Lista de obras -

A canine study of immunotherapy in scorpion envenomation.

artículo científico publicado en 2003

A comparative evaluation of different DNA vaccine candidates against experimental murine leishmaniasis due to L. major

artículo científico publicado en 2004

A novel simple and rapid PCR-based site-directed mutagenesis method

scientific article published on 01 January 2004

Absence of coronaviruses, paramyxoviruses, and influenza A viruses in seabirds in the southwestern Indian Ocean

artículo científico publicado en 2013

Alain Michault, PharmD (1950–2015).

artículo científico publicado en 2016

An eco-epidemiological study of Morbilli-related paramyxovirus infection in Madagascar bats reveals host-switching as the dominant macro-evolutionary mechanism

artículo científico publicado en 2016

Analysis of granzyme B activity as a surrogate marker of Leishmania-specific cell-mediated cytotoxicity in zoonotic cutaneous leishmaniasis

artículo científico publicado en 2004

Anti-thrombomodulin antibodies and venous thrombosis

artículo científico publicado en 2004

Avian cholera outbreaks threaten seabird species on Amsterdam Island.

artículo científico publicado en 2018

Biogeography of Leptospira in wild animal communities inhabiting the insular ecosystem of the western Indian Ocean islands and neighboring Africa

artículo científico publicado en 2018

Characterization of two different mucolipin-like genes from Leishmania major

artículo científico publicado en 2005

Clinical and genetic heterogeneity of inherited autosomal recessive susceptibility to disseminated Mycobacterium bovis bacille calmette-guérin infection

artículo científico publicado en 2002

Community-acquired poliovirus infection in children with primary immunodeficiencies in Tunisia

artículo científico publicado en 2003

Comparative evaluation of ELISAs based on ten recombinant or purified Leishmania antigens for the serodiagnosis of Mediterranean visceral leishmaniasis

artículo científico publicado en 2003

Comparative evaluation of two vaccine candidates against experimental leishmaniasis due to Leishmania major infection in four inbred mouse strains.

artículo científico publicado en 2009

Consanguinity, endogamy, and genetic disorders in Tunisia.

artículo científico publicado en 2012

Contribution to the description of the beta-thalassemia spectrum in Tunisia and the origin of mutation diversity

artículo científico publicado en 2004

Cytogenetic Assessment of Fanconi Anemia in Children With Aplastic Anemia in Tunisia ⬇️

artículo científico publicado el 1 de octubre de 2013

DNA based vaccination with a cocktail of plasmids encoding immunodominant Leishmania (Leishmania) major antigens confers full protection in BALB/c mice

artículo científico publicado en 2008

Deciphering arboviral emergence within insular ecosystems

artículo científico publicado en 2012

Development of real-time RT-PCR for the detection of low concentrations of Rift Valley fever virus

artículo científico publicado en 2013

Diversification of an emerging pathogen in a biodiversity hotspot: Leptospira in endemic small mammals of Madagascar.

artículo científico publicado en 2014

Diversity, Host Specialization, and Geographic Structure of Filarial Nematodes Infecting Malagasy Bats

artículo científico publicado en 2016

Do scars caused by past history of Leishmania major infection may harbor persistent parasites?

artículo científico publicado en 2011

Enhanced patient serum immunoreactivity to recombinant Mycobacterium tuberculosis CFP32 produced in the yeast Pichia pastoris compared to Escherichia coli and its potential for serodiagnosis of tuberculosis

artículo científico publicado en 2006

Fanconi anemia in Tunisia: high prevalence of group A and identification of new FANCA mutations.

artículo científico publicado en 2003

Fanconi anemia: contribution of molecular analyses to the identification of bone marrow graft donors and the study of chimerism in grafted patients

artículo científico publicado en 2004

Field trials of a very potent rabies DNA vaccine which induced long lasting virus neutralizing antibodies and protection in dogs in experimental conditions

artículo científico publicado en 2005

Fleas of small mammals on Reunion Island: diversity, distribution and epidemiological consequences ⬇️

artículo científico publicado en 2014

Founder mutations in Tunisia: implications for diagnosis in North Africa and Middle East

artículo científico publicado en 2012

Frequency and spectrum of hemochromatosis mutations in Tunisia

artículo científico publicado en 2003

Gene expression analysis of wild Leishmania major isolates: identification of genes preferentially expressed in amastigotes

artículo científico publicado en 2006

Genetic heterogeneity of megaloblastic anaemia type 1 in Tunisian patients.

