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A Basic ApoE-Based Peptide Mediator to Deliver Proteins across the Blood-Brain Barrier: Long-Term Efficacy, Toxicity, and Mechanism

artículo científico publicado en 2017

A brain-to-blood carrier-mediated transport system for small, N-Tyrosinated peptides ⬇️

artículo científico publicado el 1 de diciembre de 1984

A decade of changing perceptions about neuropeptides

artículo científico publicado en 1990

A giant prolactinoma and the effect of chronic bromocriptine therapy on basal and TRH-stimulated serum prolactin levels

artículo científico publicado en 1991

A novel antioxidant N-acetylcysteine amide prevents gp120- and Tat-induced oxidative stress in brain endothelial cells

artículo científico publicado en 2006

A physiological role for amyloid-beta protein:enhancement of learning and memory

artículo científico publicado en 2010

Adiponectin does not cross the blood-brain barrier but modifies cytokine expression of brain endothelial cells

artículo científico publicado en 2006

Adsorptive endocytosis mediates the passage of hiv-1 across the blood-brain barrier: Evidence for a post-internalization coreceptor ⬇️

artículo científico publicado el 1 de febrero de 1998

Adsorptive endocytosis of HIV-1gp120 by blood-brain barrier is enhanced by lipopolysaccharide

artículo científico publicado en 1999

Age-Associated Changes in the Immune System and Blood⁻Brain Barrier Functions ⬇️

article

Aging and the blood-brain barrier: changes in the carrier-mediated transport of peptides in rats

artículo científico publicado en 1985

Alpha Adrenergic Induction of Transport of Lysosomal Enzyme across the Blood-Brain Barrier

artículo científico publicado en 2015

Alpha synuclein is transported into and out of the brain by the blood-brain barrier

artículo científico publicado en 2014

Alterations in Plasma microRNA and Protein Levels in War Veterans with Chronic Mild Traumatic Brain Injury

artículo científico publicado en 2020

Aluminum alters the permeability of the blood-brain barrier to some non-peptides

artículo científico publicado en 1985

Aluminum complexing enhances amyloid beta protein penetration of blood-brain barrier

artículo científico publicado en 2006

Aluminum-sensitive degradation of amyloid beta-protein 1-40 by murine and human intracellular enzymes

artículo científico publicado en 1996

Alzheimer's disease through the eye of a mouse. Acceptance lecture for the 2001 Gayle A. Olson and Richard D. Olson prize

artículo científico publicado en 2002

Analgesia and the blood-brain barrier transport system for Tyr-MIF-1/enkephalins: evidence for a dissociation

artículo científico publicado en 1988

Angiotensin II modulates BBB permeability via activation of the AT(1) receptor in brain endothelial cells

artículo científico publicado en 2009

Anorectic effects of circulating cytokines: role of the vascular blood-brain barrier

artículo científico publicado en 2001

Antagonists of growth hormone-releasing hormone cross the blood-brain barrier: a potential applicability to treatment of brain tumors

artículo científico publicado en 2005

Anti-IL-6 neutralizing antibody modulates blood-brain barrier function in the ovine fetus

artículo científico publicado en 2015

Anti-amyloid beta protein antibody passage across the blood-brain barrier in the SAMP8 mouse model of Alzheimer's disease: an age-related selective uptake with reversal of learning impairment

artículo científico publicado en 2007

Antibody blood-brain barrier efflux is modulated by glycan modification

artículo científico publicado en 2017

Antibody to beta-amyloid protein increases acetylcholine in the hippocampus of 12 month SAMP8 male mice

artículo científico publicado en 2003

Antisense against Amyloid-β Protein Precursor Reverses Memory Deficits and Alters Gene Expression in Neurotropic and Insulin-Signaling Pathways in SAMP8 Mice

artículo científico publicado en 2015

Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice

artículo científico publicado en 2004

ApoE and cerebral insulin: Trafficking, receptors, and resistance

scientific article published on 21 January 2020

Assessing blood granulocyte colony-stimulating factor as a potential biomarker of acute traumatic brain injury in mice and humans

artículo científico publicado en 2015

Bidirectional passage of peptides across the blood-brain barrier

artículo científico publicado el 1 de enero de 1992

Binding of Tyr-MIF-1 to isolated brain capillaries

artículo científico publicado en 1986

Binding, internalization, and membrane incorporation of human immunodeficiency virus-1 at the blood-brain barrier is differentially regulated

artículo científico publicado en 2004

Blast exposure elicits blood-brain barrier disruption and repair mediated by tight junction integrity and nitric oxide dependent processes

scientific article published on 27 July 2018

Blind mice are not impaired in T-maze footshock avoidance acquisition and retention

artículo científico publicado en 2002

Blood to brain transport of interleukin links the immune and central nervous systems

scientific article published on 01 January 1991

Blood-Brain Barrier Disruption and Neurovascular Unit Dysfunction in Diabetic Mice: Protection with the Mitochondrial Carbonic Anhydrase Inhibitor Topiramate

artículo científico publicado en 2016

Blood-Brain Barriers in Obesity.

artículo científico publicado en 2017

Blood-borne interleukin-1 alpha is transported across the endothelial blood-spinal cord barrier of mice.

artículo científico publicado en 1994

Blood-brain barrier and energy balance

artículo científico publicado en 2006

Blood-brain barrier as a regulatory interface

artículo científico publicado en 2009

Blood-brain barrier dysfunction as a cause and consequence of Alzheimer's disease.

