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A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure

artículo científico publicado en 2014

A chitinase-like protein in the lung and circulation of patients with severe asthma

artículo científico publicado en 2007

A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system

artículo científico publicado en 2007

A glycoengineered anti‐CD19 antibody with potent antibody‐dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo

artículo científico publicado el 9 de septiembre de 2011

Acute, but not resolved, influenza A infection enhances susceptibility to house dust mite-induced allergic disease

artículo científico publicado en 2009

Angiopoietin-2-driven vascular remodeling in airway inflammation

artículo científico publicado en 2010

B-cell depletion in vitro and in vivo with an afucosylated anti-CD19 antibody

artículo científico publicado en 2010

B7-H3 promotes acute and chronic allograft rejection

artículo científico publicado en 2005

Capillary defects and exaggerated inflammatory response in the airways of EphA2-deficient mice

artículo científico publicado en 2009

Cell Type-Specific Recognition of Human Metapneumoviruses (HMPVs) by Retinoic Acid-Inducible Gene I (RIG-I) and TLR7 and Viral Interference of RIG-I Ligand Recognition by HMPV-B1 Phosphoprotein

artículo científico publicado en 2010

Characterization of Tiki, a New Family of Wnt-specific Metalloproteases

artículo científico publicado en 2015

Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction.

artículo científico publicado en 2002

Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions

artículo científico publicado en 2009

Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling

artículo científico publicado en 2003

Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation

artículo científico publicado en 2006

Correction: Type I Interferon: Potential Therapeutic Target for Psoriasis?

artículo científico publicado en 2009

Cutaneous antigen priming via gene gun leads to skin-selective Th2 immune-inflammatory responses

artículo científico publicado en 2005

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

scientific journal article

Development of Potential Pharmacodynamic and Diagnostic Markers for Anti-IFN-α Monoclonal Antibody Trials in Systemic Lupus Erythematosus

artículo científico publicado en 2009

Differential expression and function of breast regression protein 39 (BRP-39) in murine models of subacute cigarette smoke exposure and allergic airway inflammation

artículo científico publicado el 7 de abril de 2011

Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice

artículo científico publicado en 2011

Effect of GM-CSF on immune, inflammatory, and clinical responses to ragweed in a novel mouse model of mucosal sensitization

artículo científico publicado en 2003

Eosinophils Are Dispensable for Allergic Remodeling and Immunity in a Model of House Dust Mite–induced Airway Disease

artículo científico publicado el 23 de agosto de 2010

Essential role for the C5a receptor in regulating the effector phase of synovial infiltration and joint destruction in experimental arthritis

artículo científico publicado en 2002

Evaluation of inducible costimulator/B7-related protein-1 as a therapeutic target in a murine model of allergic airway inflammation

artículo científico publicado en 2003

Genomic-based high throughput screening identifies small molecules that differentially inhibit the antiviral and immunomodulatory effects of IFN-alpha

artículo científico publicado en 2008

Granulocyte macrophage colony-stimulating factor-driven respiratory mucosal sensitization induces Th2 differentiation and function independently of interleukin-4.

artículo científico publicado en 2002

HMGB1 and RAGE in inflammation and cancer

artículo científico publicado en 2010

ICOS controls the pool size of effector-memory and regulatory T cells.

artículo científico publicado en 2008

ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: increased ICOS expression enhances the effector function of both Th1 and Th2 cells

artículo científico publicado en 2004

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

artículo científico publicado en 2003

IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice

artículo científico publicado en 2011

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization.

artículo científico publicado en 2012

IL-4 increases type 2, but not type 1, cytokine production in CD8+ T cells from mild atopic asthmatics

artículo científico publicado en 2005

IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways

artículo científico publicado en 2010

IL‐9 is a Th17‐derived cytokine that limits pathogenic activity in organ‐specific autoimmune disease

artículo científico publicado el 24 de febrero de 2011

Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family

artículo científico publicado en 2002

Impact of CD40 ligand, B cells, and mast cells in peanut-induced anaphylactic responses

artículo científico publicado en 2007

In vivo-to-in silico iterations to investigate aeroallergen-host interactions

artículo científico publicado en 2008

Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance

scientific journal article

Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism

artículo científico publicado en 2004

Lung chitinolytic activity and chitotriosidase are elevated in chronic obstructive pulmonary disease and contribute to lung inflammation

artículo científico publicado en 2009

Macrophage impairment underlies airway occlusion in primary respiratory syncytial virus bronchiolitis

artículo científico publicado en 2008

Mast cells are essential intermediaries in regulatory T-cell tolerance

artículo científico publicado en 2006

Mycophenolic Acid Differentially Impacts B Cell Function Depending on the Stage of Differentiation

artículo científico publicado el 26 de agosto de 2011

Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus

artículo científico publicado en 2009

Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan

artículo científico publicado en 2003

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

artículo científico publicado en 2004

Novel Anti-TM4SF1 Antibody-Drug Conjugates with Activity against Tumor Cells and Tumor Vasculature

artículo científico publicado en 2015

Opposing Roles of Membrane and Soluble Forms of the Receptor for Advanced Glycation End Products in Primary Respiratory Syncytial Virus Infection

artículo científico publicado el 18 de enero de 2012

Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk

scientific journal article

RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA

artículo científico publicado en 2013

RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.

artículo científico publicado en 2014

RSV-induced bronchial epithelial cell PD-L1 expression inhibits CD8+ T cell nonspecific antiviral activity

artículo científico publicado en 2011

Role of CCL11 in eosinophilic lung disease during respiratory syncytial virus infection

artículo científico publicado en 2005

Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema

artículo científico publicado en 2005

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis

scientific article published on 04 May 2009

Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis

artículo científico publicado en 2006

Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma

artículo científico publicado en 2010

Shifting of immune responsiveness to house dust mite by influenza A infection: genomic insights.

artículo científico publicado en 2011

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

artículo científico publicado en 2002

Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance.

artículo científico publicado en 2003

Type I IFNs Regulate Inflammation, Vasculopathy, and Fibrosis in Chronic Cutaneous Graft-versus-Host Disease

artículo científico publicado en 2016

Type I interferon: potential therapeutic target for psoriasis?

artículo científico publicado en 2008

Type I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis.

artículo científico publicado en 2009

YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar macrophages

artículo científico publicado en 2008