artículo científico publicado en 2007

Genetic micro-heterogeneity of Leishmania major in emerging foci of zoonotic cutaneous leishmaniasis in Tunisia

artículo científico publicado en 2016

Hb A2-Pasteur-Tunis [delta59(E3)Lys-->Asn, AAG-->AAC]: a new delta chain variant detected by DNA sequencing in a Tunisian carrier of the codon 39 (C-->T) beta0-Thalassemia mutation

artículo científico publicado en 2007

Heterogeneity of hepatitis B transmission in Tunisia: risk factors for infection and chronic carriage before the introduction of a universal vaccine program

artículo científico publicado en 2010

High frequency of exon 15 deletion in the FANCA gene in Tunisian patients affected with Fanconi anemia disease: implication for diagnosis.

scientific article published on 05 February 2014

High level production and purification of human interferon α2b in high cell density culture of Pichia pastoris.

artículo científico publicado en 2007

High prevalence of hepatitis E in humans and pigs and evidence of genotype-3 virus in swine, Madagascar

artículo científico publicado en 2012

Highly diverse morbillivirus-related paramyxoviruses in wild fauna of the southwestern Indian Ocean Islands: evidence of exchange between introduced and endemic small mammals

artículo científico publicado en 2014

Human Leptospirosis on Reunion Island, Indian Ocean: Are Rodents the (Only) Ones to Blame?

artículo científico publicado en 2016

Human leptospirosis in Seychelles: A prospective study confirms the heavy burden of the disease but suggests that rats are not the main reservoir

artículo científico

Identification of Tenrec ecaudatus, a Wild Mammal Introduced to Mayotte Island, as a Reservoir of the Newly Identified Human Pathogenic Leptospira mayottensis

artículo científico publicado en 2016

Identification of a new developmentally regulated Leishmania major large RAB GTPase

artículo científico publicado en 2006

Identification of novel paramyxoviruses in insectivorous bats of the Southwest Indian Ocean

artículo científico publicado en 2012

Immunity Against Infection: Parasite-Specific Granzyme B Induction as a Correlate of Protection

scholarly article by Thouraya Boussoffara et al published 2018 in Frontiers in cellular and infection microbiology

Immunogenicity and efficacy of an in-house developed cell-culture derived veterinarian rabies vaccine.

artículo científico publicado en 2006

Inbred strains derived from feral mice reveal new pathogenic mechanisms of experimental leishmaniasis due to Leishmania major.

artículo científico publicado en 2004

Influenza A virus on oceanic islands: host and viral diversity in seabirds in the Western Indian Ocean

artículo científico publicado en 2015

Influenza A(H1N1)pdm09 virus in pigs, Réunion Island

artículo científico publicado en 2012

Influenza C virus high seroprevalence rates observed in 3 different population groups

artículo científico publicado en 2014

Intense co-circulation of non-influenza respiratory viruses during the first wave of pandemic influenza pH1N1/2009: a cohort study in Reunion Island

artículo científico publicado en 2012

Isolation and characterization of human neutralizing antibodies to rabies virus derived from a recombinant immune antibody library

artículo científico publicado en 2009

Leishmania initially activates but subsequently down-regulates intracellular mitogen-activated protein kinases and nuclear factor-kappaB signaling in macrophages

artículo científico publicado en 2008

Leishmania major amastigotes induce p50/c-Rel NF-kappa B transcription factor in human macrophages: involvement in cytokine synthesis

scientific article published on May 2004

Leishmania major parasites induced macrophage tolerance: implication of MAPK and NF-kappaB pathways

artículo científico publicado en 2009

Leptospira and paramyxovirus infection dynamics in a bat maternity enlightens pathogen maintenance in wildlife.

artículo científico publicado en 2015

Malagasy bats shelter a considerable genetic diversity of pathogenic Leptospira suggesting notable host-specificity patterns

artículo científico publicado en 2016

Massive infection of seabird ticks with bacterial species related to Coxiella burnetii

artículo científico publicado en 2014

Mechanisms of the natural reactivity of lymphocytes from noninfected individuals to membrane-associated Leishmania infantum antigens

artículo científico publicado en 2005

Megaloblastic anemia in North Africa.