artículo científico publicado en 2013

Blood-brain barrier transport of cytokines: a mechanism for neuropathology

artículo científico publicado en 2005

Blood–Brain Barrier Permeability to Ebiratide and TNF in Acute Spinal Cord Injury ⬇️

artículo científico publicado el 1 de agosto de 1997

Brain distribution and behavioral effects of progesterone and pregnenolone after intranasal or intravenous administration

artículo científico publicado en 2010

Brain meets body: the blood-brain barrier as an endocrine interface

artículo científico publicado en 2012

Brain microvascular pericytes are immunoactive in culture: cytokine, chemokine, nitric oxide, and LRP-1 expression in response to lipopolysaccharide

artículo científico publicado en 2011

Brain pericytes increase the lipopolysaccharide-enhanced transcytosis of HIV-1 free virus across the in vitro blood-brain barrier: evidence for cytokine-mediated pericyte-endothelial cell crosstalk

artículo científico publicado en 2013

Brain uptake of the glucagon-like peptide-1 antagonist exendin(9-39) after intranasal administration

artículo científico publicado en 2004

Brain-immune communication pathways

artículo científico publicado en 2007

Brain-to-blood transport of peptides and the alcohol withdrawal syndrome

artículo científico publicado en 1994

CSF-plasma relationships for DSIP and some other neuropeptides

artículo científico publicado en 1983

Carrier-Mediated Transport of Labeled Oxytocin from Brain to Blood ⬇️

artículo científico publicado el 1 de mayo de 1991

Carrier-mediated transport of vasopressin across the blood-brain barrier of the mouse

artículo científico publicado en 1987

Central Nervous System Delivery of Intranasal Insulin: Mechanisms of Uptake and Effects on Cognition

artículo científico publicado en 2015

Central and peripheral administration of antisense oligonucleotide targeting amyloid-β protein precursor improves learning and memory and reduces neuroinflammatory cytokines in Tg2576 (AβPPswe) mice

artículo científico publicado en 2014

Central nervous system effects of peptides, 1980-1985: a cross-listing of peptides and their central actions from the first six years of the journal Peptides

artículo científico publicado en 1986

Characteristics of compounds that cross the blood-brain barrier

artículo científico publicado en 2009

Characterization of blood-brain barrier permeability to PYY3-36 in the mouse

artículo científico publicado en 2003

Characterization of lectin-mediated brain uptake of HIV-1 GP120.

artículo científico publicado en 1998

Chronic ethanol consumption impairs learning and memory after cessation of ethanol.

artículo científico publicado en 2005

Chronic peripheral administration of somatostatin receptor subtype-4 agonist NNC 26-9100 enhances learning and memory in SAMP8 mice ⬇️

artículo científico publicado el 24 de diciembre de 2010

Commentary on the 2018 Named Series on blood-brain interfaces: Roles of neuroimmunomodulation in health and disease

article

Comparison of the rate of dedifferentiation with increasing passages among cell sources for an in vitro model of the blood-brain barrier

scientific article published on 07 May 2020

Conjugates of superoxide dismutase 1 with amphiphilic poly(2-oxazoline) block copolymers for enhanced brain delivery: synthesis, characterization and evaluation in vitro and in vivo

artículo científico publicado en 2012

Copper complexing decreases the ability of amyloid beta peptide to cross the BBB and enter brain parenchyma

artículo científico publicado en 2007

Cytokine and chemokine responses in serum and brain after single and repeated injections of lipopolysaccharide: multiplex quantification with path analysis.

artículo científico publicado en 2011

D-[Ala1]-peptide T-amide is transported from blood to brain by a saturable system

artículo científico publicado en 1987

DHEAS improves learning and memory in aged SAMP8 mice but not in diabetic mice

artículo científico publicado en 2004

Decreased levels of PSD95 and two associated proteins and increased levels of BCl2 and caspase 3 in hippocampus from subjects with amnestic mild cognitive impairment: Insights into their potential roles for loss of synapses and memory, accumulation

scientific article published on 01 February 2010

Delivery across the blood-brain barrier of antisense directed against amyloid beta: reversal of learning and memory deficits in mice overexpressing amyloid precursor protein

artículo científico publicado en 2001

Delivery of galanin-like peptide to the brain: targeting with intranasal delivery and cyclodextrins

artículo científico publicado en 2008

Delivery of peptides to the brain: emphasis on therapeutic development

artículo científico publicado en 2008

Delivery of testosterone to the brain by intranasal administration: comparison to intravenous testosterone

artículo científico publicado en 2009

Delta sleep-inducing peptide (DSIP)-like material is absorbed by the gastrointestinal tract of the neonatal rat.

artículo científico publicado en 1983

Delta sleep-inducing peptide crosses the blood-brain-barrier in dogs: some correlations with protein binding

artículo científico publicado en 1982

Denial versus dualism: the blood-brain barrier as an interface of the gut-brain axis

artículo científico publicado en 2006

Designing stable blood-brain barrier-permeable prosaptide peptides for treatment of central nervous system neurodegeneration

artículo científico publicado en 2000

Developing drugs that can cross the blood-brain barrier: applications to Alzheimer's disease

artículo científico publicado en 2008

Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier

scholarly article

Differential effect of aluminum on the blood-brain barrier transport of peptides, technetium and albumin

artículo científico publicado en 1988

Differential metabolism of Tyr-MIF-1 and MIF-1 in rat and human plasma

artículo científico publicado en 1994

Differential penetration of DSIP peptides into rat brain

artículo científico publicado en 1982

Differential permeability of the blood-brain barrier to two pancreatic peptides: insulin and amylin

artículo científico publicado en 1998

Differential transport of a secretin analog across the blood-brain and blood-cerebrospinal fluid barriers of the mouse

artículo científico publicado en 2002

Differentiating the Influences of Aging and Adiposity on Brain Weights, Levels of Serum and Brain Cytokines, Gastrointestinal Hormones, and Amyloid Precursor Protein

artículo científico publicado en 2014

Disability in obese elderly women: Lower limb strength and recreational physical activity

artículo científico publicado en 2007

Disruption of the hippocampal and hypothalamic blood-brain barrier in a diet-induced obese model of type II diabetes: prevention and treatment by the mitochondrial carbonic anhydrase inhibitor, topiramate

article

Disruption of the integrity and function of brain microvascular endothelial cells in culture by exposure to diesel engine exhaust particles

artículo científico publicado en 2013

Diurnal uptake of circulating interleukin-1alpha by brain, spinal cord, testis and muscle

artículo científico publicado en 1998

Drug delivery to the brain in Alzheimer's disease: consideration of the blood-brain barrier

artículo científico

Drug transport into the central nervous system: using newer findings about the blood-brain barriers

