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A Blueprint for HIV Vaccine Discovery

artículo científico publicado en 2012

A Conserved HIV gp120 Glycoprotein Structure Involved in Chemokine Receptor Binding

artículo científico publicado el 19 de junio de 1998

A General Approach for Receptor and Antibody-Targeted Detection of Native Proteins Utilizing Split-Luciferase Reassembly

artículo científico publicado el 15 de octubre de 2010

A Tyrosine-Rich Region in the N Terminus of CCR5 Is Important for Human Immunodeficiency Virus Type 1 Entry and Mediates an Association between gp120 and CCR5

artículo científico publicado el 1 de febrero de 1998

A method for identification of HIV gp140 binding memory B cells in human blood

artículo científico publicado en 2008

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

artículo científico publicado en 2010

Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

artículo científico publicado en 2003

Altered differentiation is central to HIV-specific CD4+ T cell dysfunction in progressive disease

scientific article published on 15 July 2019

An HIV-1 Env-Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes.

artículo científico publicado en 2016

An aptamer that neutralizes R5 strains of human immunodeficiency virus type 1 blocks gp120-CCR5 interaction

artículo científico publicado en 2005

Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals

artículo científico publicado en 2008

Analysis of the Interaction of Antibodies with a Conserved, Enzymatically Deglycosylated Core of the HIV Type 1 Envelope Glycoprotein 120

artículo científico publicado el 10 de febrero de 1998

Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles

artículo científico publicado en 2007

Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein

artículo científico publicado el 1 de diciembre de 1997

Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins

artículo científico publicado en 2005

Anti-HIV B Cell lines as candidate vaccine biosensors

artículo científico publicado en 2012

Antibody 17b binding at the coreceptor site weakens the kinetics of the interaction of envelope glycoprotein gp120 with CD4.

artículo científico publicado en 2001

Antigen-Specific Single B Cell Sorting and Monoclonal Antibody Cloning in Guinea Pigs

artículo científico publicado en 2019

B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.

artículo científico publicado en 2008

B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates

artículo científico publicado en 2013

BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses

artículo científico publicado en 2012

Biochemical and immunogenic characterization of soluble human immunodeficiency virus type 1 envelope glycoprotein trimers expressed by semliki forest virus

artículo científico publicado en 2005

Biochemically Defined HIV-1 Envelope Glycoprotein Variant Immunogens Display Differential Binding and Neutralizing Specificities to the CD4-binding Site

artículo científico publicado el 13 de diciembre de 2011

Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables

artículo científico publicado en 2009

Broad HIV-1 neutralization mediated by CD4-binding site antibodies

artículo científico publicado en 2007

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

artículo científico publicado en 2014

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

artículo científico publicado en 2012

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

artículo científico publicado en 2009

CD4-Independent Binding of SIV gp120 to Rhesus CCR5

artículo científico publicado el 21 de noviembre de 1997

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

artículo científico publicado en 1996

CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies

artículo científico publicado en 2014

CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization

artículo científico publicado en 2008

Calcium Phosphate Nanoparticle-Based Vaccines as a Platform for Improvement of HIV-1 Env Antibody Responses by Intrastructural Help

scientific article published on 27 September 2019

Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants

artículo científico publicado en 2006

Characterization of antibody responses to purified HIV-1 gp120 glycoproteins fused with the molecular adjuvant C3d

artículo científico publicado en 2005

Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity

artículo científico publicado en 2007

Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins

artículo científico publicado en 2000

Chemical cross-linking of HIV-1 Env for direct TLR7/8 ligand conjugation compromises recognition of conserved antigenic determinants

artículo científico publicado el 15 de agosto de 2013

Cleavage-Independent HIV-1 Trimers From CHO Cell Lines Elicit Robust Autologous Tier 2 Neutralizing Antibodies

artículo científico publicado en 2018

Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design

artículo científico publicado en 2015

Conformation of the HIV-1 gp 120 envelope glycoprotein

artículo científico publicado en 1996

Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic

artículo científico publicado en 1999

Correction for Chakrabarti et al., Robust Neutralizing Antibodies Elicited by HIV-1 JRFL Envelope Glycoprotein Trimers in Nonhuman Primates

artículo científico publicado en 2014

Correction for Ingale et al., Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies

artículo científico publicado en 2015

Correction for Khan et al., "Targeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of Entry".

artículo científico publicado en 2019

Correction: Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

artículo científico publicado en 2016

Corrigendum to “A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples”

scholarly article published in Journal of Immunological Methods

Covalent Linkage of HIV-1 Trimers to Synthetic Liposomes Elicits Improved B Cell and Antibody Responses

artículo científico publicado en 2017

Dense Array of Spikes on HIV-1 Virion Particles

artículo científico publicado en 2017

Design clues from functional constraints and broadly neutralizing antibodies

Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer

artículo científico publicado en 2018

Direct antibody access to the HIV-1 membrane-proximal external region positively correlates with neutralization sensitivity

artículo científico publicado en 2011

Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization

artículo científico publicado en 2015

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model

artículo científico publicado en 2017

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model.

