Lista de obras -

A comparison of thermal enhancement of cis-diamminedichloroplatinum (II) induced renal and intestinal toxicities by whole body hyperthermia in the rat

artículo científico publicado en 1989

A texaphyrin-oxaliplatin conjugate that overcomes both pharmacologic and molecular mechanisms of cisplatin resistance in cancer cells.

artículo científico publicado en 2012

ATP11B mediates platinum resistance in ovarian cancer

artículo científico publicado en 2013

ATP11B mediates platinum resistance in ovarian cancer.

artículo científico publicado en 2013

ATP11B mediates platinum resistance in ovarian cancer.

artículo científico publicado en 2018

Activation of Platinum(IV) Prodrugs By Motexafin Gadolinium as a Redox Mediator.

artículo científico publicado en 2016

Alterations in hepatic and renal levels of glutathione and activities of glutathione S-transferase from rats treated with cis-dichlorodiammineplatinum-II

artículo científico publicado en 1982

Ammine/amine platinum (II) complexes effective in vivo against murine tumors sensitive or resistant to cisplatin and tetraplatin

scientific article published on 01 January 1994

Antitumor activity of isomeric 1,2-diaminocyclohexane platinum(IV) complexes

artículo científico publicado en 1994

Axial ligands and alicyclic ring size modulate the activity and biochemical pharmacology of ammine/cycloalkylamine-platinum(IV) complexes in tumor cells resistant to cis-diamminedichloroplatinum(II) or trans-1R,2R-1S,2S-diaminocyclohexanetetrachloro

artículo científico publicado en 1994

Bimodal effects of 1R,2R-diaminocyclohexane(trans-diacetato)(dichloro)platinum(IV) on cell cycle checkpoints.

artículo científico publicado en 2001

Biochemical pharmacology of homologous alicyclic mixed amine platinum(II) complexes in sensitive and resistant tumor cell lines

artículo científico publicado en 1994

Biologic effects of dopamine on tumor vasculature in ovarian carcinoma

artículo científico publicado en 2013

Bismuth- and lead-texaphyrin complexes: towards potential α-core emitters for radiotherapy.

artículo científico publicado en 2010

Bleomycin-metal interaction: Ferrous iron-initiated chemiluminescence ⬇️

artículo científico publicado el 29 de abril de 1983

Cellular pharmacology of liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (II) in mouse resident peritoneal macrophages, Kupffer cells, and hepatocytes

artículo científico publicado en 1988

Chemical and biological studies on a series of novel (trans-(1R,2R)-, trans-(1S,2S)-, and cis-1,2-diaminocyclohexane)platinum(IV) carboxylate complexes

scientific article published on 01 January 1997

Chronic effect of whole-body hyperthermia combined simultaneously with cis-diamminedichloroplatinum (II) on normal tissue in rat

artículo científico publicado en 1995

Circumvention of platinum resistance: structure-activity relationship for homologous series of ammine/amine platinum(II) complexes in L1210 cell lines

artículo científico publicado en 1994

Cisplatin in Combination with MDM2 Inhibition Downregulates Rad51 Recombinase in a Bimodal Manner to Inhibit Homologous Recombination and Augment Tumor Cell Kill

artículo científico publicado en 2020

Collagen matrix cisplatin prevents local tumor growth after margin-positive resection

artículo científico publicado en 1995

Copper transporter CTR1 expression and tissue platinum concentration in non-small cell lung cancer

artículo científico publicado en 2014

Correlation of total and interstrand DNA adducts in tumor and kidney with antitumor efficacies and differential nephrotoxicities of cis-ammine/cyclohexylamine-dichloroplatinum(II) and cisplatin.

artículo científico publicado en 1994

Cytotoxicity and tolerance to DNA adducts of alicyclic mixed amine platinum(II) homologs in tumor models sensitive and resistant to cisplatin or tetraplatin.

artículo científico publicado en 1998

Differential antitumor activity and toxicity of isomeric 1,2-diaminocyclohexane platinum (II) complexes

artículo científico publicado en 1993

Differential cytotoxicity, uptake and DNA binding of tetraplatin and analogous isomers in sensitive and resistant cancer cell lines.

artículo científico publicado en 1993

Drug-dependent functionalization of wild-type and mutant p53 in cisplatin-resistant human ovarian tumor cells

artículo científico publicado en 2016

EGF receptor and p21WAF1 expression are reciprocally altered as ME-180 cervical carcinoma cells progress from high to low cisplatin sensitivity

scientific article published on 01 January 2000

Effect of a specific 5HT uptake inhibitor (citalopram) on drug accumulation by rat lung slices

artículo científico publicado en 1980

Effect of adriamycin combined with whole body hyperthermia on tumor and normal tissues

artículo científico publicado en 1991

Effect of carboplatin combined with whole body hyperthermia on normal tissue and tumor in rats

artículo científico publicado en 1991

Effect of whole body hyperthermia on cis-diamminedichloroplatinum (II)-induced antitumour activity and tissue Pt-distribution: do anaesthetics influence the therapeutic ratio?

artículo científico publicado en 1993

Enhanced sensitivity of human colon tumor cell lines in vitro in response to thermochemoimmunotherapy ⬇️

artículo científico publicado el 1 de octubre de 1992

Expression of p53 in cisplatin-resistant ovarian cancer cell lines: modulation with the novel platinum analogue (1R, 2R-diaminocyclohexane)(trans-diacetato)(dichloro)-platinum(IV)

scientific article published on 01 March 1999

Extracorporeal hemofiltration: a model for decreasing systemic drug exposure with intra-arterial chemotherapy

artículo científico publicado en 1990

Fever-range whole body thermotherapy combined with oxaliplatin: a curative regimen in a pre-clinical breast cancer model

artículo científico publicado en 2010

Gadolinium texaphyrin (Gd-Tex)-malonato-platinum conjugates: synthesis and comparison with carboplatin in normal and Pt-resistant cell lines

artículo científico publicado en 2009

Glutathione-mediated modulation of tetraplatin activity against sensitive and resistant tumor cells.

artículo científico publicado en 1994

Haematological toxicity of carboplatin and cisplatin combined with whole body hyperthermia in rats

artículo científico publicado en 1993

Hepatic cytochrome P-450-dependent metabolism and enzymatic conjugation of foreign compounds in vitamin A-deficient rats

scientific article published on 01 January 1980

In vitro and in vivo murine metabolism of spirogermanium ⬇️

artículo científico publicado el 1 de enero de 1991

Increased doxorubicin levels in hepatic tumors with reduced systemic drug exposure achieved with complete hepatic venous isolation and extracorporeal chemofiltration

artículo científico publicado en 1993

Increased sensitivity of a metastatic model of prostate cancer to a novel tetravalent platinum analog.

artículo científico publicado en 2005

Increased therapeutic efficacy induced by tumor necrosis factor alpha combined with platinum complexes and whole-body hyperthermia in rats ⬇️

artículo científico publicado el 1 de agosto de 1992

Increased therapeutic gain of combined cis-diamminedichloroplatinum (II) and whole body hyperthermia therapy by optimal heat/drug scheduling

scientific article published on 01 December 1989

Independent pathways of p53 induction by cisplatin and X-rays in a cisplatin-resistant ovarian tumor cell line ⬇️

artículo científico publicado el 15 de febrero de 1998

Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities

artículo científico publicado en 2005

Kinetics of tissue disposition of cis-ammine/cyclohexylamine-dichloroplatinum(II) and cisplatin in mice bearing FSaIIC tumors

scientific article published on 01 January 1994

Lack of correlation between cortisol-induced precocious maturation of the fetal rabbit lung and drug metabolism ⬇️

artículo científico publicado el 1 de marzo de 1979

Metabolism and biliary excretion of sulfobromophthalein in vitamin A deficiency

scientific article published on 01 October 1980

Model platinum nucleobase and nucleoside complexes and antitumor activity: X-ray crystal structure of [PtIV(trans-1R,2R-diaminocyclohexane)trans-(acetate)2(9-ethylguanine)Cl]NO3.H2O.

artículo científico publicado en 2005

Modulation of cytotoxicity and cellular pharmacology of 1,2-diaminocyclohexane platinum (IV) complexes mediated by axial and equatorial ligands

artículo científico publicado en 1993

Modulatory effect of axial and equatorial ligands on antitumor activities of trans-1R,2R-diaminocyclohexane platinum(IV) complexes

scientific article published on 01 April 1994

Oncolytic HSV therapy modulates vesicular trafficking inducing cisplatin sensitivity and anti-tumor immunity

scientific article published on 21 October 2020

Organ distribution and tumor uptake of liposome entrapped cis-bis-neodecanoato trans-R, R-1,2 diaminocyclohexane platinum (II) administered intravenously and into the proper hepatic artery

