Lista de obras -

A complex of EpCAM, claudin-7, CD44 variant isoforms, and tetraspanins promotes colorectal cancer progression

artículo científico publicado en 2007

A novel method for measuring cellular antibody uptake using imaging flow cytometry reveals distinct uptake rates for two different monoclonal antibodies targeting L1.

artículo científico publicado en 2015

A photosensitizer delivered by bispecific antibody redirected T lymphocytes enhances cytotoxicity against EpCAM-expressing carcinoma cells upon light irradiation.

artículo científico publicado en 2014

A standardized staining protocol for L1CAM on formalin-fixed, paraffin-embedded tissues using automated platforms

scientific article published on 25 June 2014

A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins

scientific article published on 01 June 2007

AID expression identifies interfollicular large B cells as putative precursors of mature B-cell malignancies.

artículo científico publicado en 2005

Acinar cell carcinomas of the pancreas: a molecular analysis in a series of 57 cases

artículo científico publicado en 2014

Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.

artículo científico publicado en 2014

CD133 is indicative for a resistance phenotype but does not represent a prognostic marker for survival of non-small cell lung cancer patients

artículo científico publicado en 2010

CD24 Ala57Val polymorphism predicts pathologic complete response to sequential anthracycline- and taxane-based neoadjuvant chemotherapy for primary breast cancer

artículo científico publicado en 2011

CD24 controls Src/STAT3 activity in human tumors.

artículo científico publicado en 2012

Cancer stem cell marker expression in hepatocellular carcinoma and liver metastases is not sufficient as single prognostic parameter

scientific article published on 20 November 2008

Clever-1/Stabilin-1 regulates lymphocyte migration within lymphatics and leukocyte entrance to sites of inflammation

artículo científico publicado en 2009

Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma ⬇️

artículo científico publicado el 27 de diciembre de 2011

Combining forces to hit cancer stem cells: TRAIL-lymphocytes and EpCAMxCD3 bispecific antibody show efficacy against pancreatic cancer

artículo científico publicado en 2012

Cytokine-induced killer cells against autologous CLL: direct cytotoxic effects and induction of immune accessory molecules by interferon-gamma

artículo científico publicado en 2006

Cytokine-induced killer cells targeted by the novel bispecific antibody CD19xCD5 (HD37xT5.16) efficiently lyse B-lymphoma cells

artículo científico publicado en 2007

Detection of circulating tumor-associated antigen depends on the domains recognized by the monoclonal antibodies used: N-terminal trimmed EpCAM-levels are much higher than untrimmed forms.

artículo científico publicado en 2012

Dickkopf-3, a tissue-derived modulator of local T-cell responses

artículo científico publicado en 2015

Dickkopf-3, an immune modulator in peripheral CD8 T-cell tolerance ⬇️

artículo científico publicado el 17 de enero de 2012

Dietary polyphenol quercetin targets pancreatic cancer stem cells ⬇️

artículo científico publicado el 1 de septiembre de 2010

Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells

artículo científico publicado en 2013

Effect of domain order on the activity of bacterially produced bispecific single-chain Fv antibodies.

artículo científico publicado en 2003

Effect of tetravalent bispecific CD19xCD3 recombinant antibody construct and CD28 costimulation on lysis of malignant B cells from patients with chronic lymphocytic leukemia by autologous T cells

artículo científico publicado en 2004

Efficient carcinoma cell killing by activated polymorphonuclear neutrophils targeted with an Ep-CAMxCD64 (HEA125x197) bispecific antibody

artículo científico publicado en 2002

Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment

artículo científico publicado en 2006

Elevated L1CAM expression in precursor lesions and primary and metastastic tissues of pancreatic ductal adenocarcinoma ⬇️

artículo científico publicado el 1 de octubre de 2010

Endocytosis of advanced glycation end-products in bovine choriocapillaris endothelial cells

artículo científico publicado en 2009

Expression of L1CAM, COX-2, EGFR, c-KIT and Her2/neu in anaplastic pancreatic cancer: putative therapeutic targets?