artículo científico publicado en 2018

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

artículo científico publicado en 2017

Elicitation of structure-specific antibodies by epitope scaffolds

artículo científico publicado en 2010

Energetics of the HIV gp120-CD4 binding reaction

artículo científico publicado en 2000

Engineered mice and B cell lines expressing broadly neutralizing antibodies and their unmutated precursors: tools for HIV vaccinology.

artículo científico publicado en 2012

Enhanced expression, native purification, and characterization of CCR5, a principal HIV-1 coreceptor

artículo científico publicado en 1999

Evolution of B cell analysis and Env trimer redesign

artículo científico publicado en 2017

Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses

artículo científico publicado en 2020

Factors limiting the immunogenicity of HIV-1 gp120 envelope glycoproteins

artículo científico publicado en 2004

Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140.

artículo científico publicado en 2008

Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

artículo científico publicado en 2008

Glutaraldehyde Cross-linking of HIV-1 Env Trimers Skews the Antibody Subclass Response in Mice

artículo científico publicado en 2017

Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein

artículo científico publicado en 2017

HIV Type 1 Env Precursor Cleavage State Affects Recognition by Both Neutralizing and Nonneutralizing gp41 Antibodies

artículo científico publicado el 19 de enero de 2011

HIV vaccine design and the neutralizing antibody problem

artículo científico publicado en 2004

HIV-1 Cross-reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Non-human Primate

artículo científico publicado en 2017

HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins

artículo científico publicado el 8 de agosto de 2012

HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation

artículo científico publicado en 2016

HIV-1 envelope glycoprotein trimer immunogenicity elicited in the presence of human CD4 alters the neutralization profile

artículo científico publicado en 2014

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

artículo científico publicado en 2002

HIV-1 neutralizing antibodies display dual specificity for the primary and coreceptor binding sites and preferential recognition of fully-cleaved Env.

artículo científico publicado en 2012

HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization

artículo científico publicado en 2014

Heterologous epitope-scaffold prime:boosting immuno-focuses B cell responses to the HIV-1 gp41 2F5 neutralization determinant

artículo científico publicado en 2011

High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells.

artículo científico publicado en 2016

High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence.

artículo científico publicado en 2016

High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site

artículo científico publicado en 2012

Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin

artículo científico publicado en 2002

Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein.

artículo científico publicado en 2008

Human plasmacytoid dendritic cells efficiently capture HIV-1 envelope glycoproteins via CD4 for antigen presentation

artículo científico publicado en 2013

Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies

artículo científico publicado en 2014

Immunization with recombinant HLA classes I and II, HIV-1 gp140, and SIV p27 elicits protection against heterologous SHIV infection in rhesus macaques.

artículo científico publicado en 2011

Immunization with wild-type or CD4-binding-defective HIV-1 Env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus

artículo científico publicado en 2010

Immunogenicity of HIV-1 envelope glycoprotein oligomers

artículo científico publicado en 2009

Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers

artículo científico publicado en 2001

Independent expansion of epitope-specific plasma cell responses upon HIV-1 envelope glycoprotein immunization.

artículo científico publicado en 2013

Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates

artículo científico publicado en 2009

Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.

artículo científico publicado en 1998

Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding

artículo científico publicado en 1995

Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor

artículo científico publicado en 2016

Ligand accessibility to the HIV-1 Env co-receptor binding site can occur prior to CD4 engagement and is independent of viral tier category.

artículo científico publicado en 2018

Mechanism of Neutralization by the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01

artículo científico publicado el 29 de junio de 2011

Mechanism of human immunodeficiency virus type 1 resistance to monoclonal antibody B12 that effectively targets the site of CD4 attachment

artículo científico publicado en 2009

Migration of antigen-specific T cells away from CXCR4-binding human immunodeficiency virus type 1 gp120.

artículo científico publicado en 2004

Modifications that stabilize human immunodeficiency virus envelope glycoprotein trimers in solution

artículo científico publicado en 2000

Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding

artículo científico publicado en 2016

Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein

artículo científico publicado en 2002

OA05-05. Impact of in vivo CD4 binding during HIV-1 Env trimer immunizations of rhesus macaques.

artículo científico publicado en 2009

Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus

artículo científico publicado en 2000

Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization

scientific article published on 01 December 2019

P05-07. Evaluation of peripheral and bone marrow B cell responses in rhesus macaques after immunization with soluble HIV-1 gp140 trimers

artículo científico publicado en 2009

P09-05. Mechanism of HIV-1 resistance to a monoclonal antibody that effectively targets the site of CD4 attachment

article

P09-13. Structure of HIV-1 gp41 interactive region: layered architecture and basis of conformational mobility

article

P12-12. Analysis of antibody and B cell responses following inoculation with computationally designed HIV-1 2F5 epitope scaffold proteins

artículo científico publicado en 2009

P19-08. Immunisation with recombinant HLA class I and II, HIV-1gp140 and SIVp27 antigens elicits protection against SHIV-SF162P4 infection in rhesus macaques.

