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A methodological framework to enhance the clinical success of cancer immunotherapy

artículo científico publicado el 13 de octubre de 2011

A neoepitope generated by an FLT3 internal tandem duplication (FLT3-ITD) is recognized by leukemia-reactive autologous CD8+ T cells

artículo científico publicado en 2007

A phase I dose-escalation study of IMAB362 (Zolbetuximab) in patients with advanced gastric and gastro-oesophageal junction cancer

artículo científico publicado en 2018

A phase I vaccination study with tyrosinase in patients with stage II melanoma using recombinant modified vaccinia virus Ankara (MVA-hTyr).

artículo científico publicado en 2004

A placenta-specific gene ectopically activated in many human cancers is essentially involved in malignant cell processes

artículo científico publicado en 2007

Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 19 December 2018

Altered expression of nonclassical HLA class Ib antigens in human renal cell carcinoma and its association with impaired immune response

artículo científico publicado en 2003

An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma

artículo científico publicado en 2020

An immune escape screen reveals Cdc42 as regulator of cancer susceptibility to lymphocyte-mediated tumor suppression

scientific article published on 30 October 2007

An open-label, prospective phase I/II study evaluating the immunogenicity and safety of a ras peptide vaccine plus GM-CSF in patients with non-small cell lung cancer

scientific article published on 27 June 2007

Analysis of the structural integrity of the TAP2 gene in renal cell carcinoma

scientific article published on 01 October 2003

Aortic root dimensions among patients with severe aortic stenosis undergoing transcatheter aortic valve replacement

artículo científico publicado en 2013

Atrial fibrillation and aortic stenosis: impact on clinical outcomes among patients undergoing transcatheter aortic valve implantation

artículo científico publicado en 2013

Awareness and understanding of cancer immunotherapy in Europe

artículo científico publicado en 2014

CD8+ cytotoxic T lymphocytes isolated from allogeneic healthy donors recognize HLA class Ia/Ib-associated renal carcinoma antigens with ubiquitous or restricted tissue expression

artículo científico publicado en 2004

Cancer classification using the Immunoscore: a worldwide task force

artículo científico publicado en 2012

Cerebrovascular accidents complicating transcatheter aortic valve implantation: frequency, timing and impact on outcomes

artículo científico publicado en 2012

Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation

artículo científico publicado el 1 de mayo de 2003

Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development

artículo científico publicado en 2008

Clinical outcome and predictors for adverse events after transcatheter aortic valve implantation with the use of different devices and access routes

artículo científico publicado en 2011

Clinical outcome of high-risk patients with severe aortic stenosis and reduced left ventricular ejection fraction undergoing medical treatment or TAVI

artículo científico publicado en 2011

Clinical outcomes and revascularization strategies in patients with low-flow, low-gradient severe aortic valve stenosis according to the assigned treatment modality

artículo científico publicado en 2015

Clinical outcomes of patients with estimated low or intermediate surgical risk undergoing transcatheter aortic valve implantation

scientific article published on 13 March 2013

Clinical outcomes of patients with severe aortic stenosis at increased surgical risk according to treatment modality

artículo científico publicado en 2011

Cloning and functional analyses of the mouse tapasin promoter

artículo científico publicado en 2003

Coexpression of the T-cell receptor constant alpha domain triggers tumor reactivity of single-chain TCR-transduced human T cells

artículo científico publicado en 2010

Comparison of procedural and clinical outcomes with Evolut R versus Medtronic CoreValve: a Swiss TAVI registry analysis

artículo científico publicado en 2017

Cooperation of Human Tumor-Reactive CD4+ and CD8+ T Cells after Redirection of Their Specificity by a High-Affinity p53A2.1-Specific TCR

artículo científico publicado en 2005

Coronary artery disease severity and aortic stenosis: clinical outcomes according to SYNTAX score in patients undergoing transcatheter aortic valve implantation

artículo científico publicado en 2014

CrELISA: a fast and robust enzyme-linked immunosorbent assay bypassing the need for purification of recombinant protein.

