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A MMP derived versican neo-epitope is elevated in plasma from patients with atherosclerotic heart disease ⬇️

artículo científico publicado el 21 de marzo de 2013

A Serological Biomarker of Versican Degradation is Associated with Mortality Following Acute Exacerbations of Idiopathic Interstitial Pneumonia

artículo científico publicado en 2018

ADAPT: An Algorithm Incorporating PRO-C3 Accurately Identifies Patients With NAFLD and Advanced Fibrosis

artículo científico publicado en 2019

Accelerated extracellular matrix turnover during exacerbations of COPD.

artículo científico publicado en 2015

Acute Myocardial Infarction and Pulmonary Diseases Result in Two Different Degradation Profiles of Elastin as Quantified by Two Novel ELISAs

artículo científico publicado en 2013

Acute decompensation boosts hepatic collagen type III deposition and deteriorates experimental and human cirrhosis

artículo científico publicado en 2018

Addition of trans fat and alcohol has divergent effects on atherogenic diet-induced liver injury in rodent models of steatohepatitis

scientific article published on 06 January 2020

Alpha C-telopeptide of type I collagen is associated with subchondral bone turnover and predicts progression of joint space narrowing and osteophytes in osteoarthritis

artículo científico publicado en 2014

Alpha CTX as a biomarker of skeletal invasion of breast cancer: immunolocalization and the load dependency of urinary excretion

scientific article published on 01 July 2006

Alterations in osteoclast function and phenotype induced by different inhibitors of bone resorption--implications for osteoclast quality

artículo científico publicado en 2010

Ankylosing spondylitis is characterized by an increased turnover of several different metalloproteinase-derived collagen species: a cross-sectional study ⬇️

artículo científico publicado el 16 de noviembre de 2011

Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis

artículo científico publicado en 2011

Association of systemic collagen type IV formation with survival among patients undergoing hemodialysis

artículo científico publicado en 2013

Association of versican turnover with all-cause mortality in patients on haemodialysis.

artículo científico publicado en 2014

Biochemical and histological characterisation of an experimental rodent model of non-alcoholic steatohepatitis - Effects of a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist and a glucagon-like peptide-1 analogue

scientific article published on 07 January 2019

Biochemical approach to the detection and monitoring of metastatic bone disease: What do we know and what questions need answers?

artículo científico publicado en 2006

Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort

scientific article published on 12 July 2019

Biomarkers of collagen turnover are related to annual change in FEV1 in patients with chronic obstructive pulmonary disease within the ECLIPSE study

artículo científico publicado en 2017

Characterization of serological neo-epitope biomarkers reflecting collagen remodeling in clinically stable chronic obstructive pulmonary disease

artículo científico publicado en 2016

Circulating levels of PRO-C3 reflect liver fibrosis and liver function in HIV positive patients receiving modern cART

artículo científico publicado en 2019

Circulating levels of citrullinated and MMP-degraded vimentin (VICM) in liver fibrosis related pathology ⬇️

artículo científico publicado el 10 de octubre de 2012

Circulating protein fragments of cartilage and connective tissue degradation are diagnostic and prognostic markers of rheumatoid arthritis and ankylosing spondylitis

artículo científico publicado en 2013

Clinical evaluation of a matrix metalloproteinase-12 cleaved fragment of titin as a cardiovascular serological biomarker.

artículo científico publicado en 2012

Collagen Degradation and Formation Are Elevated in Exacerbated COPD Compared With Stable Disease

artículo científico publicado en 2018

Collagen Formation Assessed by N-Terminal Propeptide of Type 3 Procollagen Is a Heritable Trait and Is Associated With Liver Fibrosis Assessed by Magnetic Resonance Elastography

artículo científico publicado en 2019

Collagen biology and non-invasive biomarkers of liver fibrosis

scientific article published on 19 February 2020

Combined antiretroviral therapy attenuates hepatic extracellular matrix remodeling in HIV patients assessed by novel protein fingerprint markers.

artículo científico publicado en 2014

Combining biomarkers of clot resolution and alveolar basement membrane destruction predicts mortality in the ECLIPSE COPD cohort

scientific article published on 02 October 2020

Comparison of ADAPT, FIB-4 and APRI as non-invasive predictors of liver fibrosis and NASH within the CENTAUR screening population

artículo científico publicado en 2021

Development of a Neo-Epitope Specific Assay for Serological Assessment of Type VII Collagen Turnover and Its Relevance in Fibroproliferative Disorders

artículo científico publicado en 2018

Does increased local bone resorption secondary to breast and prostate cancer result in increased cartilage degradation?

artículo científico publicado en 2008

Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort

artículo científico publicado en 2020

Enhanced processing of von Willebrand factor reflects disease severity and discriminates severe portal hypertension in cirrhosis

artículo científico publicado en 2019

Enzyme-linked immunosorbent assay (ELISAs) for metalloproteinase derived type II collagen neoepitope, CIIM--increased serum CIIM in subjects with severe radiographic osteoarthritis

scientific article published on 09 January 2011

Enzyme-linked immunosorbent serum assay specific for the 7S domain of Collagen Type IV (P4NP 7S): A marker related to the extracellular matrix remodeling during liver fibrogenesis

scientific article published on 05 January 2012

Evaluation of cartilage damage by measuring collagen degradation products in joint extracts in a traumatic model of osteoarthritis

artículo científico publicado en 2008

Excessive matrix metalloprotease-mediated degradation of interstitial tissue (type I collagen) independently predicts short-term survival in an observational study of postmenopausal women diagnosed with cancer

artículo científico publicado en 2017

Extracellular matrix remodeling: the common denominator in connective tissue diseases. Possibilities for evaluation and current understanding of the matrix as more than a passive architecture, but a key player in tissue failure

artículo científico publicado en 2012

Extracellular matrix specific protein fingerprints measured in serum can separate pancreatic cancer patients from healthy controls

artículo científico publicado en 2013

Fibrogenesis assessed by serological type III collagen formation identifies patients with progressive liver fibrosis and responders to a potential antifibrotic therapy.

artículo científico publicado en 2016

High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD - results from the ECLIPSE study.

scientific article published on 04 October 2016

High turnover of extracellular matrix reflected by specific protein fragments measured in serum is associated with poor outcomes in two metastatic breast cancer cohorts

artículo científico publicado en 2018

Immunological detection of the type V collagen propeptide fragment, PVCP-1230, in connective tissue remodeling associated with liver fibrosis ⬇️

artículo científico publicado el 25 de mayo de 2011

Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study

artículo científico publicado en 2015

Markers of Basement Membrane Remodeling Are Associated With Higher Mortality in Patients With Known Atherosclerosis

artículo científico publicado en 2018

Markers of Collagen Remodeling Detect Clinically Significant Fibrosis in Chronic Hepatitis C Patients

artículo científico publicado en 2015

Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation

artículo científico publicado en 2012

Molecular serum markers of liver fibrosis.

artículo científico

Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non-Small Cell Lung Cancer

artículo científico publicado en 2017

Novel insights into the function and dynamics of extracellular matrix in liver fibrosis

artículo científico publicado en 2015

PRO-C3-levels in patients with HIV/HCV-Co-infection reflect fibrosis stage and degree of portal hypertension

artículo científico publicado en 2014

Peptidyl arginine deiminase inhibitor effect on hepatic fibrogenesis in a CCl4 pre-clinical model of liver fibrosis ⬇️

artículo científico publicado el 24 de mayo de 2013

Performance of the PRO-C3 collagen neo-epitope biomarker in non-alcoholic fatty liver disease

scientific article published on 04 July 2019

Pro-C5, a marker of true type V collagen formation and fibrillation, correlates with portal hypertension in patients with alcoholic cirrhosis.

artículo científico publicado en 2015

Protein fingerprinting of the extracellular matrix remodelling in a rat model of liver fibrosis--a serological evaluation

artículo científico publicado en 2012

Remodeling of the Tumor Microenvironment Predicts Increased Risk of Cancer in Postmenopausal Women: The Prospective Epidemiologic Risk Factor (PERF I) Study

artículo científico publicado en 2016

Review article: the signalling and functional role of the extracellular matrix in the development of liver fibrosis

artículo científico publicado en 2020

Serological identification of fast progressors of structural damage with rheumatoid arthritis.

artículo científico publicado en 2013

Serological investigation of the collagen degradation profile of patients with chronic obstructive pulmonary disease or idiopathic pulmonary fibrosis

artículo científico publicado en 2012

Serum Type XIX Collagen is Significantly Elevated in Non-Small Cell Lung Cancer: A Preliminary Study on Biomarker Potential

scientific article published on 09 June 2020

Serum biomarkers reflecting specific tumor tissue remodeling processes are valuable diagnostic tools for lung cancer

artículo científico publicado en 2014

Serum endotrophin identifies optimal responders to PPARγ agonists in type 2 diabetes.

artículo científico publicado en 2016

Serum markers of the extracellular matrix remodeling reflect antifibrotic therapy in bile-duct ligated rats.

artículo científico publicado en 2013

The neo-epitope specific PRO-C3 ELISA measures true formation of type III collagen associated with liver and muscle parameters

artículo científico publicado en 2013

The relative use of eight collagenous and noncollagenous markers for diagnosis of skeletal metastases in breast, prostate, or lung cancer patients

artículo científico publicado en 2006

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

scientific article published on 16 September 2020

Turnover of type III collagen reflects disease severity and is associated with progression and microinflammation in patients with IgA nephropathy

Unique insight into microenvironmental changes in colorectal cancer: Ex vivo assessment of matrix metalloprotease-mediated molecular changes in human colorectal tumor tissue and corresponding non-neoplastic adjacent tissue

artículo científico publicado en 2017

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