artículo científico publicado en 2006

Methodology optimizing SAGE library tag-to-gene mapping: application to Leishmania ⬇️

artículo científico publicado el 27 de enero de 2012

MicroRNA expression profile in human macrophages in response to Leishmania major infection

artículo científico publicado en 2013

Molecular evolutionary analysis of pH1N1 2009 influenza virus in Reunion Island, South West Indian Ocean region: a cohort study

artículo científico publicado en 2012

Molecular spectrum of alpha-thalassemia in Tunisia: epidemiology and detection at birth

artículo científico publicado en 2002

Molecular study of Fanconi anemia in Tunisia ⬇️

artículo científico publicado en 2004

Pandemic influenza due to pH1N1/2009 virus: estimation of infection burden in Reunion Island through a prospective serosurvey, austral winter 2009.

artículo científico publicado en 2011

Pathogenic Leptospira and their animal reservoirs: testing host specificity through experimental infection

scientific article published on 29 April 2020

Pathogenic Leptospira spp. in bats, Madagascar and Union of the Comoros

artículo científico publicado en 2012

Peptide mimotopes of rabies virus glycoprotein with immunogenic activity

artículo científico publicado en 2009

Polychromophilus spp. (Haemosporida) in Malagasy bats: host specificity and insights on invertebrate vectors

scholarly article published by Pablo Tortosa in 2018

Post-exposure therapy in mice against experimental rabies: a single injection of DNA vaccine is as effective as five injections of cell culture-derived vaccine ⬇️

artículo científico publicado el 12 de diciembre de 2003

Promoter and neck region length variation of DC-SIGN is not associated with susceptibility to tuberculosis in Tunisian patients

artículo científico publicado en 2007

Proteomic approach for characterization of immunodominant membrane-associated 30- to 36-kiloDalton fraction antigens of Leishmania infantum promastigotes, reacting with sera from Mediterranean visceral leishmaniasis patients

artículo científico publicado en 2005

Rabies in Tunisia during the 19th century: case increase or disease emergence?

artículo científico publicado en 2007

Random amplified polymorphic DNA technique for identification and differentiation of old world Leishmania species

artículo científico publicado en 2002

Recombinant single-chain Fv antibody fragment-alkaline phosphatase conjugate: a novel in vitro tool to estimate rabies viral glycoprotein antigen in vaccine manufacture

artículo científico publicado en 2007

Rickettsia and Bartonella species in fleas from Reunion Island

artículo científico publicado en 2015

Rickettsia spp. in seabird ticks from western Indian Ocean islands, 2011-2012.

artículo científico publicado en 2014

Selection of endogenous reference genes for gene expression analysis in Leishmania major developmental stages

artículo científico publicado en 2007

Serologic evidence of leptospirosis in humans, Union of the Comoros, 2011

artículo científico publicado en 2014

Serological Evidence of Contrasted Exposure to Arboviral Infections between Islands of the Union of Comoros (Indian Ocean).

artículo científico publicado en 2016

Serological Evidence of Lyssaviruses among Bats on Southwestern Indian Ocean Islands

artículo científico publicado en 2016

Simultaneous gene expression profiling in human macrophages infected with Leishmania major parasites using SAGE

artículo científico publicado en 2008

Single autologous stem-cell transplantation followed by maintenance therapy with thalidomide is superior to double autologous transplantation in multiple myeloma: results of a multicenter randomized clinical trial

artículo científico publicado en 2007

The hyper-IgM syndrome: 13 observations

artículo científico publicado el 29 de marzo de 2003

The influenza A (H1N1) pandemic in Reunion Island: knowledge, perceived risk and precautionary behaviour

artículo científico publicado en 2013

The predictive validity of naturally acquired delayed-type hypersensitivity to leishmanin in resistance to Leishmania major-associated cutaneous leishmaniasis

artículo científico publicado en 2005

The role of seabirds of the Iles Eparses as reservoirs and disseminators of parasites and pathogens

scientific article published on 12 January 2016

Three Strains From Western Indian Ocean Wildlife Show Highly Distinct Virulence Phenotypes Through Hamster Experimental Infection

artículo científico publicado en 2019

Toll-like receptor 2 Arg677Trp polymorphism is associated with susceptibility to tuberculosis in Tunisian patients

artículo científico publicado en 2004

Tuberculosis due to resistant Haarlem strain, Tunisia

artículo científico publicado en 2005

Use of Taguchi's methods as a basis to optimize hybridoma cell line growth and antibody production in a spinner flask

artículo científico publicado en 2002

WR279,396, a third generation aminoglycoside ointment for the treatment of Leishmania major cutaneous leishmaniasis: a phase 2, randomized, double blind, placebo controlled study

artículo científico publicado en 2009

Zooprophylaxis: impact of breeding rabbits around houses on reducing the indoor abundance of Phlebotomus papatasi.

artículo científico publicado en 2008

Lista de obras de

A canine study of immunotherapy in scorpion envenomation.