artículo científico publicado en 2012

Effect of Diabetes Mellitus on the Permeability of the Blood–Brain Barrier to Insulin ⬇️

artículo científico publicado el 1 de enero de 1997

Effect of LPS on the permeability of the blood-brain barrier to insulin

artículo científico publicado en 2001

Effect of alpha-lipoic acid on memory, oxidation, and lifespan in SAMP8 mice

artículo científico publicado en 2012

Effect of cardiac arrest on brain weight and the permeability of the blood-brain and blood-spinal cord barrier to albumin and tumor necrosis factor-alpha

artículo científico publicado en 1999

Effect of controlled cortical impact on the passage of pituitary adenylate cyclase activating polypeptide (PACAP) across the blood-brain barrier

artículo científico publicado en 2017

Effect of dietary n-3 polyunsaturated fatty acids on brain lipid fatty acid composition, learning ability, and memory of senescence-accelerated mouse

artículo científico publicado en 2008

Effect of lipopolysaccharide on the transport of pituitary adenylate cyclase activating polypeptide across the blood-brain barrier

artículo científico publicado en 2005

Effect of spinal cord injury on the permeability of the blood-brain and blood-spinal cord barriers to the neurotropin PACAP.

artículo científico publicado en 1998

Effects of N-acetylcysteine amide (NACA), a novel thiol antioxidant against glutamate-induced cytotoxicity in neuronal cell line PC12.

artículo científico publicado en 2005

Effects of a behaviorally active antibody on the brain uptake and clearance of amyloid beta proteins

artículo científico publicado en 2005

Effects of a growth hormone-releasing hormone antagonist on telomerase activity, oxidative stress, longevity, and aging in mice

artículo científico publicado en 2010

Effects of chronic ethanol administration on brain interstitial fluid levels of Methionine-enkephalin as measured by microdialysis in vivo

artículo científico publicado en 2006

Effects of chronic ethanol on brain and serum level of methionine enkephalin

artículo científico publicado en 2003

Effects of leptin on memory processing

artículo científico publicado en 2005

Effects of lipopolysaccharide on leptin transport across the blood-brain barrier

artículo científico publicado en 2004

Effects of orexin-A on memory processing

artículo científico publicado en 2002

Effects of peptides: a cross-listing of peptides and their central actions published in the journal Peptides from 1994 through 1998.

artículo científico publicado en 1999

Effects of triglycerides, obesity, and starvation on ghrelin transport across the blood-brain barrier

artículo científico publicado en 2008

Effects of various reproductive hormones on the penetration of LHRH across the blood-brain barrier

artículo científico publicado el 1 de enero de 1992

Endogenous peptide Tyr-Pro-Trp-Gly-NH2 (Tyr-W-MIF-1) is transported from the brain to the blood by peptide transport system-1.

artículo científico publicado en 1993

Enhanced leptin transport across the blood-brain barrier by alpha 1-adrenergic agents

artículo científico publicado en 2001

Enkephalin, PPE mRNA, and PTS-1 in alcohol withdrawal seizure-prone and -resistant mice ⬇️

artículo científico publicado el 1 de enero de 1998

Entry of DSIP peptides into dog CSF: role of physicochemical and pharmacokinetic parameters

artículo científico publicado en 1986

Entry of blood-borne cytokines into the central nervous system: effects on cognitive processes

artículo científico publicado en 2002

Epinephrine enhances lysosomal enzyme delivery across the blood brain barrier by up-regulation of the mannose 6-phosphate receptor

artículo científico publicado en 2007

Erratum

Estradiol potentiates acetylcholine and glutamate-mediated post-trial memory processing in the hippocampus

artículo científico publicado en 2000

Ethanol alters the concentration of Met-enkephalin in brain by affecting peptide transport system-1 independent of preproenkephalin mRNA.

artículo científico publicado en 1997

Evidence that [125I]N-Tyr-delta sleep-inducing peptide crosses the blood-brain barrier by a non-competitive mechanism

artículo científico publicado en 1984

Evidence that the species barrier of human immunodeficiency virus-1 does not extend to uptake by the blood--brain barrier: comparison of mouse and human brain microvessels

artículo científico publicado en 2005

Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure

artículo científico publicado en 2002

Extra virgin olive oil improves learning and memory in SAMP8 mice.

artículo científico publicado en 2012

Extreme stability of Tyr-MIF-1 in CSF.

artículo científico publicado en 1994

Fate of leptin after intracerebroventricular injection into the mouse brain

artículo científico publicado en 1998

From blood-brain barrier to blood-brain interface: new opportunities for CNS drug delivery

artículo científico publicado en 2016

Genetics and sex influence peripheral and central innate immune responses and blood-brain barrier integrity

artículo científico publicado en 2018

Ghrelin controls hippocampal spine synapse density and memory performance

artículo científico publicado en 2006

Ghrelin transport across the blood-brain barrier can occur independently of the growth hormone secretagogue receptor

artículo científico publicado en 2018

Ghrelin-induced feeding is dependent on nitric oxide

artículo científico publicado en 2003

Granulocyte-macrophage colony-stimulating factor crosses the blood-- brain and blood--spinal cord barriers ⬇️

artículo científico publicado el 1 de noviembre de 1997

Gut reactions: How the blood-brain barrier connects the microbiome and the brain.

artículo científico publicado en 2017

HIV proteins (gp120 and Tat) and methamphetamine in oxidative stress-induced damage in the brain: potential role of the thiol antioxidant N-acetylcysteine amide

artículo científico publicado en 2010

HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells

artículo científico publicado en 2005

HIV-1-induced production of endothelin-1 in an in vitro model of the human blood-brain barrier

artículo científico publicado en 2002

High glucose-induced mitochondrial respiration and reactive oxygen species in mouse cerebral pericytes is reversed by pharmacological inhibition of mitochondrial carbonic anhydrases: Implications for cerebral microvascular disease in diabetes

artículo científico publicado en 2013

Highly active antiretroviral therapy drug combination induces oxidative stress and mitochondrial dysfunction in immortalized human blood-brain barrier endothelial cells

artículo científico publicado en 2010

Human immunodeficiency virus type 1 transport across the in vitro mouse brain endothelial cell monolayer

artículo científico publicado en 2005

Human immunodeficiency virus-1 uses the mannose-6-phosphate receptor to cross the blood-brain barrier

artículo científico publicado en 2012

Human interleukin (IL) 1 alpha, murine IL-1 alpha and murine IL-1 beta are transported from blood to brain in the mouse by a shared saturable mechanism ⬇️

artículo científico publicado el 1 de diciembre de 1991

Human interleukin-1 alpha crosses the blood-testis barriers of the mouse ⬇️

artículo científico publicado el 1 de mayo de 1992

Hyperhomocysteinemic mice show cognitive impairment without features of Alzheimer's disease phenotype.