artículo científico publicado en 2004

Current results on the use of imatinib mesylate in patients with relapsed philadelphia chromosome positive leukemia after allogeneic or syngeneic hematopoietic stem cell transplantation

artículo científico publicado el 1 de septiembre de 2003

Defining the critical hurdles in cancer immunotherapy

artículo científico publicado en 2011

Detection of a germline mutation and somatic homozygous loss of the von Hippel-Lindau tumor-suppressor gene in a family with a de novo mutation

article

Dissection and molecular analysis of alloreactive CD8+ T cell responses in allogeneic haematopoietic stem cell transplantation

artículo científico publicado en 2007

Editorial Comment: Re-operation: a thing of the past? Transcatheter aortic valve-in-valve implantation for failed surgical bioprosthesis

artículo científico publicado el 16 de marzo de 2012

Effect of Pulmonary Hypertension Hemodynamic Presentation on Clinical Outcomes in Patients With Severe Symptomatic Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation: Insights From the New Proposed Pulmonary Hypertension Classi

artículo científico publicado en 2015

Effect of resting heart rate on two-year clinical outcomes of high-risk patients with severe symptomatic aortic stenosis undergoing transcatheter aortic valve implantation

artículo científico publicado en 2016

Efficacy and safety of imatinib in adult patients with c-kit-positive acute myeloid leukemia

artículo científico publicado en 2004

Erratum: Mutant MHC class II epitopes drive therapeutic immune responses to cancer

artículo científico publicado en 2015

Evaluation of genetic melanoma vaccines in cdk4-mutant mice provides evidence for immunological tolerance against authochthonous melanomas in the skin.

artículo científico publicado en 2006

Expanding Indications of Transcatheter Heart Valve Interventions

artículo científico publicado en 2015

Exploiting the mutanome for tumor vaccination.

artículo científico publicado en 2012

Expression of multiple epigenetically regulated cancer/germline genes in nonsmall cell lung cancer

artículo científico publicado en 2006

FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines

artículo científico publicado en 2011

Frequent nonrandom activation of germ-line genes in human cancer

artículo científico publicado en 2004

Functional role of human leukocyte antigen-G up-regulation in renal cell carcinoma

artículo científico publicado en 2003

Graft preservation solutions in cardiovascular surgery.

artículo científico publicado en 2016

High frequency of a non-functional TAP1/LMP2 promoter polymorphism in human tumors

artículo científico publicado el 1 de febrero de 2002

Identification of T cell epitopes by the use of rapidly generated mRNA fragments

artículo científico publicado en 2005

Impact of coronary artery disease and percutaneous coronary intervention on outcomes in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation

artículo científico publicado en 2011

Impact of mitral regurgitation on clinical outcomes of patients with low-ejection fraction, low-gradient severe aortic stenosis undergoing transcatheter aortic valve implantation

artículo científico publicado en 2015

Impact of new technologies and experience on procedural aspects of surgical aortic valve replacement - a process analysis

artículo científico publicado en 2017

Impact of permanent pacemaker implantation on clinical outcome among patients undergoing transcatheter aortic valve implantation

artículo científico publicado en 2012

Impaired transporter associated with antigen processing (TAP) function attributable to a single amino acid alteration in the peptide TAP subunit TAP1.

artículo científico publicado en 2003

Increased Antigen Presentation Efficiency by Coupling Antigens to MHC Class I Trafficking Signals

artículo científico publicado en 2008

Increased tumorigenicity, but unchanged immunogenicity, of transporter for antigen presentation 1-deficient tumors

artículo científico publicado en 2002

Infective Endocarditis After Transcatheter Aortic Valve Replacement

scientific article published on 01 June 2020

Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity.

artículo científico publicado en 2010

Is surgery in acute aortic dissection type A still contraindicated in the presence of preoperative neurological symptoms?

artículo científico publicado en 2015

Long-term follow-up after implantation of the Shelhigh® No-React® complete biological aortic valved conduit

artículo científico publicado en 2015

Long-term outcome of elderly patients with severe aortic stenosis as a function of treatment modality

artículo científico publicado en 2014

MS4A12 is a colon-selective store-operated calcium channel promoting malignant cell processes

artículo científico publicado en 2008

Minimally invasive extracorporeal circulation: excellent outcome and life expectancy after coronary artery bypass grafting surgery

artículo científico

Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells

artículo científico publicado en 2006

Molecular design of the Calphabeta interface favors specific pairing of introduced TCRalphabeta in human T cells

scientific article published on 01 January 2008

Multiple splice variants of lactate dehydrogenase C selectively expressed in human cancer.