artículo científico publicado en 1988

Overcoming biochemical pharmacologic mechanisms of platinum resistance with a texaphyrin–platinum conjugate ⬇️

artículo científico publicado el 26 de enero de 2011

Overexpression of edg-2/vzg-1 induces apoptosis and anoikis in ovarian cancer cells in a lysophosphatidic acid-independent manner

artículo científico publicado en 1999

Oxaliplatin Pt(IV) prodrugs conjugated to gadolinium-texaphyrin as potential antitumor agents

artículo científico publicado en 2020

PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis

artículo científico publicado en 2019

Pharmacokinetics of intravenously injected [3H]tetrachloro(D,L-trans)1,2-diaminocyclohexane platinum (IV) (tetraplatin) in mice ⬇️

artículo científico publicado el 1 de septiembre de 1992

Pharmacokinetics of liposome-entrapped cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II) and cisplatin given i.v. and i.p. in the rat

artículo científico publicado el 1 de enero de 1992

Pharmacokinetics of tetraplatin administered intraperitoneally with reduced glutathione in mice.

artículo científico publicado en 1994

Phase I clinical and pharmacological study of intraperitoneal cis-bis-neodecanoato( trans- R, R-1, 2-diaminocyclohexane)-platinum II entrapped in multilamellar liposome vesicles

artículo científico publicado en 2003

Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions

artículo científico publicado en 1997

Phase I study of azacitidine and oxaliplatin in patients with advanced cancers that have relapsed or are refractory to any platinum therapy

artículo científico publicado en 2015

Photoinduced reduction of Pt(IV) within an anti-proliferative Pt(IV)-texaphyrin conjugate

artículo científico publicado en 2014

Physiologic and pathologic drug resistance in ovarian carcinoma--a hypothesis based on a clonal progression model

artículo científico publicado en 1998

Platinum(IV)-Ferrocene Conjugates and Their Cyclodextrin Host-Guest Complexes

artículo científico publicado en 2019

Preparation, characterization, and antitumor activity of new cisplatin analogs with homopiperazines: crystal structure of [PtII(1-methylhomopiperazine)(methylmalonato)].2H2O.

artículo científico publicado en 1999

Preparation, characterization, and antitumor activity of new cisplatin analogues with 1-methyl-4-(methylamino)piperidine: crystal structure of [PtII(1-methyl-4-(methylamino) piperidine)(oxalate)].

artículo científico publicado en 2003

Preparation, characterization, and antitumor activity of new ethylenediamine platinum(IV) complexes containing mixed carboxylate ligands

artículo científico publicado en 1993

Preparation, characterization, and antitumor activity of water-soluble aminoalkanol platinum(II) complexes

artículo científico publicado en 1991

Protective effect of ICRF-187 against normal tissue injury induced by adriamycin in combination with whole body hyperthermia

artículo científico publicado en 1991

Protein expression profiling identifies differential modulation of homologous recombination by platinum-based antitumor agents

artículo científico publicado en 2020

Protein kinase inhibitors emodin and dichloro-ribofuranosylbenzimidazole modulate the cellular accumulation and cytotoxicity of cisplatin in a schedule-dependent manner

artículo científico publicado en 2009

Pulmonary accumulation of drugs in vitamin A deficiency

scientific article published on 01 January 1980

Recent developments in texaphyrin chemistry and drug discovery

scientific article published on 04 April 2013

Recruitment of trimeric proliferating cell nuclear antigen by G1-phase cyclin-dependent kinases following DNA damage with platinum-based antitumour agents

artículo científico publicado en 2013

Relative pulmonary toxicity and antitumor effects of two new bleomycin analogs, pepleomycin and tallysomycin A

artículo científico publicado el 1 de abril de 1980

Role of p53 in the ability of 1,2-diaminocyclohexane-diacetato-dichloro-Pt(IV) to circumvent cisplatin resistance

artículo científico publicado en 1999

Sex-dependent differences in the effects of portacaval anastomosis on hepatic monooxygenases in rats

scientific article published on 01 February 1982

Species and dose differences in the accumulation of imipramine by mammalian lungs ⬇️

artículo científico publicado el 1 de julio de 1981

Status of p53 phosphorylation and function in sensitive and resistant human cancer models exposed to platinum-based DNA damaging agents.

