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20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice

artículo científico publicado en 2010

A Pilot Study of the Feasibility of Confocal Endomicroscopy for Examination of the Human Airway ⬇️

artículo científico publicado el 1 de abril de 2010

A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma

artículo científico publicado en 2015

A fungal protease allergen provokes airway hyper-responsiveness in asthma

artículo científico publicado en 2015

A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm

artículo científico publicado en 2019

A novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2-adrenergic receptor internalization and down-regulation

artículo científico publicado en 2012

A-kinase anchoring proteins regulate compartmentalized cAMP signaling in airway smooth muscle

artículo científico publicado en 2012

Acetaminophen is both bronchodilatory and bronchoprotective in human precision cut lung slice airways

artículo científico publicado en 2019

Aclidinium bromide abrogates allergen-induced hyperresponsiveness and reduces eosinophilia in murine model of airway inflammation.

artículo científico publicado en 2010

Activation of p38 MAP-kinase and caldesmon phosphorylation are essential for urokinase-induced human smooth muscle cell migration

scientific article published on 01 January 2002

Adenoviral mediated anti-sense CD38 attenuates TNF-alpha-induced changes in calcium homeostasis of human airway smooth muscle cells

artículo científico publicado en 2005

Airway Smooth Muscle-Specific Transcriptomic Signatures of Glucocorticoid Exposure

artículo científico publicado en 2019

Airway epithelium stimulates smooth muscle proliferation

artículo científico publicado en 2009

Airway smooth muscle and immunomodulation in acute exacerbations of airway disease

artículo científico publicado en 2011

Airway smooth muscle as a regulator of immune responses and bronchomotor tone

artículo científico publicado en 2006

Airway smooth muscle as an immunomodulatory cell

artículo científico publicado en 2008

Airway smooth muscle cell hyperplasia: a therapeutic target in airway remodeling in asthma?

artículo científico publicado el 1 de enero de 2003

Airway smooth muscle cells are insensitive to the anti-proliferative effects of corticosteroids: The novel role of insulin growth factor binding Protein-1 in asthma

scientific article published on 23 May 2019

Airway smooth muscle cells enhance C3a-induced mast cell degranulation following cell-cell contact.

artículo científico publicado en 2005

Airway smooth muscle in asthma: just a target for bronchodilation?

artículo científico publicado en 2012

Airway smooth muscle in bronchial tone, inflammation, and remodeling: basic knowledge to clinical relevance

artículo científico publicado en 2007

Airway smooth muscle: a modulator of airway remodeling in asthma

artículo científico publicado en 2005

Airway smooth muscle: an immunomodulatory cell

artículo científico publicado en 2002

Airway smooth muscle: contraction and beyond.

artículo científico publicado en 2003

Airway smooth muscle: immunomodulatory cells that modulate airway remodeling? ⬇️

artículo científico publicado el 16 de septiembre de 2003

Airway smooth muscle: immunomodulatory cells?

artículo científico publicado en 2004

Altered CD38/Cyclic ADP-Ribose Signaling Contributes to the Asthmatic Phenotype ⬇️

artículo científico publicado el 20 de noviembre de 2012

An Official American Thoracic Society Research Statement: Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling.

artículo científico publicado en 2017

An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma

artículo científico publicado en 2012

An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma

artículo científico publicado en 2016

Anaphylatoxin C3a receptors in asthma

artículo científico publicado en 2005

Angiogenesis is induced by airway smooth muscle strain

artículo científico publicado en 2007

Anti-IgE or Anti-IL5: That Is the Question

artículo científico publicado en 2017

Anti-inflammatory Effects of Thiazolidinediones in Human Airway Smooth Muscle Cells ⬇️

artículo científico publicado el 24 de septiembre de 2010

Anti-mitogenic effects of β-agonists and PGE2 on airway smooth muscle are PKA dependent.

