Lista de obras -

A generic approach for simultaneous measurements of total antibody and cleavable antibody-conjugated drug by LC/MS/MS.

artículo científico publicado en 2017

A monomethyl auristatin E-conjugated antibody to guanylyl cyclase C is cytotoxic to target-expressing cells in vitro and in vivo

artículo científico publicado en 2018

A novel role for CCL3 (MIP-1α) in myeloma-induced bone disease via osteocalcin downregulation and inhibition of osteoblast function

artículo científico publicado en 2011

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.

artículo científico publicado en 2018

Ability of flt3 ligand to stimulate the in vitro growth of primitive murine hematopoietic progenitors is potently and directly inhibited by transforming growth factor-beta and tumor necrosis factor-alpha

scientific article published on 01 June 1996

Antibody-drug conjugate directed against the guanylyl cyclase antigen for the treatment of gastrointestinal malignancies

artículo científico publicado en 2016

Bidirectional effect of interleukin-10 on early murine B-cell development: stimulation of flt3-ligand plus interleukin-7-dependent generation of CD19(-) ProB cells from uncommitted bone marrow progenitor cells and growth inhibition of CD19(+) ProB c

artículo científico publicado en 1997

Chemoresistance: impact of nuclear factor (NF)-kappaB inhibition by small interfering RNA. Commentary re J. Guo et al., Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the NF-kappaB p65 subunit. Clin Cancer Re

artículo científico publicado en 2004

Combined signaling through interleukin-7 receptors and flt3 but not c-kit potently and selectively promotes B-cell commitment and differentiation from uncommitted murine bone marrow progenitor cells.

artículo científico publicado en 1996

Cytotoxic lymphocyte maturation factor (interleukin 12) is a synergistic growth factor for hematopoietic stem cells

artículo científico publicado en 1993

Design and Optimization of Potent and Orally Bioavailable Tetrahydronaphthalene Raf Inhibitors ⬇️

artículo científico publicado el 22 de febrero de 2011

Direct synergistic effects of IL-4 and IL-11 on proliferation of primitive hematopoietic progenitor cells

artículo científico publicado en 1995

Distinct and direct synergistic effects of IL-1 and IL-6 on proliferation and differentiation of primitive murine hematopoietic progenitor cells in vitro

artículo científico publicado en 1994

Evidence for engraftment of donor-type multipotent CD34+ cells in a patient with selective T-lymphocyte reconstitution after bone marrow transplantation for B-SCID ⬇️

artículo científico publicado el 15 de noviembre de 1994

Functional differences between CD38- and DR- subfractions of CD34+ bone marrow cells

scientific article published on 01 September 1994

Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis

artículo científico publicado en 2007

Haemopoietic progenitor cell differentiation: flow cytometric assessment in bone marrow and thymus

artículo científico publicado en 1995

IL-7 stimulates CSF-induced proliferation of murine bone marrow macrophages and Mac-1+ myeloid progenitors in vitro

scientific article published on 01 July 1994

Inhibition of NEDD8-Activating Enzyme Induces Rereplication and Apoptosis in Human Tumor Cells Consistent with Deregulating CDT1 Turnover ⬇️

artículo científico publicado el 12 de abril de 2011

Inhibition of stem cell factor-induced proliferation of primitive murine hematopoietic progenitor cells signaled through the 75-kilodalton tumor necrosis factor receptor. Regulation of c-kit and p53 expression

artículo científico publicado en 1995

Interleukin 13: novel role in direct regulation of proliferation and differentiation of primitive hematopoietic progenitor cells

artículo científico publicado en 1994

Lineage commitment of CD34+ human hematopoietic progenitor cells.

artículo científico publicado en 1996

Novel role of interleukin 7 in myelopoiesis: stimulation of primitive murine hematopoietic progenitor cells ⬇️

artículo científico publicado el 1 de noviembre de 1993

Phase I assessment of new mechanism-based pharmacodynamic biomarkers for MLN8054, a small-molecule inhibitor of Aurora A kinase

artículo científico publicado en 2010

Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody-Drug Conjugate in Patient-Derived Xenografts

artículo científico publicado en 2020

Role of the 75-kDa tumor necrosis factor receptor: inhibition of early hematopoiesis ⬇️

artículo científico publicado el 25 de octubre de 1994

Stem cell factor and interleukin-7 synergize to enhance early myelopoiesis in vitro

artículo científico publicado en 1994

T lymphocyte differentiation in vitro from adult human prethymic CD34+ bone marrow cells ⬇️

artículo científico publicado el 1 de junio de 1993

TNF-alpha bidirectionally modulates the viability of primitive murine hematopoietic progenitor cells in vitro

scientific article published on 01 August 1996

The FLT3 ligand is a direct and potent stimulator of the growth of primitive and committed human CD34+ bone marrow progenitor cells in vitro

scientific article published on 01 February 1996

The FLT3 ligand potently and directly stimulates the growth and expansion of primitive murine bone marrow progenitor cells in vitro: synergistic interactions with interleukin (IL) 11, IL-12, and other hematopoietic growth factors

artículo científico publicado en 1995

The flt3 ligand promotes the survival of primitive hemopoietic progenitor cells with myeloid as well as B lymphoid potential. Suppression of apoptosis and counteraction by TNF-alpha and TGF-beta.

artículo científico publicado en 1996

Thrombopoietin promotes adhesion of primitive human hemopoietic cells to fibronectin and vascular cell adhesion molecule-1: role of activation of very late antigen (VLA)-4 and VLA-5.

artículo científico publicado en 1997

Thrombopoietin, a direct stimulator of viability and multilineage growth of primitive bone marrow progenitor cells

artículo científico publicado en 1996

Thrombopoietin, but not erythropoietin promotes viability and inhibits apoptosis of multipotent murine hematopoietic progenitor cells in vitro

scientific article published on 01 October 1996

Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: distinct interactions with the ligands for c-kit and FLT3

Thymic stromal cells support differentiation of natural killer cells from CD34+ bone marrow cells in vitro.

artículo científico publicado en 1995

Transforming growth factor-beta1 abrogates Fas-induced growth suppression and apoptosis of murine bone marrow progenitor cells

artículo científico publicado en 1997

Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors

artículo científico publicado en 2011

Tumor necrosis factor-alpha (TNF-alpha) potently enhances in vitro macrophage production from primitive murine hematopoietic progenitor cells in combination with stem cell factor and interleukin-7: novel stimulatory role of p55 TNF receptors ⬇️

artículo científico publicado el 1 de septiembre de 1994

Lista de obras de

A generic approach for simultaneous measurements of total antibody and cleavable antibody-conjugated drug by LC/MS/MS.

A monomethyl auristatin E-conjugated antibody to guanylyl cyclase C is cytotoxic to target-expressing cells in vitro and in vivo

A novel role for CCL3 (MIP-1α) in myeloma-induced bone disease via osteocalcin downregulation and inhibition of osteoblast function

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.

Ability of flt3 ligand to stimulate the in vitro growth of primitive murine hematopoietic progenitors is potently and directly inhibited by transforming growth factor-beta and tumor necrosis factor-alpha

Antibody-drug conjugate directed against the guanylyl cyclase antigen for the treatment of gastrointestinal malignancies

Bidirectional effect of interleukin-10 on early murine B-cell development: stimulation of flt3-ligand plus interleukin-7-dependent generation of CD19(-) ProB cells from uncommitted bone marrow progenitor cells and growth inhibition of CD19(+) ProB c

Chemoresistance: impact of nuclear factor (NF)-kappaB inhibition by small interfering RNA. Commentary re J. Guo et al., Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the NF-kappaB p65 subunit. Clin Cancer Re

Combined signaling through interleukin-7 receptors and flt3 but not c-kit potently and selectively promotes B-cell commitment and differentiation from uncommitted murine bone marrow progenitor cells.

