Lista de obras -

A Blueprint for an International Cancer Epigenome Consortium. A Report from the AACR Cancer Epigenome Task Force ⬇️

artículo científico publicado el 27 de noviembre de 2012

A DNA hypomethylating drug alters the tumor microenvironment and improves the effectiveness of immune checkpoint inhibitors in a mouse model of pancreatic cancer

scientific article published on 14 August 2020

A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes

article

A pathologic link between Wilms tumor suppressor gene, WT1, and IFI16.

artículo científico publicado en 2008

A single nucleotide polymorphism chip-based method for combined genetic and epigenetic profiling: validation in decitabine therapy and tumor/normal comparisons

artículo científico publicado en 2006

APOE and APOC1 promoter polymorphisms and the risk of Alzheimer disease in African American and Caribbean Hispanic individuals

artículo científico publicado en 2004

Age-at-onset linkage analysis in Caribbean Hispanics with familial late-onset Alzheimer's disease

artículo científico publicado en 2007

Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs

artículo científico publicado en 2020

Allele-specific DNA methylation: beyond imprinting

artículo científico publicado en 2010

Altered DNA methylation in leukocytes with trisomy 21

artículo científico publicado en 2010

Altered PET functional brain responses in cognitively intact elderly persons at risk for Alzheimer disease (carriers of the epsilon4 allele)

artículo científico publicado en 2004

Apolipoprotein E epsilon4 and age at onset of sporadic and familial Alzheimer disease in Caribbean Hispanics

artículo científico publicado en 2006

Biallelic expression of HRAS and MUCDHL in human and mouse

artículo científico publicado en 2003

Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth.

artículo científico publicado en 2011

Breast Cancer Family History and Allele-Specific DNA Methylation in the Legacy Girls Study

artículo científico publicado en 2018

CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors

artículo científico publicado en 2004

Cancer epigenetics and targeted therapies

artículo científico publicado el 1 de marzo de 2011

Candidate gene analysis for Alzheimer's disease in adults with Down syndrome.

artículo científico publicado en 2017

Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome.

artículo científico publicado en 2015

Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21.

artículo científico publicado en 2006

Cholesterol level, statin use and Alzheimer's disease in adults with Down syndrome

artículo científico publicado en 2007

Chromosome arm 16q in Wilms tumors: unbalanced chromosomal translocations, loss of heterozygosity, and assessment of the CTCF gene

artículo científico publicado en 2002

CloudASM: an ultra-efficient cloud-based pipeline for mapping allele-specific DNA methylation

artículo científico publicado en 2020

Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation

artículo científico publicado en 2013

Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1)

artículo científico publicado en 2012

DNA Methylation Changes in Barrett’s Epithelium and Adjacent Normal Mucosa ⬇️

scholarly article

Detecting methylation quantitative trait loci using a methylation random field method

scientific article published in 2021

Distinct epigenetic profiles in children with perinatally-acquired HIV on antiretroviral therapy

artículo científico publicado en 2019

Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior

artículo científico publicado en 2016

Down syndrome and Alzheimer's disease: Common pathways, common goals

artículo científico publicado en 2014

Epidemiology of estrogen and dementia in women with Down syndrome

artículo científico publicado en 2017

Epigenetic Alterations Affecting Transcription Factors and Signaling Pathways in Stromal Cells of Endometriosis

artículo científico publicado en 2017

Epigenomic insights into common disease ⬇️

artículo científico publicado el 23 de noviembre de 2011

Erratum to: Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models.

artículo científico publicado en 2016

Estrogen receptor-Beta variants are associated with increased risk of Alzheimer's disease in women with down syndrome.

artículo científico publicado en 2011

Estrogen receptor-alpha variants increase risk of Alzheimer's disease in women with Down syndrome.

artículo científico publicado en 2008

Expanded Genomewide Scan Implicates a Novel Locus at 3q28 Among Caribbean Hispanics With Familial Alzheimer Disease

Faithful tissue-specific expression of the human chromosome 21-linked COL6A1 gene in BAC-transgenic mice.

artículo científico publicado en 2007

Familial Alzheimer disease among Caribbean Hispanics: a reexamination of its association with APOE.