artículo científico publicado en 2010

Assays for in vitro monitoring of proliferation of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cells

scientific article published on 01 January 2006

Association of groundwater constituents with topography and distance to unconventional gas wells in NE Pennsylvania

artículo científico publicado en 2016

Asthma Yardstick: Practical recommendations for a sustained step-up in asthma therapy for poorly controlled asthma

artículo científico publicado en 2017

Asthma and COVID: What are the Important Questions?

artículo científico publicado en 2020

Asthma in the elderly: The role of exhaled nitric oxide measurements ⬇️

artículo científico publicado el 6 de marzo de 2013

Asthma in the elderly: a study of the role of vitamin D

artículo científico publicado en 2014

Asthma outcomes: biomarkers

artículo científico publicado en 2012

Asthma persistence versus progression: does airway smooth muscle function predict irreversible airflow obstruction?

artículo científico publicado en 2009

Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization

artículo científico publicado en 2003

Attitudes of physicians toward objective measures of airway function in asthma ⬇️

artículo científico publicado el 1 de abril de 2003

Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study

scientific article published on 07 September 2014

Beta-agonist-associated reduction in RGS5 expression promotes airway smooth muscle hyper-responsiveness.

artículo científico publicado en 2011

Biased TAS2R Bronchodilators Inhibit Airway Smooth Muscle Growth by Downregulating pERK1/2

article

Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines

artículo científico publicado en 2017

Biologic and Maintenance Systemic Corticosteroid Therapy Among U.S., Subspecialist-treated Severe Asthma Patients

scientific article published on 15 April 2020

Bitter taste receptor function in asthmatic and nonasthmatic human airway smooth muscle cells

artículo científico publicado en 2014

Bnip3 regulates airway smooth muscle cell focal adhesion and proliferation

artículo científico publicado en 2019

Bradykinin induces interleukin-6 production in human airway smooth muscle cells: modulation by Th2 cytokines and dexamethasone.

artículo científico publicado en 2003

Bronchial Thermoplasty: Targeting Structural Cells in Severe Persistent Asthma

artículo científico publicado en 2015

Bronchial hyperresponsiveness: insights into new signaling molecules.

artículo científico publicado en 2004

Bronchodilators, receptors and cross-talk: Together is better?

artículo científico

Budesonide enhances agonist-induced bronchodilation in human small airways by increasing cAMP production in airway smooth muscle

scientific article published on 20 November 2019

C-027 Inhibits IgE-mediated passive sensitization bronchoconstriction and acts as a histamine and serotonin antagonist in human airways ⬇️

artículo científico publicado el 1 de septiembre de 2011

CD2 Regulates Pathogenesis of Asthma Induced by House Dust Mice Extract

artículo científico publicado en 2020

CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen

scientific article published on 18 February 2019

CD38 and airway hyper-responsiveness: studies on human airway smooth muscle cells and mouse models

artículo científico publicado en 2015

CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle

artículo científico publicado en 2005

CD38/cyclic ADP-ribose-mediated Ca2+ signaling contributes to airway smooth muscle hyper-responsiveness

artículo científico publicado en 2003

CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies

artículo científico publicado en 2015

Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional study

artículo científico publicado en 2008

Clinical Issues in Severe Asthma: Consensus and Controversies on the Road to Precision Medicine

artículo científico publicado en 2018

Clinical Issues in Severe Asthma: Debates and Discussions About Personalizing Patient Management

artículo científico publicado en 2018

Comparison of the efficacy and safety of arformoterol 15 microg twice daily and arformoterol 30 microg once daily in COPD: a single-dose, multicenter, randomized, modified-blind, two-way crossover study

artículo científico

Cooperative mitogenic signaling by G protein-coupled receptors and growth factors is dependent on G(q/11)

scientific article published on 24 May 2006

Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth

artículo científico publicado en 2005

Correction: Unconventional Gas and Oil Drilling Is Associated with Increased Hospital Utilization Rates