A comparative evaluation of different DNA vaccine candidates against experimental murine leishmaniasis due to L. major

A novel simple and rapid PCR-based site-directed mutagenesis method

Absence of coronaviruses, paramyxoviruses, and influenza A viruses in seabirds in the southwestern Indian Ocean

Alain Michault, PharmD (1950–2015).

An eco-epidemiological study of Morbilli-related paramyxovirus infection in Madagascar bats reveals host-switching as the dominant macro-evolutionary mechanism

Analysis of granzyme B activity as a surrogate marker of Leishmania-specific cell-mediated cytotoxicity in zoonotic cutaneous leishmaniasis

Anti-thrombomodulin antibodies and venous thrombosis

Avian cholera outbreaks threaten seabird species on Amsterdam Island.

Biogeography of Leptospira in wild animal communities inhabiting the insular ecosystem of the western Indian Ocean islands and neighboring Africa

Characterization of two different mucolipin-like genes from Leishmania major

Clinical and genetic heterogeneity of inherited autosomal recessive susceptibility to disseminated Mycobacterium bovis bacille calmette-guérin infection

Community-acquired poliovirus infection in children with primary immunodeficiencies in Tunisia

Comparative evaluation of ELISAs based on ten recombinant or purified Leishmania antigens for the serodiagnosis of Mediterranean visceral leishmaniasis

Comparative evaluation of two vaccine candidates against experimental leishmaniasis due to Leishmania major infection in four inbred mouse strains.

Consanguinity, endogamy, and genetic disorders in Tunisia.

Contribution to the description of the beta-thalassemia spectrum in Tunisia and the origin of mutation diversity

Cytogenetic Assessment of Fanconi Anemia in Children With Aplastic Anemia in Tunisia ⬇️

DNA based vaccination with a cocktail of plasmids encoding immunodominant Leishmania (Leishmania) major antigens confers full protection in BALB/c mice

Deciphering arboviral emergence within insular ecosystems

Development of real-time RT-PCR for the detection of low concentrations of Rift Valley fever virus

Diversification of an emerging pathogen in a biodiversity hotspot: Leptospira in endemic small mammals of Madagascar.

Diversity, Host Specialization, and Geographic Structure of Filarial Nematodes Infecting Malagasy Bats

Do scars caused by past history of Leishmania major infection may harbor persistent parasites?

Enhanced patient serum immunoreactivity to recombinant Mycobacterium tuberculosis CFP32 produced in the yeast Pichia pastoris compared to Escherichia coli and its potential for serodiagnosis of tuberculosis

Fanconi anemia in Tunisia: high prevalence of group A and identification of new FANCA mutations.

Fanconi anemia: contribution of molecular analyses to the identification of bone marrow graft donors and the study of chimerism in grafted patients

Field trials of a very potent rabies DNA vaccine which induced long lasting virus neutralizing antibodies and protection in dogs in experimental conditions

Fleas of small mammals on Reunion Island: diversity, distribution and epidemiological consequences ⬇️

Founder mutations in Tunisia: implications for diagnosis in North Africa and Middle East

Frequency and spectrum of hemochromatosis mutations in Tunisia

Gene expression analysis of wild Leishmania major isolates: identification of genes preferentially expressed in amastigotes

Genetic heterogeneity of megaloblastic anaemia type 1 in Tunisian patients.

Genetic micro-heterogeneity of Leishmania major in emerging foci of zoonotic cutaneous leishmaniasis in Tunisia

Hb A2-Pasteur-Tunis [delta59(E3)Lys-->Asn, AAG-->AAC]: a new delta chain variant detected by DNA sequencing in a Tunisian carrier of the codon 39 (C-->T) beta0-Thalassemia mutation

Heterogeneity of hepatitis B transmission in Tunisia: risk factors for infection and chronic carriage before the introduction of a universal vaccine program

High frequency of exon 15 deletion in the FANCA gene in Tunisian patients affected with Fanconi anemia disease: implication for diagnosis.

High level production and purification of human interferon α2b in high cell density culture of Pichia pastoris.