artículo científico publicado en 2003

Stimulation of microsomal drug oxidation in liver and kidney of rats treated with the oncolytic agent cis-dichlorodiammineplatinum-II

artículo científico publicado en 1983

Synthesis and antitumor activity of 1,2-diaminocyclohexane platinum(IV) complexes.

artículo científico publicado en 1994

Synthesis and antitumor activity of ammine/amine platinum(II) and (IV) complexes

artículo científico publicado en 1993

Synthesis, characterization and cytotoxicity of new platinum(IV) axial carboxylate complexes: crystal structure of potential antitumor agent [PtIV(trans-1R,2R-diaminocyclohexane)trans(acetate)2Cl2].

artículo científico publicado en 2000

Synthesis, characterization, and antitumor activity of 1,2-bis(diphenylphosphino) ethane platinum(II) and palladium(II) complexes

artículo científico publicado en 1990

Synthesis, characterization, and antitumor activity of a series of novel cisplatin analogs with cis-1,4-diaminocyclohexane as nonleaving amine group

artículo científico publicado en 1996

Synthesis, characterization, and antitumor activity of amine platinum(II) and (IV) tellurate complexes

artículo científico publicado en 1994

Synthesis, characterization, and antitumor activity of new chloroethylamine platinum complexes ⬇️

artículo científico publicado el 15 de febrero de 1992

Synthesis, characterization, and antitumor activity of new platinum(IV) trans-carboxylate complexes: crystal structure of [Pt(cis-1,4-DACH)trans-(acetate)2Cl2]

artículo científico publicado en 1998

Tetravalent platinum complexes with ammine/amine carrier ligand configuration: circumvention of platinum resistance in vivo.

artículo científico publicado en 1994

The effect of chlorpromazine on the uptake and efflux of paraquat in rat lung slices ⬇️

artículo científico publicado el 30 de septiembre de 1979

The effect of unilateral pneumonectomy on in vitro drug metabolism by the contralateral lung of rabbits ⬇️

artículo científico publicado el 1 de julio de 1979

The effect of vitamin A deficiency on hepatic, renal and pulmonary glutathione S-transferase activities in the rat.

artículo científico publicado en 1980

The effects of anaesthetics on cisplatinum-induced toxicity at normal temperatures and during whole-body hyperthermia: the influence of NaCl concentration of the vehicle

artículo científico publicado en 1988

The effects of α-tocopherol on the toxicity, disposition, and metabolism of adriamycin in mice ⬇️

artículo científico publicado el 15 de junio de 1979

The impact of S- and G2-checkpoint response on the fidelity of G1-arrest by cisplatin and its comparison to a non-cross-resistant platinum(IV) analog ⬇️

artículo científico publicado el 18 de mayo de 2011

The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells

artículo científico publicado en 2011

Therapeutic Targeting of ATP7B in Ovarian Carcinoma.

artículo científico publicado en 2009

Thermal enhancement of drug uptake and DNA adducts as a possible mechanism for the effect of sequencing hyperthermia on cisplatin-induced cytotoxicity in L1210 cells

scientific article published on 01 January 1994

Tissue platinum concentration and tumor response in non-small-cell lung cancer

artículo científico publicado en 2012

Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21

artículo científico publicado en 2006

Uptake and efflux of 14C-paraquat by rat lung slices: The effect of imipramine and other drugs ⬇️

artículo científico publicado el 1 de julio de 1979

o-(beta-Hydroxyethyl)-rutoside-mediated protection of renal injury associated with cis-diamminedichloroplatinum(II)/hyperthermia treatment

scientific article published on 01 April 1988

Lista de obras de

A comparison of thermal enhancement of cis-diamminedichloroplatinum (II) induced renal and intestinal toxicities by whole body hyperthermia in the rat

A texaphyrin-oxaliplatin conjugate that overcomes both pharmacologic and molecular mechanisms of cisplatin resistance in cancer cells.

ATP11B mediates platinum resistance in ovarian cancer

ATP11B mediates platinum resistance in ovarian cancer.

ATP11B mediates platinum resistance in ovarian cancer.

Activation of Platinum(IV) Prodrugs By Motexafin Gadolinium as a Redox Mediator.