artículo científico publicado en 2015

Cross-talk between tuberin, calmodulin, and estrogen signaling pathways

artículo científico publicado en 2005

Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration

artículo científico publicado en 2003

Cyclic mechanical strain-induced proliferation and migration of human airway smooth muscle cells: role of EMMPRIN and MMPs

artículo científico publicado en 2005

Cytokines regulate beta-2-adrenergic receptor responsiveness in airway smooth muscle via multiple PKA- and EP2 receptor-dependent mechanisms

artículo científico publicado en 2005

DHEA-S inhibits human neutrophil and human airway smooth muscle migration ⬇️

artículo científico publicado el 3 de julio de 2012

Defective Resensitization in Human Airway Smooth Muscle Cells Evokes β-Adrenergic Receptor Dysfunction in Severe Asthma

artículo científico publicado en 2015

Deficiency of melanoma differentiation-associated protein 5 results in exacerbated chronic postviral lung inflammation

scientific article published on February 2014

Defining an olfactory receptor function in airway smooth muscle cells.

artículo científico publicado en 2016

Deletion of microsomal prostaglandin E synthase-1 does not alter ozone-induced airway hyper-responsiveness

artículo científico publicado en 2010

Detection of SARS-CoV-2 is comparable in clinical samples preserved in saline or viral transport media

scientific article published on 13 May 2020

Development and characterization of pepducins as Gs-biased allosteric agonists

artículo científico publicado en 2014

Dexpramipexole depletes blood and tissue eosinophils in nasal polyps with no change in polyp size

artículo científico publicado en 2018

Diacylglycerol kinase ζ promotes allergic airway inflammation and airway hyperresponsiveness through distinct mechanisms

artículo científico publicado en 2019

Differential induction of CD38 expression by TNF-α in asthmatic airway smooth muscle cells ⬇️

artículo científico publicado el 6 de agosto de 2010

Does airway smooth muscle express an inflammatory phenotype in asthma? ⬇️

artículo científico publicado el 1 de mayo de 2011

Drug development for severe asthma: What are the metrics? ⬇️

artículo científico publicado el 22 de mayo de 2012

Effect of IL-1beta on CRE-dependent gene expression in human airway smooth muscle cells

artículo científico publicado en 2002

Effect of dexamethasone on beta2-adrenergic desensitization in airway smooth muscle: role of the ARG19 polymorphism

artículo científico publicado en 2003

Effects of corticosteroids on structural cells in asthma and chronic obstructive pulmonary disease

artículo científico publicado en 2004

Effects of rhinovirus 39 infection on airway hyperresponsiveness to carbachol in human airways precision cut lung slices

artículo científico publicado en 2018

Efficacy and safety of omalizumab in children and adolescents with moderate-to-severe asthma: A systematic literature review

artículo científico publicado en 2017

Elastomeric sensor surfaces for high-throughput single-cell force cytometry

scientific article published on 06 February 2018

Epithelium-generated neuropeptide Y induces smooth muscle contraction to promote airway hyperresponsiveness.

artículo científico publicado en 2016

Erratum

scholarly article published in European Respiratory Journal

Erratum

Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness.

artículo científico publicado en 2008

Exploiting functional domains of GRK2/3 to alter the competitive balance of pro- and anticontractile signaling in airway smooth muscle

artículo científico publicado en 2013

Exposure to Ambient Particulate Matter is Associated with Accelerated Functional Decline in Idiopathic Pulmonary Fibrosis.

artículo científico

Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFalpha and IL-13

artículo científico publicado en 2010

Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells

artículo científico publicado en 2008

Expression and muscarinic receptor coupling of Lyn kinase in cultured human airway smooth muscle cells

artículo científico publicado en 2005

Formaldehyde Induces Rho-Associated Kinase Activity to Evoke Airway Hyperresponsiveness

artículo científico publicado en 2016

Functional capacity, health status, and inflammatory biomarker profile in a cohort of patients with chronic obstructive pulmonary disease

artículo científico publicado en 2015

Functional expression of the GABAB receptor in human airway smooth muscle

artículo científico publicado en 2006

Functional expression of γ-amino butyric acid transporter 2 in human and guinea pig airway epithelium and smooth muscle

artículo científico publicado en 2010

G-protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-alpha-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells.