High prevalence of hepatitis E in humans and pigs and evidence of genotype-3 virus in swine, Madagascar

Highly diverse morbillivirus-related paramyxoviruses in wild fauna of the southwestern Indian Ocean Islands: evidence of exchange between introduced and endemic small mammals

Human Leptospirosis on Reunion Island, Indian Ocean: Are Rodents the (Only) Ones to Blame?

Human leptospirosis in Seychelles: A prospective study confirms the heavy burden of the disease but suggests that rats are not the main reservoir

Identification of Tenrec ecaudatus, a Wild Mammal Introduced to Mayotte Island, as a Reservoir of the Newly Identified Human Pathogenic Leptospira mayottensis

Identification of a new developmentally regulated Leishmania major large RAB GTPase

Identification of novel paramyxoviruses in insectivorous bats of the Southwest Indian Ocean

Immunity Against Infection: Parasite-Specific Granzyme B Induction as a Correlate of Protection

Immunogenicity and efficacy of an in-house developed cell-culture derived veterinarian rabies vaccine.

Inbred strains derived from feral mice reveal new pathogenic mechanisms of experimental leishmaniasis due to Leishmania major.

Influenza A virus on oceanic islands: host and viral diversity in seabirds in the Western Indian Ocean

Influenza A(H1N1)pdm09 virus in pigs, Réunion Island

Influenza C virus high seroprevalence rates observed in 3 different population groups

Intense co-circulation of non-influenza respiratory viruses during the first wave of pandemic influenza pH1N1/2009: a cohort study in Reunion Island

Isolation and characterization of human neutralizing antibodies to rabies virus derived from a recombinant immune antibody library

Leishmania initially activates but subsequently down-regulates intracellular mitogen-activated protein kinases and nuclear factor-kappaB signaling in macrophages

Leishmania major amastigotes induce p50/c-Rel NF-kappa B transcription factor in human macrophages: involvement in cytokine synthesis

Leishmania major parasites induced macrophage tolerance: implication of MAPK and NF-kappaB pathways

Leptospira and paramyxovirus infection dynamics in a bat maternity enlightens pathogen maintenance in wildlife.

Malagasy bats shelter a considerable genetic diversity of pathogenic Leptospira suggesting notable host-specificity patterns

Massive infection of seabird ticks with bacterial species related to Coxiella burnetii

Mechanisms of the natural reactivity of lymphocytes from noninfected individuals to membrane-associated Leishmania infantum antigens

Megaloblastic anemia in North Africa.

Methodology optimizing SAGE library tag-to-gene mapping: application to Leishmania ⬇️

MicroRNA expression profile in human macrophages in response to Leishmania major infection

Molecular evolutionary analysis of pH1N1 2009 influenza virus in Reunion Island, South West Indian Ocean region: a cohort study

Molecular spectrum of alpha-thalassemia in Tunisia: epidemiology and detection at birth

Molecular study of Fanconi anemia in Tunisia ⬇️

Pandemic influenza due to pH1N1/2009 virus: estimation of infection burden in Reunion Island through a prospective serosurvey, austral winter 2009.

Pathogenic Leptospira and their animal reservoirs: testing host specificity through experimental infection

Pathogenic Leptospira spp. in bats, Madagascar and Union of the Comoros

Peptide mimotopes of rabies virus glycoprotein with immunogenic activity

Polychromophilus spp. (Haemosporida) in Malagasy bats: host specificity and insights on invertebrate vectors

Post-exposure therapy in mice against experimental rabies: a single injection of DNA vaccine is as effective as five injections of cell culture-derived vaccine ⬇️

Promoter and neck region length variation of DC-SIGN is not associated with susceptibility to tuberculosis in Tunisian patients

Proteomic approach for characterization of immunodominant membrane-associated 30- to 36-kiloDalton fraction antigens of Leishmania infantum promastigotes, reacting with sera from Mediterranean visceral leishmaniasis patients

Rabies in Tunisia during the 19th century: case increase or disease emergence?

Random amplified polymorphic DNA technique for identification and differentiation of old world Leishmania species

Recombinant single-chain Fv antibody fragment-alkaline phosphatase conjugate: a novel in vitro tool to estimate rabies viral glycoprotein antigen in vaccine manufacture

Rickettsia and Bartonella species in fleas from Reunion Island

Rickettsia spp. in seabird ticks from western Indian Ocean islands, 2011-2012.