artículo científico publicado en 2002

Folic acid increases global DNA methylation and reduces inflammation to prevent Helicobacter-associated gastric cancer in mice.

artículo científico publicado en 2012

Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition

artículo científico publicado en 2002

Genetic and Epigenetic Mosaicism in Cancer Precursor Tissues ⬇️

artículo científico publicado el 1 de marzo de 2003

Genetic and epigenetic pathways in Down syndrome: Insights to the brain and immune system from humans and mouse models

artículo científico publicado en 2019

Genetic epidemiology and nonsyndromic structural birth defects: from candidate genes to epigenetics

artículo científico publicado en 2014

Genetic-epigenetic interactions in cis: a major focus in the post-GWAS era

artículo científico publicado en 2017

Genome-wide divergence of DNA methylation marks in cerebral and cerebellar cortices

artículo científico publicado en 2010

Genomic profiling maps loss of heterozygosity and defines the timing and stage dependence of epigenetic and genetic events in Wilms' tumors

artículo científico publicado en 2005

Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation

artículo científico publicado en 2008

Global hypomethylation of genomic DNA in cancer-associated myofibroblasts.

artículo científico publicado en 2008

HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL ⬇️

artículo científico publicado el 19 de julio de 2011

Histone Deacetylase Inhibitors Synergistically Enhance the Cytotoxic Effect of Hypomethylating Agents in Models of Diffuse Large B-Cell Lymphoma. ⬇️

scholarly article

Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.

artículo científico publicado en 2012

Identification and expression analysis of the human mu-protocadherin gene in fetal and adult kidneys

artículo científico publicado en 2002

Immunohistochemistry for the imprinted gene product IPL/PHLDA2 for facilitating the differential diagnosis of complete hydatidiform mole.

artículo científico publicado en 2004

Inhibition of NF-κB-Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma

scientific article published on 18 March 2019

Integrative epigenomic and genomic filtering for methylation markers in hepatocellular carcinomas

artículo científico publicado en 2015

Intramuscular therapeutic vaccination targeting HPV16 induces T cell responses that localize in mucosal lesions

artículo científico publicado en 2014

Mapping allele-specific DNA methylation: a new tool for maximizing information from GWAS.

artículo científico publicado en 2010

Mapping methylation quantitative trait loci in cardiac tissues nominates risk loci and biological pathways in congenital heart disease

artículo científico publicado en 2021

Maternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes

artículo científico publicado en 2019

Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation

artículo científico publicado en 2016

Mesenchymal Stem Cells Derived Myofibroblasts Function as Niche Cells in the Normal Bone Marrow and Expand During Carcinogenesis to Promote Tumor Growth

artículo científico publicado en 2011

Methods in DNA methylation profiling

artículo científico publicado en 2009

Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy?

artículo científico publicado en 2009

Mortality is associated with apolipoprotein E epsilon4 in nondemented adults with Down syndrome.

artículo científico publicado en 2005

Mouse-based genetic modeling and analysis of Down syndrome

artículo científico publicado en 2016

NPTX2 and cognitive dysfunction in Alzheimer's Disease.

artículo científico publicado en 2017

Onset of dementia is associated with age at menopause in women with Down's syndrome

artículo científico publicado en 2003

Oral Rigosertib (ON 01910.Na) Treatment Produces An Encouraging Rate Of Transfusion Independence In Lower Risk Myelodysplastic Syndromes (MDS) Patients; A Genomic Methylation Profile Is Associated With Responses ⬇️

artículo científico publicado en 2013

PCDH10 promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis

artículo científico publicado en 2013

PEG10 is a c-MYC target gene in cancer cells

artículo científico publicado en 2006

PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression

artículo científico publicado en 2024

PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors

artículo científico publicado en 2014

Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1

artículo científico publicado en 2002

Physiological functions of imprinted genes.