artículo científico publicado en 2005

GABAA receptors are expressed and facilitate relaxation in airway smooth muscle

artículo científico publicado en 2008

Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene

artículo científico publicado en 2012

Gi-Coupled γ-Aminobutyric Acid–B Receptors Cross-Regulate Phospholipase C and Calcium in Airway Smooth Muscle ⬇️

artículo científico publicado el 30 de junio de 2011

Glucocorticoid Receptor ChIP-Seq Identifies PLCD1 as a KLF15 Target that Represses Airway Smooth Muscle Hypertrophy

artículo científico publicado en 2017

Glucocorticoid and TNF signaling converge at A20 (TNFAIP3) to repress airway smooth muscle cytokine expression

artículo científico publicado en 2016

Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells

artículo científico publicado en 2010

Glucocorticoid regulation of CD38 expression in human airway smooth muscle cells: role of dual specificity phosphatase 1.

artículo científico publicado en 2008

Glucocorticoids rapidly activate cAMP production via Gαs to initiate non-genomic signaling that contributes to one-third of their canonical genomic effects

artículo científico publicado en 2019

Guiding principles for use of newer biologics and bronchial thermoplasty for patients with severe asthma.

artículo científico publicado en 2017

Gα12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner

artículo científico publicado en 2017

H2S relaxes isolated human airway smooth muscle cells via the sarcolemmal K(ATP) channel

scientific article published on 12 March 2014

Harmonized outcome measures for use in asthma patient registries and clinical practice

artículo científico publicado en 2019

House Dust Mite-Induced Allergic Airway Disease Is Independent of IgE and FcεRIα.

artículo científico publicado en 2017

How Important Is Adherence to Inhaled Medications Before Starting a Biologic Therapy for Asthma?

artículo científico publicado en 2018

Hyperpolarized 3He MRI in asthma measurements of regional ventilation following allergic sensitization and challenge in mice--preliminary results

artículo científico publicado en 2005

Hypoxia-induced Acidosis Uncouples the STIM-Orai Calcium Signaling Complex ⬇️

artículo científico publicado el 14 de noviembre de 2011

IFN-gamma inhibits human airway smooth muscle cell proliferation by modulating the E2F-1/Rb pathway

artículo científico publicado en 2003

IL-13 and IL-4 cause eotaxin release in human airway smooth muscle cells: a role for ERK.

artículo científico publicado en 2002

IL-13 and IL-4 promote TARC release in human airway smooth muscle cells: role of IL-4 receptor genotype

artículo científico publicado en 2003

IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle

artículo científico publicado en 2003

Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans.

artículo científico publicado en 2015

Impact of pulmonary artery pressure on exercise function in severe COPD.

artículo científico publicado en 2009

Important lessons learned from studies on the pharmacology of glucocorticoids in human airway smooth muscle cells: Too much of a good thing may be a problem

artículo científico publicado en 2020

In the clinic. Asthma

artículo científico publicado en 2007

Induction of ANGPTL4 expression in human airway smooth muscle cells by PMA through activation of PKC and MAPK pathways.