artículo científico publicado en 2013

Immunotherapy and neuroimmunology in Alzheimer's disease: a perspective from the blood-brain barrier

artículo científico publicado en 2010

Impaired transport of leptin across the blood-brain barrier in obesity

scientific article published on 01 November 1999

Impaired transport of leptin across the blood-brain barrier in obesity is acquired and reversible

artículo científico publicado en 2003

Impairments in brain-to-blood transport of amyloid-β and reabsorption of cerebrospinal fluid in an animal model of Alzheimer's disease are reversed by antisense directed against amyloid-β protein precursor

artículo científico publicado en 2011

In vitro methods in the study of viral and prion permeability across the blood-brain barrier

artículo científico publicado en 2005

In vitro modeling of blood-brain barrier and interface functions in neuroimmune communication

artículo científico publicado en 2020

Increase in presenilin 1 (PS1) levels in senescence-accelerated mice (SAMP8) may indirectly impair memory by affecting amyloid precursor protein (APP) processing

artículo científico publicado en 2009

Increased Hyaluronan and TSG-6 in Association with Neuropathologic Changes of Alzheimer's Disease

artículo científico publicado en 2019

Inflammation-induced dysfunction of the low-density lipoprotein receptor-related protein-1 at the blood-brain barrier: protection by the antioxidant N-acetylcysteine

artículo científico publicado en 2012

Influence of ethanol dependence and methionine enkephalin antisense on serum endomorphin-1 and methionine enkephalin levels

artículo científico publicado en 2004

Inhibition of the brain to blood transport system for enkephalins and Tyr-MIF-1 in mice addicted or genetically predisposed to drinking ethanol

artículo científico publicado en 1989

Initial fate of prions upon peripheral infection: half‐life, distribution, clearance, and tissue uptake ⬇️

artículo científico publicado el 9 de mayo de 2011

Insulin BBB pharmacokinetics in young apoE male and female transgenic mice

artículo científico publicado en 2020

Insulin detemir is not transported across the blood–brain barrier ⬇️

artículo científico publicado el 22 de septiembre de 2010

Insulin resistance, dyslipidemia, and apolipoprotein E interactions as mechanisms in cognitive impairment and Alzheimer's disease

artículo científico publicado en 2016

Insulin transport across the blood-brain barrier can occur independently of the insulin receptor

scientific article published on 28 August 2018

Inter-alpha inhibitor proteins attenuate lipopolysaccharide-induced blood-brain barrier disruption and downregulate circulating interleukin 6 in mice

scientific article published on 24 June 2019

Interactions between the blood-brain barrier and endogenous peptides: emerging clinical implications

artículo científico publicado en 1988

Interactions of β‐Amyloids with the Blood–Brain Barrier ⬇️

artículo científico publicado el 26 de septiembre de 1997

Interleukin-1β transfer across the blood-brain barrier in the ovine fetus

artículo científico publicado en 2015

Interleukin-2 does not cross the blood-brain barrier by a saturable transport system

artículo científico publicado en 1994

Intranasal Delivery of Proteins and Peptides in the Treatment of Neurodegenerative Diseases

artículo científico publicado en 2015

Intranasal Insulin Transport is Preserved in Aged SAMP8 Mice and is Altered by Albumin and Insulin Receptor Inhibition

artículo científico publicado en 2017

Intranasal administration as a route for drug delivery to the brain: evidence for a unique pathway for albumin

artículo científico publicado en 2014

Intranasal administration of PACAP: uptake by brain and regional brain targeting with cyclodextrins

artículo científico publicado en 2012

Intranasal delivery of N-terminal modified leptin-pluronic conjugate for treatment of obesity

artículo científico publicado en 2017

Intravenous human interleukin-1alpha impairs memory processing in mice: dependence on blood-brain barrier transport into posterior division of the septum

artículo científico publicado en 2001

Is obesity a disease of the blood-brain barrier? Physiological, pathological, and evolutionary considerations

artículo científico publicado en 2003

Ischemia-reperfusion impairs blood-brain barrier function and alters tight junction protein expression in the ovine fetus

artículo científico publicado en 2012

Isolation of peptide transport system-6 from brain endothelial cells: therapeutic effects with antisense inhibition in Alzheimer and stroke models

artículo científico publicado en 2008

Lack of saturable transport across the blood-brain barrier in either direction for beta-amyloid1-28 (Alzheimer's disease protein).

artículo científico publicado en 1991

Leptin and adiponectin levels in middle-aged postmenopausal women: associations with lifestyle habits, hormones, and inflammatory markers--a cross-sectional study

scientific article published on 01 December 2006

Leptin enters the brain by a saturable system independent of insulin

artículo científico publicado en 1996

Leptin transport across the blood-brain barrier of the Koletsky rat is not mediated by a product of the leptin receptor gene

artículo científico publicado en 2002

Leptin transport across the blood-brain barrier: implications for the cause and treatment of obesity

artículo científico publicado en 2001

Leucine Modulates Peptide Transport System-1 Across the Blood-brain Barrier at a Stereospecific Site within the Central Nervous System ⬇️

artículo científico publicado el 1 de abril de 1991

Leucine competes with kynurenine for blood-to-brain transport and prevents lipopolysaccharide-induced depression-like behavior in mice

scientific article published on 09 July 2018

Lipids and cognition

artículo científico publicado en 2010

Lipopolysaccharide alters the blood-brain barrier transport of amyloid beta protein: a mechanism for inflammation in the progression of Alzheimer's disease

artículo científico publicado en 2009

Lipopolysaccharide impairs amyloid β efflux from brain: altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood-brain barrier

artículo científico publicado en 2012

Lipopolysaccharide impairs blood-brain barrier P-glycoprotein function in mice through prostaglandin- and nitric oxide-independent pathways

artículo científico publicado en 2008

Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF.