artículo científico publicado en 2002

Mutant MHC class II epitopes drive therapeutic immune responses to cancer

artículo científico publicado en 2015

Partial tyrosinase-specific self tolerance by HLA-A*0201-restricted cytotoxic T lymphocytes in mice and man

artículo científico publicado en 2004

Percutaneous Transcatheter Closure for Aortic Puncture and Paravalvular Leak Closure With the New Amplatzer III Device

artículo científico publicado en 2015

Percutaneous management of vascular complications in patients undergoing transcatheter aortic valve implantation

artículo científico publicado en 2012

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

artículo científico publicado en 2017

Pitfalls in TAMVI: experience with the repositionable Lotus® Valve System

artículo científico publicado en 2017

Predicting Mortality After Transcatheter Aortic Valve Replacement: External Validation of the Transcatheter Valve Therapy Registry Model.

artículo científico publicado en 2017

Predictors of clinical outcomes in patients with severe aortic stenosis undergoing TAVI: a multistate analysis

artículo científico publicado en 2012

Predictors of functional decline in elderly patients undergoing transcatheter aortic valve implantation (TAVI).

artículo científico publicado en 2012

Procedural Results and Clinical Outcomes of Transcatheter Aortic Valve Implantation in Switzerland: An Observational Cohort Study of Sapien 3 Versus Sapien XT Transcatheter Heart Valves

artículo científico

Proteasome-inhibited dendritic cells demonstrate improved presentation of exogenous synthetic and natural HLA-class I peptide epitopes

artículo científico publicado en 2005

Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 01 February 2019

Quality of life in high-risk patients: comparison of transcatheter aortic valve implantation with surgical aortic valve replacement

artículo científico publicado en 2012

Rapid and sensitive identification of major histocompatibility complex class I-associated tumor peptides by Nano-LC MALDI MS/MS.

artículo científico publicado en 2005

Rapid identification and sorting of viable virus-reactive CD4(+) and CD8(+) T cells based on antigen-triggered CD137 expression

artículo científico publicado en 2008

Rapid identification of an HLA-B*1501-restricted vaccinia peptide antigen

artículo científico publicado en 2007

Recovery of varicella-zoster virus-specific T cell immunity after T cell-depleted allogeneic transplantation requires symptomatic virus reactivation

artículo científico publicado en 2008

Redirection of T cells by delivering a transgenic mouse-derived MDM2 tumor antigen-specific TCR and its humanized derivative is governed by the CD8 coreceptor and affects natural human TCR expression

artículo científico publicado en 2006

Reduced-intensity conditioning followed by allografting of CD34-selected stem cells and < or =10(6)/kg T cells may have an adverse effect on transplant-related mortality

artículo científico publicado en 2005

Repositionable Versus Balloon-Expandable Devices for Transcatheter Aortic Valve Implantation in Patients With Aortic Stenosis

artículo científico publicado en 2016

Response To Letter Regarding Article, "Effect of Pulmonary Hypertension Hemodynamic Presentation on Clinical Outcomes in Patients With Severe Symptomatic Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation: Insights From the New

artículo científico publicado en 2015

Results of a multicenter phase II trial for older patients with c-Kit-positive acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (HR-MDS) using low-dose Ara-C and Imatinib

artículo científico publicado en 2007

Second valve implantation for the treatment of a malpositioned transcatheter aortic valve

artículo científico publicado en 2012

Selective activation of trophoblast-specific PLAC1 in breast cancer by CCAAT/enhancer-binding protein beta (C/EBPbeta) isoform 2.

scientific article published on 03 August 2009

Selective activation of tumor growth-promoting Ca2+ channel MS4A12 in colon cancer by caudal type homeobox transcription factor CDX2.

artículo científico publicado en 2009

Selective depletion of alloreactive T lymphocytes using patient-derived nonhematopoietic stimulator cells in allograft engineering

artículo científico publicado en 2008

SeroGRID: an improved method for the rapid selection of antigens with disease related immunogenicity.

artículo científico publicado en 2003

Short-term clinical outcomes among patients undergoing transcatheter aortic valve implantation in Switzerland: the Swiss TAVI registry

scholarly article by Peter Wenaweser et al published December 2014 in EuroIntervention

