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Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture

artículo científico publicado en 2017

Activation of interferon-stimulated response element in huh-7 cells replicating hepatitis C virus subgenomic RNA.

artículo científico publicado en 2005

Active glycolytic metabolism in CD133(+) hepatocellular cancer stem cells: regulation by MIR-122.

artículo científico publicado en 2015

Adenovirus induced acute hepatitis in non-human primates after liver-directed gene therapy.

artículo científico publicado en 2002

Adult Hepatocytes Are Hedgehog-Responsive Cells in the Setting of Liver Injury: Evidence for Smoothened-Mediated Activation of NF-κB/Epidermal Growth Factor Receptor/Akt in Hepatocytes that Counteract Fas-Induced Apoptosis

artículo científico publicado en 2018

Alpha interferon inhibits translation mediated by the internal ribosome entry site of six different hepatitis C virus genotypes

artículo científico publicado en 2005

Amphiphilic Polypeptoids Rupture Vesicle Bilayers To Form Peptoid-Lipid Fragments Effective in Enhancing Hydrophobic Drug Delivery

artículo científico publicado en 2019

Aptamer-functionalized Hybrid Nanoparticles to Enhance the Delivery of Doxorubicin into Breast Cancer Cells by Silencing P-glycoprotein

artículo científico publicado en 2020

Aptamer-functionalized hybrid nanoparticle for the treatment of breast cancer

artículo científico publicado en 2017

Autophagy in hepatocellular carcinomas: from pathophysiology to therapeutic response

artículo científico publicado en 2016

Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression.

artículo científico publicado en 2016

Cellular delivery of PEGylated PLGA nanoparticles

artículo científico publicado en 2011

Chaperone-Mediated Autophagy Promotes Beclin1 Degradation in Persistently Infected Hepatitis C Virus Cell Culture

Chaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture

artículo científico publicado en 2015

Chaperone-Mediated Autophagy in the Liver: Good or Bad?

scientific article published on 24 October 2019

Chaperone-mediated autophagy compensates for impaired macroautophagy in the cirrhotic liver to promote hepatocellular carcinoma

artículo científico publicado en 2017

Combined Treatment of Tyrosine Kinase Inhibitor-Labeled Gold Nanorod Encapsulated Albumin With Laser Thermal Ablation in a Renal Cell Carcinoma Model

artículo científico publicado en 2016

Comparison of sorafenib-loaded poly (lactic/glycolic) acid and DPPC liposome nanoparticles in the in vitro treatment of renal cell carcinoma

artículo científico publicado en 2015

Construction and characterization of an intracellular single-chain human antibody to hepatitis C virus non-structural 3 protein

artículo científico publicado en 2002

Correction: SH2 Modified STAT1 Induces HLA-I Expression and Improves IFN-γ Signaling in IFN-α Resistant HCV Replicon Cells.

artículo científico publicado en 2010

Development and optimization of nanosomal formulations for siRNA delivery to the liver

artículo científico publicado el 18 de noviembre de 2011

Development of nanosomes using high-pressure homogenization for gene therapy

artículo científico publicado en 2010

ENT1 and treatment of viral diseases

artículo científico publicado en 2015

Epigenetic regulation of MicroRNA-122 by peroxisome proliferator activated receptor-gamma and hepatitis b virus X protein in hepatocellular carcinoma cells

artículo científico publicado el 17 de septiembre de 2013

Epstein-Barr virus and human hepatocellular carcinoma

artículo científico publicado en 2003

Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture

artículo científico publicado el 3 de agosto de 2012

Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma

artículo científico publicado en 2016

HCV infection selectively impairs type I but not type III IFN signaling

artículo científico publicado en 2013

HCV-hepatocellular carcinoma: new findings and hope for effective treatment

artículo científico publicado en 2005

Hepatic Stress Response in HCV Infection Promotes STAT3-Mediated Inhibition of HNF4A-miR-122 Feedback Loop in Liver Fibrosis and Cancer Progression

scientific article published on 20 September 2019

Hepatitis C Virus Infection Induces Autophagy as a Prosurvival Mechanism to Alleviate Hepatic ER-Stress Response

artículo científico publicado en 2016

Hepatitis C virus infection impairs IRF-7 translocation and Alpha interferon synthesis in immortalized human hepatocytes

artículo científico publicado en 2010

Hepatocellular Carcinoma Mechanisms Associated with Chronic HCV Infection and the Impact of Direct-Acting Antiviral Treatment

scientific article published on 15 April 2020

Hepatocellular carcinoma xenograft supports HCV replication: a mouse model for evaluating antivirals

artículo científico publicado en 2011

Hybrid paclitaxel and gold nanorod-loaded human serum albumin nanoparticles for simultaneous chemotherapeutic and photothermal therapy on 4T1 breast cancer cells

artículo científico publicado en 2015

IFN-λ Inhibits MiR-122 Transcription through a Stat3-HNF4α Inflammatory Feedback Loop in an IFN-α Resistant HCV Cell Culture System

artículo científico publicado en 2015

Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway

artículo científico publicado en 2010

Impaired autophagy response in human hepatocellular carcinoma.

artículo científico

Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis

artículo científico publicado en 2014

In vivo anticancer synergy mechanism of doxorubicin and verapamil combination treatment is impaired in BALB/c mice with metastatic breast cancer.

artículo científico publicado en 2014

Increased expression of P-glycoprotein and doxorubicin chemoresistance of metastatic breast cancer is regulated by miR-298.

artículo científico publicado en 2012

Increased expression of P-glycoprotein is associated with doxorubicin chemoresistance in the metastatic 4T1 breast cancer model

artículo científico publicado en 2011

Inhibition of Hepatitis C Virus Nonstructural Protein, Helicase Activity, and Viral Replication by a Recombinant Human Antibody Clone

artículo científico publicado en 2004

Inhibition of hedgehog signaling ameliorates hepatic inflammation in mice with nonalcoholic fatty liver disease

artículo científico publicado en 2015

Integrated stress response in hepatitis C promotes Nrf2-related chaperone-mediated autophagy: A novel mechanism for host-microbe survival and HCC development in liver cirrhosis

scientific article published on 08 August 2019

Integrin subunits alpha5 and alpha6 regulate cell cycle by modulating the chk1 and Rb/E2F pathways to affect breast cancer metastasis

artículo científico publicado en 2011

Interferon alpha induced intrahepatic pSTAT1 inversely correlate with serum HCV RNA levels in chronic HCV infection

artículo científico publicado en 2013

Interferon alpha-2b inhibits negative-strand RNA and protein expression from full-length HCV1a infectious clone

artículo científico publicado en 2004

Interferon and ribavirin combination treatment synergistically inhibit HCV internal ribosome entry site mediated translation at the level of polyribosome formation

artículo científico publicado en 2013

Interferon-alpha-induced hepatitis C virus clearance restores p53 tumor suppressor more than direct-acting antivirals

artículo científico publicado en 2017

Interferons alpha, beta, gamma each inhibit hepatitis C virus replication at the level of internal ribosome entry site-mediated translation

artículo científico publicado en 2005

Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication

artículo científico publicado en 2010

Intracytoplasmic stable expression of IgG1 antibody targeting NS3 helicase inhibits replication of highly efficient hepatitis C Virus 2a clone.

artículo científico publicado en 2010

Langerhans cell histiocytosis: report of a single organ involvement in a child

artículo científico publicado en 2004

Linking chronic wasting disease to scrapie by comparison of Spiroplasma mirum ribosomal DNA sequences

artículo científico publicado en 2004

Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1.

artículo científico publicado en 2011

Persistent hepatitis C virus infection impairs ribavirin antiviral activity through clathrin-mediated trafficking of equilibrative nucleoside transporter 1.

artículo científico publicado en 2014

Preparation and in-vitro/in-vivo evaluation of surface-modified poly (lactide-co-glycolide) fluorescent nanoparticles

artículo científico publicado en 2010

Proteomics computational analyses suggest that hepatitis C virus E1 and pestivirus E2 envelope glycoproteins are truncated class II fusion proteins

artículo científico publicado en 2003

RETRACTED: Inhibition of Hepatitis C Virus Replication by Intracellular Delivery of Multiple siRNAs by Nanosomes

artículo científico publicado el 22 de mayo de 2012

Reduced expression of Jak-1 and Tyk-2 proteins leads to interferon resistance in Hepatitis C virus replicon

artículo científico publicado en 2007

SH2 modified STAT1 induces HLA-I expression and improves IFN-γ signaling in IFN-α resistant HCV replicon cells

artículo científico publicado en 2010

Safe method for isolation of prion protein and diagnosis of Creutzfeldt-Jakob disease.

artículo científico publicado en 2005

Small interfering RNA effectively inhibits protein expression and negative strand RNA synthesis from a full-length hepatitis C virus clone

artículo científico publicado en 2005

Small interfering RNA targeted to stem-loop II of the 5' untranslated region effectively inhibits expression of six HCV genotypes

artículo científico publicado en 2006

Stability of lyophilized siRNA nanosome formulations

artículo científico publicado en 2011

Unexpected structural features of the hepatitis C virus envelope protein 2 ectodomain.

artículo científico publicado en 2014

Yes-Associated Protein in Kupffer Cells Enhances the Production of Proinflammatory Cytokines and Promotes the Development of Nonalcoholic Steatohepatitis

artículo científico publicado en 2019

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016