artículo científico publicado en 2011

Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by the p38 mitogen-activated protein kinase pathway

artículo científico publicado en 2008

Loss of appendicular muscle mass and loss of muscle strength in young postmenopausal women

artículo científico publicado en 2007

Macrophage exosomes as natural nanocarriers for protein delivery to inflamed brain.

artículo científico publicado en 2017

Mannose 6-phosphate receptor-mediated transport of sulfamidase across the blood-brain barrier in the newborn mouse

artículo científico publicado en 2008

Measurement of efflux rates from brain to blood

artículo científico publicado en 1997

Measurement of phosphorothioate oligodeoxynucleotide antisense transport across the blood-brain barrier

artículo científico publicado en 2011

Mechanisms of HIV type 1-induced cognitive impairment: evidence for hippocampal cholinergic involvement with overstimulation of the VIPergic system by the viral coat protein core

artículo científico publicado en 2002

Mediation of serotonin-induced analgesia by the 5HT2 receptor in the pentobarbital anesthetized mouse model

artículo científico publicado en 1988

Memories are made of this: recent advances in understanding cognitive impairments and dementia

scientific article published on 01 April 2003

Microvasculature of the Mouse Cerebral Cortex Exhibits Increased Accumulation and Synthesis of Hyaluronan With Aging

artículo científico publicado en 2017

Minimal penetration of lipopolysaccharide across the murine blood-brain barrier

artículo científico publicado en 2009

Minireview. Brain peptides: the dangers of constricted nomenclatures

artículo científico publicado en 1983

Misleading concepts in the field of brain peptides ⬇️

artículo científico publicado el 1 de enero de 1984

Modest Blood-Brain Barrier Permeability of the Cyclodextrin Kleptose: Modification by Efflux and Luminal Surface Binding

artículo científico publicado en 2019

Modulation of immunoactive levels of DSIP and blood-brain permeability by lighting and diurnal rhythm

artículo científico publicado en 1985

Modulation of the carrier-mediated transport of the Tyr-MIF-1 across the blood-brain barrier by essential amino acids

artículo científico publicado en 1986

Modulators of IgG penetration through the blood-brain barrier: Implications for Alzheimer's disease immunotherapy

artículo científico publicado en 2016

Molecular Mechanisms of Intranasal Insulin in SAMP8 Mice

artículo científico publicado en 2019

Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury

artículo científico publicado en 2014

Mouse models of neurological disorders: a view from the blood-brain barrier

artículo científico publicado en 2009

Multiple lipopolysaccharide (LPS) injections alter interleukin 6 (IL-6), IL-7, IL-10 and IL-6 and IL-7 receptor mRNA in CNS and spleen

artículo científico publicado en 2017

N-Acetylcysteine amide protects against methamphetamine-induced oxidative stress and neurotoxicity in immortalized human brain endothelial cells

artículo científico publicado en 2009

Nano-particle delivery of brain derived neurotrophic factor after focal cerebral ischemia reduces tissue injury and enhances behavioral recovery.

artículo científico publicado en 2016

Nanoformulation of Brain-Derived Neurotrophic Factor with Target Receptor-Triggered-Release in the Central Nervous System

artículo científico publicado en 2017

Neuroimmune Axes of the Blood-Brain Barriers and Blood-Brain Interfaces: Bases for Physiological Regulation, Disease States, and Pharmacological Interventions.

artículo científico publicado en 2018

Neuroinflammation: a common pathway in CNS diseases as mediated at the blood-brain barrier

artículo científico publicado en 2012

Neurovascular unit crosstalk: Pericytes and astrocytes modify cytokine secretion patterns of brain endothelial cells.

artículo científico publicado en 2017

Neutralizing anti-interleukin-1β antibodies modulate fetal blood-brain barrier function after ischemia

artículo científico publicado en 2014

Nitrative stress in cerebral endothelium is mediated by mGluR5 in hyperhomocysteinemia

artículo científico publicado en 2011

Nitric oxide activity and isoenzyme expression in the senescence-accelerated mouse p8 model of Alzheimer's disease: effects of anti-amyloid antibody and antisense treatments

artículo científico publicado en 2009

Nitric oxide is a central component in neuropeptide regulation of appetite ⬇️

artículo científico publicado el 22 de enero de 2011

Nitric oxide isoenzymes regulate lipopolysaccharide-enhanced insulin transport across the blood-brain barrier.

artículo científico publicado en 2008

Novel concepts from novel peptides

artículo científico publicado en 1994

Obesity and hypertriglyceridemia produce cognitive impairment

artículo científico publicado en 2008

Obesity-inducing lesions of the central nervous system alter leptin uptake by the blood-brain barrier

artículo científico publicado en 2001

Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling before obesity onset

artículo científico publicado en 2003

Ocular Delivery of PACAP1-27 Protects the Retina From Ischemic Damage in Rodents

artículo científico publicado en 2016

Opiate modulation of IL-1alpha, IL-2, and TNF-alpha transport across the blood-brain barrier

artículo científico publicado en 2008

Opposite direction of transport across the blood-brain barrier for Tyr-MIF-1 and MIF-1: comparison with morphine

artículo científico publicado en 1994

Orally administered cyclo(His-Pro) reduces ethanol-induced narcosis in mice

artículo científico publicado el 1 de noviembre de 1992

Orexin-A-induced feeding is dependent on nitric oxide

artículo científico publicado en 2005

Ovine proinflammatory cytokines cross the murine blood-brain barrier by a common saturable transport mechanism

artículo científico publicado en 2010

Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: Implications for Aβ accumulation in AD brain ⬇️

artículo científico publicado el 7 de octubre de 2010

Paclitaxel Reduces Brain Injury from Repeated Head Trauma in Mice

scientific article published on 01 January 2019

Passage of amyloid beta protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease

artículo científico publicado en 2002

Passage of cytokines across the blood-brain barrier

artículo científico publicado en 1995

Passage of erythropoietic agents across the blood-brain barrier: a comparison of human and murine erythropoietin and the analog darbepoetin alfa

artículo científico publicado en 2004

Passage of human amyloid beta-protein 1-40 across the murine blood-brain barrier

artículo científico publicado en 1994

Passage of leptin across the blood-testis barrier

artículo científico publicado en 1999

Passage of murine scrapie prion protein across the mouse vascular blood-brain barrier

artículo científico publicado en 2004

Passage of peptides across the blood-brain barrier: pathophysiological perspectives

artículo científico publicado en 1996

Passage of pituitary adenylate cyclase activating polypeptide1-27 and pituitary adenylate cyclase activating polypeptide1-38 across the blood-brain barrier.

artículo científico publicado en 1993

Passage of vasoactive intestinal peptide across the blood–brain barrier ⬇️

artículo científico publicado el 1 de marzo de 2003

Passage through the Ocular Barriers and Beneficial Effects in Retinal Ischemia of Topical Application of PACAP1-38 in Rodents.

artículo científico publicado en 2017

Pegylated leptin antagonist is a potent orexigenic agent: preparation and mechanism of activity

artículo científico publicado en 2009

Penetration of interleukin-6 across the murine blood-brain barrier

artículo científico publicado en 1994

Peptide transport system-1 (PTS-1) for Tyr-MIF-1 and Met-enkephalin differs from the receptors for either

artículo científico publicado en 1999

Peptide transport systems for opiates across the blood-brain barrier

artículo científico

Peptides and the blood-brain barrier

artículo científico

Peptides and the blood-brain barrier: lipophilicity as a predictor of permeability

artículo científico publicado en 1985

Peptides and the senescent blood-brain barrier ⬇️

artículo científico publicado el 1 de enero de 1988

Peptides crossing the blood-brain barrier: some unusual observations

artículo científico publicado en 1999

Pericytes Suppress Brain Metastasis from Lung Cancer In Vitro

artículo científico publicado en 2019

Perinatal treatment of rats with opiates affects the development of the blood-brain barrier transport system PTS-1.

artículo científico publicado en 1996

Peripheral administration of antisense oligonucleotides targeting the amyloid-β protein precursor reverses AβPP and LRP-1 overexpression in the aged SAMP8 mouse brain

artículo científico publicado en 2012

Permanent and temporary inactivation of the hippocampus impairs T-maze footshock avoidance acquisition and retention

artículo científico publicado en 2000

Permeability of the blood-brain and blood-spinal cord barriers to interferons

artículo científico publicado en 1997

Permeability of the blood-brain barrier to HIV-1 Tat.

artículo científico publicado en 2005

Permeability of the blood-brain barrier to a novel satiety molecule nesfatin-1

artículo científico publicado en 2007

Permeability of the blood-brain barrier to a rhenacarborane

artículo científico publicado en 2009

Permeability of the blood-brain barrier to albumin and insulin in the young and aged SAMP8 mouse

artículo científico publicado en 2000

Permeability of the blood-brain barrier to melanocortins

artículo científico publicado en 1995

Permeability of the blood-brain barrier to neuropeptides: the case for penetration

artículo científico publicado en 1985

Permeability of the blood-brain barrier to neurotrophins

artículo científico publicado en 1998

Permeability of the blood-brain barrier to peptides: an approach to the development of therapeutically useful analogs.

artículo científico publicado en 1992

Permeability of the blood-brain barrier to the neurotensin8-13 analog NT1.

artículo científico publicado en 1995

Permeability of the mouse blood-brain barrier to murine interleukin-2: predominance of a saturable efflux system

artículo científico publicado en 2004

Peroxisome proliferator-activated receptor-gamma-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status

artículo científico publicado en 2008

Persistence of blood-to-brain transport of leptin in obese leptin-deficient and leptin receptor-deficient mice

artículo científico

Pharmacokinetics and modeling of immune cell trafficking: quantifying differential influences of target tissues versus lymphocytes in SJL and lipopolysaccharide-treated mice

artículo científico publicado en 2012

Pharmacologic manipulation of lysosomal enzyme transport across the blood-brain barrier

artículo científico publicado en 2015

Pharmacological inhibition of mitochondrial carbonic anhydrases protects mouse cerebral pericytes from high glucose-induced oxidative stress and apoptosis.

artículo científico publicado en 2012

Pharmacological profiles of peptide drug candidates for the treatment of Alzheimer's disease

artículo científico publicado en 2003

Physiological consequences of the passage of peptides across the blood-brain barrier

artículo científico publicado en 1993

Physiology and pathology of the blood-brain barrier: implications for microbial pathogenesis, drug delivery and neurodegenerative disorders

artículo científico publicado en 1999

Pituitary adenylate cyclase activating polypeptide (PACAP) can cross the vascular component of the blood-testis barrier in the mouse.

artículo científico publicado en 1993

Pituitary adenylate cyclase-activating polypeptide enhances saliva secretion via direct binding to PACAP receptors of major salivary glands in mice

artículo científico publicado en 2016

Pituitary adenylate cyclase-activating polypeptide: Protective effects in stroke and dementia

artículo científico publicado en 2020

Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson's disease.

artículo científico publicado en 2014

Pluronic modified leptin with increased systemic circulation, brain uptake and efficacy for treatment of obesity

artículo científico publicado en 2014

Polypeptide point modifications with fatty acid and amphiphilic block copolymers for enhanced brain delivery

artículo científico publicado en 2005

Possible therapeutic implications of the effects of some peptides on the brain.

artículo científico publicado en 1987

Potentiation of lead-induced cell death in PC12 cells by glutamate: protection by N-acetylcysteine amide (NACA), a novel thiol antioxidant

artículo científico publicado en 2006

Predictors of serum testosterone and DHEAS in African-American men.

artículo científico publicado en 2008

Preproenkephalin targeted antisenses cross the blood-brain barrier to reduce brain methionine enkephalin levels and increase voluntary ethanol drinking

artículo científico publicado en 2005

Prevention of ischemia-induced death of hippocampal neurons by pituitary adenylate cyclase activating polypeptide

artículo científico publicado en 1996

Primary adrenal hyperplasia: a new subset of primary hyperaldosteronism

scientific article published on 01 May 1984

Protective effects of an anti-melanocortin-4 receptor scFv derivative in lipopolysaccharide-induced cachexia in rats

artículo científico publicado en 2012

Protein conjugation with amphiphilic block copolymers for enhanced cellular delivery.

artículo científico publicado en 2008

Proteomic analysis of specific brain proteins in aged SAMP8 mice treated with alpha-lipoic acid: implications for aging and age-related neurodegenerative disorders

artículo científico publicado en 2005

Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Abeta region of amyloid precursor protein

artículo científico publicado en 2005

Quantitative analysis of chondroitin sulfate disaccharides from human and rodent fixed brain tissue by electrospray ionization-tandem mass spectrometry

artículo científico publicado en 2019

Radioimmunoassay of DSIP-like material in human blood: possible protein binding

artículo científico publicado en 1981

Rapid transport of CCL11 across the blood-brain barrier: regional variation and importance of blood cells

artículo científico publicado en 2014

Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a beta-sheet breaker peptide

artículo científico publicado en 2002

Regional differences in PACAP transport across the blood-brain barrier in mice: a possible influence of strain, amyloid beta protein, and age.

artículo científico publicado en 2002

Regional differences in the metabolism of Tyr-MIF-1 and Tyr-W-MIF-1 by rat brain mitochondria ⬇️

artículo científico publicado el 1 de enero de 1998

Regional transport of TNF-alpha across the blood-brain barrier in young ICR and young and aged SAMP8 mice

artículo científico publicado en 2001

Regional variation in transport of pancreatic polypeptide across the blood-brain barrier of mice.

artículo científico publicado en 1995

Regional variations in the transport of interleukin-1alpha across the blood-brain barrier in ICR and aging SAMP8 mice

artículo científico publicado en 2000

Relative contributions of a CVO and the microvascular bed to delivery of blood-borne IL-1alpha to the brain

artículo científico publicado en 1998

Relative contributions of peripheral and central sources to levels of IL-1α in the cerebral cortex of mice: assessment with species-specific enzyme immunoassays ⬇️

artículo científico publicado el 1 de octubre de 1997

Release of cytokines by brain endothelial cells: A polarized response to lipopolysaccharide

artículo científico publicado en 2005

Resistance to the sympathoexcitatory effects of insulin and leptin in late pregnant rats

artículo científico publicado en 2019

Retro-inverso prosaptide peptides retain bioactivity, are stable In vivo, and are blood-brain barrier permeable.

artículo científico publicado en 2000

Reversible association of the cytokines MIP-1 alpha and MIP-1 beta with the endothelia of the blood-brain barrier

artículo científico publicado en 1996

Role of the Blood-Brain Barrier in Central Nervous System Insulin Resistance

scientific article published on 04 June 2019

Role of the blood-brain barrier in the evolution of feeding and cognition ⬇️

artículo científico publicado en 2012

Routes for the delivery of insulin to the central nervous system: A comparative review

artículo científico publicado en 2018

SAMP8 mice have altered hippocampal gene expression in long term potentiation, phosphatidylinositol signaling, and endocytosis pathways

scientific article published on 19 August 2013

Saturable efflux of the peptides RC-160 and Tyr-MIF-1 by different parts of the blood-brain barrier

artículo científico publicado en 1994

Saturable transport of peptides across the blood-brain barrier

artículo científico publicado en 1987

Saturable transport of the neurokinin-1 non-peptide antagonist LY303870 across the rat blood-brain barrier after intravenous administration

artículo científico publicado en 2001

Selective transport across the blood-brain barrier

artículo científico publicado en 1986

Selective uptake of the somatostatin analog RC-160 across the blood-brain tumor barrier of mice with KHT sarcomas

artículo científico publicado el 1 de octubre de 1992

Sequestration of centrally administered insulin by the brain: effects of starvation, aluminum, and TNF-alpha

artículo científico publicado en 1996

Serum amyloid A: an ozone-induced circulating factor with potentially important functions in the lung-brain axis

artículo científico publicado en 2017

Site-directed antisense oligonucleotide decreases the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice

artículo científico publicado en 2000

Sleep fragmentation and sepsis differentially impact blood-brain barrier integrity and transport of tumor necrosis factor-α in aging

artículo científico publicado en 2015

Soluble interleukin-6 receptor induces motor stereotypies and co-localizes with gp130 in regions linked to cortico-striato-thalamo-cortical circuits

artículo científico publicado en 2012

Somatostatin receptor subtype-4 agonist NNC 26-9100 decreases extracellular and intracellular Aβ₁₋₄₂ trimers

artículo científico publicado en 2012

Somatostatin receptor subtype-4 agonist NNC 26-9100 mitigates the effect of soluble Aβ(42) oligomers via a metalloproteinase-dependent mechanism

artículo científico publicado en 2013

Starvation and triglycerides reverse the obesity-induced impairment of insulin transport at the blood-brain barrier

artículo científico publicado en 2008

Stereospecific transport of Tyr-MIF-1 across the blood-brain barrier by peptide transport system-1.

artículo científico publicado en 1990

Studies of the slow bidirectional transport of iron and transferrin across the blood-brain barrier

artículo científico publicado en 1988

Study of passage of peptides across the blood-brain barrier: biological effects of cyclo(His-Pro) after intravenous and oral administration

artículo científico publicado en 1994

Susceptibility of juvenile and adult blood-brain barrier to endothelin-1: regulation of P-glycoprotein and breast cancer resistance protein expression and transport activity

artículo científico publicado en 2012

Tau Proteins Cross the Blood-Brain Barrier

artículo científico publicado en 2016

Telmisartan prevents diet-induced obesity and preserves leptin transport across the blood-brain barrier in high-fat diet-fed mice

artículo científico publicado en 2018

Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition

artículo científico publicado en 2009

The APOE genotype: modification of therapeutic responses in Alzheimer's disease

artículo científico publicado en 2015

The Blood-Brain Barrier Interface in Diabetes Mellitus: Dysfunctions, Mechanisms, and Approaches to Treatment

scientific article published on 25 March 2020

The Effects of Normal Aging on Regional Accumulation of Hyaluronan and Chondroitin Sulfate Proteoglycans in the Mouse Brain

artículo científico publicado en 2018

The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice

artículo científico publicado en 2003

The blood-brain barrier and immune function and dysfunction

artículo científico publicado en 2009

The blood-brain barrier as a cause of disease

artículo científico publicado en 2008

The blood-brain barrier as a cause of obesity

artículo científico publicado en 2008

The blood-brain barrier as a regulatory interface in the gut-brain axes

artículo científico publicado en 2006

The blood-brain barrier as an endocrine tissue

artículo científico publicado en 2019

The blood-brain barrier in neuroimmunology: Tales of separation and assimilation

artículo científico publicado en 2014

The blood-brain barrier in psychoneuroimmunology

artículo científico publicado en 2006

The blood-brain barrier in psychoneuroimmunology

artículo científico publicado en 2009

The blood-brain barrier: connecting the gut and the brain

scientific article published on 07 April 2008

The blood-brain barrier: methods for the study of peptide transport mechanisms. Introduction to Part II

scientific article published on 01 October 1994

The dam breaks: disruption of the blood-brain barrier in diabetes mellitus

artículo científico publicado en 2006

The effect of cardiac arrest on the blood-testis barrier to albumin, tumor necrosis factor-alpha, pituitary adenylate cyclase activating polypeptide, sucrose, and verapamil in the mouse

artículo científico publicado en 2001

The effect of cardiac arrest on the permeability of the mouse blood-brain and blood-spinal cord barriers to PACAP.

artículo científico publicado en 2000

The effects of high fat diets on the blood-brain barrier transport of leptin: failure or adaptation?

artículo científico publicado en 2006

The extracellular matrix of the blood-brain barrier: structural and functional roles in health, aging, and Alzheimer's disease

artículo científico publicado en 2019

The general anesthesia induced by various drugs differentially affects analgesia and its variability

artículo científico publicado en 1988

The history of neuropeptide research: version 5.a.

artículo científico publicado en 1996

The interleukins-1 alpha, -1 beta, and -2 do not acutely disrupt the murine blood-brain barrier

artículo científico publicado el 1 de mayo de 1992

The neurotrophins and their receptors: structure, function, and neuropathology

artículo científico publicado en 1994

The opiate system in invertebrates

artículo científico publicado en 1994

The putative blood-brain barrier transporter for the beta-amyloid binding protein apolipoprotein j is saturated at physiological concentrations

artículo científico publicado en 1997

The role of the blood-brain barrier transporter PTS-1 in regulating concentrations of methionine enkephalin in blood and brain

artículo científico publicado en 1997

The transport mechanism of extracellular vesicles at the blood-brain barrier

artículo científico publicado en 2017

Topiramate Protects Pericytes from Glucotoxicity: Role for Mitochondrial CA VA in Cerebromicrovascular Disease in Diabetes.

artículo científico publicado en 2015

Topiramate treatment protects blood-brain barrier pericytes from hyperglycemia-induced oxidative damage in diabetic mice

artículo científico publicado en 2011

Transmission of α-synuclein-containing erythrocyte-derived extracellular vesicles across the blood-brain barrier via adsorptive mediated transcytosis: another mechanism for initiation and progression of Parkinson's disease?

artículo científico publicado en 2017

Transmission routes of HIV-1 gp120 from brain to lymphoid tissues

artículo científico publicado en 1999

Transport across the blood-brain barrier of pluronic leptin.

artículo científico publicado en 2010

Transport of CRH from mouse brain directly affects peripheral production of β-endorphin by the spleen ⬇️

artículo científico publicado el 1 de diciembre de 1997

Transport of an antifungal trypsin inhibitor isolated from corn across the blood-brain barrier

artículo científico publicado en 2002

Transport of antisense across the blood-brain barrier.

artículo científico publicado en 2005

Transport of brain-derived neurotrophic factor across the blood-brain barrier

artículo científico publicado en 1998

Transport of human immunodeficiency virus type 1 pseudoviruses across the blood-brain barrier: role of envelope proteins and adsorptive endocytosis

artículo científico publicado en 2001

Transport of pituitary adenylate cyclase-activating polypeptide across the blood-brain barrier and the prevention of ischemia-induced death of hippocampal neurons.

artículo científico publicado en 1996

Transport of prion protein across the blood-brain barrier

artículo científico publicado en 2009

Transport of thyroxine across the blood-brain barrier is directed primarily from brain to blood in the mouse

artículo científico publicado en 1985

Transport, uptake, and metabolism of blood-borne vasopressin by the blood-brain barrier

artículo científico publicado el 11 de septiembre de 1992

Triglycerides cross the blood-brain barrier and induce central leptin and insulin receptor resistance

artículo científico publicado en 2017

Triglycerides induce leptin resistance at the blood-brain barrier

artículo científico publicado en 2004

Tumor Necrosis Factor-α: a Neuromodulator in the CNS ⬇️

artículo científico publicado el 1 de septiembre de 1997

Twenty-one hormones fail to inhibit the brain to blood transport system for Tyr-MIF-1 and the enkephalins in mice

artículo científico publicado en 1988

Tyr-MIF-1 and Met-enkephalin share a saturable blood-brain barrier transport system

artículo científico publicado en 1987

Unidirectional specific and modulated brain to blood transport of corticotropin-releasing hormone

artículo científico publicado en 1996

Uptake and degradation of blood-borne insulin by the olfactory bulb

artículo científico publicado en 1999

Uptake of peptides containing Tyr-Pro by human and mouse erythrocytes

artículo científico publicado en 1990

Uptake, content, regulation of plasma concentrations, and binding of Tyr-MIF-1 by the adrenals

artículo científico publicado en 1993

Withdrawal from alcohol in withdrawal seizure-prone and -resistant mice: evidence for enkephalin resistance

artículo científico publicado en 2001

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