artículo científico publicado en 2010

Expression profile analysis in multiple human tumors identifies L1 (CD171) as a molecular marker for differential diagnosis and targeted therapy

artículo científico publicado en 2006

Functional analysis of bispecific antibody (EpCAMxCD3)-mediated T-lymphocyte and cancer cell interaction by single-cell force spectroscopy

artículo científico publicado en 2011

Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential

artículo científico publicado en 2014

High-density Peptide Arrays Help to Identify Linear Immunogenic B-cell Epitopes in Individuals Naturally Exposed to Malaria Infection

artículo científico publicado en 2019

Humoral response to catumaxomab correlates with clinical outcome: results of the pivotal phase II/III study in patients with malignant ascites

artículo científico publicado en 2011

Hypoxia Induces EMT in Low and Highly Aggressive Pancreatic Tumor Cells but Only Cells with Cancer Stem Cell Characteristics Acquire Pronounced Migratory Potential ⬇️

artículo científico publicado el 26 de septiembre de 2012

Immunosuppressive properties of anti-CD3 single-chain Fv and diabody

artículo científico publicado en 2004

Immunotherapy of B-cell non-Hodgkin lymphoma by targeting the chemokine receptor CXCR5 in a preclinical mouse model

artículo científico publicado en 2014

In vitro characterization of (177)Lu-radiolabelled chimeric anti-CD20 monoclonal antibody and a preliminary dosimetry study

artículo científico publicado en 2009

Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma

artículo científico publicado en 2002

L1 cell adhesion molecule as a potential therapeutic target in murine models of endometriosis using a monoclonal antibody approach

artículo científico publicado en 2013

Lack of CD24 expression in mice reduces the number of leukocytes in the colon

artículo científico publicado en 2014

Loss of Drop1 expression already at early tumor stages in a wide range of human carcinomas

artículo científico publicado en 2008

Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage

artículo científico publicado en 2011

Metalloprotease-mediated tumor cell shedding of B7-H6, the ligand of the natural killer cell-activating receptor NKp30.

artículo científico publicado en 2014

Molecular and clinical dissection of CD24 antibody specificity by a comprehensive comparative analysis

artículo científico publicado en 2010

Myofibroblast-induced tumorigenicity of pancreatic ductal epithelial cells is L1CAM dependent ⬇️

artículo científico publicado el 17 de noviembre de 2011

Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms

artículo científico publicado en 2014

New Gene-Immunotherapy Combining TRAIL-Lymphocytes and EpCAMxCD3 Bispecific Antibody for Tumor Targeting ⬇️

artículo científico publicado el 6 de enero de 2012

Quality of recombinant protein determines the amount of autoreactivity detected against the tumor-associated epithelial cell adhesion molecule antigen: low frequency of antibodies against the natural protein.

artículo científico publicado en 2005

Self-Antigen Presentation by Keratinocytes in the Inflamed Adult Skin Modulates T-Cell Auto-Reactivity

artículo científico publicado en 2015

Sulforaphane Increases Drug-mediated Cytotoxicity Toward Cancer Stem-like Cells of Pancreas and Prostate ⬇️

artículo científico publicado el 12 de octubre de 2010

Synergistic antitumor effect of bispecific CD19 x CD3 and CD19 x CD16 diabodies in a preclinical model of non-Hodgkin's lymphoma

artículo científico publicado en 2002

Systematic comparison of surface coatings for protein microarrays

scholarly article by Birgit Guilleaume published in December 2005

Target sequence accessibility limits activation-induced cytidine deaminase activity in primary mediastinal B-cell lymphoma

artículo científico publicado en 2007

Targeting of cancer stem cell marker EpCAM by bispecific antibody EpCAMxCD3 inhibits pancreatic carcinoma

artículo científico publicado en 2009

The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7

artículo científico publicado en 2005

Therapeutic Potential of Amanitin-Conjugated Anti-Epithelial Cell Adhesion Molecule Monoclonal Antibody Against Pancreatic Carcinoma ⬇️

artículo científico publicado el 27 de marzo de 2012

Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma.

artículo científico publicado en 2010

Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis

artículo científico publicado en 2016

Lista de obras de

A complex of EpCAM, claudin-7, CD44 variant isoforms, and tetraspanins promotes colorectal cancer progression

A novel method for measuring cellular antibody uptake using imaging flow cytometry reveals distinct uptake rates for two different monoclonal antibodies targeting L1.

A photosensitizer delivered by bispecific antibody redirected T lymphocytes enhances cytotoxicity against EpCAM-expressing carcinoma cells upon light irradiation.

A standardized staining protocol for L1CAM on formalin-fixed, paraffin-embedded tissues using automated platforms

A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins

AID expression identifies interfollicular large B cells as putative precursors of mature B-cell malignancies.

Acinar cell carcinomas of the pancreas: a molecular analysis in a series of 57 cases

Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.

CD133 is indicative for a resistance phenotype but does not represent a prognostic marker for survival of non-small cell lung cancer patients

CD24 Ala57Val polymorphism predicts pathologic complete response to sequential anthracycline- and taxane-based neoadjuvant chemotherapy for primary breast cancer

CD24 controls Src/STAT3 activity in human tumors.

Cancer stem cell marker expression in hepatocellular carcinoma and liver metastases is not sufficient as single prognostic parameter

Clever-1/Stabilin-1 regulates lymphocyte migration within lymphatics and leukocyte entrance to sites of inflammation

Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma ⬇️

Combining forces to hit cancer stem cells: TRAIL-lymphocytes and EpCAMxCD3 bispecific antibody show efficacy against pancreatic cancer

Cytokine-induced killer cells against autologous CLL: direct cytotoxic effects and induction of immune accessory molecules by interferon-gamma

Cytokine-induced killer cells targeted by the novel bispecific antibody CD19xCD5 (HD37xT5.16) efficiently lyse B-lymphoma cells

Detection of circulating tumor-associated antigen depends on the domains recognized by the monoclonal antibodies used: N-terminal trimmed EpCAM-levels are much higher than untrimmed forms.

Dickkopf-3, a tissue-derived modulator of local T-cell responses

Dickkopf-3, an immune modulator in peripheral CD8 T-cell tolerance ⬇️

Dietary polyphenol quercetin targets pancreatic cancer stem cells ⬇️

Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells

Effect of domain order on the activity of bacterially produced bispecific single-chain Fv antibodies.

Effect of tetravalent bispecific CD19xCD3 recombinant antibody construct and CD28 costimulation on lysis of malignant B cells from patients with chronic lymphocytic leukemia by autologous T cells

Efficient carcinoma cell killing by activated polymorphonuclear neutrophils targeted with an Ep-CAMxCD64 (HEA125x197) bispecific antibody

Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment

Elevated L1CAM expression in precursor lesions and primary and metastastic tissues of pancreatic ductal adenocarcinoma ⬇️

Endocytosis of advanced glycation end-products in bovine choriocapillaris endothelial cells

Expression of L1CAM, COX-2, EGFR, c-KIT and Her2/neu in anaplastic pancreatic cancer: putative therapeutic targets?

Expression profile analysis in multiple human tumors identifies L1 (CD171) as a molecular marker for differential diagnosis and targeted therapy

Functional analysis of bispecific antibody (EpCAMxCD3)-mediated T-lymphocyte and cancer cell interaction by single-cell force spectroscopy

Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential

High-density Peptide Arrays Help to Identify Linear Immunogenic B-cell Epitopes in Individuals Naturally Exposed to Malaria Infection

Humoral response to catumaxomab correlates with clinical outcome: results of the pivotal phase II/III study in patients with malignant ascites

Hypoxia Induces EMT in Low and Highly Aggressive Pancreatic Tumor Cells but Only Cells with Cancer Stem Cell Characteristics Acquire Pronounced Migratory Potential ⬇️

Immunosuppressive properties of anti-CD3 single-chain Fv and diabody

Immunotherapy of B-cell non-Hodgkin lymphoma by targeting the chemokine receptor CXCR5 in a preclinical mouse model

In vitro characterization of (177)Lu-radiolabelled chimeric anti-CD20 monoclonal antibody and a preliminary dosimetry study

Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma

L1 cell adhesion molecule as a potential therapeutic target in murine models of endometriosis using a monoclonal antibody approach

Lack of CD24 expression in mice reduces the number of leukocytes in the colon

Loss of Drop1 expression already at early tumor stages in a wide range of human carcinomas

Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage

Metalloprotease-mediated tumor cell shedding of B7-H6, the ligand of the natural killer cell-activating receptor NKp30.

Molecular and clinical dissection of CD24 antibody specificity by a comprehensive comparative analysis

Myofibroblast-induced tumorigenicity of pancreatic ductal epithelial cells is L1CAM dependent ⬇️

Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms

New Gene-Immunotherapy Combining TRAIL-Lymphocytes and EpCAMxCD3 Bispecific Antibody for Tumor Targeting ⬇️

Quality of recombinant protein determines the amount of autoreactivity detected against the tumor-associated epithelial cell adhesion molecule antigen: low frequency of antibodies against the natural protein.

Self-Antigen Presentation by Keratinocytes in the Inflamed Adult Skin Modulates T-Cell Auto-Reactivity

Sulforaphane Increases Drug-mediated Cytotoxicity Toward Cancer Stem-like Cells of Pancreas and Prostate ⬇️

Synergistic antitumor effect of bispecific CD19 x CD3 and CD19 x CD16 diabodies in a preclinical model of non-Hodgkin's lymphoma

Systematic comparison of surface coatings for protein microarrays

Target sequence accessibility limits activation-induced cytidine deaminase activity in primary mediastinal B-cell lymphoma

Targeting of cancer stem cell marker EpCAM by bispecific antibody EpCAMxCD3 inhibits pancreatic carcinoma

The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7

Therapeutic Potential of Amanitin-Conjugated Anti-Epithelial Cell Adhesion Molecule Monoclonal Antibody Against Pancreatic Carcinoma ⬇️

Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma.

Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis