Filtros de búsqueda

Lista de obras de

"S'ils n'ont pas de pain, qu'ils mangent de la brioche." Focus on "anaerobic respiration sustains mitochondrial membrane potential in a prolyl hydroxylase pathway-activated cancer cell line in a hypoxic microenvironment".

artículo científico publicado en 2013

(+)-Grandifloracin, an antiausterity agent, induces autophagic PANC-1 pancreatic cancer cell death

artículo científico publicado en 2013

5-amino-4-imidazolecarboxamide riboside confers strong tolerance to glucose starvation in a 5'-AMP-activated protein kinase-dependent fashion

artículo científico publicado en 2002

A pull-down assay for 5' AMP-activated protein kinase activity using the GST-fused protein

artículo científico publicado en 2006

ARK5 expression in colorectal cancer and its implications for tumor progression

artículo científico publicado en 2004

ARK5 is a tumor invasion-associated factor downstream of Akt signaling

artículo científico publicado en 2004

ARK5 is transcriptionally regulated by the Large-MAF family and mediates IGF-1-induced cell invasion in multiple myeloma: ARK5 as a new molecular determinant of malignant multiple myeloma

artículo científico publicado en 2005

ARK5 suppresses the cell death induced by nutrient starvation and death receptors via inhibition of caspase 8 activation, but not by chemotherapeutic agents or UV irradiation

artículo científico publicado en 2003

Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines

artículo científico publicado en 2014

An anticancer agent, pyrvinium pamoate inhibits the NADH–fumarate reductase system—a unique mitochondrial energy metabolism in tumour microenvironments

artículo científico publicado en 2012

Analysis of promoter region of X-linked pgk-1 gene polymorphisms: evidence for polyclonality of adult mouse gastric glands.

artículo científico publicado en 2004

Angelmarin, a novel anti-cancer agent able to eliminate the tolerance of cancer cells to nutrient starvation

artículo científico publicado en 2005

Antiausterity activity of arctigenin enantiomers: importance of (2R,3R)-absolute configuration

artículo científico publicado en 2014

Antitumor activity of pyrvinium pamoate, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-quinolinium pamoate salt, showing preferential cytotoxicity during glucose starvation

artículo científico publicado en 2004

Antitumor effect of kigamicin D on mouse tumor models.

artículo científico publicado en 2006

Arctigenin inhibits osteoclast differentiation and function by suppressing both calcineurin-dependent and osteoblastic cell-dependent NFATc1 pathways

artículo científico publicado en 2014

Association between aldehyde dehydrogenase gene polymorphisms and the phenomenon of field cancerization in patients with head and neck cancer

artículo científico publicado en 2002

Autophagy and cancer: dynamism of the metabolism of tumor cells and tissues

artículo científico publicado en 2008

Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation

artículo científico publicado en 2007

Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome

artículo científico

Biased discordance of KRAS mutation detection in archived colorectal cancer specimens between the ARMS-Scorpion method and direct sequencing

artículo científico publicado en 2010

Bioactive secondary metabolites from Boesenbergia pandurata of Myanmar and their preferential cytotoxicity against human pancreatic cancer PANC-1 cell line in nutrient-deprived medium.

artículo científico publicado en 2007

Change in plasma lactate concentration during arctigenin administration in a phase I clinical trial in patients with gemcitabine-refractory pancreatic cancer.

artículo científico publicado en 2018

Characterization of cancer omics and drug perturbations in panels of lung cancer cells

artículo científico publicado en 2019

Chemical Constituents of Mangifera indica and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line.

artículo científico publicado en 2016

Chemical constituents of propolis from Myanmar and their preferential cytotoxicity against a human pancreatic cancer cell line

artículo científico publicado en 2009

Chemopreventive effect of peroxisome proliferator-activated receptor gamma on gastric carcinogenesis in mice

artículo científico publicado en 2005

Clinical significance of BRAF non-V600E mutations on the therapeutic effects of anti-EGFR monoclonal antibody treatment in patients with pretreated metastatic colorectal cancer: the Biomarker Research for anti-EGFR monoclonal Antibodies by Comprehen

artículo científico publicado en 2017

Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress.

artículo científico publicado en 2018

Constituents of Brazilian red propolis and their preferential cytotoxic activity against human pancreatic PANC-1 cancer cell line in nutrient-deprived condition.

artículo científico publicado en 2007

Constituents of the Rhizomes of Boesenbergia pandurata and Their Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Line

artículo científico publicado en 2017

Critical role of H2O2 generated by NOX4 during cellular response under glucose deprivation

artículo científico publicado en 2013

Critical roles of AMP-activated protein kinase in constitutive tolerance of cancer cells to nutrient deprivation and tumor formation

artículo científico publicado en 2002

Cytotoxic constituents of Soymida febrifuga from Myanmar.

artículo científico publicado en 2009

Development of Highly Selective Fluorescent Probe Enabling Flow-Cytometric Isolation of ALDH3A1-Positive Viable Cells.

artículo científico publicado en 2016

Differential regulation of tumor angiogenesis by distinct ErbB homo- and heterodimers

artículo científico publicado en 2002

Diterpenes from "Pini Resina" and their preferential cytotoxic activity under nutrient-deprived condition

artículo científico publicado en 2006

Effect of a poly(ADP-ribose) polymerase-1 inhibitor against esophageal squamous cell carcinoma cell lines

artículo científico publicado en 2013

Effects of nitric oxide donors on vascular endothelial growth factor gene induction.

artículo científico publicado en 2002

Epidermal growth factor receptor (EGFR) signaling regulates global metabolic pathways in EGFR-mutated lung adenocarcinoma

artículo científico publicado en 2014

Expression and hypoxia-responsiveness of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 in mammary gland malignant cell lines.

artículo científico publicado en 2005

Feasibility and robustness of amplification refractory mutation system (ARMS)-based KRAS testing using clinically available formalin-fixed, paraffin-embedded samples of colorectal cancers

artículo científico publicado en 2010

Genome-wide identification and annotation of HIF-1α binding sites in two cell lines using massively parallel sequencing

artículo científico publicado en 2010

Highly oxygenated antiausterity agents from the leaves of Uvaria dac.

artículo científico publicado en 2017

Histopathological factors affecting the extraction of high quality genomic DNA from tissue sections for next-generation sequencing

artículo científico publicado en 2019

Hypermutation and unique mutational signatures of occupational cholangiocarcinoma in printing workers exposed to haloalkanes

artículo científico publicado en 2016

Hypoglycemic/hypoxic condition in vitro mimicking the tumor microenvironment markedly reduced the efficacy of anticancer drugs

artículo científico publicado en 2011

Hypoxia and nitric oxide treatment confer tolerance to glucose starvation in a 5'-AMP-activated protein kinase-dependent manner

artículo científico publicado en 2002

Hypoxia imaging endoscopy equipped with laser light source from preclinical live animal study to first-in-human subject research

artículo científico publicado en 2014

Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation

artículo científico publicado en 2004

Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers

artículo científico publicado en 2006

IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner

artículo científico publicado en 2004

Identification and characterization of cancer mutations in Japanese lung adenocarcinoma without sequencing of normal tissue counterparts

artículo científico publicado en 2013

Identification of a lung adenocarcinoma cell line with CCDC6-RET fusion gene and the effect of RET inhibitors in vitro and in vivo

artículo científico publicado en 2013

Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein

artículo científico publicado en 2002

Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation

artículo científico publicado en 2006

Identification of chrysoplenetin from Vitex negundo as a potential cytotoxic agent against PANC-1 and a panel of 39 human cancer cell lines (JFCR-39).

artículo científico publicado en 2011

Immunohistochemical expression of inducible nitric oxide synthase (iNOS) in human brain tumors: relationships of iNOS to superoxide dismutase (SOD) proteins (SOD1 and SOD2), Ki-67 antigen (MIB-1) and p53 protein

artículo científico publicado en 2002

Impact of inducible nitric oxide synthase gene on tumor progression

artículo científico publicado en 2009

Improvement of radiation-induced healing delay by etanercept treatment in rat arteries

artículo científico publicado en 2009

Improvement of the breaking strength of wound by combined treatment with recombinant human G-CSF, recombinant human M-CSF, and a TGF-beta1 receptor kinase inhibitor in rat skin

artículo científico publicado en 2008

Inducible nitric oxide synthase activity induced by sodium chloride solution prolongs luminal pH elevation in rat and mouse stomachs

artículo científico publicado en 2003

Induction of cell–cell detachment during glucose starvation through F-actin conversion by SNARK, the fourth member of the AMP-activated protein kinase catalytic subunit family

artículo científico publicado el 7 de noviembre de 2003

Induction of matrix metalloproteinase gene transcription by nitric oxide and mechanisms of MMP-1 gene induction in human melanoma cell lines

artículo científico publicado en 2003

Induction of necrosis in human myeloma cells by kigamicin

artículo científico publicado en 2008

Involvement of transforming growth factor-beta 1 signaling in hypoxia-induced tolerance to glucose starvation

artículo científico publicado en 2005

Kigamicin D, a novel anticancer agent based on a new anti-austerity strategy targeting cancer cells' tolerance to nutrient starvation

artículo científico publicado en 2004

Kigamicins, novel antitumor antibiotics. I. Taxonomy, isolation, physico-chemical properties and biological activities

artículo científico publicado en 2003

Kigamicins, novel antitumor antibiotics. II. Structure determination.

artículo científico publicado en 2003

Loss of HGF activator inhibits foveolar hyperplasia induced by oxyntic atrophy without altering gastrin levels.

artículo científico publicado en 2012

Massive transcriptional start site analysis of human genes in hypoxia cells

artículo científico publicado en 2009

Measurement and verification of positron emitter nuclei generated at each treatment site by target nuclear fragment reactions in proton therapy

scientific article published on 01 August 2010

Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma.

artículo científico publicado en 2018

Metabolomic profiling of lung and prostate tumor tissues by capillary electrophoresis time-of-flight mass spectrometry.

artículo científico publicado en 2012

Mitochondrial fumarate reductase as a target of chemotherapy: from parasites to cancer cells

artículo científico

Mitochondrial inhibitors show preferential cytotoxicity to human pancreatic cancer PANC-1 cells under glucose-deprived conditions.

artículo científico publicado en 2010

Molecular analysis of the TSC1 gene in adenocarcinoma of the lung

artículo científico publicado en 2004

Muscle contractions, AICAR, and insulin cause phosphorylation of an AMPK-related kinase

artículo científico publicado en 2005

Muscle-specific knock-out of NUAK family SNF1-like kinase 1 (NUAK1) prevents high fat diet-induced glucose intolerance

artículo científico publicado en 2012

NDR2 acts as the upstream kinase of ARK5 during insulin-like growth factor-1 signaling

artículo científico publicado en 2006

Nitric oxide as an endogenous mutagen for Sendai virus without antiviral activity

artículo científico publicado en 2004

Non-Hodgkin's lymphoma in a patient with probable hereditary nonpolyposis colon cancer: report of a case and review of the literature

artículo científico publicado en 2002

Novel anticancer agents, kayeassamins A and B from the flower of Kayea assamica of Myanmar.

artículo científico publicado en 2008

Novel anticancer agents, kayeassamins C-I from the flower of Kayea assamica of Myanmar

artículo científico publicado en 2008

Nuclear localization of SNARK; its impact on gene expression

artículo científico publicado en 2008

Oncogenic Kit signalling on the Golgi is suppressed by blocking secretory trafficking with M-COPA in gastrointestinal stromal tumours.

artículo científico publicado en 2017

Oncogenic Kit signals on endolysosomes and endoplasmic reticulum are essential for neoplastic mast cell proliferation

artículo científico publicado en 2014

Overexpression of c-Maf contributes to T-cell lymphoma in both mice and human

artículo científico publicado en 2006

Panduratins D-I, novel secondary metabolites from rhizomes of Boesenbergia pandurata

artículo científico publicado en 2008

Phase I trial of GBS-01 for advanced pancreatic cancer refractory to gemcitabine

scientific article published on 29 September 2016

Phenotypic reversion in analbuminemic rats due to an altered splicing mechanism

artículo científico publicado en 2007

Provision of a voluntary exercise environment enhances running activity and prevents obesity in Snark-deficient mice

artículo científico publicado en 2009

Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry.

artículo científico publicado en 2009

Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis.

artículo científico publicado en 2003

Regulation of caspase-6 and FLIP by the AMPK family member ARK5.

artículo científico publicado en 2004

Regulation of succinate-ubiquinone reductase and fumarate reductase activities in human complex II by phosphorylation of its flavoprotein subunit

artículo científico publicado en 2009

Report of the 16th International Symposium of the Foundation for Promotion of Cancer Research: Recent advances in pancreatic cancer

artículo científico publicado en 2003

Risk of multiple squamous cell carcinomas both in the esophagus and the head and neck region

artículo científico publicado en 2005

Role of nitric oxide (NO) in interferon-alpha therapy for hepatitis C.

artículo científico publicado en 2005

Roles of inducible nitric oxide synthase in the development and healing of experimentally induced gastric ulcers

artículo científico publicado en 2003

Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma

artículo científico publicado en 2015

Splice isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4: expression and hypoxic regulation

artículo científico publicado en 2005

Squamous cell carcinoma in situ at oropharyngeal and hypopharyngeal mucosal sites

artículo científico publicado en 2004

Study on the constituents of Mexican propolis and their cytotoxic activity against PANC-1 human pancreatic cancer cells

artículo científico publicado en 2010

Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle.

artículo científico publicado en 2010

Sucrose nonfermenting AMPK-related kinase (SNARK) regulates exercise-stimulated and ischemia-stimulated glucose transport in the heart

scientific article published on 07 September 2018

Susceptibility of Snark-deficient mice to azoxymethane-induced colorectal tumorigenesis and the formation of aberrant crypt foci

scientific article published on 27 February 2007

Susceptibility to lung cancer and genetic polymorphisms in the alcohol metabolite-related enzymes alcohol dehydrogenase 3, aldehyde dehydrogenase 2, and cytochrome P450 2E1 in the Japanese population

scientific article published on 01 July 2007

Synthesis and antitumor evaluation of arctigenin derivatives based on antiausterity strategy.

artículo científico publicado en 2012

Synthesis and evaluation of anticancer natural product analogues based on angelmarin: targeting the tolerance towards nutrient deprivation.

artículo científico publicado en 2012

Synthesis of new tricyclic thiolactams as potent antitumor agent for pancreatic cancer

artículo científico publicado en 2016

The NADH-fumarate reductase system, a novel mitochondrial energy metabolism, is a new target for anticancer therapy in tumor microenvironments

artículo científico publicado en 2010

The development and clinical use of a beam ON-LINE PET system mounted on a rotating gantry port in proton therapy

artículo científico publicado en 2010

Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis

artículo científico publicado en 2014

Thymidine Catabolism as a Metabolic Strategy for Cancer Survival.

artículo científico publicado en 2017

Thymidine catabolism promotes NADPH oxidase-derived reactive oxygen species (ROS) signalling in KB and yumoto cells.

artículo científico publicado en 2018

[Therapeutic strategies targeting cancer--specific metabolism].

artículo científico publicado en 2015

c-Maf expression in angioimmunoblastic T-cell lymphoma.

artículo científico publicado en 2007