artículo científico publicado en 2002

Piece of cake

artículo científico publicado en 2002

Placental growth retardation due to loss of imprinting of Phlda2

scientific article published on 01 October 2004

Placental overgrowth in mice lacking the imprinted gene Ipl

artículo científico publicado en 2002

Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer's Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome

artículo científico publicado en 2020

Polymorphisms in the promoter of the human APP gene: functional evaluation and allele frequencies in Alzheimer disease

artículo científico publicado en 2002

Polymorphisms inHSD17B1: Early Onset and Increased Risk of Alzheimer’s Disease in Women with Down Syndrome ⬇️

artículo científico publicado el 4 de marzo de 2012

Preservation of cognitive and functional ability as markers of longevity

artículo científico publicado en 2004

Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study

artículo científico publicado en 2020

Random field modeling of multi-trait multi-locus association for detecting methylation quantitative trait loci

scientific article published in 2022

Regulation of supply and demand for maternal nutrients in mammals by imprinted genes.

artículo científico publicado en 2003

Sex differences in the associations of placental epigenetic aging with fetal growth

artículo científico publicado en 2019

Stromal protein Ecm1 regulates ureteric bud patterning and branching

artículo científico publicado en 2013

Successful aging in a 70-year-old man with down syndrome: a case study

artículo científico publicado en 2008

Synergistic Combinations of Histone Deacetylase Inhibitors and Decitabine Induce a Unique Gene Expression and Epigenetic Profile In Models of Diffuse Large B-Cell Lymphoma ⬇️

artículo científico publicado en 2010

TP73 allelic expression in human brain and allele frequencies in Alzheimer's disease

artículo científico publicado en 2004

The Effect of Folate Supplementation on Global Methylation and Progression of Gastric Cancer in the Transgenic Hypergastrinemic Murine Model

artículo científico publicado en 2011

The Saitohin 'Q7R' polymorphism and tau haplotype in multi-ethnic Alzheimer disease and Parkinson's disease cohorts

artículo científico publicado en 2003

The Tnfrh1 (Tnfrsf23) gene is weakly imprinted in several organs and expressed at the trophoblast-decidua interface

artículo científico publicado en 2002

The Wnt/beta-catenin pathway in Wilms tumors and prostate cancers

artículo científico publicado en 2007

The caBIG® Life Science Business Architecture Model ⬇️

artículo científico publicado el 29 de marzo de 2011

The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain.

artículo científico publicado en 2017

Thirtyfold multiplex genotyping of the p53 gene using solid phase capturable dideoxynucleotides and mass spectrometry

artículo científico publicado en 2004

Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models

artículo científico publicado en 2015

Trans-acting epigenetic effects of chromosomal aneuploidies: lessons from Down syndrome and mouse models

artículo científico publicado en 2016

Two somatic biallelic lesions within and near SMAD4 in a human breast cancer cell line

artículo científico

Variants in CYP17 and CYP19 Cytochrome P450 Genes are Associated with Onset of Alzheimer's Disease in Women with Down Syndrome ⬇️

artículo científico publicado el 1 de enero de 2012

Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2

artículo científico publicado en 2006

Lista de obras de

A Blueprint for an International Cancer Epigenome Consortium. A Report from the AACR Cancer Epigenome Task Force ⬇️

A DNA hypomethylating drug alters the tumor microenvironment and improves the effectiveness of immune checkpoint inhibitors in a mouse model of pancreatic cancer

A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes

A pathologic link between Wilms tumor suppressor gene, WT1, and IFI16.

A single nucleotide polymorphism chip-based method for combined genetic and epigenetic profiling: validation in decitabine therapy and tumor/normal comparisons

APOE and APOC1 promoter polymorphisms and the risk of Alzheimer disease in African American and Caribbean Hispanic individuals

Age-at-onset linkage analysis in Caribbean Hispanics with familial late-onset Alzheimer's disease

Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs

Allele-specific DNA methylation: beyond imprinting

Altered DNA methylation in leukocytes with trisomy 21

Altered PET functional brain responses in cognitively intact elderly persons at risk for Alzheimer disease (carriers of the epsilon4 allele)

Apolipoprotein E epsilon4 and age at onset of sporadic and familial Alzheimer disease in Caribbean Hispanics

Biallelic expression of HRAS and MUCDHL in human and mouse

Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth.

Breast Cancer Family History and Allele-Specific DNA Methylation in the Legacy Girls Study

CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors

Cancer epigenetics and targeted therapies

Candidate gene analysis for Alzheimer's disease in adults with Down syndrome.

Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome.

Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21.