Alterations in hepatic and renal levels of glutathione and activities of glutathione S-transferase from rats treated with cis-dichlorodiammineplatinum-II

Ammine/amine platinum (II) complexes effective in vivo against murine tumors sensitive or resistant to cisplatin and tetraplatin

Antitumor activity of isomeric 1,2-diaminocyclohexane platinum(IV) complexes

Axial ligands and alicyclic ring size modulate the activity and biochemical pharmacology of ammine/cycloalkylamine-platinum(IV) complexes in tumor cells resistant to cis-diamminedichloroplatinum(II) or trans-1R,2R-1S,2S-diaminocyclohexanetetrachloro

Bimodal effects of 1R,2R-diaminocyclohexane(trans-diacetato)(dichloro)platinum(IV) on cell cycle checkpoints.

Biochemical pharmacology of homologous alicyclic mixed amine platinum(II) complexes in sensitive and resistant tumor cell lines

Biologic effects of dopamine on tumor vasculature in ovarian carcinoma

Bismuth- and lead-texaphyrin complexes: towards potential α-core emitters for radiotherapy.

Bleomycin-metal interaction: Ferrous iron-initiated chemiluminescence ⬇️

Cellular pharmacology of liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (II) in mouse resident peritoneal macrophages, Kupffer cells, and hepatocytes

Chemical and biological studies on a series of novel (trans-(1R,2R)-, trans-(1S,2S)-, and cis-1,2-diaminocyclohexane)platinum(IV) carboxylate complexes

Chronic effect of whole-body hyperthermia combined simultaneously with cis-diamminedichloroplatinum (II) on normal tissue in rat

Circumvention of platinum resistance: structure-activity relationship for homologous series of ammine/amine platinum(II) complexes in L1210 cell lines

Cisplatin in Combination with MDM2 Inhibition Downregulates Rad51 Recombinase in a Bimodal Manner to Inhibit Homologous Recombination and Augment Tumor Cell Kill

Collagen matrix cisplatin prevents local tumor growth after margin-positive resection

Copper transporter CTR1 expression and tissue platinum concentration in non-small cell lung cancer

Correlation of total and interstrand DNA adducts in tumor and kidney with antitumor efficacies and differential nephrotoxicities of cis-ammine/cyclohexylamine-dichloroplatinum(II) and cisplatin.

Cytotoxicity and tolerance to DNA adducts of alicyclic mixed amine platinum(II) homologs in tumor models sensitive and resistant to cisplatin or tetraplatin.

Differential antitumor activity and toxicity of isomeric 1,2-diaminocyclohexane platinum (II) complexes

Differential cytotoxicity, uptake and DNA binding of tetraplatin and analogous isomers in sensitive and resistant cancer cell lines.

Drug-dependent functionalization of wild-type and mutant p53 in cisplatin-resistant human ovarian tumor cells

EGF receptor and p21WAF1 expression are reciprocally altered as ME-180 cervical carcinoma cells progress from high to low cisplatin sensitivity

Effect of a specific 5HT uptake inhibitor (citalopram) on drug accumulation by rat lung slices

Effect of adriamycin combined with whole body hyperthermia on tumor and normal tissues

Effect of carboplatin combined with whole body hyperthermia on normal tissue and tumor in rats

Effect of whole body hyperthermia on cis-diamminedichloroplatinum (II)-induced antitumour activity and tissue Pt-distribution: do anaesthetics influence the therapeutic ratio?

Enhanced sensitivity of human colon tumor cell lines in vitro in response to thermochemoimmunotherapy ⬇️

Expression of p53 in cisplatin-resistant ovarian cancer cell lines: modulation with the novel platinum analogue (1R, 2R-diaminocyclohexane)(trans-diacetato)(dichloro)-platinum(IV)

Extracorporeal hemofiltration: a model for decreasing systemic drug exposure with intra-arterial chemotherapy

Fever-range whole body thermotherapy combined with oxaliplatin: a curative regimen in a pre-clinical breast cancer model

Gadolinium texaphyrin (Gd-Tex)-malonato-platinum conjugates: synthesis and comparison with carboplatin in normal and Pt-resistant cell lines

Glutathione-mediated modulation of tetraplatin activity against sensitive and resistant tumor cells.

Haematological toxicity of carboplatin and cisplatin combined with whole body hyperthermia in rats

Hepatic cytochrome P-450-dependent metabolism and enzymatic conjugation of foreign compounds in vitamin A-deficient rats

In vitro and in vivo murine metabolism of spirogermanium ⬇️

Increased doxorubicin levels in hepatic tumors with reduced systemic drug exposure achieved with complete hepatic venous isolation and extracorporeal chemofiltration

Increased sensitivity of a metastatic model of prostate cancer to a novel tetravalent platinum analog.