Simplified Approach for Repair of Early Pseudoaneurysm of the Left Coronary Button Following Composite Graft Due to Acute Type A Aortic Dissection

artículo científico publicado en 2016

Simultaneous ex vivo quantification of antigen-specific CD4+ and CD8+ T cell responses using in vitro transcribed RNA

article

Successful adenovirus-mediated wild-type p53 gene transfer in patients with bladder cancer by intravesical vector instillation

article

Superior antitumor in vitro responses of allogeneic matched sibling compared with autologous patient CD8+ T cells

artículo científico publicado en 2006

Surgical antegrade transcatheter mitral valve implantation for symptomatic mitral valve disease and heavily calcified annulus

scientific article published on 01 February 2017

Sustained complete hematologic remission after administration of the tyrosine kinase inhibitor imatinib mesylate in a patient with refractory, secondary AML.

artículo científico publicado en 2002

Sustained complete molecular remissions after treatment with imatinib-mesylate in patients with failure after allogeneic stem cell transplantation for chronic myelogenous leukemia: results of a prospective phase II open-label multicenter study

artículo científico publicado en 2005

Sustained remissions and low rate of BCR-ABL resistance mutations with imatinib treatment chronic myelogenous leukemia in patients treated in late chronic phase: a 5-year follow up

scientific article published on 01 March 2008

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

artículo científico publicado en 2016

Targeting AKT signaling sensitizes cancer to cellular immunotherapy

artículo científico publicado en 2008

Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer

artículo científico publicado en 2007

Targeting positive regulatory domain I-binding factor 1 and X box-binding protein 1 transcription factors by multiple myeloma-reactive CTL

artículo científico publicado en 2005

Targeting the Heterogeneity of Cancer with Individualized Neoepitope Vaccines.

artículo científico publicado en 2016

Targeting the activation-induced antigen CD137 can selectively deplete alloreactive T cells from antileukemic and antitumor donor T-cell lines

artículo científico publicado en 2006

Temporal Trends in Adoption and Outcomes of Transcatheter Aortic Valve Implantation: A Swisstavi Registry Analysis

artículo científico publicado en 2019

The European Regulatory Environment of RNA-Based Vaccines

artículo científico publicado en 2017

The hospital results and 1-year outcomes of transcatheter aortic valve-in-valve procedures and transcatheter aortic valve implantations in the native valves: the results from the Swiss-TAVI Registry

scientific article published on 01 July 2019

The human X chromosome is enriched for germline genes expressed in premeiotic germ cells of both sexes

artículo científico publicado en 2006

The kinase inhibitor LS104 induces apoptosis, enhances cytotoxic effects of chemotherapeutic drugs and is targeting the receptor tyrosine kinase FLT3 in acute myeloid leukemia

artículo científico publicado en 2008

The regulatory landscape for actively personalized cancer immunotherapies

article published in 2013

The response of autologous T cells to a human melanoma is dominated by mutated neoantigens

artículo científico publicado en 2005

The role of the reporting framework MIATA within current efforts to advance immune monitoring

scholarly article by Sylvia Janetzki et al published July 2014 in Journal of Immunological Methods

The self-expanding Symetis Acurate does not increase cerebral microembolic load when compared to the balloon-expandable Edwards Sapien prosthesis: a transcranial Doppler study in patients undergoing transapical aortic valve implantation

artículo científico publicado en 2014

The use of clonal mRNA as an antigenic format for the detection of antigen-specific T lymphocytes in IFN-gamma ELISPOT assays

artículo científico publicado en 2004

Therapeutic vaccines for cancer: an overview of clinical trials

artículo científico

Transapical transcatheter aortic valve implantation using the second-generation self-expanding Symetis ACURATE TA valve

artículo científico publicado en 2014

Transcarotid aortic valve-in-valve implantation for degenerated stentless aortic root conduits with severe regurgitation: a case series

artículo científico publicado en 2015

Transcatheter aortic valve implantation or surgical aortic valve replacement as redo procedure after prior coronary artery bypass grafting

artículo científico publicado en 2011

Transcranial Doppler-detected cerebral embolic load during transcatheter aortic valve implantation

artículo científico publicado en 2011

Transporter (TAP)‐ and proteasome‐independent presentation of a melanoma‐associated tyrosinase epitope

Validation of 3D-reconstructed computed tomography images using OsiriX® software for pre-transcatheter aortic valve implantation aortic annulus sizing

artículo científico publicado en 2017

Validation of the Valve Academic Research Consortium Bleeding Definition in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation.

artículo científico publicado en 2015

mTOR inhibition improves antitumor effects of vaccination with antigen-encoding RNA.

artículo científico publicado en 2013