Lista de obras -

A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.

artículo científico publicado en 2004

Analysis of Heme Iron Coordination in DGCR8: The Heme-Binding Component of the Microprocessor Complex.

artículo científico publicado en 2016

Analysis of the interactions of cytochrome b5 with flavocytochrome P450 BM3 and its domains.

artículo científico publicado en 2007

Analysis of the oxidation of short chain alkynes by flavocytochrome P450 BM3

artículo científico publicado en 2011

Applications of microbial cytochrome P450 enzymes in biotechnology and synthetic biology

artículo científico publicado en 2016

Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions

scientific journal article

Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE.

artículo científico publicado en 2017

Characterization of Cytochrome P450 Enzymes and Their Applications in Synthetic Biology

artículo científico publicado en 2018

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

scientific article published on 17 April 2020

Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5

artículo científico publicado en 2020

Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed "proximal-distal" transition probed by temperature-jump spectroscopy.

artículo científico publicado en 2007

Cytochrome P450--redox partner fusion enzymes.

artículo científico publicado en 2006

Cytochrome P450/redox partner fusion enzymes: biotechnological and toxicological prospects

scientific article published on December 2007

Cytochrome P450s: creating novel ligand sets.

artículo científico publicado en 2005

Expression, Purification, and Biochemical Characterization of the Flavocytochrome P450 CYP505A30 from Myceliophthora thermophila

artículo científico publicado en 2017

Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set.

artículo científico publicado en 2004

Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer

scientific article published on 22 September 2010

Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3

artículo científico publicado en 2010

Heme and Hemoproteins

artículo científico publicado en 2009

Heme sensor proteins

artículo científico publicado en 2013

Interaction of nitric oxide with cytochrome P450 BM3.

artículo científico publicado en 2004

Laser photoexcitation of NAD(P)H induces reduction of P450 BM3 heme domain on the microsecond time scale

artículo científico publicado en 2007

Novel haem co-ordination variants of flavocytochrome P450BM3

artículo científico publicado en 2009

Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs

scientific article published in Scientific Reports

Probing the molecular determinants of coenzyme selectivity in the P450 BM3 FAD/NADPH domain

artículo científico publicado en 2009

Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1

artículo científico publicado en 2017

Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus

artículo científico publicado en 2018

Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.

artículo científico publicado en 2006

The crystal structure of the FAD/NADPH-binding domain of flavocytochrome P450 BM3

artículo científico publicado en 2012

The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase.

artículo científico publicado en 2005

Variations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily

artículo científico publicado en 2007

What makes a P450 tick?

artículo científico publicado en 2013

Lista de obras de

A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.

Analysis of Heme Iron Coordination in DGCR8: The Heme-Binding Component of the Microprocessor Complex.

Analysis of the interactions of cytochrome b5 with flavocytochrome P450 BM3 and its domains.

Analysis of the oxidation of short chain alkynes by flavocytochrome P450 BM3

Applications of microbial cytochrome P450 enzymes in biotechnology and synthetic biology

Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions

Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE.

Characterization of Cytochrome P450 Enzymes and Their Applications in Synthetic Biology

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5

Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed "proximal-distal" transition probed by temperature-jump spectroscopy.

Cytochrome P450--redox partner fusion enzymes.

Cytochrome P450/redox partner fusion enzymes: biotechnological and toxicological prospects

Cytochrome P450s: creating novel ligand sets.

Expression, Purification, and Biochemical Characterization of the Flavocytochrome P450 CYP505A30 from Myceliophthora thermophila

Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set.

Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer

Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3

Heme and Hemoproteins

Heme sensor proteins

Interaction of nitric oxide with cytochrome P450 BM3.

Laser photoexcitation of NAD(P)H induces reduction of P450 BM3 heme domain on the microsecond time scale

Novel haem co-ordination variants of flavocytochrome P450BM3

Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs

Probing the molecular determinants of coenzyme selectivity in the P450 BM3 FAD/NADPH domain

Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1

Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus

Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.

The crystal structure of the FAD/NADPH-binding domain of flavocytochrome P450 BM3

The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase.

Variations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily

What makes a P450 tick?