artículo científico publicado en 2009

Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner

artículo científico publicado en 2016

Inhibition of human airway smooth muscle cell proliferation by beta 2-adrenergic receptors and cAMP is PKA independent: evidence for EPAC involvement

artículo científico publicado en 2007

Inhibition of myristoylated alanine-rich C kinase substrate (MARCKS) protein inhibits ozone-induced airway neutrophilia and inflammation

artículo científico publicado en 2010

Inhibition of spleen tyrosine kinase attenuates IgE-mediated airway contraction and mediator release in human precision cut lung slices

artículo científico publicado en 2016

Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms

artículo científico publicado en 2015

Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation

artículo científico publicado en 2007

Interferons modulate mitogen-induced protein synthesis in airway smooth muscle

artículo científico publicado en 2010

Interleukin-13 and interleukin-4 induce vascular endothelial growth factor release from airway smooth muscle cells: role of vascular endothelial growth factor genotype

artículo científico publicado en 2005

Interleukin-9 influences chemokine release in airway smooth muscle: role of ERK.

artículo científico publicado en 2003

In vitro and in vivo pharmacological profile of PL-3994, a novel cyclic peptide (Hept-cyclo(Cys-His-Phe-d-Ala-Gly-Arg-d-Nle-Asp-Arg-Ile-Ser-Cys)-Tyr-[Arg mimetic]-NH(2)) natriuretic peptide receptor-A agonist that is resistant to neutral endopeptida

artículo científico publicado el 12 de noviembre de 2012

Irreversible airway obstruction in asthma: what we lose, we lose early

artículo científico

Is airway remodeling clinically relevant in asthma?

artículo científico publicado en 2003

Is airway smooth muscle the "missing link" modulating airway inflammation in asthma?

artículo científico publicado en 2008

Isoproterenol induces actin depolymerization in human airway smooth muscle cells via activation of an Src kinase and GS.

artículo científico publicado en 2005

Last Word on Point: Alterations in airway smooth muscle phenotype do cause airway hyperresponsiveness in asthma.

artículo científico publicado en 2012

Lipid-laden macrophages as biomarkers of vaping-associated lung injury

scientific article published on 01 February 2020

Loss of regulator of G protein signaling 5 promotes airway hyperresponsiveness in the absence of allergic inflammation.

artículo científico publicado en 2014

Mast cell chymase modifies cell-matrix interactions and inhibits mitogen-induced proliferation of human airway smooth muscle cells

artículo científico publicado en 2002

MicroRNA Mediated Chemokine Responses in Human Airway Smooth Muscle Cells

artículo científico publicado en 2016

MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway

artículo científico publicado en 2014

MicroRNA-203 negatively regulates c-Abl, ERK1/2 phosphorylation, and proliferation in smooth muscle cells

artículo científico publicado en 2015

MicroRNA-708 regulates CD38 expression through signaling pathways JNK MAP kinase and PTEN/AKT in human airway smooth muscle cells

artículo científico publicado en 2014

Mitogenic effects of cytokines on smooth muscle are critically dependent on protein kinase A and are unmasked by steroids and cyclooxygenase inhibitors

artículo científico publicado en 2007

Modulation of Bronchomotor Tone Pathways in Airway Smooth Muscle Function and Bronchomotor Tone in Asthma

scientific article published on 19 December 2018

Modulation of airway hyperresponsiveness by rhinovirus exposure

artículo científico publicado en 2018

Modulation of calcium homeostasis as a mechanism for altering smooth muscle responsiveness in asthma

artículo científico publicado en 2002

Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathway.

artículo científico publicado en 2004

Molecular Tension Probes to Investigate the Mechanopharmacology of Single Cells: A Step toward Personalized Mechanomedicine

artículo científico publicado en 2018

Natural history of asthma: persistence versus progression-does the beginning predict the end?

