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A multi-system approach assessing the interaction of anticonvulsants with P-gp

artículo científico publicado en 2013

Abnormal megakaryopoiesis and platelet function in cyclooxygenase-2-deficient mice

artículo científico publicado en 2015

Adenosine receptors regulate gap junction coupling of the human cerebral microvascular endothelial cells hCMEC/D3 by Ca2+ influx through cyclic nucleotide-gated channels

artículo científico publicado en 2017

Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging

artículo científico publicado en 2012

Cyclooxygenase-2–Derived Prostacyclin Regulates Arterial Thrombus Formation by Suppressing Tissue Factor in a Sirtuin-1–Dependent-Manner

artículo científico publicado en 2012

Cytokines present in smokers' serum interact with smoke components to enhance endothelial dysfunction

artículo científico publicado en 2011

Development of a three-dimensional, all-human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models

artículo científico publicado en 2011

Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier

artículo científico publicado en 2008

Differential permissivity of human cerebrovascular endothelial cells to enterovirus infection and specificities of serotype EV-A71 in crossing an in vitro model of the human blood-brain barrier

artículo científico publicado en 2015

Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C

artículo científico publicado en 2014

Effect of cigarette smoke on monocyte procoagulant activity: Focus on platelet-derived brain-derived neurotrophic factor (BDNF).

artículo científico publicado en 2016

Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown

artículo científico publicado en 2010

Expression and localization of claudins-3 and -12 in transformed human brain endothelium

artículo científico publicado en 2012

Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment

artículo científico publicado en 2009

Hepatitis C virus infects the endothelial cells of the blood-brain barrier

artículo científico publicado en 2011

Hyperosmotic stress induces Axl activation and cleavage in cerebral endothelial cells

artículo científico publicado en 2008

Identification of peptide ligands for targeting to the blood-brain barrier

artículo científico publicado en 2010

Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies

artículo científico publicado en 2007

Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier

artículo científico publicado en 2012

Lamotrigine is a substrate for OCT1 in brain endothelial cells

artículo científico publicado en 2011

Modulation of blood-brain barrier permeability by neutrophils: in vitro and in vivo studies

artículo científico publicado en 2009

Paracrine signalling of inflammatory cytokines from an in vitro blood brain barrier model upon exposure to polymeric nanoparticles

artículo científico publicado en 2013

Peripheral blood CD4+ T lymphocytes from multiple sclerosis patients are characterized by higher PSGL-1 expression and transmigration capacity across a human blood-brain barrier-derived endothelial cell line

artículo científico publicado en 2009

Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System

artículo científico publicado en 2016

Production of prostaglandin E2 induced by cigarette smoke modulates tissue factor expression and activity in endothelial cells

artículo científico publicado en 2015

Purine receptors and Ca(2+) signalling in the human blood-brain barrier endothelial cell line hCMEC/D3

artículo científico publicado en 2011

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

artículo científico publicado en 2007

Role of KCNMA1 gene in breast cancer invasion and metastasis to brain

artículo científico publicado en 2009

Somatostatin preserved blood brain barrier against cytokine induced alterations: possible role in multiple sclerosis

artículo científico publicado en 2013

Suppressing PTEN activity by tobacco smoke plus interleukin-1beta modulates dissociation of VE-cadherin/beta-catenin complexes in endothelium

artículo científico publicado en 2008

Temporal profile of matrix metalloproteinases and their inhibitors in a human endothelial cell culture model of cerebral ischemia

artículo científico publicado en 2013

The hCMEC/D3 cell line as a model of the human blood brain barrier

artículo científico

The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies

artículo científico publicado en 2008

The involvement of a Na⁺- and Cl⁻-dependent transporter in the brain uptake of amantadine and rimantadine

artículo científico publicado en 2012

The poorly membrane permeable antipsychotic drugs amisulpride and sulpiride are substrates of the organic cation transporters from the SLC22 family

artículo científico publicado en 2014

Tobacco smoke regulates the expression and activity of microsomal prostaglandin E synthase-1: role of prostacyclin and NADPH-oxidase

artículo científico publicado en 2011

Transcellular targeting of fiber- and hexon-modified adenovirus vectors across the brain microvascular endothelial cells in vitro

artículo científico publicado en 2012

Transthyretin participates in beta-amyloid transport from the brain to the liver--involvement of the low-density lipoprotein receptor-related protein 1?

artículo científico publicado en 2016

Uptake and permeability studies of BBB-targeting immunoliposomes using the hCMEC/D3 cell line

artículo científico publicado en 2010