artículo científico publicado en 2009

PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4.

artículo científico publicado en 2012

Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach

artículo científico publicado en 2017

Phosphoserine acidic cluster motifs bind distinct basic regions on the μ subunits of clathrin adaptor protein complexes

scientific article published in Journal of Biological Chemistry

Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation

artículo científico publicado en 2015

Priming with DNA encoding functional trimers and boosting with soluble trimeric protein elicited tier 2 neutralizing antibodies in non-human primates

artículo científico publicado en 2012

Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1).

artículo científico publicado en 1999

Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies

artículo científico publicado en 1994

Proof of principle for epitope-focused vaccine design

artículo científico publicado en 2014

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

artículo científico publicado en 2010

Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region

artículo científico publicado en 2009

Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region

artículo científico publicado el 1 de diciembre de 1992

Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis

artículo científico publicado en 2015

Robust Neutralizing Antibodies Elicited by HIV-1 JRFL Envelope Glycoprotein Trimers in Nonhuman Primates

artículo científico publicado el 25 de septiembre de 2013

Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity

artículo científico publicado en 2020

Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth

artículo científico publicado en 2005

Selection Pressure on HIV-1 Envelope by Broadly Neutralizing Antibodies to the Conserved CD4-Binding Site

artículo científico publicado el 14 de marzo de 2012

Selective expansion of HIV-1 envelope glycoprotein-specific B cell subsets recognizing distinct structural elements following immunization

artículo científico publicado en 2009

Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120

artículo científico publicado en 2000

Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage.

artículo científico publicado en 2005

Short Communication: Immunogenicity of DNA Vaccines Expressing Human Immunodeficiency Virus Type 1 Envelope Glycoprotein with and without Deletions in the V1/2 and V3 Regions

artículo científico publicado el 20 de enero de 1998

Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization

artículo científico publicado en 2014

Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.

artículo científico publicado en 2008

Solid-phase proteoliposomes containing human immunodeficiency virus envelope glycoproteins

artículo científico publicado en 2002

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

artículo científico publicado en 2010

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: characterization and ligand binding analysis

artículo científico publicado en 2005

Stabilization of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Trimers by Disulfide Bonds Introduced into the gp41 Glycoprotein Ectodomain

artículo científico publicado el 1 de septiembre de 1998

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

artículo científico publicado en 2009

Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120

artículo científico publicado en 2004

Structural definition of a conserved neutralization epitope on HIV-1 gp120

artículo científico publicado en 2007

Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

artículo científico publicado en 2004

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

artículo científico publicado en 2011

Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

artículo científico publicado en 2010

Structure of a V3-containing HIV-1 gp120 core

artículo científico publicado en 2005

Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.

artículo científico publicado en 2018

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

artículo científico publicado el 18 de junio de 1998

Structure-Guided Redesign Improves NFL HIV Env Trimer Integrity and Identifies an Inter-Protomer Disulfide Permitting Post-Expression Cleavage

scientific article published on 17 July 2018

Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers

artículo científico publicado en 2015

Structure-activity relationships in the binding of chemically derivatized CD4 to gp120 from human immunodeficiency virus

artículo científico publicado en 2007

Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site

artículo científico publicado en 2009

Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition.

artículo científico publicado en 2003

Structure-guided Alterations of the gp41-directed HIV-1 Broadly Neutralizing Antibody 2F5 Reveal New Properties Regarding its Neutralizing Function

artículo científico publicado el 19 de julio de 2012

Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

artículo científico publicado en 2000

Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

artículo científico publicado en 2007

Studies with monoclonal antibodies to the V3 region of HIV-1 gp120 reveal limitations to the utility of solid-phase peptide binding assays

artículo científico publicado en 1994

Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment

artículo científico publicado en 2019

Synthetic multivalent V3 glycopeptides display enhanced recognition by glycan-dependent HIV-1 broadly neutralizing antibodies

artículo científico publicado en 2017

Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

artículo científico publicado en 2016

Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response

artículo científico publicado en 2017

Targeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of Entry

scholarly article by Salar N Khan et al published 15 September 2018 in Journal of Virology

The Envelope Glycoprotein Ectodomains Determine the Efficiency of CD4+ T Lymphocyte Depletion in Simian– Human Immunodeficiency Virus–Infected Macaques

artículo científico publicado el 21 de septiembre de 1998

The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization

article

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

artículo científico publicado el 19 de junio de 1998

The antigenic structure of the HIV gp120 envelope glycoprotein

artículo científico publicado el 18 de junio de 1998

The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.

artículo científico publicado en 2008

Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies

artículo científico publicado en 2016

Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

artículo científico publicado en 1999

Tyrosine-sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry

artículo científico publicado en 2008

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

scientific article published on 12 November 2019

Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site

artículo científico publicado en 2015

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers

scholarly article by Matthias G Pauthner et al published 15 January 2019 in Immunity

Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

artículo científico publicado en 2014

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

artículo científico publicado en 2017

Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties

artículo científico publicado en 2015