Lista de obras -

A Systematic Review of Biomarkers and Risk of Incident Type 2 Diabetes: An Overview of Epidemiological, Prediction and Aetiological Research Literature

artículo científico publicado en 2016

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

artículo científico publicado en 2012

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genome-wide association study of neuroticism in a population-based sample

artículo científico publicado en 2010

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

artículo científico publicado en 2009

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

artículo científico publicado en 2011

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

artículo científico publicado en 2016

A low-frequency variant in MAPK14 provides mechanistic evidence of a link with myeloperoxidase: a prognostic cardiovascular risk marker

artículo científico publicado en 2014

A phenome-wide association study of a lipoprotein-associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults

artículo científico publicado en 2016

An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank

artículo científico publicado en 2019

Association of ABCB1 genetic variants with renal function in Africans and in Caucasians

artículo científico publicado en 2008

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Body Mass Index and Risk of Nonalcoholic Fatty Liver Disease: Two Electronic Health Record Prospective Studies

artículo científico publicado en 2015

CUBN is a gene locus for albuminuria

artículo científico publicado en 2011

Cardiovascular and Lifestyle Risk Factors and Cognitive Function in Patients With Stable Coronary Heart Disease

Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males

artículo científico publicado en 2011

Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals

artículo científico publicado en 2009

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

artículo científico publicado en 2013

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

artículo científico publicado en 2010

Common variants near MC4R are associated with fat mass, weight and risk of obesity

artículo científico publicado en 2008

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Corrigendum: Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

scholarly article published in Nature Genetics

Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation

artículo científico publicado en 2012

Definitions of Metabolic Health and Risk of Future Type 2 Diabetes in BMI Categories: A Systematic Review and Network Meta-analysis

artículo científico publicado en 2015

Disentangling the genetics of lean mass

article

Erratum to: The epigenetic signature of systemic insulin resistance in obese women.

artículo científico publicado en 2016

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

artículo científico publicado en 2016

FGF21 signalling pathway and metabolic traits - genetic association analysis

artículo científico publicado en 2010

Factors influencing longitudinal changes of circulating liver enzyme concentrations in subjects randomized to placebo in four clinical trials

scientific article published on 29 November 2018

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

artículo científico publicado en 2009

Genetic and phenotypic architecture of metabolic syndrome-associated components in dyslipidemic and normolipidemic subjects: The GEMS Study

article

Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array

artículo científico publicado en 2010

Genetic loci influencing kidney function and chronic kidney disease

artículo científico publicado en 2010

Genetic polymorphisms of the main transcription factors for adiponectin gene promoter in regulation of adiponectin levels: association analysis in three European cohorts

artículo científico publicado en 2012

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

artículo científico publicado en 2010

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation in LIN28B is associated with the timing of puberty

artículo científico publicado en 2009

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

artículo científico publicado en 2009

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association studies using an adaptive two-stage analysis for a case-control design

artículo científico publicado en 2007

Genome-wide association study identifies 48 common genetic variants associated with handedness

artículo científico publicado en 2020

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

artículo científico publicado en 2011

Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

artículo científico publicado en 2010

Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links

artículo científico publicado en 2014

Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study

artículo científico publicado en 2009

Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene

artículo científico publicado en 2010

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

artículo científico publicado en 2016

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Identification and validation of copy number variants using SNP genotyping arrays from a large clinical cohort

artículo científico publicado en 2012

Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci.

artículo científico publicado en 2019

Interaction between insulin (VNTR) and hepatic lipase (LIPC-514C>T) variants on the response to an oral glucose tolerance test in the EARSII group of young healthy men.

artículo científico publicado en 2005

Interleukin-18 as a drug repositioning opportunity for inflammatory bowel disease: A Mendelian randomization study

artículo científico publicado en 2019

LDL-cholesterol concentrations: a genome-wide association study

artículo científico publicado en 2008

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

artículo científico publicado en 2010

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

artículo científico publicado en 2016

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

artículo científico publicado en 2017

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Lipoprotein-Associated Phospholipase A2 Loss-of-Function Variant and Risk of Vascular Diseases in 90,000 Chinese Adults

artículo científico publicado en 2016

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

artículo científico publicado en 2015

Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease

artículo científico publicado en 2018

Male-pattern baldness susceptibility locus at 20p11.

artículo científico publicado en 2008

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

artículo científico publicado en 2010

Meta-analysis of 26,638 Individuals Identifies Two Genetic Loci Associated with Left Ventricular Ejection Fraction

artículo científico publicado en 2020

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

artículo científico publicado en 2009

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

artículo científico publicado en 2009

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

artículo científico publicado en 2020

Methods for testing association between uncertain genotypes and quantitative traits

artículo científico publicado en 2010

Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia

artículo científico publicado en 2005

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

No interaction between alcohol consumption and HDL-related genes on HDL cholesterol levels

artículo científico publicado en 2010

Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults

scientific article published on 08 October 2019

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Novel method to estimate the phenotypic variation explained by genome-wide association studies reveals large fraction of the missing heritability

artículo científico publicado en 2011

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation.