Increased therapeutic efficacy induced by tumor necrosis factor alpha combined with platinum complexes and whole-body hyperthermia in rats ⬇️

Increased therapeutic gain of combined cis-diamminedichloroplatinum (II) and whole body hyperthermia therapy by optimal heat/drug scheduling

Independent pathways of p53 induction by cisplatin and X-rays in a cisplatin-resistant ovarian tumor cell line ⬇️

Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities

Kinetics of tissue disposition of cis-ammine/cyclohexylamine-dichloroplatinum(II) and cisplatin in mice bearing FSaIIC tumors

Lack of correlation between cortisol-induced precocious maturation of the fetal rabbit lung and drug metabolism ⬇️

Metabolism and biliary excretion of sulfobromophthalein in vitamin A deficiency

Model platinum nucleobase and nucleoside complexes and antitumor activity: X-ray crystal structure of [PtIV(trans-1R,2R-diaminocyclohexane)trans-(acetate)2(9-ethylguanine)Cl]NO3.H2O.

Modulation of cytotoxicity and cellular pharmacology of 1,2-diaminocyclohexane platinum (IV) complexes mediated by axial and equatorial ligands

Modulatory effect of axial and equatorial ligands on antitumor activities of trans-1R,2R-diaminocyclohexane platinum(IV) complexes

Oncolytic HSV therapy modulates vesicular trafficking inducing cisplatin sensitivity and anti-tumor immunity

Organ distribution and tumor uptake of liposome entrapped cis-bis-neodecanoato trans-R, R-1,2 diaminocyclohexane platinum (II) administered intravenously and into the proper hepatic artery

Overcoming biochemical pharmacologic mechanisms of platinum resistance with a texaphyrin–platinum conjugate ⬇️

Overexpression of edg-2/vzg-1 induces apoptosis and anoikis in ovarian cancer cells in a lysophosphatidic acid-independent manner

Oxaliplatin Pt(IV) prodrugs conjugated to gadolinium-texaphyrin as potential antitumor agents

PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis

Pharmacokinetics of intravenously injected [3H]tetrachloro(D,L-trans)1,2-diaminocyclohexane platinum (IV) (tetraplatin) in mice ⬇️

Pharmacokinetics of liposome-entrapped cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II) and cisplatin given i.v. and i.p. in the rat

Pharmacokinetics of tetraplatin administered intraperitoneally with reduced glutathione in mice.

Phase I clinical and pharmacological study of intraperitoneal cis-bis-neodecanoato( trans- R, R-1, 2-diaminocyclohexane)-platinum II entrapped in multilamellar liposome vesicles

Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions

Phase I study of azacitidine and oxaliplatin in patients with advanced cancers that have relapsed or are refractory to any platinum therapy

Photoinduced reduction of Pt(IV) within an anti-proliferative Pt(IV)-texaphyrin conjugate

Physiologic and pathologic drug resistance in ovarian carcinoma--a hypothesis based on a clonal progression model

Platinum(IV)-Ferrocene Conjugates and Their Cyclodextrin Host-Guest Complexes

Preparation, characterization, and antitumor activity of new cisplatin analogs with homopiperazines: crystal structure of [PtII(1-methylhomopiperazine)(methylmalonato)].2H2O.

Preparation, characterization, and antitumor activity of new cisplatin analogues with 1-methyl-4-(methylamino)piperidine: crystal structure of [PtII(1-methyl-4-(methylamino) piperidine)(oxalate)].

Preparation, characterization, and antitumor activity of new ethylenediamine platinum(IV) complexes containing mixed carboxylate ligands

Preparation, characterization, and antitumor activity of water-soluble aminoalkanol platinum(II) complexes

Protective effect of ICRF-187 against normal tissue injury induced by adriamycin in combination with whole body hyperthermia

Protein expression profiling identifies differential modulation of homologous recombination by platinum-based antitumor agents

Protein kinase inhibitors emodin and dichloro-ribofuranosylbenzimidazole modulate the cellular accumulation and cytotoxicity of cisplatin in a schedule-dependent manner

Pulmonary accumulation of drugs in vitamin A deficiency

Recent developments in texaphyrin chemistry and drug discovery

Recruitment of trimeric proliferating cell nuclear antigen by G1-phase cyclin-dependent kinases following DNA damage with platinum-based antitumour agents

Relative pulmonary toxicity and antitumor effects of two new bleomycin analogs, pepleomycin and tallysomycin A