Cytotoxic lymphocyte maturation factor (interleukin 12) is a synergistic growth factor for hematopoietic stem cells

Design and Optimization of Potent and Orally Bioavailable Tetrahydronaphthalene Raf Inhibitors ⬇️

Direct synergistic effects of IL-4 and IL-11 on proliferation of primitive hematopoietic progenitor cells

Distinct and direct synergistic effects of IL-1 and IL-6 on proliferation and differentiation of primitive murine hematopoietic progenitor cells in vitro

Evidence for engraftment of donor-type multipotent CD34+ cells in a patient with selective T-lymphocyte reconstitution after bone marrow transplantation for B-SCID ⬇️

Functional differences between CD38- and DR- subfractions of CD34+ bone marrow cells

Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis

Haemopoietic progenitor cell differentiation: flow cytometric assessment in bone marrow and thymus

IL-7 stimulates CSF-induced proliferation of murine bone marrow macrophages and Mac-1+ myeloid progenitors in vitro

Inhibition of NEDD8-Activating Enzyme Induces Rereplication and Apoptosis in Human Tumor Cells Consistent with Deregulating CDT1 Turnover ⬇️

Inhibition of stem cell factor-induced proliferation of primitive murine hematopoietic progenitor cells signaled through the 75-kilodalton tumor necrosis factor receptor. Regulation of c-kit and p53 expression

Interleukin 13: novel role in direct regulation of proliferation and differentiation of primitive hematopoietic progenitor cells

Lineage commitment of CD34+ human hematopoietic progenitor cells.

Novel role of interleukin 7 in myelopoiesis: stimulation of primitive murine hematopoietic progenitor cells ⬇️

Phase I assessment of new mechanism-based pharmacodynamic biomarkers for MLN8054, a small-molecule inhibitor of Aurora A kinase

Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody-Drug Conjugate in Patient-Derived Xenografts

Role of the 75-kDa tumor necrosis factor receptor: inhibition of early hematopoiesis ⬇️

Stem cell factor and interleukin-7 synergize to enhance early myelopoiesis in vitro

T lymphocyte differentiation in vitro from adult human prethymic CD34+ bone marrow cells ⬇️

TNF-alpha bidirectionally modulates the viability of primitive murine hematopoietic progenitor cells in vitro

The FLT3 ligand is a direct and potent stimulator of the growth of primitive and committed human CD34+ bone marrow progenitor cells in vitro

The FLT3 ligand potently and directly stimulates the growth and expansion of primitive murine bone marrow progenitor cells in vitro: synergistic interactions with interleukin (IL) 11, IL-12, and other hematopoietic growth factors

The flt3 ligand promotes the survival of primitive hemopoietic progenitor cells with myeloid as well as B lymphoid potential. Suppression of apoptosis and counteraction by TNF-alpha and TGF-beta.

Thrombopoietin promotes adhesion of primitive human hemopoietic cells to fibronectin and vascular cell adhesion molecule-1: role of activation of very late antigen (VLA)-4 and VLA-5.

Thrombopoietin, a direct stimulator of viability and multilineage growth of primitive bone marrow progenitor cells

Thrombopoietin, but not erythropoietin promotes viability and inhibits apoptosis of multipotent murine hematopoietic progenitor cells in vitro

Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: distinct interactions with the ligands for c-kit and FLT3

Thymic stromal cells support differentiation of natural killer cells from CD34+ bone marrow cells in vitro.

Transforming growth factor-beta1 abrogates Fas-induced growth suppression and apoptosis of murine bone marrow progenitor cells

Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors

Tumor necrosis factor-alpha (TNF-alpha) potently enhances in vitro macrophage production from primitive murine hematopoietic progenitor cells in combination with stem cell factor and interleukin-7: novel stimulatory role of p55 TNF receptors ⬇️