artículo científico publicado en 2008

Nebulized dehydroepiandrosterone-3-sulfate improves asthma control in the moderate-to-severe asthma results of a 6-week, randomized, double-blind, placebo-controlled study

artículo científico publicado el 1 de noviembre de 2010

Neutrophilic and Pauci-immune Phenotypes in Severe Asthma

artículo científico publicado en 2016

Non-genomic Effects of Glucocorticoids: An Updated View

scientific article published on 26 November 2018

Noncontractile functions of airway smooth muscle cells in asthma

artículo científico publicado en 2009

Obesity increases airway smooth muscle responses to contractile agonists

scientific article published on 30 August 2018

Oncostatin M causes VEGF release from human airway smooth muscle: synergy with IL-1beta

artículo científico publicado en 2005

Oncostatin M causes eotaxin-1 release from airway smooth muscle: Synergy with IL-4 and IL-13

artículo científico publicado en 2005

Onset of Effect, Changes in Airflow Obstruction and Lung Volume, and Health-Related Quality of Life Improvements with Benralizumab for Patients with Severe Eosinophilic Asthma: Phase IIIb Randomized, Controlled Trial (SOLANA)

scientific article published on 17 February 2020

Ozone modulates IL-6 secretion in human airway epithelial and smooth muscle cells

artículo científico publicado en 2009

PDE8 is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2AR-AC6.

artículo científico publicado en 2017

PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells

scientific article published on 01 August 2002

Patient-reported outcomes in moderate-to-severe allergic asthmatics treated with omalizumab: a systematic literature review of randomized controlled trials

artículo científico publicado en 2017

Patients' and primary care physicians' beliefs about asthma control and risk

artículo científico publicado en 2009

Paucigranulocytic asthma: Uncoupling of airway obstruction from inflammation

scientific article published on 19 June 2018

Pepducins as a potential treatment strategy for asthma and COPD

artículo científico publicado en 2018

Phenotype of asthmatics with increased airway S-nitrosoglutathione reductase activity

artículo científico publicado en 2014

Phosphatidylinositol 3-kinase but not tuberin is required for PDGF-induced cell migration

artículo científico publicado en 2002

Phosphodiesterases regulate airway smooth muscle function in health and disease

artículo científico publicado en 2007

Phosphoinositide 3-Kinase in Asthma: Novel Roles and Therapeutic Approaches

artículo científico publicado en 2016

Placebo response in asthma: a robust and objective phenomenon.

artículo científico publicado en 2007

Point: alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma

artículo científico publicado en 2012

Polycyclic Aromatic Hydrocarbons Impair Function of β2-Adrenergic Receptors in Airway Epithelial and Smooth Muscle Cells ⬇️

artículo científico publicado el 26 de mayo de 2011

Prevalence of SARS-CoV-2 infection in previously undiagnosed health care workers at the onset of the U.S. COVID-19 epidemic

artículo científico publicado en 2020

Profile of aclidinium bromide in the treatment of chronic obstructive pulmonary disease ⬇️

artículo científico publicado el 16 de septiembre de 2011

Publisher Correction: Elastomeric sensor surfaces for high-throughput single-cell force cytometry

artículo científico publicado en 2018

RGS4 Overexpression in Lung Attenuates Airway Hyper-responsiveness in Mice

artículo científico publicado en 2017

RGS4 promotes allergen- and aspirin-associated airway hyper-responsiveness by inhibiting PGE2 biosynthesis

scientific article published on 18 March 2020

RNA-Seq transcriptome profiling identifies CRISPLD2 as a glucocorticoid responsive gene that modulates cytokine function in airway smooth muscle cells

artículo científico publicado en 2014

Raf-1 kinase mediates adenylyl cyclase sensitization by TNF-alpha in human airway smooth muscle cells

artículo científico publicado en 2007

Raf-1, Actin Dynamics, and Abelson Tyrosine Kinase in Human Airway Smooth Muscle Cells ⬇️

artículo científico publicado el 18 de octubre de 2012

Real-world Clinical Characteristics, Treatment Patterns, and Exacerbations in US Patients With Asthma Newly Treated With Omalizumab

scientific article published on 23 July 2018

Receptors and pathways mediating the effects of prostaglandin E2 on airway tone

artículo científico publicado en 2002

Regulation of CD38 expression in human airway smooth muscle cells: role of class I phosphatidylinositol 3 kinases ⬇️

artículo científico publicado el 3 de mayo de 2012

Regulation of TNF-alpha- and IFN-gamma-induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease

artículo científico publicado en 2003

Regulation of inflammation by airway smooth muscle

artículo científico publicado en 2008

Regulation of phospholipase A2 by interleulin-1 in human airway smooth muscle.

artículo científico publicado en 2003

Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-alpha and dexamethasone

artículo científico publicado en 2008

Regulator of G protein signaling 2 is a key modulator of airway hyperresponsiveness.

artículo científico publicado en 2012

Regulator of G protein signaling 5 restricts neutrophil chemotaxis and trafficking

scientific article published in Journal of Biological Chemistry

Regulator of G-protein signaling 2 repression exacerbates airway hyper-responsiveness and remodeling in asthma

artículo científico publicado en 2015

Regulator of G-protein signaling-5 inhibits bronchial smooth muscle contraction in severe asthma.

artículo científico publicado en 2012

Regulatory features of interleukin-1beta-mediated prostaglandin E2 synthesis in airway smooth muscle

artículo científico publicado en 2005

Response to C3a, mast cells, and asthma

scientific article published on 01 February 2006

Reviewer acknowledgement 2012

Reviewer acknowledgement 2013

Reviewer acknowledgement 2014

Reviewer acknowledgement 2015

Revisiting John Snow to Meet the Challenge of Nontuberculous Mycobacterial Lung Disease

scientific article published on 01 November 2019

Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling

artículo científico publicado en 2003

Salicylic acid amplifies Carbachol-induced bronchoconstriction in human precision-cut lung slices

Selected Contribution: TNF-α modulates murine tracheal rings responsiveness to G-protein-coupled receptor agonists and KCl ⬇️

artículo científico publicado el 2 de mayo de 2003

Serum amyloid A: an ozone-induced circulating factor with potentially important functions in the lung-brain axis

artículo científico publicado en 2017

Severe Asthma: Challenges and Precision Approaches to Therapy

Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis.

scientific article published on 13 July 2009

Social stress and asthma: the role of corticosteroid insensitivity

scientific article published on 11 February 2010

Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production

artículo científico publicado en 2009

Soluble Guanylate Cyclase Agonists Induce Bronchodilation in Human Small Airways

artículo científico publicado en 2020

Soluble guanylate cyclase as an alternative target for bronchodilator therapy in asthma

artículo científico publicado en 2016

Sphingosine-1-phosphate stimulates contraction of human airway smooth muscle cells

artículo científico publicado en 2003

Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration

artículo científico publicado en 2004

Steroids completely reverse albuterol-induced beta(2)-adrenergic receptor tolerance in human small airways

artículo científico publicado en 2008

Synthetic Secoisolariciresinol Diglucoside (LGM2605) Protects Human Lung in an Ex Vivo Model of Proton Radiation Damage.

artículo científico publicado en 2017

Synthetic responses in airway smooth muscle

artículo científico publicado en 2004

TAS2R activation promotes airway smooth muscle relaxation despite β2-adrenergic receptor tachyphylaxis ⬇️

artículo científico publicado el 8 de junio de 2012

TENOR Revisited

artículo científico publicado en 2020

TGF-beta potentiates airway smooth muscle responsiveness to bradykinin

artículo científico publicado en 2005

TGF-β1 Evokes Human Airway Smooth Muscle Cell Shortening and Hyperresponsiveness via Smad3.

artículo científico publicado en 2017

TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation.

artículo científico publicado en 2009

TNF-α Regulation of CD38 Expression in Human Airway Smooth Muscle: Role of MAP Kinases and NF-κB ⬇️

artículo científico publicado el 1 de enero de 2011

Targeting airway smooth muscle in airways diseases: an old concept with new twists ⬇️

artículo científico publicado el 1 de diciembre de 2011

Thank you and farewell after 15 years editing respiratory research

article by Jan Lötvall & Reynold A Panettieri published 26 November 2018 in Respiratory Research

