chronic blockade of frontal cortex somatostatin-positive inhibitory neurons on behavioral emotionality in mice

Opposite Molecular Signatures of Depression in Men and Women

Potential combined pro-cognitive, anxiolytic and antidepressant properties of novel GABAA receptor positive modulators with preferential efficacy at the α5-subunit

Predisposition to treatment response in major depressive episode: A peripheral blood gene coexpression network analysis.

Reciprocal phylogenetic conservation of molecular aging in mouse and human brain

Reduced GABAergic cortical inhibition in aging and depression

Reduced Somatostatin Expression or Somatostatin-Positive Gamma-Aminobutyric Acid Neurons: A Shared Pathology Across Brain Disorders

Reduced brain somatostatin in mood disorders: a common pathophysiological substrate and drug target? ⬇️

Reduced somatostatin in subgenual anterior cingulate cortex in major depression

Residual avoidance: A new, consistent and repeatable readout of chronic stress-induced conflict anxiety reversible by antidepressant treatment

Resilient protein co-expression network in male orbitofrontal cortex layer 2/3 during human aging

Reversal of Age-Related Neuronal Atrophy by α5-GABAA Receptor Positive Allosteric Modulation

SERT-ainly involved in depression, but when?

Sex chromosome complement regulates expression of mood-related genes.