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A Phase 1/1b Study Evaluating Trametinib Plus Docetaxel or Pemetrexed in Patients With Advanced Non-Small Cell Lung Cancer

artículo científico publicado en 2016

A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer

artículo científico publicado en 2017

A phase I/II study combining erlotinib and dasatinib for non-small cell lung cancer

artículo científico publicado en 2014

Adding Erlotinib to Chemoradiation Improves Overall Survival but Not Progression-Free Survival in Stage III Non-Small Cell Lung Cancer

artículo científico publicado en 2015

Advanced malignancies treated with a combination of the VEGF inhibitor bevacizumab, anti-EGFR antibody cetuximab, and the mTOR inhibitor temsirolimus

artículo científico publicado en 2016

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance

artículo científico publicado en 2012

Angiogenesis inhibitors for lung cancer: clinical developments and future directions.

artículo científico publicado en 2006

Asian ethnicity as a predictor of response in patients with non-small-cell lung cancer treated with gefitinib on an expanded access program

artículo científico publicado en 2006

Association between glutathione S-transferase pi polymorphisms and survival in patients with advanced nonsmall cell lung carcinoma

scientific article published on 01 January 2006

Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer

artículo científico publicado en 2018

CheckMate 141: 1-Year Update and Subgroup Analysis of Nivolumab as First-Line Therapy in Patients with Recurrent/Metastatic Head and Neck Cancer

artículo científico publicado en 2018

Clinical and biomarker outcomes of the phase II vandetanib study from the BATTLE trial

artículo científico publicado en 2013

Clinical and pharmacokinetic study of TNP-470, an angiogenesis inhibitor, in combination with paclitaxel and carboplatin in patients with solid tumors

artículo científico publicado en 2004

Clinical outcomes and biomarker profiles of elderly pretreated NSCLC patients from the BATTLE trial

artículo científico publicado en 2012

Comparison of outcomes for patients with unresectable, locally advanced non-small-cell lung cancer treated with induction chemotherapy followed by concurrent chemoradiation vs. concurrent chemoradiation alone

artículo científico publicado en 2007

Comprehensive biomarker analysis and final efficacy results of sorafenib in the BATTLE trial

artículo científico publicado en 2013

Developmental antiangiogenic agents for the treatment of non-small cell lung cancer (NSCLC).

artículo científico

Differential expression of hormonal and growth factor receptors in salivary duct carcinomas: biologic significance and potential role in therapeutic stratification of patients

artículo científico publicado en 2007

Dose-dense therapy with a novel irinotecan regimen for small-cell lung cancer

artículo científico publicado en 2003

Durable Response to Chemotherapy for Recurrent Squamous Cell Carcinoma of the Cheek With Perineural Spread

article

EGFR expression and survival in patients given cetuximab and chemoradiation for stage III non-small cell lung cancer: a secondary analysis of RTOG 0324.

artículo científico publicado en 2014

Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome

artículo científico publicado en 2012

Effects of amifostine on acute toxicity from concurrent chemotherapy and radiotherapy for inoperable non-small-cell lung cancer: report of a randomized comparative trial

artículo científico publicado en 2004

Ensartinib (X-396) in ALK-Positive Non-Small Cell Lung Cancer: Results from a First-in-Human Phase I/II, Multicenter Study.

artículo científico publicado en 2018

Epidermal Growth Factor Receptor P753S Mutation in Cutaneous Squamous Cell Carcinoma Responsive to Cetuximab-Based Therapy

artículo científico publicado en 2016

Epidermal growth factor receptor inhibitors in development for the treatment of non-small cell lung cancer

artículo científico publicado en 2006

Feasibility of image-guided transthoracic core-needle biopsy in the BATTLE lung trial

artículo científico publicado en 2013

First-In-Human Phase I Study Of A Dual mTOR Kinase And DNA-PK Inhibitor (CC-115) In Advanced Malignancy

scientific article published on 13 December 2019

First-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung Cancer.

artículo científico publicado en 2017

First-in-Human, Multicenter, Phase I Dose-Escalation and Expansion Study of Anti-Mesothelin Antibody-Drug Conjugate Anetumab Ravtansine in Advanced or Metastatic Solid Tumors

scientific article published on 26 March 2020

Frequency of mesenchymal-epithelial transition factor gene (MET) and the catalytic subunit of phosphoinositide-3-kinase (PIK3CA) copy number elevation and correlation with outcome in patients with early stage breast cancer

artículo científico publicado en 2012

Immunotherapy for non-small cell lung cancer--novel approaches to improve patient outcome

artículo científico publicado en 2013

Immunotherapy for non-small cell lung cancer: novel approaches to improve patient outcome

artículo científico

Influence of technologic advances on outcomes in patients with unresectable, locally advanced non-small-cell lung cancer receiving concomitant chemoradiotherapy

artículo científico publicado en 2009

Insulin-like growth factor receptor

artículo científico publicado en 2011

Integration of Targeted Therapies in Gemcitabine Chemotherapy Regimens

artículo científico publicado el 1 de enero de 2003

Intraarterial cisplatin with intravenous paclitaxel and ifosfamide as an organ-preservation approach in patients with paranasal sinus carcinoma

artículo científico publicado en 2003

Local Consolidative Therapy Vs. Maintenance Therapy or Observation for Patients With Oligometastatic Non-Small-Cell Lung Cancer: Long-Term Results of a Multi-Institutional, Phase II, Randomized Study

scientific article published on 08 May 2019

Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer without progression after first-line systemic therapy: a multicentre, randomised, controlled, phase 2 study

artículo científico

Long-Term Results of NRG Oncology RTOG 0617: Standard- Versus High-Dose Chemoradiotherapy With or Without Cetuximab for Unresectable Stage III Non-Small-Cell Lung Cancer

scientific article published on 16 December 2019

Long-term safety and tolerability of sorafenib in patients with advanced non-small-cell lung cancer: a case-based review

artículo científico publicado en 2011

MINI01.02: Response and Plasma Genotyping from Phase I/II Trial of Ensartinib (X-396) in Patients (pts) with ALK+ NSCLC: Topic: Medical Oncology

artículo científico publicado en 2016

Merkel cell carcinoma of the eyelid with a positive sentinel node.

artículo científico publicado en 2002

Mesothelin expression and survival outcomes in triple receptor negative breast cancer

scientific article published on 27 June 2013

Monitoring Therapeutic Response and Resistance: Analysis of Circulating Tumor DNA in Patients With ALK+ Lung Cancer

scientific article published on 22 August 2019

Motesanib and advanced NSCLC: experiences and expectations

artículo científico publicado el 2 de mayo de 2011

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck

artículo científico publicado en 2016

Nivolumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: Efficacy and Safety in CheckMate 141 by Prior Cetuximab Use

artículo científico publicado en 2019

Nivolumab treatment beyond RECIST-defined progression in recurrent or metastatic squamous cell carcinoma of the head and neck in CheckMate 141: A subgroup analysis of a randomized phase 3 clinical trial

scientific article published on 27 June 2019

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer

artículo científico publicado en 2015

Nivolumab versus investigator's choice in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: Efficacy and safety in CheckMate 141 by age

artículo científico publicado en 2019

Nivolumab versus standard, single-agent therapy of investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141): health-related quality-of-life results from a randomised, phase 3 trial.

artículo científico publicado en 2017

Nivolumab vs investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck: 2-year long-term survival update of CheckMate 141 with analyses by tumor PD-L1 expression

artículo científico publicado en 2018

Outcomes of patients with advanced cancer and KRAS mutations in phase I clinical trials

artículo científico publicado en 2014

P1.44 (also presented as PD2.02): Phase I/II Trial of X-396, A Novel ALK Inhibitor, in Patients With ALK+ NSCLC: Track: Advanced NSCLC.

artículo científico publicado en 2016

PD-L1 Expression, Tumor Mutational Burden, and Cancer Gene Mutations Are Stronger Predictors of Benefit from Immune Checkpoint Blockade than HLA Class I Genotype in Non-Small Cell Lung Cancer

scientific article published on 16 February 2019

PD2.02 (also presented as P1.44): Phase I/II Trial of X-396, a Novel ALK Inhibitor, in Patients With ALK+ NSCLC.

artículo científico publicado en 2016

PS01.59: CheckMate 370: A Master Protocol of Phase 1/2 Studies of Nivolumab as Maintenance or First-Line ± Standard-of-Care Therapies in Advanced NSCLC: Topic: Medical Oncology.

artículo científico publicado en 2016

Pharmacokinetic study of the phase III, randomized, double-blind, multicenter trial (TRIBUTE) of paclitaxel and carboplatin combined with erlotinib or placebo in patients with advanced Non-small Cell Lung Cancer (NSCLC)

artículo científico publicado en 2010

Phase 1/2 Study of the Safety and Tolerability of Nivolumab Plus Crizotinib for the First-Line Treatment of Anaplastic Lymphoma Kinase Translocation - Positive Advanced Non-Small Cell Lung Cancer (CheckMate 370).

artículo científico publicado en 2018

Phase 1b study of motesanib, an oral angiogenesis inhibitor, in combination with carboplatin/paclitaxel and/or panitumumab for the treatment of advanced non-small cell lung cancer

artículo científico publicado en 2009

Phase 1b/2 Randomized Study of MEDI-575 in Combination With Carboplatin Plus Paclitaxel Versus Carboplatin Plus Paclitaxel Alone in Adult Patients With Previously Untreated Advanced Non-Small-Cell Lung Cancer

scientific article published on 29 November 2018

Phase I Study of Weekly Alternating Therapy with Irinotecan/Cisplatin and Etoposide/Cisplatin for Patients with Small-Cell Lung Cancer

artículo científico publicado el 1 de julio de 2003

Phase I study of celecoxib with concurrent irinotecan, Cisplatin, and radiation therapy for patients with unresectable locally advanced non-small cell lung cancer

artículo científico publicado en 2011

Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lun

artículo científico publicado en 2005

Phase I/IIa study of cetuximab with gemcitabine plus carboplatin in patients with chemotherapy-naive advanced non-small-cell lung cancer

artículo científico publicado en 2005

Phase II Study of Dasatinib in Patients With Advanced Non–Small-Cell Lung Cancer

artículo científico publicado el 20 de septiembre de 2010

Phase II Trial of Concurrent Atezolizumab With Chemoradiation for Unresectable NSCLC

scientific article published on 25 November 2019

Phase II study of cetuximab in combination with chemoradiation in patients with stage IIIA/B non-small-cell lung cancer: RTOG 0324

artículo científico publicado en 2011

Phase II study of gefitinib in patients with advanced salivary gland cancers

artículo científico publicado en 2015

Phase II study of pemetrexed in combination with carboplatin in the first-line treatment of advanced nonsmall cell lung cancer

artículo científico publicado en 2005

Phase II study of tariquidar, a selective P-glycoprotein inhibitor, in patients with chemotherapy-resistant, advanced breast carcinoma

artículo científico publicado en 2005

Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer.

artículo científico publicado en 2009

Phase II trial of induction chemotherapy followed by surgery for squamous cell carcinoma of the oral tongue in young adults

artículo científico publicado en 2011

Phase II trial of single-agent foretinib (GSK1363089) in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.

artículo científico publicado en 2012

Phase II trial of the histone deacetylase inhibitor vorinostat (Zolinza, suberoylanilide hydroxamic acid, SAHA) in patients with recurrent and/or metastatic head and neck cancer

artículo científico publicado en 2007

Phase II trials of imatinib mesylate and docetaxel in patients with metastatic non-small cell lung cancer and head and neck squamous cell carcinoma

artículo científico publicado en 2011

Phase II, multicenter, uncontrolled trial of single-agent sorafenib in patients with relapsed or refractory, advanced non-small-cell lung cancer

artículo científico publicado en 2009

Phase III trial comparing carboplatin, paclitaxel, and bexarotene with carboplatin and paclitaxel in chemotherapy-naive patients with advanced or metastatic non-small-cell lung cancer: SPIRIT II.

artículo científico publicado en 2008

Phase Ib Trial of the PI3K Inhibitor Copanlisib Combined with the Allosteric MEK Inhibitor Refametinib in Patients with Advanced Cancer

artículo científico publicado en 2020

Plasma biomarkers correlating with clinical outcome in a phase II study of sorafenib in advanced NSCLC

artículo científico publicado en 2011

Pooled Analysis of Individual Patient Data on Concurrent Chemoradiotherapy for Stage III Non-Small-Cell Lung Cancer in Elderly Patients Compared With Younger Patients Who Participated in US National Cancer Institute Cooperative Group Studies.

artículo científico publicado en 2017

Programmed Death Ligand 1 Heterogeneity and its Impact on Benefit from Immune Checkpoint Inhibitors in Non-Small-Cell Lung Cancer

scientific article published on 07 May 2020

Randomized phase II multicenter trial of two schedules of lapatinib as first- or second-line monotherapy in patients with advanced or metastatic non-small cell lung cancer

artículo científico publicado en 2010

Role of HGF/MET axis in resistance of lung cancer to contemporary management

artículo científico publicado en 2012

Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors.

artículo científico publicado en 2015

Safety and pharmacokinetic effects of TNP-470, an angiogenesis inhibitor, combined with paclitaxel in patients with solid tumors: evidence for activity in non-small-cell lung cancer

artículo científico publicado en 2002

Sorafenib in lung cancer: clinical developments and future directions

scientific article published on June 2008

Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two facto

artículo científico publicado en 2015

Summary statement novel agents in the treatment of lung cancer: Fifth Cambridge Conference assessing opportunities for combination therapy

artículo científico publicado en 2008

Sunitinib in combination with paclitaxel plus carboplatin in patients with advanced solid tumors: phase I study results

artículo científico publicado en 2010

Sunitinib plus erlotinib for the treatment of advanced/metastatic non-small-cell lung cancer: a lead-in study

artículo científico publicado en 2012

Targeting the hepatocyte growth factor-cMET axis in cancer therapy

artículo científico publicado en 2012

The BATTLE trial: personalizing therapy for lung cancer

artículo científico publicado en 2011

The novel and effective nonplatinum, nontaxane combination of gemcitabine and vinorelbine in advanced nonsmall cell lung carcinoma: potential for decreased toxicity and combination with biological therapy

artículo científico publicado en 2002

Time to treatment as a quality metric in lung cancer: Staging studies, time to treatment, and patient survival

artículo científico publicado en 2015

Treatment and outcomes for metastatic sebaceous cell carcinoma of the eyelid

artículo científico publicado en 2008

Tumor cavitation during therapy with antiangiogenesis agents in patients with lung cancer

artículo científico publicado en 2008

Weekly alternating therapy with irinotecan plus cisplatin and etoposide plus cisplatin in the treatment of patients with extensive small cell lung carcinoma

artículo científico publicado en 2010

cMET and phospho-cMET protein levels in breast cancers and survival outcomes

artículo científico publicado en 2012