Cholesterol level, statin use and Alzheimer's disease in adults with Down syndrome

Chromosome arm 16q in Wilms tumors: unbalanced chromosomal translocations, loss of heterozygosity, and assessment of the CTCF gene

CloudASM: an ultra-efficient cloud-based pipeline for mapping allele-specific DNA methylation

Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation

Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1)

DNA Methylation Changes in Barrett’s Epithelium and Adjacent Normal Mucosa ⬇️

Detecting methylation quantitative trait loci using a methylation random field method

Distinct epigenetic profiles in children with perinatally-acquired HIV on antiretroviral therapy

Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior

Down syndrome and Alzheimer's disease: Common pathways, common goals

Epidemiology of estrogen and dementia in women with Down syndrome

Epigenetic Alterations Affecting Transcription Factors and Signaling Pathways in Stromal Cells of Endometriosis

Epigenomic insights into common disease ⬇️

Erratum to: Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models.

Estrogen receptor-Beta variants are associated with increased risk of Alzheimer's disease in women with down syndrome.

Estrogen receptor-alpha variants increase risk of Alzheimer's disease in women with Down syndrome.

Expanded Genomewide Scan Implicates a Novel Locus at 3q28 Among Caribbean Hispanics With Familial Alzheimer Disease

Faithful tissue-specific expression of the human chromosome 21-linked COL6A1 gene in BAC-transgenic mice.

Familial Alzheimer disease among Caribbean Hispanics: a reexamination of its association with APOE.

Folic acid increases global DNA methylation and reduces inflammation to prevent Helicobacter-associated gastric cancer in mice.

Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition

Genetic and Epigenetic Mosaicism in Cancer Precursor Tissues ⬇️

Genetic and epigenetic pathways in Down syndrome: Insights to the brain and immune system from humans and mouse models

Genetic epidemiology and nonsyndromic structural birth defects: from candidate genes to epigenetics

Genetic-epigenetic interactions in cis: a major focus in the post-GWAS era

Genome-wide divergence of DNA methylation marks in cerebral and cerebellar cortices

Genomic profiling maps loss of heterozygosity and defines the timing and stage dependence of epigenetic and genetic events in Wilms' tumors

Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation

Global hypomethylation of genomic DNA in cancer-associated myofibroblasts.

HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL ⬇️

Histone Deacetylase Inhibitors Synergistically Enhance the Cytotoxic Effect of Hypomethylating Agents in Models of Diffuse Large B-Cell Lymphoma. ⬇️

Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.

Identification and expression analysis of the human mu-protocadherin gene in fetal and adult kidneys

Immunohistochemistry for the imprinted gene product IPL/PHLDA2 for facilitating the differential diagnosis of complete hydatidiform mole.

Inhibition of NF-κB-Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma

Integrative epigenomic and genomic filtering for methylation markers in hepatocellular carcinomas

Intramuscular therapeutic vaccination targeting HPV16 induces T cell responses that localize in mucosal lesions

Mapping allele-specific DNA methylation: a new tool for maximizing information from GWAS.

Mapping methylation quantitative trait loci in cardiac tissues nominates risk loci and biological pathways in congenital heart disease

Maternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes

Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation

Mesenchymal Stem Cells Derived Myofibroblasts Function as Niche Cells in the Normal Bone Marrow and Expand During Carcinogenesis to Promote Tumor Growth

Methods in DNA methylation profiling

Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy?

Mortality is associated with apolipoprotein E epsilon4 in nondemented adults with Down syndrome.

Mouse-based genetic modeling and analysis of Down syndrome

NPTX2 and cognitive dysfunction in Alzheimer's Disease.

Onset of dementia is associated with age at menopause in women with Down's syndrome

Oral Rigosertib (ON 01910.Na) Treatment Produces An Encouraging Rate Of Transfusion Independence In Lower Risk Myelodysplastic Syndromes (MDS) Patients; A Genomic Methylation Profile Is Associated With Responses ⬇️

PCDH10 promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis

PEG10 is a c-MYC target gene in cancer cells

PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression

PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors

Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1

Physiological functions of imprinted genes.

Piece of cake

Placental growth retardation due to loss of imprinting of Phlda2

Placental overgrowth in mice lacking the imprinted gene Ipl

Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer's Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome