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A gene-delivery system specific for hepatoma cells and an intracellular kinase signal based on human liver-specific bionanocapsules and signal-responsive artificial polymer.

artículo científico publicado en 2010

A hydrophilic polymer grafted with a histone tail peptide as an artificial gene regulator.

artículo científico publicado en 2011

A novel double-coating carrier produced by solid-in-oil and solid-in-water nanodispersion technology for delivery of genes and proteins into cells.

artículo científico publicado en 2012

A protein kinase assay based on FRET between quantum dots and fluorescently-labeled peptides

artículo científico publicado en 2013

A protein kinase signal-responsive gene carrier modified RGD peptide.

artículo científico publicado en 2006

A short peptide is a protein kinase C (PKC) alpha-specific substrate.

artículo científico publicado en 2008

A syngeneic hepatocellular carcinoma model rapidly and simply prepared using a hydrodynamics-based procedure.

artículo científico publicado en 2008

An intracellular kinase signal-responsive gene carrier for disordered cell-specific gene therapy.

artículo científico publicado en 2005

Bio and nanotechnological strategies for tumor-targeted gene therapy.

artículo científico publicado en 2010

Cellular signal-specific peptide substrate is essential for the gene delivery system responding to cellular signals.

artículo científico publicado en 2009

Colorimetric enzymatic activity assay based on noncrosslinking aggregation of gold nanoparticles induced by adsorption of substrate peptides.

artículo científico publicado en 2008

Design of polymeric carriers for cancer-specific gene targeting: utilization of abnormal protein kinase Calpha activation in cancer cells.

artículo científico publicado en 2008

Drug delivery system based on responses to an HIV infectious signal.

artículo científico publicado en 2008

Effect of introduction of chondroitin sulfate into polymer-peptide conjugate responding to intracellular signals.

artículo científico publicado en 2011

Effect of peptide content on the regulation of transgene expression by protein kinase Cα-responsive linear polyethylenimine-peptide conjugates.

artículo científico publicado en 2014

Effect of the addition of diammonium citrate to alpha-cyano-4-hydroxycinnamic acid (CHCA) matrix for the detection of phosphorylated peptide in phosphorylation reactions using cell and tissue lysates.

artículo científico publicado en 2007

Effective delivery of DNA into tumor cells and tissues by electroporation of polymer-DNA complex

artículo científico publicado en 2008

Efficient delivery of signal-responsive gene carriers for disease-specific gene expression via bubble liposomes and sonoporation

artículo científico publicado en 2017

Fluorescent nanoparticles consisting of lipopeptides and fluorescein-modified polyanions for monitoring of protein kinase activity.

artículo científico publicado en 2011

Fluorescent polyion complex nanoparticle that incorporates an internal standard for quantitative analysis of protein kinase activity

artículo científico publicado en 2014

Fluorometric detection of protein kinase Cα activity based on phosphorylation-induced dissociation of a polyion complex.

artículo científico publicado en 2012

Gene carrier showing all-or-none response to cancer cell signaling.

artículo científico publicado en 2012

Hepatoma-targeted gene delivery using a tumor cell-specific gene regulation system combined with a human liver cell-specific bionanocapsule.

artículo científico publicado en 2010

High-throughput colorimetric detection of tyrosine kinase inhibitors based on the aggregation of gold nanoparticles.

artículo científico publicado en 2007

Improvement in the colloidal stability of protein kinase-responsive polyplexes by PEG modification

artículo científico publicado en 2012

Inflammatory cell-specific transgene expression system responding to Ikappa-B kinase beta activation.

artículo científico publicado en 2009

Letter: correlation between phosphorylation ratios by matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis and enzyme kinetics.

artículo científico publicado en 2008

Mass-tag technology responding to intracellular signals as a novel assay system for the diagnosis of tumor

artículo científico publicado en 2006

Measurement of homogeneous kinase activity for cell lysates based on the aggregation of gold nanoparticles.

artículo científico publicado en 2007

Modification of ligands for serum albumin on polyethyleneimine to stabilize polyplexes in gene delivery

artículo científico

Molecular mechanism of caspase-3-induced gene expression of polyplexes formed from polycations grafted with cationic substrate peptides.

artículo científico publicado en 2009

Monitoring protein kinase activity in cell lysates using a high-density peptide microarray.

artículo científico publicado en 2009

Peptide substrates for G protein-coupled receptor kinase 2.

artículo científico publicado en 2014

Peptide substrates for Rho-associated kinase 2 (Rho-kinase 2/ROCK2)

artículo científico publicado en 2011

Phosphorylation of Rho-associated kinase (Rho-kinase/ROCK/ROK) substrates by protein kinases A and C.

artículo científico publicado en 2006

Plasma protein kinase C (PKC)alpha as a biomarker for the diagnosis of cancers

artículo científico publicado en 2009

Protein kinase C (PKC) isozyme-specific substrates and their design.

artículo científico publicado en 2012

Protein kinase C alpha-specific peptide substrate graft-type copolymer for cancer cell-specific gene regulation systems.

artículo científico publicado en 2009

Protein kinase Calpha-responsive polymeric carrier: its application for gene delivery into human cancers.

artículo científico publicado en 2009

Regulation of Transgene Expression in Tumor Cells by Exploiting Endogenous Intracellular Signals.

artículo científico publicado en 2008

Reversal of efflux of an anticancer drug in human drug-resistant breast cancer cells by inhibition of protein kinase Cα (PKCα) activity

artículo científico publicado en 2015

Role of estrogenic compounds (diethylstibestrol, 17beta-estradiol, and bisphenol A) in the phosphorylation of substrate by protein kinase Calpha.

artículo científico publicado en 2009

Role of plasma as activator and cofactor in phosphorylation catalyzed by protein kinase C

artículo científico publicado en 2008

Serum protein kinase Cα as a diagnostic biomarker of cancers.

artículo científico publicado en 2013

Stabilization of cancer-specific gene carrier via hydrophobic interaction for a clear-cut response to cancer signaling.

artículo científico publicado en 2013

Tumor therapy by gene regulation system responding to cellular signal.

artículo científico publicado en 2010