The BJP expects authors to share data

artículo científico publicado en 2019

The COVID-19 pandemic and research shutdown: staying safe and productive

scientific article published on 03 April 2020

The Gulf Coast Health Alliance: Health Risks Related to the Macondo Spill (GC-HARMS) Study: Self-Reported Health Effects.

artículo científico publicado en 2017

The Role of Neutrophils in Asthma

artículo científico publicado en 2018

The dopamine D2receptor is expressed and sensitizes adenylyl cyclase activity in airway smooth muscle ⬇️

artículo científico publicado el 30 de septiembre de 2011

The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells

artículo científico publicado en 2005

The effect of multiple allergen immunotherapy on exhaled nitric oxide in adults with allergic rhinitis ⬇️

artículo científico publicado el 19 de agosto de 2013

The nuclear membrane leukotriene synthetic complex is a signal integrator and transducer ⬇️

artículo científico publicado el 26 de septiembre de 2012

The safety and efficacy of zileuton controlled-release tablets as adjunctive therapy to usual care in the treatment of moderate persistent asthma: a 6-month randomized controlled study

artículo científico publicado en 2007

Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): two randomised, double-blind, placebo-controlled, phase 3 clinical trials

artículo científico publicado en 2018

Tralokinumab for the treatment of severe, uncontrolled asthma: the ATMOSPHERE clinical development program

artículo científico publicado en 2018

Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: role of NF-kappaB and sensitivity to glucocorticoids

artículo científico publicado en 2006

Transforming Growth Factor β1 Function in Airway Remodeling and Hyperresponsiveness. The Missing Link?

artículo científico publicado en 2016

Transforming Growth Factor-β1 Decreases β2-Agonist-induced Relaxation in Human Airway Smooth Muscle

scientific article published on 01 August 2019

Transgenic smooth muscle expression of the human CysLT1 receptor induces enhanced responsiveness of murine airways to leukotriene D4

artículo científico publicado en 2004

Treatment of severe, uncontrolled eosinophilic asthma: Where we are heading

artículo científico publicado en 2018

Trichostatin A abrogates airway constriction, but not inflammation, in murine and human asthma models

artículo científico publicado en 2012

Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)

scientific journal article

Tumor necrosis factor alpha modulates airway smooth muscle function via the autocrine action of interferon beta

artículo científico publicado en 2003

Tumor necrosis factor-alpha differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-beta-dependent CD38 pathway

artículo científico publicado en 2004

Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: modulation by glucocorticoids and beta-agonists

artículo científico publicado en 2002

Unconventional gas and oil drilling is associated with increased hospital utilization rates

artículo científico publicado en 2015

Upregulated P-Rex1 exacerbates human airway smooth muscle hyperplasia in asthma

scientific article published on 10 October 2018

Upregulation of Mas-related G Protein coupled receptor X2 in asthmatic lung mast cells and its activation by the novel neuropeptide hemokinin-1.

artículo científico publicado en 2018

Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis

artículo científico publicado en 2016

Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma

artículo científico publicado en 2015

Vitamin D modulates airway smooth muscle function in COPD ⬇️

artículo científico publicado el 25 de febrero de 2012

Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway

scientific journal article

miR-140-3p regulation of TNF-α-induced CD38 expression in human airway smooth muscle cells

artículo científico publicado en 2012

p38 MAPK inhibitors, IKK2 inhibitors, and TNFα inhibitors in COPD ⬇️

artículo científico publicado el 24 de febrero de 2012

sGC redox regulation and asthma.

artículo científico publicado en 2015

β-Agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent.

artículo científico publicado en 2014

β2-Adrenergic Receptor Agonists Modulate Human Airway Smooth Muscle Cell Migration via Vasodilator-Stimulated Phosphoprotein ⬇️

artículo científico publicado el 1 de enero de 2012

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