artículo científico publicado en 2011

Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib

artículo científico publicado en 2017

Pharmacological effects of lipid-lowering drugs recapitulate with a larger amplitude the phenotypic effects of common variants within their target genes

artículo científico publicado en 2008

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

artículo científico publicado en 2020

Phenome-wide association study using research participants' self-reported data provides insight into the Th17 and IL-17 pathway

artículo científico publicado en 2017

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

artículo científico publicado en 2016

Polymorphisms in CYP-7A1, not APOE, influence the change in plasma lipids in response to population dietary change in an 8 year follow-up; results from the Czech MONICA study

artículo científico publicado en 2003

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

artículo científico publicado en 2008

Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease.

artículo científico publicado en 2011

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease

article

Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project).

artículo científico publicado en 2005

Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts

scientific article published on 20 May 2019

Serum insulin and inflammatory markers in overweight individuals with and without dyslipidemia

artículo científico publicado en 2007

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

artículo científico publicado en 2009

Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases

artículo científico publicado en 2012

The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome

artículo científico publicado en 2008

The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research

artículo científico publicado en 2008

The PsyCoLaus study: methodology and characteristics of the sample of a population-based survey on psychiatric disorders and their association with genetic and cardiovascular risk factors

artículo científico publicado en 2009

The benefits of using genetic information to design prevention trials

artículo científico publicado en 2013

The epigenetic signature of systemic insulin resistance in obese women

artículo científico publicado en 2016

The genetics of drug efficacy: opportunities and challenges

artículo científico publicado en 2016

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

artículo científico publicado en 2010

Urotensin-II system in genetic control of blood pressure and renal function

artículo científico publicado en 2013

Variants in MTNR1B influence fasting glucose levels

artículo científico publicado en 2008

Lista de obras de

A Systematic Review of Biomarkers and Risk of Incident Type 2 Diabetes: An Overview of Epidemiological, Prediction and Aetiological Research Literature

A catalog of genetic loci associated with kidney function from analyses of a million individuals

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

A genome-wide association search for type 2 diabetes genes in African Americans

A genome-wide association study of neuroticism in a population-based sample

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

A low-frequency variant in MAPK14 provides mechanistic evidence of a link with myeloperoxidase: a prognostic cardiovascular risk marker

A phenome-wide association study of a lipoprotein-associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults

An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank

Association of ABCB1 genetic variants with renal function in Africans and in Caucasians

Biological, clinical and population relevance of 95 loci for blood lipids

Body Mass Index and Risk of Nonalcoholic Fatty Liver Disease: Two Electronic Health Record Prospective Studies

CUBN is a gene locus for albuminuria

Cardiovascular and Lifestyle Risk Factors and Cognitive Function in Patients With Stable Coronary Heart Disease

Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males

Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

Common variants near MC4R are associated with fat mass, weight and risk of obesity

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

Corrigendum: Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation

Definitions of Metabolic Health and Risk of Future Type 2 Diabetes in BMI Categories: A Systematic Review and Network Meta-analysis

Disentangling the genetics of lean mass

Erratum to: The epigenetic signature of systemic insulin resistance in obese women.

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

FGF21 signalling pathway and metabolic traits - genetic association analysis

Factors influencing longitudinal changes of circulating liver enzyme concentrations in subjects randomized to placebo in four clinical trials

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

Genetic and phenotypic architecture of metabolic syndrome-associated components in dyslipidemic and normolipidemic subjects: The GEMS Study

Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array

Genetic loci influencing kidney function and chronic kidney disease

Genetic polymorphisms of the main transcription factors for adiponectin gene promoter in regulation of adiponectin levels: association analysis in three European cohorts

Genetic studies of body mass index yield new insights for obesity biology

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

Genetic variation in LIN28B is associated with the timing of puberty

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

Genome-wide association studies using an adaptive two-stage analysis for a case-control design

Genome-wide association study identifies 48 common genetic variants associated with handedness

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links

Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study

Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Identification and validation of copy number variants using SNP genotyping arrays from a large clinical cohort

Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci.

Interaction between insulin (VNTR) and hepatic lipase (LIPC-514C>T) variants on the response to an oral glucose tolerance test in the EARSII group of young healthy men.

Interleukin-18 as a drug repositioning opportunity for inflammatory bowel disease: A Mendelian randomization study

LDL-cholesterol concentrations: a genome-wide association study

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Lipoprotein-Associated Phospholipase A2 Loss-of-Function Variant and Risk of Vascular Diseases in 90,000 Chinese Adults

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease

Male-pattern baldness susceptibility locus at 20p11.

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

Meta-analysis of 26,638 Individuals Identifies Two Genetic Loci Associated with Left Ventricular Ejection Fraction

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

Methods for testing association between uncertain genotypes and quantitative traits

Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

No interaction between alcohol consumption and HDL-related genes on HDL cholesterol levels

Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals