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A Runx2 threshold for the cleidocranial dysplasia phenotype

artículo científico publicado en 2008

Alterations in intranuclear localization of Runx2 affect biological activity

artículo científico publicado en 2006

Analysis of in vivo gene expression using epitope-tagged proteins

artículo científico publicado en 2004

Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility

artículo científico publicado en 2010

Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts

artículo científico publicado el 1 de septiembre de 2003

Chromatin immunoprecipitation

scientific article published on 01 January 2004

Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.

artículo científico publicado en 2008

Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer

artículo científico publicado en 2005

Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression

artículo científico publicado en 2009

Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer

scientific article published on August 2008

Immunofluorescence analysis using epitope-tagged proteins: in vitro system

scientific article published on 01 January 2004

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

artículo científico publicado en 2005

In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling

artículo científico publicado en 2004

In situ immunofluorescence analysis: immunofluorescence microscopy

scientific article published on 01 January 2004

Intranuclear Trafficking: Organization and Assembly of Regulatory Machinery for Combinatorial Biological Control

artículo científico publicado en 2004

Intranuclear organization of RUNX transcriptional regulatory machinery in biological control of skeletogenesis and cancer

artículo científico publicado en 2003

Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.

artículo científico publicado en 2003

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.

artículo científico publicado en 2007

Nuclear microenvironments in biological control and cancer.

artículo científico publicado en 2007

Nuclear microenvironments support physiological control of gene expression

artículo científico publicado en 2003

Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer

artículo científico publicado en 2007

Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer

artículo científico publicado en 2009

Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development

scientific journal article

Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.

artículo científico publicado en 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay

scientific article published on 01 January 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction

artículo científico publicado en 2004

Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation

artículo científico publicado en 2007

Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.

artículo científico publicado en 2007

Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors

artículo científico publicado en 2008

Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells

scientific article published on October 2008

SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation

scientific journal article

Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription.

artículo científico publicado en 2005

Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation.

artículo científico publicado en 2008

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

artículo científico publicado en 2008

The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion

artículo científico publicado en 2005

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation

artículo científico publicado en 2015

The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts

artículo científico publicado en 2005

The dynamic organization of gene-regulatory machinery in nuclear microenvironments

artículo científico publicado en 2005

The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss

artículo científico publicado en 2010

The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes

artículo científico publicado en 2010

The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts

artículo científico publicado en 2009

The role of Runx2 in facilitating autophagy in metastatic breast cancer cells

artículo científico publicado en 2017

Transcription-factor-mediated epigenetic control of cell fate and lineage commitment

scientific article published on February 2009

hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3.

artículo científico publicado en 2014